,i #aai? ,,congress #a/ ,session ,h4 ,r4 #fegb ,,9 ,,! ,,h\se ,,( ,,repres5tatives ,decemb] #aj1 #bjbe,mr4 ,h>d] ( ,cali=nia 7= himself & ,mr4 ,ob]nolte7 introduc$ ! foll[+ bill2 :i* 0 ref]r$ to ! ,committee on ,en]gy & ,comm]ce ,a ,,bill ,to direct ! ,director ( ! ,national ,in/itutes ( ,heal? to c>ry out a program1 to be kn[n z ! ,x-,labs ,initiative1 to support break?r\gh biom$ical rese>* at innovative rese>* in/itutions1 & = o!r purposes4 #a4 ,%ort title ,?is ,act may be cit$ z ! ,laun*+ ,x-,labs = ,break?r\gh ,sci5ce ,act4 #b4 ,,nih in/itutional aw>ds = break?r\gh biom$ical rese>* ,"p ,a ( title ,,iv ( ! ,public ,heal? ,s]vice ,act 7#db ,u4,s4,c4 #bha et seq47 is am5d$ by add+ at ! end ! foll[+3 #djd,p4 ,,nih in/itutional aw>ds = break?r\gh biom$ical rese>* 7a7 ,9 g5]al ,! ,director ( ,,nih %all e/abli% a program1 to be kn[n z ! ,x-,labs ,initiative1 to provide long-t]m in/itutional aw>ds to eligible entities 9 accordance ) ! requirem5ts ( ?is section4 7b7 ,purposes ,! purposes ( ! program %all be-- 7#a7 to enable & catalyze innovative rese>* in/itutions to conduct break?r\gh biom$ical rese>*2 & 7#b7 to assi/ su* in/itutions 9 ! acquisition ( ,r,d plant1 z necess>y1 to complete su* rese>*4 7c7 ,in/itutional aw>ds 7#a7 ,9 g5]al ,9 c>ry+ out ! program1 ! ,director ( ,,nih %all1 act+ directly or ?r\gh ! head ( an ,,nih in/itute or c5t]1 make in/itutional aw>ds to eligible entities on a competitive basis4 7#b7 ,,xls]ies activity code ,! ,director ( ,,nih %all designate ! ,,xls]ies z a di/9ct ,,nih activity code available to all ,,nih in/itutes & c5t]s mak+ in/itutional aw>ds "u ! program4 7#c7 ,categories ,an in/itutional aw>d "u ! program %all be made )9 "o ( ! foll[+ categories3 7,a7 ,,xl#ja fund+ ,aw>ds ( ,,xl#ja fund+ to support basic sci5ce rese>* in/itutions ^: pr9cipal activities1 or propos$ pr9cipal activities1 are direct$ t[>d advanc+ f\ndational sci5tific discov]y4 ,! purpose ( su* aw>ds %all be to provide su* in/itutions /able1 long-t]m fund+ & m9imal budget>y reprogramm+ requirem5ts4 7,b7 ,,xl#jb fund+ ,aw>ds ( ,,xl#jb fund+ to support sci5ce in/itutions ^: pr9cipal activities1 or propos$ pr9cipal activities1 are direct$ t[>d develop+ new sci5tific res\rces1 includ+ datasets or measurem5t tools or te*niques1 ) deliv]ables t are cle>ly def9$ at ! beg9n+ ( ! aw>d4 7,c7 ,,xl#jc fund+ ,aw>ds ( ,,xl#jc fund+ to support nonpr(it in/itutions t aw>d focus$ rese>* organizations1 individual rese>*]s1 or rese>* collaborations or c5t]s funds to conduct break?r\gh biom$ical rese>*4 7,d7 ,,xl#jd fund+ ,aw>ds ( ,,xl#jd fund+ to support ! =mation & plann+ ( new sci5tific in/itutions t w be eligible = ,,xl#ja1 ,,xl#jb1 or ,,xl#jc fund+4 7#d7 ,special rules applicable to ,,xl#jc fund+ 7,a7 ,regrants ,an eligible entity t receives an aw>d ( ,,xl#jc fund+ describ$ 9 p>agraph 7#c77;,c7 %all1 subject to ! t]ms ( ! aw>d1 make