,,ii  #aai? ,,congress  #b;d ,session   
,s4 #djfi  ,,9 ,,! ,,s5ate ,,( ,,!      
,,unit$ ,,/ates  ,m>* #ab1 #bjbf,mr4 ,"y
 7= himself & ,mr4 ,lujn7 introduc$ !   
foll[+ bill2 :i* 0 read twice & ref]r$  
to ! ,committee on ,comm]ce1 ,sci5ce1 & 
,transportation  ,a ,,bill  ,to direct !
 ,director ( ! ,national ,in/itute (    
,/&>ds & ,te*nology to e/abli%          
def9itions1 /&>ds1 res\rces1 &          
frameworks to ensure c]ta9 biological   
datasets are ready = use 9 artificial   
intellig5ce models1 & = o!r purposes4   
#a4 ,%ort title ,?is ,act may be cit$ z 
! ,,ai-,ready ,bio-,data ,/&>ds ,act4   
#b4 ,def9itions1 /&>ds1 res\rces1 &     
frameworks by ! ,national ,in/itute (   
,/&>ds & ,te*nology = c]ta9 biological  
datasets  7a7 ,e/abli%m5t  7#a7 ,9 g5]al
 ,n lat] ?an #b ye>s aft] ! date ( !    
enactm5t ( ?is ,act1 ! ,director ( !    
,national ,in/itute ( ,/&>ds &          
,te*nology 79 ?is section ref]r$ to z ! 
,director71 pursuant to recomm5dations f
 ! advisory gr\p "u subsection 7f7 &    

tak+ into acc\nt any fe$back receiv$ "u 
subsection 7e71 %all e/abli% def9itions1
 /&>ds1 res\rces1 & frameworks to ensure
 ea* biological dataset g5]at$ z a      
result ( qualifi$ f$]ally fund$ rese>*  
is artificial intellig5ce-ready4  7#b7  
,requirem5ts = def9itions1 /&>ds1       
res\rces1 & frameworks  7,a7 ,def9itions
  7i7 ,9 g5]al ,9 c>ry+ out p>agraph    
7#a71 ! ,director %all e/abli%          
def9itions = ! foll[+ t]ms3 7,i7        
,artificial intellig5ce-ready4  7,,ii7  
,biomanufactur+4  7,,iii7 ,biote*nology4
  7,,iv7 ,qualifi$ f$]ally fund$ rese>*4
  7ii7 ,requirem5ts = def9ition (       
artificial intellig5ce-ready  7,i7 ,9   
g5]al ,9 def9+ artificial               
intellig5ce-ready "u clause 7i77,i71 !  
,director %all develop a def9ition t1 :5
 appli$ to a biological dataset1        
requires t ! dataset is g5]at$ & =matt$ 
9 a mann] t-- 7aa7 enables ! effective  
use ( ! dataset = tra9+ artificial      
intellig5ce models2 &  7bb7 supports    
advancem5ts 9 rese>* relat+ to          

artificial intellig5ce & biote*nology4  
7,,ii7 ,discretion ,) respect to a      
biological dataset t o!rwise meets !    
def9ition ( artificial intellig5ce-ready
 e/abli%$ "u clause 7i77,i71 ! ,director
 may1 9 consultation ) ! ,*ief ,data    
,(fic] ( ! ,f$]al ag5cy t is responsible
 = su* biological dataset1 det]m9e t su*
 dataset is n artificial                
intellig5ce-ready4  7iii7 ,requirem5ts =
 def9ition ( qualifi$ f$]ally fund$     
rese>* ,9 def9+ qualifi$ f$]ally fund$  
rese>* "u clause 7i77,,iv71 ! ,director 
%all include c]ta9 conditions t1 if     
satisfi$1 w result 9 c]ta9 f$]ally fund$
 rese>* be+ qualifi$ f$]ally fund$      
rese>*4 ,su* conditions %all include !  
foll[+3 7,i7 ,! am\nt ( ,f$]al fund+    
aw>d$ to a recipi5t4  7,,ii7 ,!         
capability ( ! recipi5t to g5]ate a     
biological dataset1 :i* may include     
negative data1 t is artificial          
intellig5ce-ready1 reg>dless ( ! ability
 ( ! recipi5t to publi% su* dataset4    
7,,iii7 ,! exp]tise ( ! recipi5t 9      

