,,ii #aah? ,,congress #b;d ,session ,s4 #dffg ,,9 ,,! ,,s5ate ,,( ,,! ,,unit$ ,,/ates ,july #aj1 #bjbd,mr4 ,paul introduc$ ! foll[+ bill2 :i* 0 read twice & ref]r$ to ! ,committee on ,homel& ,security & ,gov]nm5tal ,affairs ,a ,,bill ,to am5d title #ca1 ,unit$ ,/ates ,code1 to e/abli% ! ,life ,sci5ces ,rese>* ,security ,bo>d1 & = o!r purposes4 #a4 ,%ort title ,?is ,act may be cit$ z ! ,risky ,rese>* ,review ,act4 #b4 ,life ,sci5ces ,rese>* ,security ,bo>d 7a7 ,9 g5]al ,subtitle ,v ( title #ca1 ,unit$ ,/ates ,code1 is am5d$ by add+ at ! end ! foll[+3 #gi ,life ,sci5ces ,rese>* ,security ,bo>d #gija4 ,def9itions ,9 ?is *apt]3 7#a7 ,ag5cy ,! t]m ag5cy has ! mean+ giv5 ! t]m 9 section #eeb7;f7 ( title #e4 7#b7 ,appropriate congressional committees ,! t]m appropriate congressional committees means ! ,committee on ,homel& ,security & ,gov]nm5tal ,affairs ( ! ,s5ate & ! ,committee on ,ov]sight & ,acc\ntability ( ! ,h\se ( ,repres5tatives4 7#c7 ,bo>d ,! t]m ,bo>d means ! ,life ,sci5ces ,rese>* ,security ,bo>d e/abli%$ "u section #gijb7;a74 7#d7 ,dual use ,! t]m dual use1 ) respect to rese>*1 means rese>* t1 bas$ on curr5t und]/&+ z ( ! date ( rese>*1 c be reasonably anticipat$ to provide k1 in=mation1 products1 or te*nologies t c\ld directly or ) only m9or modification be misappli$ to pose a significant ?reat ) broad pot5tial consequ5ces to public heal? & safety1 agricultural crops or o!r plants1 animals1 mat]iel1 or national security4 7#e7 ,employee 7,a7 ,9 g5]al ,! t]m employee-- 7i7 means an employee ( an ag5cy2 & 7ii7 includes an individual1 o!r ?an an employee ( an ag5cy1 work+ "u a contract ) an ag5cy4 7,b7 ,rule ( con/ruction ,) respect to an individual describ$ 9 subp>agraph 7,a77ii71 solely = ! purposes ( ?is *apt]1 ! ag5cy t has ent]$ into ! contract "u :i* ! employee is work+ %all be con/ru$ to be ! ag5cy employ+ ! employee4 7#f7 ,f$]al fund+ ,! t]m ,f$]al fund+-- 7,a7 means am\nts aw>d$ by an ag5cy pursuant to a grant1 coop]ative agreem5t1 int]ag5cy agreem5t1 contract1 or o!r in/rum5t2 & 7,b7 includes-- 7i7 an 9-k9d contribution by an ag5cy us$ = life sci5ces rese>* purposes2 & 7ii7 rese>* conduct$ by an ag5cy to :i* funds 7 appropriat$ = conduct+ rese>*4 7#g7 ,ga9 ( function rese>* ,! t]m ga9 ( function rese>* means rese>* t has ! pot5tial to enhance ! transmissibility or virul5ce ( a pot5tial p&emic pa?og54 7#h7 ,high-risk life sci5ces rese>* ,! t]m high-risk life sci5ces rese>*-- 7,a7 means life sci5ces rese>* t-- 7i7 has a pot5tial dual use nature2 or 7ii7 c\ld pose a ?reat to public heal?1 safety1 or national security2 & 7,b7 includes-- 7i7 ga9 ( function rese>*2 7ii7 rese>* involv+ a pot5tial p&emic pa?og51 includ+ g5etic modification ( a pot5tial p&emic pa?og5 & ! syn!tic creation ( a pot5tial p&emic pa?og52 & 7iii7 an activity involv+ ! collection or surveillance ( a pot5tial p&emic pa?og54 7#i7 ,life sci5ces rese>* ,! t]m life sci5ces rese>* means rese>* 9 agricultural biote*nology1 biog5]ics1 bio9=matics1 biom$ical eng9e]+1 bioph>maceuticals1 academic m$ical c5t]s1 biote*nology1 *emical syn!sis1 *emi/ry te*nology1 m$ical diagno/ics1 g5omics1 m$ical image analysis1 m>9e biology1 m$ical devices1 m$ical nanote*nology1 natural product ph>maceuticals proteomics1 reg5]ative m$ic9e1 ,,rna int]f]5ce1 /em cell rese>*1 m$ical & neurological cl9ical trials1 heal? robotics1 & vet]9>y sci5ce4 7#aj7 ,pot5tial p&emic pa?og5 ,! t]m pot5tial p&emic pa?og5-- 7,a7 means a virus1 natural or syn!tic1 bact]ia1 fungus1 prion1 or euk>yotic p>asite1 or any /ra9 or v>iant ( a virus1 bact]ium1 fungus1 prion1 or euk>yotic p>asite-- 7i7 t-- 7,i7 is reasonably anticipat$ to be mod]ately or highly transmissible & likely capable ( wide & uncontrollable spread 9 human populations2 & 7,,ii7 is describ$ 9 clause 7ii7 or 7iii72 & 7ii7 reasonably anticipat$ to be ( l[1 mod]ate1 or high virul5ce & likely to cause significant morbidity or mortality 9 humans2 or 7iii7 reasonably anticipat$ to pose a sev]e ?reat to public heal?1 ! capacity ( public heal? sy/ems to function1 or national security if all[$ to spread )9 ! g5]al population2 & 7,b7 includes-- 7i7 subject to subp>agraph 7,c71 influ5za viruses2 7ii7 s>becoviruses2 7iii7 m]becoviruses2 7iv7 h5ipaviruses1 includ+ ,nipah virus2 7v7 filoviruses2 7vi7 ar5aviruses2 7vii7 or?opoxviruses2 7viii7 ,y]s9ia pe/is2 7ix7 any syn!tic con/ruct ( su* viruses2 & 7x7 a select ag5t or tox91 "w ) :i* poses a