regrants us+ funds f ! aw>d to support rese>* teams1 e>ly-/age projects1 or innovative sci5tific initiatives consi/5t ) ! purposes ( ?is section4 ,su* teams1 projects1 & initiatives %all be locat$ 9 ! ,unit$ ,/ates4 7,b7 ,requirem5ts ,an eligible entity t receives an aw>d ( ,,xl#jc fund+ describ$ 9 p>agraph 7#c77;,c7-- 7i7 %all use su* fund+ to provide assi/ance1 ?r\gh regrants describ$ 9 subp>agraph 7,a71 to organizations 79 ?is section ref]r$ to z regrant recipi5ts7 t ! eligible entity det]m9es are unlikely to receive support ?r\gh traditional ,,nih grants despite ! break?r\gh pot5tial ( ! rese>* to be conduct$ by ! regrant recipi5t2 7ii7 %all use innovative me?ods to id5tify1 fund1 & evaluate ! rese>* to be conduct$ us+ su* assi/ance2 & 7iii7 n lat] ?an "o ye> aft] ! date on :i* ! eligible entity provides su* assi/ance to a regrant recipi5t1 %all make available to ! public a summ>y ( ! me?od by :i* ! eligible entity id5tifi$1 fund$1 & plans to evaluate ! regrant recipi5t4 7#e7 ,am\nts 7,a7 ,,xl#ja1 ,,xl#jb1 & ,,xl#jc fund+ 7i7 ,9 g5]al ,! ,director ( ,,nih %all /ructure an aw>d ( ,,xl#ja1 ,,xl#jb1 or ,,xl#jc fund+ su* t ! aw>d totals n less ?an #e1jjj1jjj & n m ?an #ej1jjj1jjj p] fiscal ye> = a p]iod ( #g consecutive fiscal ye>s4 ,! am\nt ( su* an aw>d %all be det]m9$ bas$ on in/itutional scope1 sci5tific ambition1 & programmatic ne$s4 7ii7 ,r5ewals ,! ,director ( ,,nih may r5ew an aw>d describ$ 9 clause 7i7 = n m ?an "o additional p]iod ( #g consecutive fiscal ye>s1 subject to-- 7,i7 a competitive review ( in/itutional p]=mance & sci5tific impact ov] ! previ\s p]iod2 7,,ii7 ! availability ( appropriations2 & 7,,iii7 a programmatic cap on ! proportion ( in/itutional aw>ds eligible = r5ewal1 to be det]m9$ by ! ,director ( ,,nih1 to ensure regul> entry ( new in/itutions into ! program4 7,b7 ,,xl#jd fund+ 7i7 ,9 g5]al ,! ,director ( ,,nih %all /ructure an aw>d ( ,,xl#jd fund+ su* t ! aw>d totals n less ?an #a1jjj1jjj & n m ?an #e1jjj1jjj p] fiscal ye> = a p]iod ( #a1 #b1 or #c consecutive fiscal ye>s1 z det]m9$ by ! ,director ( ,,nih4 7ii7 ,prohibition on r5ewals ,! ,director ( ,,nih may n r5ew an aw>d describ$ 9 clause 7i74 7#f7 ,applications ,an eligible entity seek+ an aw>d "u ! program %all submit to ! ,director ( ,,nih an application at su* "t1 9 su* =m1 & conta9+ su* in=mation z ! ,director ( ,,nih may require4 7#g7 ,ma9ta9+ eligibility ,to rema9 eligible = an in/itutional aw>d "u ! program & rema9 9 good /&+ ) respect to an aw>d1 an eligible entity %all n compete = or receive any o!r ,f$]al rese>* fund+ 9 ! =m ( a rese>* grant1 exclud+ a tra9+ grant1 dur+ ! aw>d p]iod ( ! entity = ,,xl#ja1 ,,xl#jb1 or ,,xl#jc fund+4 7#h7 ,e>ly t]m9ation or susp5sion 7,a7 ,9 g5]al ,! ,director ( ,,nih may t]m9ate or susp5d an aw>d made to an aw>d recipi5t "u ?is section prior to ! expiration ( ! applicable p]iod ( ! aw>d