g5]at+ a biological dataset t is        
artificial intellig5ce-ready4  7,,iv7 ,!
 size ( ! biological dataset g5]at$ by !
 recipi5t4  7,v7 ,any o!r condition !   
,director consid]s appropriate4  7,b7   
,/&>ds ,9 c>ry+ out p>agraph 7#a71 !    
,director %all e/abli% /&>ds relat+ to  
mak+ biological datasets artificial     
intellig5ce-ready1 9 accordance ) !     
def9ition ( artificial intellig5ce-ready
 e/abli%$ "u subp>agraph 7,a77i77,i7 (  
?is p>agraph4  7,c7 ,res\rces &         
frameworks ,9 c>ry+ out p>agraph 7#a71 !
 ,director %all e/abli% data managem5t  
res\rces & cyb]security frameworks = !  
foll[+3 7i7 ,f$]al dep>tm5ts & ag5cies t
 provide ei!r full or p>tial ,f$]al     
fund+ = rese>* t g5]ates biological     
datasets4  7ii7 ,f$]ally fund$ rese>*]s 
:o are collect+1 clean+1 curat+1 or     
g5]at+ biological datasets to make !    
datasets artificial intellig5ce-ready4  
7,d7 ,additional requirem5ts ,!         
,director %all ensure t ! def9itions1   
/&>ds1 res\rces1 & frameworks e/abli%$  

"u p>agraph 7#a7-- 7i7 are n ov]ly      
burd5some on recipi5ts ( fund+ =        
qualifi$ f$]ally fund$ rese>*1 su* t !  
act ( g5]at+ biological datasets t are  
artificial intellig5ce-ready requires   
res\rces & exp]tise beyond ^? available 
to ! recipi5ts2 &  7ii7 are te/$ &      
evaluat$ 9 accordance ) subsection 7c7 &
 9 consultation )-- 7,i7 ! head ( any   
,f$]al ag5cy ! ,director consid]s       
appropriate2  7,,ii7 repres5tatives f   
any private sector entity ! ,director   
consid]s appropriate2 &  7,,iii7 any    
biote*nology rese>*] ! ,director        
consid]s appropriate4  7#c7 ,annual     
updates ,n lat] ?an #a ye> aft] !       
e/abli%m5t ( ! def9itions1 /&>ds1       
res\rces1 & frameworks "u p>agraph 7#a71
 & annually !reaft]1 ! ,director %all   
review ! def9itions1 /&>ds1 res\rces1 & 
frameworks &1 if ! ,director consid]s x 
appropriate1 %all update ! def9itions1  
/&>ds1 res\rces1 & frameworks 9         
accordance ) ! requirem5ts ( ?is        
section4  7#d7 ,consultation ,to        

facilitate ! e/abli%m5t ( ! def9itions1 
/&>ds1 res\rces1 & frameworks "u        
p>agraph 7#a71 & any update "u p>agraph 
7#c71 ! ,director %all consult ) !      
foll[+3 7,a7 ,private sector entities f 
! biote*nology indu/ry4  7,b7 ,private  
sector entities f ! fronti] artificial  
intellig5ce model indu/ry4  7,c7 ,memb]s
 ( academia4  7,d7 ,! foll[+ heads (    
,f$]al ag5cies t provide fund+ =        
qualifi$ f$]ally fund$ rese>* relat+ to 
! g5]ation ( biological datasets3 7i7 ,!
 ,secret>y ( ,agriculture4  7ii7 ,!     
,secret>y ( ,def5se4  7iii7 ,! ,secret>y
 ( ,en]gy4  7iv7 ,! ,director ( !       
,national ,a]onautics & ,space          
,adm9i/ration4  7v7 ,! ,director ( !    
,national ,in/itutes ( ,heal?4  7vi7 ,! 
,adm9i/rator ( ! ,national ,sci5ce      
,f\ndation4  7vii7 ,! head ( any o!r    
,f$]al ag5cy ! ,director consid]s       
appropriate4  7#e7 ,p]sonnel ,to        
facilitate ! e/abli%m5t ( ! def9itions1 
/&>ds1 res\rces1 & frameworks "u        
p>agraph 7#a71 & any update "u p>agraph 