significant risk ( delib]ate misuse2 & 7,c7 does n include seasonal influ5za viruses1 unless su* viruses h be5 manipulat$ to include g5etic sequ5ces f a pot5tial p&emic pa?og54 7#aa7 ,select ag5t or tox9 ,! t]m select ag5t or tox9 means an ag5t or tox9 id5tifi$ "u-- 7,a7 section #gc4c7;b7 ( title #db1 ,code ( ,f$]al ,regulations1 z 9 effect on ! date ( enactm5t ( ! ,risky ,rese>* ,review ,act2 7,b7 section #cca4c7;b7 ( title #g1 ,code ( ,f$]al ,regulations1 z 9 effect on ! date ( enactm5t ( ! ,risky ,rese>* ,review ,act2 or 7,c7 section #aba4c7;b7 ( title #i1 ,code ( ,f$]al ,regulations1 z 9 effect on ! date ( enactm5t ( ! ,risky ,rese>* ,review ,act4 #gijb4 ,e/abli%m5t & memb]%ip 7a7 ,e/abli%m5t ,!re is e/abli%$ z an indep5d5t ag5cy )9 ! ,executive ,bran* a bo>d to be kn[n z ! ,life ,sci5ces ,rese>* ,security ,bo>d to review propos$ ,f$]al fund+ = life sci5ces rese>* 9 accordance ) section #gijf4 7b7 ,appo9tm5t ( memb]s 7#a7 ,9 g5]al ,! ,presid5t1 by & ) ! advice & cons5t ( ! ,s5ate1 %all appo9t1 )\t reg>d to political affiliation1 #i individuals :o are citiz5s ( ! ,unit$ ,/ates to s]ve z memb]s ( ! ,bo>d = n m ?an #b t]ms ( #d ye>s ea*1 includ+-- 7,a7 ! ,executive ,director appo9t$ "u section #gijc7;a72 7,b7 #e nongov]nm5tal sci5ti/s 9 a life sci5ces field2 & 7,c7 #b nongov]nm5tal national security exp]ts4 7#b7 ,p]iod = nom9ations ,! ,presid5t %all make nom9ations to ! ,bo>d n lat] ?an #cj days aft] ! date ( enactm5t ( ?is *apt]4 ,if ! ,s5ate votes n to confirm a nom9ation to ! ,bo>d1 ! ,presid5t %all make an additional nom9ation n lat] ?an #aj days aft] su* vote by ! ,s5ate4 7#c7 ,consid]ations ( recomm5dations ,! ,presid5t %all make nom9ations to ! ,bo>d aft] consid]+ individuals recomm5d$ by ! ,*air & ,rank+ ,memb] ( ! appropriate congressional committees4 7#d7 ,qualifications ,individuals nom9at$ to ! ,bo>d-- 7,a7 %all-- 7i7 be imp>tial individuals2 & 7ii7 be di/+ui%$ individuals ( high national pr(essional reputation 9 _! respective fields :o are capable ( ex]cis+ ! indep5d5t & objective judgm5t necess>y to conduct an imp>tial assessm5t ( ! pot5tial risks & b5efits associat$ ) ,f$]al fund+ ( life sci5ces rese>* to public heal? & national security2 & 7,b7 may n be an employee ( ! ,f$]al ,gov]nm5t on ! date ( ! appo9tm5t or dur+ ! #c-ye> p]iod prec$+ ! date ( ! appo9tm5t4 7#e7 ,limitations ,n m ?an #d concurr5t memb]s ( ! ,bo>d may be employ$ by1 a subcontractor (1 a previ\s employee (1 or a previ\s subcontractor (-- 7,a7 ! ,dep>tm5t ( ,def5se2 7,b7 ! ,dep>tm5t ( ,homel& ,security2 7,c7 ! ,national ,in/itute ( ,all]gy & ,infecti\s ,diseases ( ! ,dep>tm5t ( ,heal? & ,human ,s]vices2 7,d7 ! ,(fice ( ! ,director ( ,national ,intellig5ce2 or 7,e7 ! ,dep>tm5t ( ,en]gy4 7#f7 ,consid]ation by ! ,s5ate 7,a7 ,9 g5]al ,nom9ations = appo9tm5t to ! ,bo>d %all be ref]r$ to ! ,committee on ,homel& ,security & ,gov]nm5tal ,affairs ( ! ,s5ate = consid]ation4 7,b7 ,r5om9ation ,a memb] ( ! ,bo>d :o is recomm5d$ to s]ve a second t]m %all be nom9at$ = appo9tm5t to ! ,bo>d1 & su* nom9ation %all be ref]r$ pursuant to subp>agraph 7,a74 7#g7 ,vacancy ,n lat] ?an #cj days aft] ! date on :i* a vacancy on ! ,bo>d occurs1 ! vacancy %all be fill$ 9 ! same mann] z specifi$ = ! orig9al appo9tm5t4 7#h7 ,removal 7,a7 ,9 g5]al ,no memb] ( ! ,bo>d %all be remov$ f (fice1 o!r ?an by-- 7i7 impea*m5t & conviction2 7ii7 ! action ( ! ,presid5t = ineffici5cy1 neglect ( duty1 malfeasance 9 (fice1 physical disability1 m5tal incapacity1 or any o!r condition t sub/antially impairs ! p]=mance ( ! memb]'s duties2 or 7iii7 ! ,bo>d 9 accordance ) subp>agraph 7,b74 7,b7 ,action by ,bo>d ,if ! ,director ( ! ,(fice ( ,gov]nm5t ,e?ics det]m9es t p>ticipation by a memb] ( ! ,bo>d 9 high-risk life sci5ces rese>* con/itutes a conflict ( int]e/1 ! ,bo>d %all take /eps to mitigate or manage ! conflict1 :i* may include removal4 7,c7 ,notice ( removal by ,presid5t 7i7 ,9 g5]al ,9 ! case ( ! removal ( a memb] ( ! ,bo>d by ! ,presid5t z describ$ 9 subp>agraph 7,a77ii71 n lat] ?an #aj days aft] ! removal1 ! ,presid5t %all submit to ! ,*air & ,rank+ ,memb]s ( ! appropriate congressional committees a report specify+ ! facts f\nd & ! gr\nds = removal4 7ii7 ,publication ( report ,! ,presid5t %all publi% 9 ! ,f$]al ,regi/] ea* report submitt$ "u clause 7i71 except t ! ,presid5t may1 if necess>y to protect ! rights ( a p]son nam$ 9 ! report or to prev5t undue int]f]5ce ) any p5d+ prosecution1 po/pone or refra9 f publicly publi%+ any or all ( ! report until ! completion ( su* p5d+ cases or pursuant to privacy protection requirem5ts 9 law4 7c7 ,m&atory conflicts ( int]e/ review 7#a7 ,9 g5]al ,! ,director ( ! ,(fice ( ,gov]nm5t ,e?ics %all-- 7,a7 n lat] ?an #ahj days aft] ! date ( ! enactm5t ( ?is *apt]1 & ^u an appo9tm5t ( a memb] to ! ,bo>d "u subsection 7a77#a7 !reaft]1 conduct a review ( ea* individual nom9at$ & appo9t$ to ! ,bo>d to ensure su* individual does n h any conflict ( int]e/2 & 7,b7 p]iodically !reaft]1 conduct a review ( ea* individual nom9at$ & appo9t$ to ! ,bo>d to ensure ! individual does n h any conflict ( int]e/ dur+ ! t]m ( s]vice ( ! individual4 7#b7 ,notification 7,a7 ,9 g5]al ,n lat] ?an #c days aft] ! date on :i* ! ,director ( ! ,(fice ( ,gov]nm5t ,e?ics becomes aw>e t a memb] ( ! ,bo>d possesses a pot5tial conflict ( int]e/ to ! mission ( ! ,bo>d1 ! ,director %all notify ! ,*air & ,rank+ ,memb]s ( ! appropriate congressional committees ( ! pot5tial conflict ( int]e/4 7,b7 ,notification by memb] ,n lat] ?an #cj days aft] ! date on :i* a memb] ( ! ,bo>d becomes aw>e t ano!r memb] ( ! ,bo>d possesses a pot5tial conflict ( int]e/ to ! mission ( ! ,bo>d1 ! memb] ( ! ,bo>d or ! ,executive ,director ( ! ,bo>d %all notify ! ,*air & ,rank+ ,memb]s ( ! appropriate congressional committees ( ! pot5tial conflict ( int]e/4 7d7 ,security cle>ances ,all memb]s ( ! ,bo>d %all be grant$ all ! necess>y security cle>ances & accesses1 includ+ to relevant ,presid5tial & dep>tm5t or ag5cy special access & comp>tm5t$ access programs1 9 an accel]at$ mann] subject to ! /&>d proc$ures = grant+ su* cle>ances4 ,all nom9ees = appo9tm5t to ! ,bo>d %all qualify = ! necess>y security cle>ances & accesses prior to be+ consid]$ = confirmation by ! ,committee on ,homel& ,security & ,gov]nm5tal ,affairs ( ! ,s5ate4 7e7 ,p>ticipation 9 high-,risk life sci5ces rese>* 7#a7 ,disclosure requir$ ,a memb] ( ! ,bo>d %all disclose :e!r ! memb] has p>ticipat$ 9 or is curr5tly p>ticipat+ 9 high-risk life sci5ces rese>*4 7#b7 ,conflicts ( int]e/ 7,a7 ,9 g5]al ,! p>ticipation 9 high-risk life sci5ces rese>* by a memb] ( ! ,bo>d-- 7i7 %all be consid]$ a pot5tial conflict ( int]e/2 & 7ii7 %all be subject to scrut9y by ! ,director ( ! ,(fice ( ,gov]nm5t ,e?ics4 7,b7 ,det]m9ation ,if ! ,director ( ! ,(fice ( ,gov]nm5t ,e?ics det]m9es t p>ticipation by a memb] ( ! ,bo>d 9 high-risk life sci5ces rese>* con/itutes a conflict ( int]e/1 ! ,bo>d %all take /eps to mitigate or manage ! conflict1 :i* may include-- 7i7 ! recusal ( ! affect$ memb] f relevant discussions & det]m9ations2 & 7ii7 removal ( ! affect$ memb] f ! ,bo>d4 7f7 ,comp5sation ( memb]s 7#a7 ,9 g5]al ,subject to su* rules z may be adopt$ by ! ,bo>d1 )\t reg>d to ! provisions ( title #e gov]n+ appo9tm5ts 9 ! competitive s]vice & )\t reg>d to ! provisions ( *apt] #ea & sub*apt] ,,iii ( *apt] #ec ( t title relat+ to classification & ,g5]al ,s*$ule pay rates1 a memb] ( ! ,bo>d1 o!r ?an ! ,executive ,director1 %all be comp5sat$ at a rate-- 7,a7 propos$ by ! ,executive ,director & approv$ by ! ,bo>d2 7,b7 n to exce$ ! rate ( basic pay = level ,,ii ( ! ,executive ,s*$ule2 & 7,c7 t is comm5surate )-- 7i7 ! "t a memb] ( ! ,bo>d sp5ds engag$ 9 ! p]=mance ( duties on ! ,bo>d2 & 7ii7 necess>y travel+ exp5ses4 7#b7 ,outside employm5t ,subject to t]ms & approval det]m9$ by ! ,director ( ! ,(fice ( ,gov]nm5t ,e?ics1 a memb] ( ! ,bo>d may ma9ta9 outside employm5t & affiliations :ile s]v+ on ! ,bo>d4 7g7 ,ov]sight 7#a7 ,s5ate ,! ,committee on ,homel& ,security & ,gov]nm5tal ,affairs ( ! ,s5ate %all-- 7,a7 h cont9u+ legislative ov]sight jurisdiction 9 ! ,s5ate ) respect to ! (ficial conduct ( ! ,bo>d & ag5cy compliance ) requirem5ts issu$ by ! ,bo>d2 & 7,b7 h access to any records provid$ to or creat$ by ! ,bo>d4 7#b7 ,h\se ( ,repres5tatives ,! ,committee on ,ov]sight & ,acc\ntability ( ! ,h\se ( ,repres5tatives %all-- 7,a7 h cont9u+ legislative ov]sight jurisdiction 9 ! ,h\se ( ,repres5tatives ) respect to ! (ficial conduct ( ! ,bo>d & ag5cy compliance ) requirem5ts issu$ by ! ,bo>d2 & 7,b7 h access to any records provid$ to or creat$ by ! ,bo>d4 7#c7 ,duty to coop]ate ,! ,bo>d %all h ! duty to coop]ate ) ! ex]cise ( ov]sight jurisdiction describ$ 9 ?is subsection4 7#d7 ,security cle>ances ,! ,*air & ,rank+ ,memb]s ( ! appropriate congressional committees1 & designat$ committee /aff1 %all be grant$ all security cle>ances & accesses held by ! ,bo>d1 includ+ to relevant ,presid5tial & dep>tm5t or ag5cy special access & comp>tm5t$ access programs4 7h7 ,(fice space ,9 select+ (fice space = ! ,bo>d1 ! ,bo>d %all exhau/ options = unus$ (fice spaces own$ by ! ,f$]al ,gov]nm5t z ( ! date ( enactm5t ( ?is *apt]4 #gijc4 ,bo>d p]sonnel 7a7 ,executive director 7#a7 ,appo9tm5t ,n lat] ?an #de days aft] ! date ( ! enactm5t ( ?is *apt]1 ! ,presid5t %all appo9t #a individual :o is a citiz5 ( ! ,unit$ ,/ates1 )\t reg>d to political affiliation1 to ! position ( ,executive ,director ( ! ,bo>d = a t]m ( #d ye>s4 7#b7 ,qualifications ,! individual appo9t$ z ,executive ,director "u p>agraph 7#a7 %all be a private individual ( integrity & imp>tiality :o-- 7,a7 is a di/+ui%$ sci5ti/ 9 a life sci5ces field2 & 7,b7 is n1 & has n be5 = ! #c-ye> p]iod prec$+ ! date ( ! appo9tm5t-- 7i7 an employee ( ! ,f$]al ,gov]nm5t2 or 7ii7 a p>ticipant 9 high-risk life sci5ces rese>* support$ by ,f$]al fund+4 7#c7 ,security cle>ances 7,a7 ,9 g5]al ,a c&idate = ,executive ,director %all be grant$ all security cle>ances & accesses held by ! ,bo>d1 includ+ to relevant ,presid5tial & dep>tm5t or ag5cy special access & comp>tm5t$ access programs 9 an accel]at$ mann]1 subject to ! /&>d proc$ures = grant+ su* cle>ances4 7,b7 ,qualification prior to appo9tm5t ,! ,presid5t %all ensure t a c&idate = ,executive ,director qualifies = ! security cle>ances & accesses describ$ 9 subp>agraph 7,a7 prior to appo9tm5t4 7#d7 ,functions ,! ,executive ,director %all-- 7,a7 s]ve z pr9cipal liaison to ,congress & ag5cies2 7,b7 s]ve z ,*air ( ! ,bo>d2 7,c7 be responsible = ! adm9i/ration & coord9ation ( ! responsibilities ( ! ,bo>d2 & 7,d7 be responsible = ! adm9i/ration ( all (ficial activities conduct$ by ! ,bo>d4 7#e7 ,removal ,not)/&+ section #gijb7;b77#h71 ! ,executive ,director %all n be remov$ = reasons o!r ?an = cause on ! gr\nds ( ineffici5cy1 neglect ( duty1 malfeasance 9 (fice1 physical disability1 m5tal incapacity1 or any o!r condition t sub/antially impairs ! p]=mance ( ! responsibilities ( ! ,executive ,director or ! /aff ( ! ,bo>d4 7#f7 ,t]ms ,an ,executive ,director %all n s]ve m ?an #b t]ms4 7b7 ,/aff 7#a7 ,9 g5]al ,! ,bo>d1 )\t reg>d to ! civil s]vice laws1 may appo9t additional p]sonnel z necess>y to enable ! ,bo>d & ! ,executive ,director to p]=m ! duties ( ! ,bo>d4 7#b7 ,qualifications ,ea* individual appo9t$ to ! /aff ( ! ,bo>d-- 7,a7 %all be a citiz5 ( ! ,unit$ ,/ates ( integrity & imp>tiality2 7,b7 %all h exp]tise 9 ! life sci5ces field or ! national security field2 & 7,c7 may n be a p>ticipant 9 any f$]ally fund$ rese>* activity on ! date ( ! appo9tm5t or dur+ ! c\rse ( s]vice ( ! individual on ! ,bo>d4 7#c7 ,security cle>ances 7,a7 ,9 g5]al ,a c&idate = appo9tm5t to ! /aff ( ! ,bo>d %all be grant$ all security cle>ances & accesses held by ! ,bo>d1 includ+ to relevant ,presid5tial & dep>tm5t or ag5cy special access & comp>tm5t$ access programs1 9 an accel]at$ mann]1 subject to ! /&>d proc$ures = grant+ su* cle>ances4 7,b7 ,conditional employm5t 7i7 ,9 g5]al ,! ,bo>d may (f] conditional employm5t to a c&idate = a /aff position ( ! ,bo>d p5d+ ! completion ( security cle>ance backgr\nd inve/igations4 ,dur+ ! p5d5cy ( su* inve/igations1 ! ,bo>d %all ensure t any su* employee does n h access to1 or responsibility involv+1 classifi$ or o!rwise re/rict$ mat]ials4 7ii7 ,unqualifi$ /aff ,if an individual hir$ on a conditional basis "u clause 7i7 is d5i$ or o!rwise does n qualify = all security cle>ances necess>y to c>ry out ! responsibilities ( ! position = :i* conditional employm5t has be5 (f]$1 ! ,bo>d %all imm$iately t]m9ate ! individual's employm5t4 7#d7 ,support f ag5cies 7,a7 ,9 g5]al ,! head ( ea* ag5cy %all designate n less ?an #a full-"t employee ( ! ag5cy z ! repres5tative ( ! ag5cy to-- 7i7 provide te*nical assi/ance to ! ,bo>d2 & 7ii7 support ! review process ( ! ,bo>d ) respect to ! ag5cy "u section #gijf 9 a non-vot+ /aff capacity4 7,b7 ,prohibition ,a repres5tative designat$ "u subp>agraph 7,a7 & any employee ( an ag5cy may n directly or indirectly influ5ce 9 any capacity a det]m9ation by ! ,bo>d "u section #gijf ) respect to life sci5ces rese>* fund$ by ! ag5cy4 7c7 ,comp5sation ,subject to su* rules z may be adopt$ by ! ,bo>d1 )\t reg>d to ! provisions ( title #e gov]n+ appo9tm5ts 9 ! competitive s]vice & )\t reg>d to ! provisions ( *apt] #ea & sub*apt] ,,iii ( *apt] #ec ( t title relat+ to classification & ,g5]al ,s*$ule pay rates1 ! ,executive ,director %all-- 7#a7 be comp5sat$ at a rate n to exce$ ! rate ( basic pay = level ,,ii ( ! ,executive ,s*$ule2 7#b7 s]ve ! entire t5ure z ,executive ,director z "o full-"t employee2 & 7#c7 appo9t & fix ! comp5sation ( su* o!r p]sonnel z may be necess>y to c>ry out ?is *apt]4 #gijd4 ,bo>d mission & functions 7a7 ,mission ,! mission ( ! ,bo>d %all be to issue an indep5d5t det]m9ation z to :e!r an ag5cy may aw>d ,f$]al fund+ = propos$ life sci5ces rese>*1 :i* %all be b9d+ ^u ! ag5cy4 7b7 ,p[]s ,! ,bo>d %all h ! au?ority to act 9 a mann] to c>ry out ! mission describ$ 9 subsection 7a71 includ+ au?ority to-- 7#a7 prescribe regulations to c>ry out ! responsibilities ( ! ,bo>d2 7#b7 e/abli% a process = ! review ( ,f$]al fund+ = life sci5ces rese>* prior to ! aw>d ( ! ,f$]al fund+1 :i* %all be b9d+ ^u an ag5cy1 includ+ in=mation designat$ z classifi$ or o!rwise protect$ f disclosure2 7#c7 direct an ag5cy to make available to ! ,bo>d additional in=mation & records1 includ+ in=mation designat$ z classifi$ or o!rwise protect$ f disclosure1 t ! ,bo>d det]m9es are requir$ to fulfill ! functions & responsibilities ,bo>d "u ?is *apt]2 7#d7 review any classifi$ rese>* conduct$ or fund$ by any ag5cy to det]m9e :e!r ! rese>* w\ld be consid]$ high-risk life sci5ces rese>*2 7#e7 ?r\gh ! promulgation ( regulations1 e/abli% processes1 policies1 & proc$ures ( ! ,bo>d = r5d]+ decisions "u ?is *apt]2 & 7#f7 by majority vote1 add an ag5t or tox9 to ! def9ition ( ag5t or tox9 "u section #gija4 7c7 ,initial requirem5ts ,! ,bo>d %all-- 7#a7 n lat] ?an #ij days aft] ! date ( appo9tm5t ( ! initial memb]s ( ! ,bo>d "u section #gijb1 publi% proc$ures 9 ! ,f$]al ,regi/] e/abli%+ ! process = ! review by ! ,bo>d "u section #gijf 2 7#b7 prior to ! e/abli%m5t ( ! proc$ures "u p>agraph 7#a71 consult ) ! appropriate congressional committees & heads ( ag5cies = purposes ( develop+ su* proc$ures2 & 7#c7 n lat] ?an #ahj days aft] ! date ( ! enactm5t ( ?is *apt]1 beg9 c>ry+ out ! duties describ$ 9 section #gijf4 7d7 ,responsiv5ess to ,congress ,not)/&+ any o!r provision ( law1 n lat] ?an #cj days aft] ! date on :i* ! ,bo>d receives a reque/ = in=mation f a ,memb] ( ,congress1 ! ,bo>d %all respond to ! reque/4 7e7 ,congressional brief+s ,n less frequ5tly ?an qu>t]ly1 ! ,bo>d %all brief ! appropriate congressional committees on ! "w ( ! ,bo>d4 #gije4 ,ag5cy proc$ures2 ref]ral to ,bo>d 7a7 ,9 g5]al ,beg9n+ #ahj days aft] ! date ( enactm5t ( ?is *apt]1 ! head ( an ag5cy-- 7#a7 may n aw>d ,f$]al fund+ = high-risk life sci5ces rese>* )\t approval by ! ,bo>d "u section #gijf7;a77#a77;,b72 & 7#b7 may n aw>d ,f$]al fund+ = life sci5ces rese>* disapprov$ ( by ! ,bo>d "u section #gijf7;a77#b77;,a77i77,,ii74 7b7 ,high-,risk atte/ation2 select ag5t or tox9 disclosure2 c]tification 7#a7 ,9 g5]al ,an entity seek+ ,f$]al fund+ f an ag5cy = life sci5ces rese>* %all1 "u ! p5alty ( p]jury-- 7,a7 atte/ :e!r-- 7i7 ! life sci5ces rese>* w con/itute high-risk life sci5ces rese>*2 & 7ii7 ! entity is p]=m+ active rese>* ) a select ag5t or tox92 & 7,b7 if ! entity is makes a positive atte/ation "u subp>agraph 7,a71 disclose ! s\rce ( fund+ = all active rese>*4 7#b7 ,active rese>* ) select ag5ts or tox9s 7,a7 ,9 g5]al ,! head ( an ag5cy t receives a disclosure f an entity "u p>agraph 7#a77;,b7 %all submit to ! ,bo>d ! disclosure4 7,b7 ,bo>d inquiries ,! ,bo>d may contact an entity t submits a disclosure "u p>agraph 7#a77;,b7 to reque/ additional in=mation relat+ to ! disclosure4 7#c7 ,ag5cy c]tification 7,a7 ,positive atte/ations ,! head ( an ag5cy mak+ an aw>d ( ,f$]al fund+ to an entity t makes a positive atte/ation "u p>agraph 7#a77;,a77i7 %all-- 7i7 submit to ! ,bo>d ! high-risk life sci5ces proposal2 & 7ii7 us+ ! process e/abli%$ by ! head ( ! ag5cy "u p>agraph 7#d71 c]tify ! validity ( ! atte/ation4 7,b7 ,negative atte/ations ,! head ( an ag5cy mak+ an aw>d ( ,f$]al fund+ to an entity t makes a negative atte/ation "u p>agraph 7#a77;,a77i7 %all-- 7i7 review ! atte/ation2 & 7ii7 us+ ! process e/abli%$ by ! head ( ! ag5cy "u p>agraph 7#d71 c]tify ! validity ( ! atte/ation4 7#d7 ,process = review ,! head ( ea* ag5cy t aw>ds ,f$]al fund+ = life sci5ces rese>*1 9 consultation ) ! ,bo>d1 %all e/abli% & implem5t a process = id5tify+ proposals f entities seek+ ,f$]al fund+ = life