describ$ 9 p>agraph 7#e7 if ! ,director det]m9es t ! aw>d recipi5t-- 7i7 is n meet+ ! deliv]ables ref]r$ to 9 p>agraph 7#c77;,b71 if applicable2 7ii7 is no long] an eligible entity2 or 7iii7 is o!rwise fail+ to comply ) ! t]ms & conditions ( ! aw>d4 7,b7 ,revocation ( funds2 reallocation ,^u a det]m9ation to t]m9ate or susp5d an aw>d "u subp>agraph 7,a71 ! ,director ( ,,nih may revoke any rema9+ funds f ! aw>d & reallocate su* funds to new aw>ds "u ?is section4 7d7 ,adm9i/ration 7#a7 ,9 g5]al ,! program %all be adm9i/]$ by ! ,director ( ,,nih1 9 coord9ation ) ! heads ( relevant in/itutes & c5t]s4 7#b7 ,in/itute p>ticipation ,any in/itute or c5t] )9 ! ,national ,in/itutes ( ,heal? may utilize ! program to fund in/itutions )9 _! areas ( sci5tific focus1 subject to coord9ation ) ! ,director ( ,,nih & ! availability ( funds4 7#c7 ,o!r transactions au?orities ,not)/&+ any o!r provision ( law1 ! ,director ( ,,nih may use ! au?orities available "u section #djb7n77#a7 or o!r applicable transactions au?orities to c>ry out ?is section4 7e7 ,report+ requirem5ts 7#a7 ,initial reports ,n lat] ?an #a ye> aft] ! date ( enactm5t ( ?is ,act1 & annually !reaft] = #b additional ye>s1 ! ,director ( ,,nih %all submit to ! appropriate committees ( ,congress a report describ+-- 7,a7 ! progress made 9 e/abli%+ ! program1 includ+ ! developm5t ( application processes1 review crit]ia1 & aw>d categories2 7,b7 ! numb] & types ( applications receiv$ "u ! program2 7,c7 ! numb]1 type1 & am\nt ( aw>ds made "u ! program2 & 7,d7 any *all5ges or b>ri]s enc\nt]$ 9 ! implem5tation ( ! program4 7#b7 ,p]iodic evaluation ,n lat] ?an #e ye>s aft] ! date ( ! fir/ aw>d "u ! program1 & once e #e ye>s !reaft] dur+ ! t]m ( ! program1 ! ,director ( ,,nih %all submit to ! appropriate committees ( ,congress a report evaluat+-- 7,a7 ! sci5tific impact & outcomes ( in/itutions receiv+ support "u ! program2 7,b7 ! effectiv5ess ( ! program 9 advanc+ ! purposes describ$ 9 subsection 7b72 7,c7 lessons le>n$ f implem5tation ( ! program & recomm5dations = program improvem5t2 & 7,d7 ! ext5t to :i* ! program has r$uc$ adm9i/rative burd5 & enabl$ rese>* t is high-risk & high-rew>d4 7f7 ,def9itions ,9 ?is section3 7#a7 ,appropriate committees ( ,congress ,! t]m appropriate committees ( ,congress means-- 7,a7 ! ,committee on ,en]gy & ,comm]ce & ! ,committee on ,appropriations ( ! ,h\se ( ,repres5tatives2 & 7,b7 ! ,committee on ,heal?1 ,education1 ,labor1 & ,p5sions & ! ,committee on ,appropriations ( ! ,s5ate4 7#b7 ,basic sci5ce rese>* in/itution ,! t]m basic sci5ce rese>* in/itution means a rese>* in/itution conduct+ sy/ematic /udy direct$ t[>d great] und]/&+ ( fundam5tal pr9ciples or ph5om5a ( nature )\t specific applications 9 m9d4 7#c7 ,break?r\gh biom$ical rese>* ,! t]m break?r\gh biom$ical rese>* means sci5tific rese>* t has ! pot5tial to create sub/antial1 field-def9+ advances 