7#c71 ! ,director %all hire /aff z !    
,director det]m9es necess>y4  7b7       
,in=mation ga!r+  7#a7 ,9 g5]al ,n lat] 
?an #a ye> aft] ! date ( ! enactm5t (   
?is ,act1 ! ,director %all inv5tory !   
foll[+3 7,a7 ,exi/+ biote*nology /&>ds  
utiliz$ by recipi5ts ( ,f$]al fund+ =   
biote*nology rese>* to g5]ate biological
 datasets4  7,b7 ,exi/+ biological      
datasets g5]at$ by recipi5ts ( ,f$]al   
fund+ = biote*nology rese>*4  7#b7      
,publication ,n lat] ?an #a ye> aft] !  
,director completes ! inv5tory          
requirem5t "u p>agraph 7#a71 ! ,director
 %all make any in=mation inv5tori$ "u t 
p>agraph available to ! public ?r\gh a  
website ( ! ,national ,in/itute ( ,/&>ds
 & ,te*nology4  7c7 ,te/ & evaluation ,n
 lat] ?an #a ye> aft] ! date ( !        
enactm5t ( ?is ,act1 & n less frequ5tly 
?an e #b ye>s !reaft]1 ! ,director %all 
coord9ate ) ! ,adm9i/rator ( ! ,national
 ,sci5ce ,f\ndation to conduct a te/ &  
evaluation ( ! def9itions1 /&>ds1       
res\rces1 & frameworks e/abli%$ pursuant

 to subsection 7a77#a7 on a sample (    
biological datasets g5]at$ z a result ( 
qualifi$ f$]ally fund$ rese>* to det]m9e
 ! foll[+3 7#a7 ,:e!r ! def9itions1     
/&>ds1 res\rces1 & frameworks are cle>ly
 writt51 easy to foll[1 & easily        
applicable = ! g5]ation ( biological    
datasets t are artificial               
intellig5ce-ready4  7#b7 ,:e!r          
compliance ) ! def9itions1 /&>ds1       
res\rces1 & frameworks e/abli%$ "u      
subsection 7a77#a7 :5 g5]at+ or curat+  
biological datasets results 9 an undue  
burd5 on ! recipi5ts ( su* qualifi$     
f$]ally fund$ rese>*1 & if s1 h[ to     
modify ! def9itions1 /&>ds1 res\rces1 & 
frameworks1 z ! case may be1 s z to     
r$uce ! burd54  7d7 ,ag5cy-,specific    
data managem5t policies  7#a7 ,9 g5]al  
,n lat] ?an #b ye>s aft] ! date ( !     
enactm5t ( ?is ,act & 9 accordance )    
requirem5ts "u subsection 7e71 !        
,director %all e/abli% or1 if already   
e/abli%$1 review & revise ag5cy-specific
 data managem5t policies = ea* ,f$]al   

ag5cy t provides fund+ = qualifi$       
f$]ally fund$ rese>* to ensure          
implem5tation ( policies t require t any
 biological dataset g5]at$ by a recipi5t
 ( qualifi$ f$]ally fund$ rese>* is     
artificial intellig5ce-ready4  7#b7     
,elem5ts ,! data managem5t policies     
describ$ 9 p>agraph 7#a7 %all include ! 
foll[+3 7,a7 ,a me*anism to ensure      
suffici5t ,f$]al fund+ to a recipi5t to 
satisfy ! requirem5ts ( ! def9itions1   
/&>ds1 res\rces1 & frameworks e/abli%$  
"u subsection 7a77#a74  7,b7 ,a process 
= ! ,*ief ,data ,(fic] ( ea* ,f$]al     
ag5cy to designate an individual ( su*  
ag5cy to ensure compliance ) ! policies 
e/abli%$ or revis$ "u p>agraph 7#a74    
7#c7 ,ov]sight me*anisms ,z "p ( !      
ag5cy-specific data managem5t policies  
"u p>agraph 7#a71 ! ,director %all      
e/abli% ! foll[+3 7,a7 ,a regul>ly      
updat$ c5tral repository ( ! policies   
e/abli%$ at ea* ,f$]al ag5cy1 made      
available to ! public z ! ,director     
det]m9es appropriate1 = ! purpose (     

track+ available policies4  7,b7 ,a     
publicly available database to s]ve z a 
s+le po9t ( access1 updat$ z ! ,director
 det]m9es necess>y1 on :i* ! head ( any 
,f$]al ag5cy may publi% artificial      
intellig5ce-ready biological datasets4  
7,c7 ,a report+ me*anism available to   
ea* ,f$]al ag5cy to report to !         
,director h[ ! ag5cy is comply+ ) !     
policies4  7,d7 ,a me*anism available to
 ea* ,f$]al ag5cy to reque/ assi/ance f 
! ,director reg>d+ compliance ) !       
policies4  7e7 ,public input & fe$back2 
consultation ,9 e/abli%+ ! def9itions1  
/&>ds1 res\rces1 & frameworks "u        
subsection 7a77#a7 & ! ag5cy-specific   
data managem5t policies "u subsection   
7d77#a71 ! ,director %all c>ry out !    
foll[+3 7#a7 ,solicit input & fe$back f 
! public reg>d+ ! def9itions1 /&>ds1    
res\rces1 & frameworks & !              
ag5cy-specific data managem5t policies4 
7#b7 ,consult ) ! foll[+ heads ( ,f$]al 
ag5cies t provide fund+ = qualifi$      
f$]ally fund$ rese>* to ensure su*      