sci5ces rese>* f ! ag5cy t w con/itute high-risk life sci5ces rese>*4 7#e7 ,ma9t5ance ( records ,! head ( ea* ag5cy %all-- 7,a7 ma9ta9 records ( ! c]tification process describ$ 9 p>agraph 7#c77;,b7 = ea* application = ,f$]al fund+2 & 7,b7 make ! records ma9ta9$ "u subp>agraph 7,a7 available = audit & review ^u reque/ by ! ,bo>d4 7c7 ,notification 7#a7 ,9 g5]al ,n lat] ?an #cj days be=e ! date on :i* ! head ( an ag5cy plans to aw>d ,f$]al fund+ to an entity = life sci5ces rese>*1 ! head ( ! ag5cy %all submit to ! ,bo>d a notification ( ! propos$ ,f$]al fund+ = review "u section #gijf7;a74 7#b7 ,cont5ts ,! notification ( ,f$]al fund+ = life sci5ces rese>* requir$ "u p>agraph 7#a7 %all include ! atte/ation & c]tification requir$ "u subsection 7b74 7d7 ,ag5cy proc$ures ,n lat] ?an #ahj days aft] ! date on :i* ! ,bo>d publi%es ! process ( ! ,bo>d 9 ! ,f$]al ,regi/] pursuant to section #gijd7;c71 ! head ( ea* ag5cy %all publi% on ! website ( ! ag5cy prepaym5t & preaw>d proc$ures ( ! ag5cy ) respect to ,f$]al fund+ = life sci5ces rese>* to-- 7#a7 gu>antee t-- 7,a7 all life sci5ce rese>* proposals are ref]r$ to ! ,bo>d be=e ! aw>d ( ,f$]al fund+ by ! ag5cy2 & 7,b7 no ,f$]al fund+ = high-risk life sci5ces rese>* is aw>d$ by ! ag5cy )\t approval by ! ,bo>d2 & 7#b7 o!rwise ensure compliance ) ?is *apt]4 7e7 ,provision ( additional in=mation ,^u reque/ by ! ,bo>d1 ! head ( an ag5cy %all provide any in=mation relat+ to ,f$]al fund+ aw>ds = life sci5ces rese>* det]m9$ necess>y by ! ,bo>d to provide ov]sight ( ! ag5cy4 7f7 ,*ange 9 circum/ances dur+ rese>* ,if1 dur+ ! c\rse ( life sci5ces rese>* 9 progress p]=m$ by an entity support$ by ,f$]al fund+ f an ag5cy1 circum/ances arise su* t ! life sci5ces rese>* 9 progress may con/itute high-risk life sci5ces rese>* 9 contrav5tion to ! atte/ation ( ! entity "u subsection 7b77#a77;,a77i7-- 7#a7 ! entity %all-- 7,a7 pause ! life sci5ces rese>* 9 progress2 & 7,b7 notify ! head ( ! ag5cy ( ! possibility t ! life sci5ces rese>* 9 progress may con/itute high-risk life sci5ces rese>*2 & 7#b7 ! head ( ! ag5cy %all-- 7,a7 us+ ! process ( ! ag5cy e/abli%$ "u subsection 7b77#d71 det]m9e :e!r ! life sci5ces rese>* 9 progress con/itutes high-risk life sci5ces rese>*2 7,b7 if ! head ( ! ag5cy makes a negative det]m9ation "u subp>agraph 7,a71 in=m ! entity t ! entity may resume ! life sci5ces rese>* 9 progress2 & 7,c7 if ! head ( ! ag5cy makes a positive det]m9ation "u subp>agraph 7,a71 imm$iately submit to ! ,bo>d a notification ( ! ,f$]al fund+ ( high-risk life sci5ces rese>* 9 progress = review "u section #gijf7;a77#a74 7g7 ,en=cem5t 7#a7 ,applicant requirem5ts ,if an entity seek+ or receiv+ ,f$]al fund+ f an ag5cy fails to make a true atte/ation "u subsection 7b77#a7 or promptly notify ! ag5cy ( *anges describ$ 9 subsection 7f71 ! inspector g5]al ( ! ag5cy may p]man5tly disqualify ! entity f receiv+ any ,f$]al fund+4 7#b7 ,ref]ral to attorney g5]al ,! ,bo>d %all ref] any (ficial ( an ag5cy responsible = ov]see+ & review+ rese>* proposals relat+ to ,f$]al fund+ t fails to comply ) subsection 7b77#c7 to ! inspector g5]al ( ! ag5cy4 7#c7 ,employee discipl9e 7,a7 ,9 g5]al ,not)/&+ any provision ( title #e1 & subject to subp>agraph 7,b71 ! head ( an ag5cy employ+ an employee :o violates any provision ( subsection 7b77#c7 7or1 9 ! case ( ! head ( an ag5cy :o violates any provision ( subsection 7b77#c71 ! ,presid5t7 %all impose on t employee-- 7i7 discipl9>y action consi/+ ( removal1 r$uction 9 grade1 susp5sion1 or deb>m5t f employm5t ) ! ,unit$ ,/ates2 7ii7 a civil p5alty 9 an am\nt t is n less ?an #aj1jjj2 7iii7 ineligibility = any annuity "u *apt] #hc or #hd ( title #e2 & 7iv7 p]man5t revocation ( any applicable security cle>ance held by ! employee4 7,b7 ,specific contractor discipl9e ,9 ! case ( an individual describ$ 9 section #gija7e7 work+ "u a contract ) an ag5cy :o violates any provision ( subsection 7b77#b71 9 addition to any discipl9e t may be applicable "u subp>agraph 7,a7 ( ?is p>agraph1 t individual %all be b>r$ f work+ "u any contract ) ! ,f$]al ,gov]nm5t4 7,c7 ,employee discipl9e reports 7i7 ,9 g5]al ,n lat] ?an #cfj days aft] ! date ( enactm5t ( ?is ,act1 & n less frequ5tly ?an once e #ij days !reaft]1 ! head ( ea* ag5cy %all submit to ! ,bo>d & ! appropriate congressional committees a report t discloses1 = ! p]iod cov]$ by ! report1 ea* violation by an employee ( ! ag5cy ( subsection 7b77#c74 