,,ib ,union ,cal5d> ,no4 #agj #aag? ,,congress #b;d ,session ,h4 ,r4 #deba ,report ,no4 #aag-bce1 ,"p ,i ,,9 ,,! ,,h\se ,,( ,,repres5tatives ,july #ai1 #bjba,ms4 ,johnson ( ,texas 7= h]self & ,mr4 ,lucas7 introduc$ ! foll[+ bill2 :i* 0 ref]r$ to ! ,committee on ,sci5ce1 ,space1 & ,te*nology1 & 9 addition to ! ,committees on ,agriculture1 & ,en]gy & ,comm]ce1 = a p]iod to be subsequ5tly det]m9$ by ! ,speak]1 9 ea* case = consid]ation ( su* provisions z fall )9 ! jurisdiction ( ! committee conc]n$ ,janu>y #bh1 #bjbb;,additional sponsors3 ,mr4 ,g>am5di1 ,mr4 ,neal1 ,mr4 ,nadl]1 ,ms4 ,wat]s1 ,mrs4 ,c>olyn ,b4 ,maloney ( ,new ,york1 ,mr4 ,scott ( ,virg9ia1 ,mr4 ,grijalva1 ,mr4 ,?ompson ( ,mississippi1 ,mr4 ,meeks1 ,mr4 ,tonko1 ,mr4 ,%]man1 ,mr4 ,kildee1 ,mrs4 ,mc,bath1 ,mr4 ,bi%op ( ,georgia1 ,mrs4 ,dem+s1 ,ms4 ,ross1 ,mr4 ,/anton1 ,mr4 ,fo/]1 ,mrs4 ,beatty1 ,mr4 ,mc,nerney1 ,ms4 ,leg] ,f]n&ez1 ,mr4 ,sablan1 ,mr4 ,mfume1 ,mrs4 ,d+ell1 ,mr4 ,sean ,patrick ,maloney ( ,new ,york1 ,mr4 ,mrvan1 ,ms4 ,wilson ( ,florida1 ,mr4 ,doggett1 ,mr4 ,blum5au]1 ,mr4 ,cuell>1 ,miss ,rice ( ,new ,york1 ,mr4 ,huffman1 ,ms4 ,newman1 ,mr4 ,c\rtney1 ,mr4 ,pascrell1 ,mr4 ,morelle1 ,mr4 ,deut*1 ,mr4 ,mi*ael ,f4 ,doyle ( ,p5nsylvania1 ,mr4 ,lyn*1 ,mr4 ,khanna1 ,mr4 ,g>ca ( ,ill9ois1 ,ms4 ,bonamici1 ,ms4 ,blunt ,ro*e/]1 ,mr4 ,cleav]1 ,mrs4 ,axne1 ,mrs4 ,lawr5ce1 ,ms4 ,craig1 ,mr4 ,ca/51 ,mr4 ,butt]field1 ,mr4 ,p]lmutt]1 ,mr4 ,langev91 ,mr4 ,mc,eachin1 ,mr4 ,evans1 ,mr4 ,ru%1 ,ms4 ,titus1 ,ms4 ,/ansbury1 ,mr4 ,aguil>1 ,mr4 ,gre5 ( ,texas1 ,ms4 ,de,lauro1 ,ms4 ,matsui1 ,ms4 ,/ev5s1 ,mr4 ,hors=d1 ,mr4 ,b]a1 ,ms4 ,ku/]1 ,ms4 ,de,gette1 ,mr4 ,l>son ( ,connecticut1 ,mr4 ,co/a1 ,ms4 ,roybal-,all>d1 ,ms4 ,mc,collum1 ,ms4 ,cl>k ( ,massa*usetts1 ,mr4 ,sires1 ,mr4 ,danny ,k4 ,davis ( ,ill9ois1 ,ms4 ,br[nley1 ,ms4 ,kelly ( ,ill9ois1 ,mr4 ,gallego1 ,ms4 ,e%oo1 ,mr4 ,payne1 ,mr4 ,hoy]1 ,ms4 ,b\rdeaux1 ,mr4 ,c>son1 ,mr4 ,jeffries1 ,mrs4 ,torres ( ,cali=nia1 ,mr4 ,bey]1 ,ms4 ,dean1 ,mr4 ,o',hall]an1 ,mr4 ,kim ( ,new ,j]sey1 ,mr4 ,torres ( ,new ,york1 ,mr4 ,?ompson ( ,cali=nia1 ,ms4 ,adams1 ,mr4 ,l>s5 ( ,wa%+ton1 ,mr4 ,kilm]1 ,ms4 ,escob>1 ,mr4 ,allr$1 ,mr4 ,c>twright1 ,mr4 ,swalwell1 ,ms4 ,%]rill1 ,mr4 ,johnson ( ,georgia1 ,ms4 ,velzquez1 ,mr4 ,lawson ( ,florida1 & ,ms4 ,sewell ,janu>y #bh1 #bjbb,report$ f ! ,committee on ,sci5ce1 ,space1 & ,te*nology ) an amendment,strike out all aft] ! enact+ clause & ins]t ! "p pr9t$ 9 italic ,janu>y #bh1 #bjbb;,committees on ,agriculture & ,en]gy & ,comm]ce dis*>g$2 committ$ to ! ,committee ( ! ,:ole ,h\se on ! ,/ate ( ! ,union & ord]$ to be printed,for text ( introduc$ bill1 see copy ( bill z introduc$ on ,july #ai1 #bjba ,a ,,bill ,to provide = a coord9at$ ,f$]al rese>* initiative to ensure cont9u$ ,unit$ ,/ates lead]%ip 9 eng9e]+ biology4 #a4 ,%ort title ,?is ,act may be cit$ z ! ,bioeconomy ,rese>* & ,developm5t ,act ( #bjba4 #b4 ,f9d+s ,! ,congress makes ! foll[+ f9d+s3 7#a7 ,cellul> & molecul> processes may be us$1 mimick$1 or r$esign$ to develop new products1 processes1 & sy/ems t improve societal well-be+1 /r5g!n national security1 & contribute to ! economy4 7#b7 ,eng9e]+ biology relies on a work=ce ) a div]se & unique set ( skills comb9+ ! biological1 physical1 *emical1 & in=mation sci5ces & eng9e]+4 7#c7 ,long-t]m rese>* & developm5t is necess>y to create break?r\ghs 9 eng9e]+ biology4 ,su* rese>* & developm5t requires gov]nm5t inve/m5t z _m ( ! b5efits are too di/ant or unc]ta9 = indu/ry to support