9 k1 me?ods1 or te*nologies t enable significant improvem5ts 9 human heal? or sci5tific capability4 7#d7 ,eligible entity ,! t]m eligible entity means-- 7,a7 a nonpr(it rese>* organization2 7,b7 an in/itution ( high] education1 z def9$ 9 section #aja ( ! ,high] ,education ,act ( #aife2 7,c7 a =-pr(it entity ) nonpr(it subsidi>ies d$icat$ to sci5tific rese>*2 7,d7 an individual ) plans to e/abli% a nonpr(it rese>* organization2 or 7,e7 any o!r rese>* organization t ! ,director ( ,,nih det]m9es appropriate4 7#e7 ,focus$ rese>* organization ,! t]m focus$ rese>* organization means a "t-limit$1 goal-ori5t$ nonpr(it entity t conc5trates res\rces & tal5t on a*iev+ a def9$ sci5tific or te*nological objective n suffici5tly pursu$ )9 exi/+ academic1 corporate1 or gov]nm5t /ructures4 7#f7 ,f\ndational sci5tific discov]y ,! t]m f\ndational sci5tific discov]y means rese>* t produces broadly enabl+ sci5tific k1 me?ods1 or tools t support subsequ5t appli$ or translational advances4 7#g7 ,in/itutional aw>d2 aw>d ,! t]m in/itutional aw>d or aw>d means an aw>d ( fund+ made "u ! program4 7#h7 ,in/itutional scope ,! t]m in/itutional scope means ! size & organizational capacity ( an in/itution to und]take rese>* activities1 includ+ ! bread? ( its sci5tific rese>*1 numb] ( p]sonnel support$1 & physical rese>* infra/ructure relevant to ! propos$ aw>d4 7#i7 ,,nih ,! t]m ,,nih means ! ,national ,in/itutes ( ,heal?4 7#aj7 ,nonpr(it rese>* organization ,! t]m nonpr(it rese>* organization means a dome/ic public or private organization exempt f taxation "u section #eja7;c77#c7 ( ! ,int]nal ,rev5ue ,code ( #aihf t conducts or supports sci5tific rese>* z a prim>y purpose4 7#aa7 ,program ,! t]m program means ! program au?oriz$ "u subsection 7a74 7#ab7 ,programmatic ne$s ,! t]m programmatic ne$s means ! degree to :i* an aw>d w\ld advance ! /rategic rese>* priorities & unmet ne$s ( ,,nih & its in/itutes & c5t]s1 z det]m9$ by ! ,director ( ,,nih4 7#ac7 ,r,d plant ,! t]m ,r,d plant means fix$ assets us$ prim>ily = rese>* & developm5t1 includ+ ! con/ruction1 expansion1 leas+1 or mod]nization ( rese>* facilities & ! acquisition ( major movable rese>* equipm5t4 7#ad7 ,regrant ,! t]m regrant means ! provision ( a subaw>d or o!r f9ancial assi/ance by an aw>d recipi5t "u ! program to c>ry out rese>* activities consi/5t ) ! purposes ( ! orig9al aw>d4 7#ae7 ,sci5tific ambition ,! t]m sci5tific ambition means ! scale1 novelty1 & trans=mative pot5tial ( an in/itution's propos$ rese>* ag5da "u an aw>d1 z measur$ by ! significance ( ! sci5tific que/ions address$ & ! pot5tial to advance fundam5tal or translational und]/&+4 7#af7 ,unit$ ,/ates ,! t]m ,unit$ ,/ates means ! ,/ates & ! ,di/rict ( ,columbia4 7g7 ,au?orization ( appropriations ,!re is au?oriz$ to be appropriat$ to c>ry out ?is section su* sums z may be necess>y = ea* ( fiscal ye>s #bjbf ?r\gh #bjca4 4