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AlphaFold 3 predicts complex immune interactions using protein sequences alone

Phys.org · WORLD · Science · 11/4/2026, 2:20:01 PM

Researchers at the Translational Genomics Research Institute (TGen), part of City of Hope, have developed a new approach using the artificial intelligence platform AlphaFold 3 to predict whether a T cell receptor will recognize a specific antigen based solely on its genetic sequence. The advancement could help scientists more rapidly decode immune responses to infectious diseases, tumors and other health threats.

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