ag5cies are able to comply ) !          
def9itions1 /&>ds1 res\rces1 &          
frameworks & ! ag5cy-specific data      
managem5t policies3 7,a7 ,! ,secret>y ( 
,agriculture4  7,b7 ,! ,secret>y (      
,def5se4  7,c7 ,! ,secret>y ( ,en]gy4   
7,d7 ,! ,director ( ! ,national         
,a]onautics & ,space ,adm9i/ration4     
7,e7 ,! ,director ( ! ,national         
,in/itutes ( ,heal?4  7,f7 ,!           
,adm9i/rator ( ! ,national ,sci5ce      
,f\ndation4  7,g7 ,! head ( any o!r     
,f$]al ag5cy z det]m9$ by ! ,director4  
7f7 ,advisory gr\p  7#a7 ,9 g5]al ,n    
lat] ?an #ahj days aft] ! date ( !      
enactm5t ( ?is ,act1 ! ,director %all   
e/abli% an advisory gr\p to c>ry out !  
foll[+3 7,a7 ,to provide recomm5dations 
relat+ to ! def9itions1 /&>ds1 res\rces1
 & frameworks e/abli%$ "u subsection    
7a77#a74  7,b7 ,to review & provide     
fe$back on ! ag5cy-specific data        
managem5t policies e/abli%$ or revis$ "u
 subsection 7d77#a74  7,c7 ,to provide  
recomm5dations to academic j\rnals =    

guidel9es relat+ to artificial          
intellig5ce-ready biological datasets4  
7,d7 ,to solicit recomm5dations f !     
academic community reg>d+ implem5tation 
( ! def9itions1 /&>ds1 res\rces1 &      
frameworks4  7,e7 ,to provide any o!r   
guidance ! ,director may reque/4  7#b7  
,memb]%ip  7,a7 ,9 g5]al ,! advisory    
gr\p e/abli%$ "u p>agraph 7#a7 %all be  
compos$ ( n few] ?an #ab memb]s to      
include-- 7i7 repres5tatives ( ,f$]al   
ag5cies t aw>d funds to recipi5ts to    
c>ry out qualifi$ f$]ally fund$ rese>*2 
&  7ii7 repres5tatives ( academia1      
private sector entities1 & academic     
publi%]s4  7,b7 ,t]ms  7i7 ,9 g5]al ,ea*
 memb] %all s]ve = a t]m ( #b ye>s4     
7ii7 ,r5ewal ,subject to ! discretion ( 
! ,director1 ! t]m ( ea* memb] may be   
r5ew$ = an additional #b-ye> t]m4  7#c7 
,*airp]son  7,a7 ,appo9tm5t ,!          
,*airp]son ( ! advisory gr\p %all be    
designat$ by ! ,director f among !      
memb]s4  7,b7 ,t]m ,! t]m ( ! ,*airp]son
 %all be #a ye>4  7,c7 ,r5ewal ,subject 

to ! discretion ( ! ,director1 ! t]m ( a
 ,*airp]son may be r5ew$ = an additional
 #a-ye> t]m4  7#d7 ,reports  7,a7       
,int]im report ,n lat] ?an #a ye> aft] !
 date ( ! enactm5t ( ?is ,act1 !        
advisory gr\p %all submit to ! ,director
 a int]im report t conta9s advice &     
guidance ) respect to ! matt]s describ$ 
9 p>agraph 7#a74  7,b7 ,subsequ5t       
reports ,if ! advisory gr\p or !        
,director det]m9es appropriate1 !       
advisory gr\p %all submit to ! ,director
 subsequ5t reports relat+ to ! matt]s   
describ$ 9 p>agraph 7#a74  7g7 ,f$]al   
,acquisition ,regulation revisions ,!   
,f$]al ,acquisition ,regulatory ,c\ncil 
%all revis$ ! ,f$]al ,acquisition       
,regulation z necess>y to implem5t !    
def9itions1 /&>ds1 res\rces1 &          
frameworks e/abli%$ "u subsection       
7a77#a74  7h7 ,annual report  7#a7      
,int]im report ,n lat] ?an #a ye> aft] !
 date ( ! enactm5t ( ?is ,act1 !        
,director %all submit to ,congress & !  
,comptroll] ,g5]al ( ! ,unit$ ,/ates an 