alone4 7#d7 ,rese>* is necess>y to in=m evid5ce-bas$ gov]nance ( eng9e]+ biology & to support ! gr[? ( ! eng9e]+ biology indu/ry4 7#e7 ,! ,f$]al ,gov]nm5t has an obligation to ensure t e?ical1 legal1 environm5tal1 safety1 security1 & societal implications ( its sci5ce & te*nology rese>* & inve/m5t foll[s policies ( responsible innovation & fo/]s public transp>5cy4 7#f7 ,! ,f$]al ,gov]nm5t c play an important role by facilitat+ ! developm5t ( tools & te*nologies to fur!r advance eng9e]+ biology1 includ+ us] facilities1 by facilitat+ public-private p>tn]%ips1 by support+ risk rese>*1 & by facilitat+ ! comm]cial application 9 ! ,unit$ ,/ates ( rese>* fund$ by ! ,f$]al ,gov]nm5t4 7#g7 ,! ,unit$ ,/ates l$ ! developm5t ( ! sci5ce & eng9e]+ te*niques t creat$ ! field ( eng9e]+ biology1 b due to increas+ int]national competition1 ! ,unit$ ,/ates is at risk ( los+ its competitive advantage if x does n /rategically inve/ ! necess>y res\rces4 7#h7 ,a ,national ,eng9e]+ ,biology ,initiative c s]ve to e/abli% new rese>* directions & te*nology goals1 improve int]ag5cy coord9ation & plann+ processes1 drive te*nology transf] to ! private sector1 & help ensure optimal returns on ! ,f$]al inve/m5t4 #c4 ,def9itions ,9 ?is ,act3 7#a7 ,biomanufactur+ ,! t]m biomanufactur+ means ! utilization ( biological sy/ems to develop new & advance exi/+ products1 tools1 & processes at comm]cial scale4 7#b7 ,eng9e]+ biology ,! t]m eng9e]+ biology means ! application ( eng9e]+ design pr9ciples & practices to biological sy/ems1 includ+ molecul> & cellul> sy/ems1 to advance fundam5tal und]/&+ ( complex natural sy/ems & to enable novel or optimize functions & capabilities4 7#c7 ,initiative ,! t]m ,initiative means ! ,national ,eng9e]+ ,biology ,rese>* & ,developm5t ,initiative e/abli%$ "u section #d4 7#d7 ,omics ,! t]m omics ref]s to ! collective te*nologies us$ to explore ! roles1 relation%ips1 & actions ( ! v>i\s types ( molecules t make up ! cells ( an organism4 #d4 ,national ,eng9e]+ ,biology ,rese>* & ,developm5t ,initiative 7a7 ,9 g5]al ,! ,presid5t1 act+ ?r\gh ! ,(fice ( ,sci5ce & ,te*nology ,policy1 %all implem5t a ,national ,eng9e]+ ,biology ,rese>* & ,developm5t ,initiative to advance societal well-be+1 national security1 su/a9ability1 & economic productivity & competitiv5ess ?r\gh-- 7#a7 advanc+ areas ( rese>* at ! int]section ( ! biological1 physical1 *emical1 data1 & computational & in=mation sci5ces & eng9e]+ to accel]ate sci5tific und]/&+ & te*nological innovation 9 eng9e]+ biology2 7#b7 advanc+ areas ( biomanufactur+ rese>* to optimize1 /&>dize1 scale1 & deliv] new products & solutions2 7#c7 support+ social & behavioral sci5ces & economics rese>* t advances ! field ( eng9e]+ biology & contributes to ! developm5t & public und]/&+ ( new products1 processes1 & te*nologies2 7#d7 improv+ ! und]/&+ ( eng9e]+ biology ( ! sci5tific & lay public & support+ great] evid5ce-bas$ public disc\rse ab\t its b5efits & risks2 7#e7 support+ rese>* relat+ to ! risks & b5efits ( eng9e]+ biology1 includ+ "u subsection 7d72 7#f7 support+ ! developm5t ( novel tools & te*nologies to accel]ate sci5tific und]/&+ & te*nological innovation 9 eng9e]+ biology2 7#g7 exp&+ ! numb] ( rese>*]s1 educators1 & /ud5ts & a retool$ work=ce ) eng9e]+ biology tra9+1 includ+ f traditionally und]repres5t$ & und]s]v$ populations2 7#h7 accel]at+ ! translation & comm]cialization ( eng9e]+ biology & biomanufactur+ rese>* & developm5t by ! private sector2 & 7#i7 improv+ ! int]ag5cy plann+ & coord9ation ( ,f$]al ,gov]nm5t activities relat$ to eng9e]+ biology4 7b7 ,initiative activities ,! activities ( ! ,initiative %all include-- 7#a7 su/a9$ support = eng9e]+ biology rese>* & developm5t ?r\gh-- 7,a7 grants to fund ! "w ( individual inve/igators & teams ( inve/igators1 includ+ int]discipl9>y teams2 7,b7 projects fund$ "u jo9t solicitations by a collaboration ( no few] ?an two ag5cies p>ticipat+ 9 ! ,initiative2 & 7,c7 int]discipl9>y rese>* c5t]s t are organiz$ to inve/igate basic rese>* que/ions1 c>ry out te*nology developm5t & demon/ration activities1 & increase und]/&+ ( h[ to scale up eng9e]+ biology processes1 includ+ biomanufactur+2 7#b7 su/a9$ support = databases & relat$ tools1 includ+-- 7,a7 support = ! e/abli%m5t1 curation1 & ma9t5ance ( curat$ g5omics1 epig5omics1 & o!r relevant omics databases1 includ+ plant1 animal1 & microbial databases1 t are available to rese>*]s to c>ry out eng9e]+ biology rese>* 9 a mann] t does n compromise national security or ! privacy or security ( in=mation )9 su* databases2 7,b7 developm5t ( /&>ds = su* databases1 includ+ = curation1 int]op]ability1 & protection ( privacy & security2 7,c7 support = ! developm5t ( computational tools1 includ+ artificial intellig5ce tools1 t c accel]ate rese>* & innovation us+ su* databases2 & 7,d7 an inv5tory & assessm5t ( all ,f$]al gov]nm5t omics databases to id5tify opportunities to improve ! utility ( su* databases1 z appropriate & 9 a mann] t does n compromise national security or ! privacy & security ( in=mation )9 su* databases1 & in=m inve/m5t 9 su* databases z critical infra/ructure = ! eng9e]+ biology rese>* ent]prise2 7#c7 su/a9$ support = ! developm5t1 optimization1 & validation ( novel tools & te*nologies to enable ! dynamic /udy ( molecul> processes 9 situ1 includ+ ?r\gh-- 7,a7 rese>* conduct$ at ,f$]al laboratories2 7,b7 grants to fund ! "w ( inve/igators at in/itutions ( high] education & o!r nonpr(it rese>* in/itutions2 7,c7 inc5tiviz$ developm5t ( retool$ indu/rial sites across ! c\ntry t fo/] a pivot to mod]niz$ eng9e]+ biology initiatives2 & 7,d7 aw>ds "u ! ,small ,bus9ess ,innovation ,rese>* ,program & ! ,small ,bus9ess ,te*nology ,transf] ,program1 z describ$ 9 section #i ( ! ,small ,bus9ess ,act 7#ae ,u4,s4,c4 #fch72 7#d7 support = education & tra9+ ( und]graduate & graduate /ud5ts 9 eng9e]+ biology1 biomanufactur+1 bioprocess eng9e]+1 & computational sci5ce appli$ to eng9e]+ biology & 9 ! relat$ e?ical1 legal1 environm5tal1 safety1 security1 & o!r societal doma9s2 7#e7 support = biomanufactur+ te/b$s1 includ+ by repurpos+ exi/+ facilities su* z ^? 9 p>agraph #c7;,c71 t w\ld enable scale up ( laboratory eng9e]+ biology rese>*2 7#f7 activities to develop robu/ me*anisms = docum5t+ & quantify+ ! outputs & economic b5efits ( eng9e]+ biology2 & 7#g7 activities to accel]ate ! translation & comm]cialization ( new products1 processes1 & te*nologies by-- 7,a7 id5tify+ precompetitive rese>* opportunities2 7,b7 facilitat+ public-private p>tn]%ips 9 eng9e]+ biology rese>* & developm5t1 includ+ to address b>ri]s to scal+ up innovations 9 eng9e]+ biology2 7,c7 connect+ rese>*]s1 graduate /ud5ts1 & po/doctoral fell[s ) entrepr5eur%ip education & tra9+ opportunities2 & 7,d7 support+ pro( ( concept activities & ! =mation ( />tup companies includ+ ?r\gh programs su* z ! ,small ,bus9ess ,innovation ,rese>* ,program & ! ,small ,bus9ess ,te*nology ,transf] ,program4 7c7 ,exp&+ p>ticipation ,! ,initiative %all include1 to ! maximum ext5t practicable1 outrea* to prim>ily und]graduate & m9ority-s]v+ in/itutions ab\t ,initiative opportunities1 & %all enc\rage ! developm5t ( rese>* collaborations betwe5 rese>*-int5sive univ]sities & prim>ily und]graduate & m9ority-s]v+ in/itutions4 7d7 ,e?ical1 legal1 environm5tal1 safety1 security1 & societal issues ,initiative activities %all take into acc\nt e?ical1 legal1 environm5tal1 safety1 security1 & o!r appropriate societal issues by-- 7#a7 support+ rese>*1 includ+ 9 ! social sci5ces1 & o!r activities address+ e?ical1 legal1 environm5tal1 & o!r appropriate societal issues relat$ to eng9e]+ biology1 includ+ integrat+ rese>* on su* topics ) ! rese>* & developm5t 9 eng9e]+ biology1 & enc\rag+ ! dissem9ation ( ! results ( su* rese>*1 includ+ ?r\gh int]discipl9>y eng9e]+ biology rese>* c5t]s describ$ 9 subsection 7b77#a72 7#b7 support+ rese>* & o!r activities relat$ to ! safety & security implications ( eng9e]+ biology1 includ+ outrea* to increase aw>5ess among ,f$]al rese>*]s & ,f$]ally-fund$ rese>*]s at in/itutions ( high] education ab\t pot5tial safety & security implications ( eng9e]+ biology rese>*1 z appropriate2 7#c7 ensur+ t input f ,f$]al & non-,f$]al exp]ts on ! e?ical1 legal1 environm5tal1 safety1 security1 & o!r appropriate societal issues relat$ to eng9e]+ biology is integrat$ into ! ,initiative2 7#d7 ensur+1 ?r\gh ! ag5cies & dep>tm5ts t p>ticipate 9 ! ,initiative1 t public input & outrea* are integrat$ into ! ,initiative by ! conv5+ ( regul> & ongo+ public discussions ?r\gh me*anisms su* z work%ops1 cons5sus conf]5ces1 & educational ev5ts1 z appropriate2 & 7#e7 comply+ ) all applicable provisions ( ,f$]al law4 #e4 ,initiative coord9ation 7a7 ,int]ag5cy committee ,! ,presid5t1 act+ ?r\gh ! ,(fice ( ,sci5ce & ,te*nology ,policy1 %all designate an int]ag5cy committee to coord9ate activities ( ! ,initiative z appropriate1 :i* %all be co-*air$ by ! ,(fice ( ,sci5ce & ,te*nology ,policy1 & include repres5tatives f ! ,national ,sci5ce ,f\ndation1 ! ,dep>tm5t ( ,en]gy1 ! ,national ,a]onautics & ,space ,adm9i/ration1 ! ,national ,in/itute ( ,/&>ds & ,te*nology1 ! ,environm5tal ,protection ,ag5cy1 ! ,national ,oceanic & ,atmosph]ic ,adm9i/ration1 ! ,dep>tm5t ( ,agriculture1 ! ,dep>tm5t ( ,heal? & ,human ,s]vices1 ! ,bureau ( ,economic ,analysis1 & any o!r ag5cy t ! ,presid5t consid]s appropriate 79 ?is section ref]r$ to z ! ,int]ag5cy ,committee74 ,! ,director ( ! ,(fice ( ,sci5ce & ,te*nology ,policy %all select an additional co-*airp]son f among ! memb]s ( ! ,int]ag5cy ,committee4 ,! ,int]ag5cy ,committee %all ov]see ! plann+1 managem5t1 & coord9ation ( ! ,initiative4 ,! ,int]ag5cy ,committee %all-- 7#a7 provide = int]ag5cy coord9ation ( ,f$]al eng9e]+ biology rese>*1 developm5t1 & o!r activities und]tak5 pursuant to ! ,initiative2 7#b7 e/abli% & p]iodically update goals & priorities = ! ,initiative2 7#c7 develop1 n lat] ?an #ab mon?s aft] ! date ( ! enactm5t ( ?is ,act1 & update e #c ye>s !reaft]1 a /rategic plan submitt$ to ! ,committee on ,sci5ce1 ,space1 & ,te*nology & ! ,committee on ,en]gy & ,comm]ce ( ! ,h\se ( ,repres5tatives & ! ,committee on ,comm]ce1 ,sci5ce1 & ,transportation & ! ,committee on ,heal?1 ,education1 ,labor1 & ,p5sions ( ! ,s5ate t-- 7,a7 guides ! activities ( ! ,initiative = purposes ( meet+ ! goals & priorities e/abli%$ "u 7& updat$ pursuant to7 p>agraph 7#b72 & 7,b7 describes-- 7i7 ! ,initiative's support = long-t]m fund+ = int]discipl9>y eng9e]+ biology rese>* & developm5t2 7ii7 ! ,initiative's support = education & public outrea* activities2 7iii7 ! ,initiative's support = rese>* & o!r activities on e?ical1 legal1 environm5tal1 safety1 security1 & o!r appropriate societal issues relat$ to eng9e]+ biology includ+-- 7,i7 an appli$ biorisk managem5t rese>* plan2 7,,ii7 recomm5dations = integrat+ security into biological data access & int]national reciprocity agreem5ts2 7,,iii7 recomm5dations = manufactur+ re/ructur+ to support eng9e]+ biology rese>*1 developm5t1 & scal+-up initiatives2 & 7,,iv7 an evaluation ( exi/+ biosecurity gov]nance policies1 guidance1 & directives = ! purposes ( creat+ an adaptable1 evid5ce-bas$ framework to respond to em]g+ biosecurity *all5ges creat$ by advances 9 eng9e]+ biology2 7iv7 h[ ! ,initiative w contribute to mov+ results out ( ! laboratory & into application = ! b5efit ( society & ,unit$ ,/ates competitiv5ess2 & 7v7 h[ ! ,initiative w measure & track ! contributions ( eng9e]+ biology to ,unit$ ,/ates economic gr[? & o!r societal indicators2 7#d7 develop a national g5omic sequ5c+ /rategy to ensure eng9e]+ biology rese>* fully lev]ages plant1 animal1 & microbe biodiv]sity1 z appropriate & 9 a mann] t does n compromise national security or ! privacy or security ( human g5etic in=mation1 to enhance long-t]m innovation & competitiv5ess 9 eng9e]+ biology 9 ! ,unit$ ,/ates2 7#e7 develop a plan to utilize ,f$]al programs1 su* z ! ,small ,bus9ess ,innovation ,rese>* ,program & ! ,small ,bus9ess ,te*nology ,transf] ,program z describ$ 9 section #i ( ! ,small ,bus9ess ,act 7#ae ,u4,s4,c4 #fch71 9 support ( ! activities describ$ 9 section #d7;b77#c72 & 7#f7 9 c>ry+ out ?is section1 take into consid]ation ! recomm5dations ( ! advisory committee e/abli%$ "u section #f1 ! results ( ! work%op conv5$ "u section #g1 exi/+ reports on relat$ topics1 & ! views ( academic1 ,/ate1 indu/ry1 & o!r appropriate gr\ps4 7b7 ,tri5nial report ,beg9n+ ) fiscal ye> #bjbb & end+ 9 fiscal ye> #bjbh1 n lat] ?an #ij days aft] submission ( ! ,presid5t's annual budget reque/ & e ?ird fiscal ye> !reaft]1 ! ,int]ag5cy ,committee %all prep>e & submit to ! ,committee on ,sci5ce1 ,space1 & ,te*nology ( ! ,h\se ( ,repres5tatives & ! ,committee on ,comm]ce1 ,sci5ce1 & ,transportation ( ! ,s5ate a report t includes-- 7#a7 a summ>iz$ ag5cy budget 9 support ( ! ,initiative = ! fiscal ye> to :i* su* budget reque/ applies1 = ! foll[+ #b fiscal ye>s1 = ! !n curr5t fiscal ye>1 includ+ a break\t ( sp5d+ = ea* ag5cy p>ticipat+ 9 ! ,program1 & = ! developm5t & acquisition ( any rese>* facilities & in/rum5tation2 & 7#b7 an assessm5t ( h[ ,f$]al ag5cies are implem5t+ ! plan describ$ 9 subsection 7a77#c71 includ+-- 7,a7 a description ( ! am\nt & numb] ( aw>ds made "u ! ,small ,bus9ess ,innovation ,rese>* ,program & ! ,small ,bus9ess ,te*nology ,transf] ,program 7z describ$ 9 section #i ( ! ,small ,bus9ess ,act 7#ae ,u4,s4,c4 #fch77 9 support ( ! ,initiative2 7,b7 a description ( ! am\nt & numb] ( projects fund$ "u jo9t solicitations by a collaboration ( no few] ?an #b ag5cies p>ticipat+ 9 ! ,initiative2 & 7,c7 a description ( ! effect ( ! newly fund$ projects by ! ,initiative4 7c7 ,initiative (fice 7#a7 ,9 g5]al ,! ,presid5t %all e/abli% an ,initiative ,coord9ation ,(fice1 ) a ,director & full-"t /aff1 :i* %all-- 7,a7 provide te*nical & adm9i/rative support to ! int]ag5cy committee & ! advisory committee e/abli%$ "u section #f2 7,b7 s]ve z ! po9t ( contact on ,f$]al eng9e]+ biology activities = gov]nm5t organizations1 academia1 indu/ry1 pr(essional societies1 ,/ate gov]nm5ts1 int]e/$ citiz5 gr\ps1 & o!rs to ex*ange te*nical & programmatic in=mation2 7,c7 ov]see int]ag5cy coord9ation ( ! ,initiative1 includ+ by enc\rag+ & support+ jo9t ag5cy solicitation & selection ( applications = fund+ ( activities "u ! ,initiative1 z appropriate2 7,d7 conduct public outrea*1 includ+ dissem9ation ( f9d+s & recomm5dations ( ! advisory committee e/abli%$ "u section #f1 z appropriate2 7,e7 s]ve z ! coord9ator ( e?ical1 legal1 environm5tal1 safety1 security1 & o!r appropriate societal input2 & 7,f7 promote access to1 & e>ly application (1 ! te*nologies1 innovations1 & exp]tise d]iv$ f ,initiative activities to ag5cy missions & sy/ems across ! ,f$]al ,gov]nm5t1 & to ,unit$ ,/ates indu/ry1 includ+ />tup companies4 7#b7 ,fund+ ,! ,director ( ! ,(fice ( ,sci5ce & ,te*nology ,policy1 9 coord9ation ) ea* p>ticipat+ ,f$]al dep>tm5t & ag5cy1 z appropriate1 %all develop & annually update an e/imate ( ! funds necess>y to c>ry out ! activities ( ! ,initiative ,coord9ation ,(fice & submit su* e/imate ) an agre$ summ>y ( contributions f ea* ag5cy to ,congress z "p ( ! ,presid5t's annual budget reque/ to ,congress4 7#c7 ,t]m9ation ,! ,initiative ,coord9ation ,(fice e/abli%$ "u ?is subsection %all t]m9ate on ! date t is #aj ye>s aft] ! date ( ! enactm5t ( ?is ,act4 7d7 ,rule ( con/ruction ,no?+ 9 ?is section %all be con/ru$ to alt] ! policies1 processes1 or practices ( individual ,f$]al ag5cies 9 effect on ! day be=e ! date ( ! enactm5t ( ?is ,act relat+ to ! conduct ( biom$ical rese>* & advanc$ developm5t1 includ+ ! solicitation & review ( extramural rese>* proposals4 #f4 ,advisory committee 7a7 ,9 g5]al ,! ag5cy co-*air ( ! int]ag5cy committee e/abli%$ 9 section #e %all1 9 consultation ) ! ,(fice ( ,sci5ce & ,te*nology ,policy1 designate or e/abli% an advisory committee on eng9e]+ biology rese>* & developm5t 79 ?is section ref]r$ to z ! advisory committee7 to be compos$ ( n few] ?an #ab memb]s1 includ+ repres5tatives ( rese>* & academic in/itutions1 indu/ry1 & nongov]nm5tal entities1 :o are qualifi$ to provide advice on ! ,initiative4 7b7 ,assessm5t ,! advisory committee %all assess-- 7#a7 ! curr5t /ate ( ,unit$ ,/ates competitiv5ess 9 eng9e]+ biology1 includ+ ! scope & scale ( ,unit$ ,/ates inve/m5ts 9 eng9e]+ biology rese>* & developm5t 9 ! int]national context2 7#b7 curr5t m>ket b>ri]s to comm]cialization ( eng9e]+ biology products1 processes1 & tools 9 ! ,unit$ ,/ates2 7#c7 progress made 9 implem5t+ ! ,initiative2 7#d7 ! ne$ to revise ! ,initiative2 7#e7 ! balance ( activities & fund+ across ! ,initiative2 7#f7 :e!r ! /rategic plan develop$ or updat$ by ! int]ag5cy committee e/abli%$ "u section #e is help+ to ma9ta9 ,unit$ ,/ates lead]%ip 9 eng9e]+ biology2 7#g7 ! managem5t1 coord9ation1 implem5tation1 & activities ( ! ,initiative2 & 7#h7 :e!r e?ical1 legal1 environm5tal1 safety1 security1 & o!r appropriate societal issues are adequately address$ by ! ,initiative4 7c7 ,reports ,beg9n+ n lat] ?an #b ye>s aft] ! date ( enactm5t ( ?is ,act1 & n less frequ5tly ?an once e #c ye>s !reaft]1 ! advisory committee %all submit to ! ,presid5t1 ! ,committee on ,sci5ce1 ,space1 & ,te*nology ( ! ,h\se ( ,repres5tatives1 & ! ,committee on ,comm]ce1 ,sci5ce1 & ,transportation ( ! ,s5ate1 a report on-- 7#a7 ! f9d+s ( ! advisory committee's assessm5t "u subsection 7b72 & 7#b7 ! advisory