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Seeing Is Not Believing: Counterfactual Lesion Erasure Teaches a Small Medical Vision-Language Agent to Report Only What the Image Shows

arXiv AI · WORLD · AI · 11/11/2026, 12:00:00 AM

arXiv:2611.13006v1 Announce Type: new Abstract: Medical vision-language models (VLMs) often report a finding because the question names it; standard benchmarks miss this. From public segmentation datasets we build counterfactual views without manual annotation: the lesion erased by inpainting, a same-shape control edit elsewhere, and unedited lesion-free images. The evidence sensitivity gap (ESG) is the rate of absent-or-refer answers after erasure minus the rate after the control edit; it is zero for a model that ignores the image or reacts to both edits alike. MedScope-4B (Qwen3.5-4B, LoRA, image tools) was trained on label-derived trajectories, selected by a pre-registered rule and tested once against nine frontier and six open VLMs; four pre-registered checks then probed the mechanism. On 507 internal cases across five imaging types, MedScope-4B reached ESG 0.758 and claimed an erased lesion in 9.6% of cases, against 0.27-0.47 and 41-62% for the frontier models (all p<0.001), without significant loss of accuracy on real lesions. Without counterfactual views ESG fell to 0.279+-0.107 (three seeds); the effect replicated on MedGemma 1.5 4B and two unseen inpainting tools. At four external centres the advantage held but frontier models detected more real lesions; on a fresh external test MedScope-4B detected 0 of 48 pneumothorax films, with net utility below gemini-4-argon's (-0.36 [-0.50, -0.23]). Matching the control edit was not shown to matter; over three seeds no fresh-external ESG advantage over removal-based DPO was established; a paired-view consistency objective did not beat a matched-compute control, while that continuation alone cut erased-lesion claims on unseen tools at every seed, at a cost in sensitivity at one. Training on erased and edited images gives a small model an evidence-gated disposition that prompting does not give frontier models; it does not improve perception, and rare critical findings need coverage.

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