,,ii #aaith ,,congress #b;d ,session ,s4 #diia ,,in ,,the ,,senate ,,of ,,the ,,united ,,states ,july #ae1 #bjbf,mr4 ,rounds 7for himself and ,mr4 ,heinrich7 introduced the following bill2 which was read twice and referred to the ,committee on ,energy and ,natural ,resources ,a ,,bill ,to direct the ,secretary of ,energy to establish an extremophile whole genome sequencing initiative1 and for other purposes4 #a4 ,short title ,this ,act may be cited as the ,homestake ,,ai ,act of #bjbf4 #b4 ,extremophile whole genome sequencing initiative 7a7 ,definitions ,in this section3 7#a7 ,covered facility ,the term covered facility means the long-term storage facility planned for under subsection 7c77#a77;,e74 7#b7 ,initiative ,the term initiative means the extremophile whole genome sequencing initiative established under subsection 7b74 7#c7 ,secretary ,the term ,secretary means the ,secretary of ,energy1 acting through the ,undersecretary of ,science4 7b7 ,establishment ,not later than #ij days after the date of enactment of this ,act1 the ,secretary shall establish an initiative1 to be known as the extremophile whole genome sequencing initiative1 that shall-- 7#a7 be consistent with the goals of the ,genesis ,mission announced in ,executive ,order #adcfc 7#ij ,fed4 ,reg4 #eejce2 relating to launching the ,genesis ,mission72 and 7#b7 facilitate the collection of new genomic data that will contribute to advances in scientific discovery and may support the development of new healthcare treatments4 7c7 ,initiative 7#a7 ,in general ,under the initiative1 the ,secretary shall-- 7,a7 collect1 catalogue1 and sequence the whole genomes and metabolites of samples from animals1 plants1 fungi1 and microbes found in locations selected under paragraph 7#c72 7,b7 establish a database for the data collected under subparagraph 7,a71 or use an existing database1 such as the database of the ,national ,center for ,biotechnology ,information1 including sequence data1 genome assemblies1 peptides1 metabolite data1 annotations1 and associated metadata1 including genome and transcriptome data1 metabolome data1 and proteome data2 7,c7 collaborate with industry1 academia1 and other government agencies to collate existing relevant data for inclusion in the database established or used under subparagraph 7,b72 7,d7 make that database accessible to persons in the ,united ,states1 subject to the condition that the ,secretary shall1 to the maximum extent practicable1 prevent the sharing of such information with adversary nations or foreign persons2 and 7,e7 not later than #a year after the date of enactment of this ,act1 develop a plan for the construction of a new long-term storage facility-- 7i7 for1 at a minimum1 the samples collected under subparagraph 7,a72 and 7ii7 in such a manner that the facility may continue to operate in the case of a catastrophic incident 7as defined in section #fjb of the ,post-,katrina ,emergency ,management ,reform ,act of #bjjf 7#f ,u4,s4,c4 #gja774 7#b7 ,third party collection ,the ,secretary may enter into contracts with third party entities1 including institutions of higher education or private sector entities1 to collect samples under paragraph 7#a77;,a74 7#c7 ,locations for collection 7,a7 ,in general ,not later than #ahj days after the date of enactment of this ,act1 the ,secretary shall select not fewer than #e locations from which to collect samples under paragraph 7#a77;,a71 at least #a of which shall be a mine or former mine that-- 7i7 is deeper than #d1ejj feet2 and 7ii7 houses an underground science facility4 7,b7 ,considerations 7i7 ,in general ,the ,secretary shall select locations under subparagraph 7,a7-- 7,i7 that are unique or are exposed to unique properties1 such as extreme heat or pressure2 7,,ii7 that are under risk of destruction before #bjej from natural or unnatural forces2 7,,iii7 based on the potential for finding useful organisms that will contribute to advances in scientific research and discovery2 and 7,,iv7 that may support the development of new healthcare treatments relating to cancer1 including cancers affecting children and individuals with high mortality rates1 diabetes1 and dementia1 including ,alzheimer's disease4 7ii7 ,preference ,in selecting locations under subparagraph 7,a71 the ,secretary may give preference to a location on land owned or controlled by the ,department of ,energy 7including ,national ,laboratories74 7iii7 ,range of extreme conditions ,in selecting locations under subparagraph 7,a71 the ,secretary shall ensure that the locations reflect a broad range of extreme conditions4 7#d7 ,long-term storage facility ,in selecting a location for the covered facility under the plan developed under paragraph 7#a77;,e71 the ,secretary shall consider1 among other factors determined relevant by the ,secretary-- 7,a7 colocation in a ,department of ,energy facility or a facility that receives significant funding from the ,department of ,energy2 7,b7 the benefits of storing the applicable materials underground in a remote area2 and 7,c7 the ability of the location to withstand natural disasters1 such as earthquakes1 wildfires1 or meteor strikes4 7#e7 ,data standards ,in carrying out the initiative1 the ,secretary shall-- 7,a7 leverage existing and emerging data standards to ensure-- 7i7 high-quality data are obtained under the initiative2 and 7ii7 data collected under the initiative are considered usable and interoperable1 with appropriate metadata to be included2 7,b7 ensure that data outputs under the initiative-- 7i7 7,i7 meet applicable ,federal data standards for biological data2 or 7,,ii7 if there are no applicable ,federal data standards described in subclause 7,i71 meet data standards for the initiative established by the ,secretary1 in consultation with the ,national ,institute of ,standards and ,technology and other relevant agencies1 based on findability1 accessibility1 interoperability1 and reusability data principles and using industry best practices2 and 7ii7 are updated to comply with any applicable ,united ,states ,geological ,survey standards for biological data2 and 7,c7 ensure that appropriate cybersecurity and access safeguards are implemented to protect the data generated or stored under the initiative1 including by ensuring that data outputs under the initiative are updated as necessary to meet applicable ,federal cybersecurity standards for genomic data1 including controls consistent with the ,national ,institute of ,standards and ,technology special publications #hjj-ec 7relating to ,security and ,privacy ,controls for ,information ,systems and ,organizations7 and #hjj-aaa 7relating to ,guide to ,storage ,encryption ,technologies for ,end ,user ,devices7 or any successor framework4 7#f7 ,long-term storage requirements ,the ,secretary may consult with the ,secretary of ,agriculture and the ,director of the ,national ,museum of ,natural ,history of the ,smithsonian ,institution with respect to storage capabilities for the management and long-term storage of samples collected under the initiative1 subject to the following3 7,a7 ,access to samples collected under the initiative may be managed by the respective institutional collection managers1 with-- 7i7 the natural history collections managed by the ,director of the ,national ,museum of ,natural ,history of the ,smithsonian ,institution2 and 7ii7 the germplasm repository and the covered facility managed by the ,secretary of ,agriculture4 7,b7 ,before any samples are stored at the covered facility1 the ,secretary shall-- 7i7 evaluate the species to be sampled to identify which species need to be collected for long-term storage2 and 7ii7 from among the species identified under clause 7i71 identify which species should be considered to be high-priority species4 7,c7 ,any samples identified for long-term storage under subparagraph 7,b77i7-- 7i7 shall be collected and stored at the covered facility after the covered facility is operational2 and 7ii7 may be stored in an alternative location until that date4 7,d7 ,any high-priority species identified under subparagraph 7,b77ii7 shall be collected for storage in each of-- 7i7 the natural history collections to be managed by the ,director of the ,national ,museum of ,natural ,history of the ,smithsonian ,institution2 7ii7 the germplasm repository to be managed by the ,secretary of ,agriculture2 and 7iii7 the covered facility4 7,e7 ,any physical samples collected under the initiative shall not be transferred1 exported1 or loaned outside the ,united ,states4 7,f7 ,any physical storage1 curation1 and laboratory processing of samples collected under the initiative shall occur within facilities located in the ,united ,states4 7,g7 ,the ,secretary may accept donated samples for storage from third parties or other countries4 7#g7 ,sequencing and data processing ,in carrying out the initiative1 the ,secretary shall-- 7,a7 collaborate with the ,secretary of ,agriculture1 the ,director of the ,national ,museum of ,natural ,history of the ,smithsonian ,institution1 and the heads of other applicable ,federal agencies to sequence genomic information from samples collected under the initiative2 7,b7 develop and use standardized sequencing protocols to ensure consistency and comparability of data2 and 7,c7 incorporate automated data processing and quality checks to ensure the reliability of the data4 7#h7 ,termination of collection ,no collection of samples under paragraph 7#a77;,a7 may occur by the ,secretary or a third party pursuant to a contract entered into under paragraph 7#b7 after the date that is #e years after the date of enactment of this ,act4 7d7 ,coordination with other entities 7#a7 ,in general ,in carrying out the initiative1 the ,secretary may coordinate with-- 7,a7 other offices within the ,department of ,energy2 7,b7 the ,department of ,agriculture2 7,c7 any other relevant agency that may benefit from utilizing the covered facility2 7,d7 the ,smithsonian ,institution1 including the ,national ,museum of ,natural ,history2 7,e7 the ,department of ,health and ,human ,services1 including the ,centers for ,disease ,control and ,prevention and the ,national ,institutes of ,health1 including the ,childhood ,cancer ,data ,initiative2 7,f7 academia2 7,g7 nonprofit organizations1 including organizations focused on the collection of data for the discovery of treatments for cancer1 diabetes1 and dementia1 including ,alzheimer's disease2 7,h7 nonprofit organizations that support biodiversity conservation1 including nonprofit organizations in allied countries described in subsection 7e77#b72 and 7,i7 private sector entities1 including entities in the pharmaceutical1 biotechnology1 and artificial intelligence industries4 7#b7 ,private sector contributions ,there shall be established a foundation1 which shall be an organization described in section #eja7;c77#c7 of the ,internal ,revenue ,code of #aihf and exempt from taxation under section #eja7;a7 of that ,code1 to receive in-kind contributions from biotechnology and other private sector companies to assist in carrying out the initiative and supporting the operation of the covered facility4 7#c7 ,other agency resources ,the ,secretary may use the services1 personnel1 and facilities of another agency if agreed to by that agency4 7e7 ,working group 7#a7 ,in general ,the ,secretary shall establish a working group to coordinate with private and public sector initiatives in the ,united ,states and allied countries described in paragraph 7#b7 collecting relevant genomic data to create alignment between scientific groups-- 7,a7 to maximize beneficial research output2 and 7,b7 to minimize duplicative spending of the initiative4 7#b7 ,allied countries described ,the allied countries referred to in paragraph 7#a7 are-- 7,a7 ,australia2 7,b7 member countries of the ,european ,union2 7,c7 ,japan2 7,d7 ,south ,korea2 7,e7 ,new ,zealand2 and 7,f7 the ,united ,kingdom4 7f7 ,authorization of appropriations ,there are authorized to be appropriated to the ,secretary such sums as are necessary to carry out this section4