committee's recomm5dations = ways to improve ! ,initiative4 7d7 ,application ( ,f$]al ,advisory ,committee ,act ,section #ad ( ! ,f$]al ,advisory ,committee ,act 7#e ,u4,s4,c4 ,app47 %all n apply to ! ,advisory ,committee4 7e7 ,t]m9ation ,! advisory committee e/abli%$ "u subsection 7a7 %all t]m9ate on ! date t is #aj ye>s aft] ! date ( ! enactm5t ( ?is ,act4 #g4 ,ext]nal review ( e?ical1 legal1 environm5tal1 safety1 security1 & societal issues 7a7 ,9 g5]al ,n lat] ?an #f mon?s aft] ! date ( enactm5t ( ?is ,act1 ! ,director ( ! ,national ,sci5ce ,f\ndation %all seek to ent] into an agreem5t ) ! ,national ,academies ( ,sci5ces1 ,eng9e]+1 & ,m$ic9e to conduct a review1 & make recomm5dations ) respect to1 ! e?ical1 legal1 environm5tal1 safety1 security1 & o!r appropriate societal issues relat$ to eng9e]+ biology rese>* & developm5t4 ,! review %all include-- 7#a7 an assessm5t ( ! curr5t rese>* on su* issues2 7#b7 a description ( ! rese>* gaps relat+ to su* issues2 7#c7 recomm5dations on h[ ! ,initiative c address ! rese>* ne$s id5tifi$ pursuant to p>agraph 7#b72 & 7#d7 recomm5dations on h[ rese>*]s engag$ 9 eng9e]+ biology c be/ incorporate consid]ations ( e?ical1 legal1 environm5tal1 safety1 security1 & o!r societal issues into ! developm5t ( rese>* proposals & ! conduct ( rese>*4 7b7 ,report to ,congress ,! agreem5t ent]$ into "u subsection 7a7 %all require ! ,national ,academies ( ,sci5ces1 ,eng9e]+1 & ,m$ic9e to1 n lat] ?an #b ye>s aft] ! date ( ! enactm5t ( ?is ,act-- 7#a7 submit to ! ,committee on ,sci5ce1 ,space1 & ,te*nology ( ! ,h\se ( ,repres5tatives & ! ,committee on ,comm]ce1 ,sci5ce1 & ,transportation ( ! ,s5ate a report conta9+ ! f9d+s & recomm5dations ( ! review conduct$ "u subsection 7a72 & 7#b7 make a copy ( su* report available on a publicly accessible website4 #h4 ,ag5cy activities 7a7 ,national ,sci5ce ,f\ndation ,z "p ( ! ,initiative1 ! ,national ,sci5ce ,f\ndation %all-- 7#a7 support rese>* 9 eng9e]+ biology & biomanufactur+ ?r\gh individual grants1 collaborative grants1 & ?r\gh int]discipl9>y rese>* c5t]s2 7#b7 support rese>* on ! environm5tal1 legal1 e?ical1 & social implications ( eng9e]+ biology2 7#c7 provide support = rese>* in/rum5tation1 equipm5t1 & cyb]9fra/ructure = eng9e]+ biology discipl9es1 includ+ support = rese>*1 developm5t1 optimization & validation ( novel te*nologies to enable ! dynamic /udy ( molecul> processes 9 situ2 7#d7 support curriculum developm5t & rese>* exp]i5ces = second>y1 und]graduate1 & graduate /ud5ts 9 eng9e]+ biology & biomanufactur+1 includ+ ?r\gh support = graduate fell[%ips & tra9ee%ips 9 eng9e]+ biology2 & 7#e7 aw>d grants1 on a competitive basis1 to enable in/itutions to support graduate /ud5ts & po/doctoral fell[s :o p]=m "s ( _! eng9e]+ biology rese>* 9 an indu/ry sett+4 7b7 ,dep>tm5t ( ,comm]ce 7#a7 ,national ,in/itute ( ,/&>ds & ,te*nology ,z "p ( ! ,initiative1 ! ,director ( ! ,national ,in/itute ( ,/&>ds & ,te*nology %all-- 7,a7 e/abli% a biosci5ce rese>* program to advance ! developm5t ( /&>d ref]5ce mat]ials & measurem5ts & to create new data tools1 te*niques1 & processes necess>y to advance eng9e]+ biology & biomanufactur+2 7,b7 provide access to us] facilities ) advanc$ or unique equipm5t1 s]vices1 mat]ials1 & o!r res\rces to indu/ry1 in/itutions ( high] education1 nonpr(it organizations1 & gov]nm5t ag5cies to p]=m rese>* & te/+2 & 7,c7 provide te*nical exp]tise to in=m ! pot5tial developm5t ( guidel9es or safegu>ds = new products1 processes1 & sy/ems ( eng9e]+ biology4 7#b7 ,national ,oceanic & ,atmosph]ic ,adm9i/ration ,z "p ( ! initiative1 ! ,adm9i/rator ( ! ,national ,oceanic & ,atmosph]ic ,adm9i/ration %all-- 7,a7 conduct & support rese>* 9 omics & associat$ bio9=matic sci5ces & develop tools & products to improve ecosy/em /ew>d%ip1 monitor+1 managem5t1 assessm5ts & =eca/s1 consi/5t ) ! mission ( ! ag5cy2 & 7,b7 collaborate ) o!r ag5cies to und]/& pot5tial environm5tal ?reats & safegu>ds relat$ to eng9e]+ biology4 7c7 ,dep>tm5t ( ,en]gy ,z "p ( ! ,initiative1 ! ,secret>y ( ,en]gy %all-- 7#a7 conduct & support rese>*1 developm5t1 demon/ration1 & comm]cial application activities 9 eng9e]+ biology1 includ+ 9 ! areas ( syn!tic biology1 advanc$ bi(uel & bioproduct developm5t1 biobas$ mat]ials1 & environm5tal rem$iation2 7#b7 support ! developm5t1 optimization & validation ( novel1 scalable tools & te*nologies to enable ! dynamic /udy ( molecul> processes 9 situ2 7#c7 provide access to us] facilities ) advanc$ or unique equipm5t1 s]vices1 mat]ials1 & o!r res\rces1 includ+ secure access to high-p]=mance comput+1 z appropriate1 to indu/ry1 in/itutions ( high] education1 nonpr(it organizations1 & gov]nm5t ag5cies to p]=m rese>* & te/+2 & 7#d7 /r5g!n collaboration betwe5 ! ,(fice ( ,sci5ce & ! ,en]gy ,effici5cy & ,r5ewable ,en]gy ,(fice to help transf] fundam5tal rese>* results to indu/ry & accel]ate comm]cial applications4 7d7 ,national ,a]onautics & ,space ,adm9i/ration ,z "p ( ! ,initiative1 ! ,national ,a]onautics & ,space ,adm9i/ration %all-- 7#a7 conduct & support rese>* 9 eng9e]+ biology1 includ+ 9 syn!tic biology1 & relat$ to ,e>? & space sci5ces1 a]onautics1 space te*nology1 & space exploration & exp]im5tation1 consi/5t ) ! priorities e/abli%$ 9 ! ,national ,academies' decadal surveys2 & 7#b7 aw>d grants1 on a competitive basis1 t enable in/itutions to support graduate /ud5ts & po/doctoral fell[s :o p]=m "s ( _! eng9e]+ biology rese>* 9 an indu/ry sett+4 7e7 ,dep>tm5t ( ,agriculture ,z "p ( ! ,initiative1 ! ,secret>y ( ,agriculture %all-- 7#a7 support rese>* & developm5t 9 eng9e]+ biology1 includ+ 9 syn!tic biology & biomat]ials2 7#b7 aw>d grants ?r\gh ! ,national ,in/itute ( ,food & ,agriculture & ! ,agriculture ,advanc$ ,rese>* & ,developm5t ,au?ority2 & 7#c7 support developm5t conduct$ by ! ,agricultural ,rese>* ,s]vice4 7f7 ,environm5tal ,protection ,ag5cy ,z "p ( ! ,initiative1 ! ,environm5tal ,protection ,ag5cy %all support rese>* on h[ products1 processes1 & sy/ems ( eng9e]+ biology w affect or c protect ! environm5t4 7g7 ,dep>tm5t ( ,heal? & ,human ,s]vices ,z "p ( ! ,initiative1 ! ,secret>y ( ,heal? & ,human ,s]vices1 z appropriate & consi/5t ) activities ( ! ,dep>tm5t ( ,heal? & ,human ,s]vices 9 effect on ! day be=e ! date ( ! enactm5t ( ?is ,act1 %all-- 7#a7 support rese>* & developm5t to advance ! und]/&+ & application ( eng9e]+ biology = human heal?2 7#b7 support relevant int]discipl9>y rese>* & coord9ation2 & 7#c7 support activities necess>y to facilitate ov]sight ( relevant em]g+ biote*nologies4 #i4 ,rule ( con/ruction ,no?+ 9 ?is ,act %all be con/ru$ to require public disclosure ( in=mation t is exempt f m&atory disclosure "u section #eeb ( title #e1 ,unit$ ,/ates ,code4 ,janu>y #bh1 #bjbb,report$ f ! ,committee on ,sci5ce1 ,space1 & ,te*nology ) an amendment,january #bh1 #bjbb;,committees on ,agriculture & ,en]gy & ,comm]ce dis*>g$2 committ$ to ! ,committee ( ! ,:ole ,h\se on ! ,/ate ( ! ,union & ord]$ to be pr9t$