int]im report t includes in=mation      
relat+ to ! progress ( e/abli%+ !       
def9itions1 /&>ds1 res\rces1 &          
frameworks "u subsection 7a77#a7 & !    
ag5cy-specific data managem5t policies  
"u subsection 7d77#a74  7#b7 ,subsequ5t 
reports ,n lat] ?an #b ye>s aft] ! date 
( ! enactm5t ( ?is ,act1 & annually     
!reaft]1 ! ,director %all submit to     
,congress & ! ,comptroll] ,g5]al ( !    
,unit$ ,/ates a report t includes       
in=mation relat+ to ! foll[+3 7,a7 ,!   
e/abli%m5t1 implem5tation1 &1 if        
applicable1 revision1 ( ! def9itions1   
/&>ds1 res\rces1 & frameworks e/abli%$  
"u subsection 7a77#a74  7,b7 ,!         
e/abli%m5t1 implem5tation1 &1 if        
applicable1 revision ( ! ag5cy-specific 
data managem5t policies e/abli%$ or     
revis$ "u subsection 7d77#a74  7#c7     
,additional requirem5t = fir/ subsequ5t 
report ,) respect to ! fir/ subsequ5t   
report "u p>agraph 7#b71 ! ,director    
%all include a summ>y ( ! te/+ &        
evaluation "u subsection 7c7 t includes 

in=mation relat+ to ! foll[+3 7,a7 ,!   
f9d+s ( ! te/+ & evaluation4  7,b7 ,!   
mann] by :i* ! ,director address$ any   
conc]n id5tifi$ z a result ( ! te/+ &   
evaluation4  7,c7 ,an assessm5t ( any   
burd5 on recipi5ts ( fund+ = qualifi$   
f$]ally fund$ rese>* reg>d+ ensur+ t    
biological datasets are artificial      
intellig5ce-ready4  7,d7 ,a co/-b5efit  
analysis ( ! value ( ensur+ t biological
 datasets are artificial                
intellig5ce-ready 9 relation to any su* 
burd54  7i7 ,gov]nm5t ,acc\ntability    
,(fice report ,n lat] ?an #e ye>s aft] !
 date ( ! enactm5t ( ?is ,act1 !        
,comptroll] ,g5]al ( ! ,unit$ ,/ates    
%all submit to ,congress a report on !  
impact ( ! def9itions1 /&>ds1 res\rces1 
& frameworks e/abli%$ "u subsection     
7a77#a71 includ+ ! foll[+3 7#a7 ,an     
assessm5t ( ! effectiv5ess ( !          
def9itions1 /&>ds1 res\rces1 &          
frameworks 9 ensur+ ea* biological      
dataset g5]at$ by a recipi5t ( fund+ =  
qualifi$ f$]ally fund$ rese>* is        

artificial intellig5ce-ready4  7#b7 ,an 
assessm5t ( :e!r ! implem5tation ( !    
def9itions1 /&>ds1 res\rces1 &          
frameworks1 z ! case may be1 has result$
 9 an undue burd5 on any recipi5t (     
,f$]al fund+4  7#c7 ,any recomm5dations 
) respect to ! implem5tation ( !        
def9itions1 /&>ds1 res\rces1 &          
frameworks4  7j7 ,sunset ,?is section   
%all t]m9ate on ! date t is #aj ye>s    
aft] ! date ( ! enactm5t ( ?is ,act4    
7k7 ,def9itions ,9 ?is section3 7#a7    
,biological data ,! t]m biological data 
means in=mation t is measur$1 collect$1 
or aggregat$ = analysis1 includ+        
associat$ descriptors1 d]iv$ f !        
/ructure1 function1 or process ( a      
biological sy/em4  7#b7 ,biological     
dataset ,! t]m biological dataset means 
a discreet collection ( biological data4
  7#c7 ,biological data repository ,!   
t]m biological data repository means any
 c5traliz$ data /orage capacity meant = 
manag+ or /or+ biological data4  7#d7   
,negative data ,! t]m negative data     

means data t disproves1 fails to        
support1 or expla9s ?r\gh previ\sly     
unkn[n or contradictory means a rese>*  
hypo!sis b t o!rwise /ill advances      
sci5tific k or und]/&+4