7ii7 ,cont5ts ,ea* report submitt$ "u clause 7i7 %all include1 ) respect to a violation describ$ 9 t clause-- 7,i7 ! "n & pr(essional title ( ea* employee engag$ 9 ! violation2 7,,ii7 a detail$ explanation ( ! nature ( ! violation2 & 7,,iii7 ! date ( ! violation4 7iii7 ,publication ,n lat] ?an #e days aft] ! date on :i* ! ,bo>d receives a report "u clause 7i71 ! ,bo>d %all-- 7,i7 collect ! report & assign ! report a unique track+ numb]2 & 7,,ii7 publi% on a publicly accessible & se>*able website ! cont5ts ( ! report & ! track+ numb] = ! report4 7h7 ,subaw>d & subcontractor disclosure 7#a7 ,9 g5]al ,dur+ ! c\rse ( life sci5ces rese>* 9 progress p]=m$ by an entity support$ by ,f$]al fund+ f an ag5cy1 ! entity %all cont9u\sly disclose to ! head ( ! ag5cy any subcontracts or subaw>ds made ) ! ,f$]al fund+4 7#b7 ,ag5cy submission ,n lat] ?an #cj days aft] ! date on :i* ! head ( an ag5cy receives a disclosure "u p>agraph 7#a71 ! head ( ! ag5cy %all submit to ! ,bo>d ! disclosure4 7#c7 ,bo>d inquiries 7,a7 ,9 g5]al ,! ,bo>d may contact an entity t submits a disclosure "u p>agraph 7#a7 to reque/ additional in=mation relat+ to ! disclosure4 7,b7 ,access to reports ,dur+ ! c\rse ( life sci5ces rese>* 9 progress p]=m$ by an entity support$ by ,f$]al fund+ f an ag5cy1 ^u reque/1 ! ,bo>d %all h access to e annual report-- 7i7 ( ! ag5cy2 7ii7 ( ! entity p]=m+ ! life sci5ces rese>*2 & 7iii7 ( any subaw>dee ( an entity describ$ 9 clause 7ii74 #gijf4 ,bo>d review 7a7 ,9 g5]al 7#a7 ,high-risk life sci5ces rese>* ,n lat] ?an #abj days aft] ! date on :i* ! ,bo>d receives a notification f an ag5cy "u section #gije7;c7 relat+ to propos$ ,f$]al fund+ = life sci5ces rese>* t con/itutes high-risk life sci5ces rese>* or a notification f an ag5cy "u section #gije7;f77#b77;,c7 relat+ to ,f$]al fund+ ( rese>* 9 progress t con/itutes high-risk life sci5ces rese>*1 ! ,bo>d %all-- 7,a7 review ! propos$ ,f$]al fund+ or rese>* 9 progress2 7,b7 by a majority vote1 det]m9e :e!r ! ag5cy may aw>d ! propos$ ,f$]al fund+ or cont9ue to aw>d ! ,f$]al fund+ = ! rese>* 9 progress2 & 7,c7 by a majority vote1 det]m9e ) respect to ! life sci5ces rese>* fund$ by ! propos$ ,f$]al fund+ or ,f$]al fund+ = rese>* 9 progress-- 7i7 ! m9imum requir$ biosafety conta9m5t level1 eng9e]+ controls1 & op]ational controls2 7ii7 ! m9imum requir$ biosecurity eng9e]+ controls & op]ational controls2 & 7iii7 ! m9imum requir$ p]sonnel assurance controls4 7#b7 ,life sci5ces rese>* 7,a7 ,propos$ fund+ 7i7 ,9 g5]al ,) respect to propos$ ,f$]al fund+ by an ag5cy = life sci5ces rese>* t does n con/itute high-risk life sci5ces rese>*1 ! ,bo>d may-- 7,i7 review ! propos$ ,f$]al fund+2 & 7,,ii7 by a majority vote1 det]m9e :e!r ! ag5cy may aw>d ! propos$ ,f$]al fund+4 7ii7 ,notification ,if ! ,bo>d det]m9es n to p]mit ! aw>d ( ,f$]al fund+ propos$ by an ag5cy pursuant to clause 7i77,,ii71 ! ,bo>d %all notify ! head ( ! ag5cy & id5tify ! factors t contribut$ to ! det]m9ation ( ! ,bo>d4 7,b7 ,pa/ fund+ ,) respect to ,f$]al fund+ t has already be5 aw>d$ by an ag5cy = life sci5ces rese>* t does n con/itute high-risk life sci5ces rese>*1 ! ,bo>d may review & audit ! life sci5ces rese>*4 7b7 ,consid]ations 7#a7 ,9 g5]al ,9 mak+ a det]m9ation "u p>agraph 7#a77;,b7 & 7#b77;,a77i77,,ii7 ( subsection 7a71 ! ,bo>d %all consid]1 ) respect to ! life sci5ces rese>* t w be conduct$ ) ! propos$ ,f$]al fund+ or rese>* 9 progress-- 7,a7 :e!r ! rese>* poses a ?reat to public heal?2 7,b7 :e!r ! rese>* poses a ?reat to public safety2 7,c7 :e!r ! rese>* has a high probability ( produc+ b5efits = public heal?2 7,d7 :e!r ! rese>* poses a ?reat to l>ge populations ( animals1 & plants2 7,e7 :e!r ! rese>* poses a ?reat to national security2 7,f7 :e!r ! rese>* is propos$ to be conduct$ 9 a =eign c\ntry2 7,g7 ! reasonably anticipat$ mat]ial risks2 7,h7 ! reasonably anticipat$ in=mation risks2 7,i7 ! reasonably anticipat$ b5efits2 7,j7 :e!r ! reasonably anticipat$ b5efits outweigh ! reasonably anticipat$ risks2 & 7,k7 :e!r ! b5efits c\ld be obta9$ ?r\gh proc$ures pos+ l[] risks4 7#b7 ,weight ( factors ,! pres5ce or abs5ce ( any factor "u p>agraph 7#a7 %all n be decisive ) respect to ! det]m9ation ( ! ,bo>d "u p>agraph 7#a77;,b7 & 7#b77;,a77i77,,ii7 ( subsection 7a74 7c7 ,notice foll[+ review & det]m9ation 7#a7 ,ag5cy notification ,n lat] ?an #e days aft] ! date on :i* ! ,bo>d makes a det]m9ation "u subsection 7a77#a77;,b71 ! ,executive ,director ( ! ,bo>d %all notify ! head ( ! ag5cy ( ! det]m9ation4 7#b7 ,notification to appropriate congressional committees ,if ! ,bo>d det]m9es t ! head ( an ag5cy may n proce$ ) an aw>d ( propos$ ,f$]al fund+ "u ?is section1 ! ,executive ,director ( ! ,bo>d %all notify ! appropriate congressional committees :5 ! ,bo>d notifies ! head ( ! ag5cy4 7d7 ,bo>d delegation ( decisionmak+ to au?oriz$ p]sonnel 7#a7 ,9 g5]al ,! ,bo>d may vote to delegate to designat$ p]sonnel ( ! ,bo>d appo9t$ "u section #gijc7;b7 ! au?ority to det]m9e :e!r to review propos$ ,f$]al fund+ = life sci5ces rese>* "u subsection 7a77#b77;,a77i77,i74 7#b7 ,policies & proc$ures ,! delegation au?oriz$ "u p>agraph 7#a7 %all be subject to policies & proc$ures-- 7,a7 unanim\sly approv$ by ! ,bo>d2 7,b7 e/abli%$ 9 consultation ) ! appropriate congressional committees2 & 7,c7 publi%$ 9 ! ,f$]al ,regi/]4 7#c7 ,high-risk life sci5ces rese>* approval ,! ,bo>d may n delegate ! requirem5t to make a review & det]m9ation "u subsection 7a77#a77;i7 ) respect to ,f$]al fund+ = high-risk life sci5ces rese>*4 7e7 ,sci5tific exp]t panels 7#a7 ,9 g5]al ,! ,bo>d may e/abli% a sci5tific panel ( exp]ts to advise ! ,bo>d 9 ! review by ! ,bo>d ( life sci5ces rese>* pursuant to ?is *apt]4 7#b7 ,policies & proc$ures ,! ,bo>d %all e/abli% & publi% 9 ! ,f$]al ,regi/] proc$ures & policies relat+ to conflicts ( int]e/1 recusal1 exp]tise1 & relat$ matt]s be=e ! e/abli%m5t ( ! panel describ$ 9 p>agraph 7#a74 7#c7 ,prohibition ,an individual s]v+ on ! panel e/abli%$ "u p>agraph 7#a7 may n advise ! ,bo>d on any matt] ) respect to :i* ! individuals has an id5tifi$ or p]ceiv$ conflict ( int]e/4 7#d7 ,report 7,a7 ,9 g5]al ,n lat] ?an #cj days aft] ! date on :i* ! ,bo>d e/abli%es a panel e/abli%$ "u p>agraph 7#a71 ! ,bo>d %all submit to ! appropriate congressional committees a report t includes ! names ( individuals :o s]ve on ! panel4 7,b7 ,panel *anges ,^u a *ange ( p]sonnel on ! panel e/abli%$ "u p>agraph 7#a71 ! ,bo>d %all imm$iately submit to ! appropriate congressional committees an update to ! report requir$ "u subp>agraph 7,a74 7f7 ,report ,n lat] ?an #cfj days aft] ! date on :i* ! ,bo>d e/abli%es ! panel describ$ 9 subsection 7e77#a71 & annually !reaft]1 ! ,bo>d %all submit to ! appropriate congressional committees & make available on a website a report summ>iz+1 ) respect to ea* det]m9ation by ! ,bo>d "u ?is section relat+ to life sci5ces rese>*-- 7#a7 ! f9d+s ( ! ,bo>d2 7#b7 ! det]m9ation ( ! ,bo>d2 7#c7 ! "n & location ( ! entity propos+ ! life sci5ces rese>*2 7#d7 ! "n & location ( any recipi5t ( a subaw>d or subcontractor ( an entity propos+ life sci5ces rese>* & ! nature ( ! p>ticipation ( su* a recipi5t or subcontractor2 & 7#e7 an acc\nt ( significant *all5ges or problems1 includ+ proc$ural or sub/antive *all5ges or problems1 t arise dur+ ! c\rse ( ! "w ( ! ,bo>d1 includ+ ! views ( any memb] ( ! ,bo>d :o wi%es to h ^? views includ$ 9 ! report4 7g7 ,effective date ,?is section %all take effect on ! date t is #ahj days aft] ! date ( enactm5t ( ?is *apt]4 #gijg4 ,fund+ 7a7 ,au?orization ( appropriations ,!re is au?oriz$ to be appropriat$ to ! ,bo>d to c>ry out ?is *apt] #cj1jjj1jjj = ea* ( fiscal ye>s #bjbe ?r\gh #bjcd4 7b7 ,,dhs ,transf] 7#a7 ,9 g5]al ,subject to p>agraph 7#b7 & not)/&+ any o!r law1 9 any fiscal ye> = :i* am\nts are au?oriz$ to be appropriat$ "u subsection 7a71 ( ! am\nts ! ,secret>y ( ,homel& ,security w\ld o!rwise aw>d z grants1 ! ,secret>y ( ,homel& ,security %all transf] #cj1jjj1jjj to ! ,bo>d4 7#b7 ,exception ,a transf] "u p>agraph 7#a7 %all n apply to am\nts aw>d$ z grants f ! ,disa/] ,relief ,fund ( ! ,f$]al ,em]g5cy ,managem5t ,ag5cy4 4 7b7 ,cl]ical am5dm5t ,! table ( sections = subtitle ,v ( title #ca1 ,unit$ ,/ates ,code1 is am5d$ by add+ at ! end ! foll[+3 ,*apt] #gi--,life ,sci5ces ,rese>* ,security ,bo>d #gija4 ,def9itions4 #gijb4 ,e/abli%m5t & memb]%ip4 #gijc4 ,bo>d p]sonnel4 #gijd4 ,bo>d mission & functions4 #gije4 ,ag5cy proc$ures2 ref]ral to ,bo>d4 #gijf4 ,bo>d review4 #gijg4 ,fund+4 4 7c7 ,f9ancial disclosure reports ( ,bo>d memb]s ,section #acajc7;f7 ( title #e1 ,unit$ ,/ates ,code1 is am5d$-- 7#a7 9 p>agraph 7#aa71 by /rik+ & at ! end2 7#b7 9 p>agraph 7#ab71 by /rik+ ! p]iod at ! end & ins]t+ 2 &2 & 7#c7 by add+ at ! end ! foll[+3 7#ac7 a memb] ( ! ,life ,sci5ces ,rese>* ,security ,bo>d e/abli%$ "u section #gijb ( title #ca4 4