,i  #aag? ,,congress  #a/ ,session  ,h4 
,r4 #befe  ,,9 ,,! ,,h\se ,,(           
,,repres5tatives  ,april #ae1 #bjba,mr4 
,bu*anan 7= himself1 ,mrs4 ,luria1 ,ms4 
,mace1 ,ms4 ,%]rill1 & ,mr4 ,br5dan ,f4 
,boyle ( ,p5nsylvania7 introduc$ !      
foll[+ bill2 :i* 0 ref]r$ to !          
,committee on ,en]gy & ,comm]ce  ,a     
,,bill  ,to am5d ! ,f$]al ,food1 ,drug1 
& ,cosmetic ,act to all[ manufactur]s & 
sponsors ( a drug to use alt]native te/+
 me?ods to animal te/+ to inve/igate !  
safety & effectiv5ess ( a drug1 & = o!r 
purposes4  #a4 ,%ort title ,?is ,act may
 be cit$ z ! ,,fda ,mod]nization ,act ( 
#bjba4  #b4 ,animal te/+ alt]natives    
,section #eje ( ! ,f$]al ,food1 ,drug1 &
 ,cosmetic ,act 7#ba ,u4,s4,c4 #cee7 is 
am5d$-- 7#a7 9 subsection               
7b77#e77;,b77i77,,ii71 by /rik+ animal &
 ins]t+ noncl9ical te/s or /udies2  7#b7
 9 subsection 7i7-- 7,a7 9 p>agraph     
7#a77;,a71 by /rik+ 7includ+ te/s on    
animals72 &  7,b7 9 p>agraph 7#b77;,b71 
by /rik+ animal or human /udies & ins]t+

 noncl9ical te/s or /udies2 &  7#c7 aft]
 subsection 7y71 by ins]t+ ! foll[+3    
7z7 ,noncl9ical te/ or /udy def9$ ,=    
purposes ( ?is section1 ! t]m noncl9ical
 te/ or /udy means a te/ or /udy t is   
mo/ likely to pr$ict human response bas$
 on sci5tific evid5ce & occurs be=e or  
dur+ ! cl9ical trial phase ( !          
inve/igation ( ! safety & effectiv5ess (
 a drug4 ,su* te/ or /udy may include ! 
foll[+3 7#a7 ,cell-bas$ assays4  7#b7   
,organ *ips & microphysiological sy/ems4
  7#c7 ,sophi/icat$ comput] model+4     
7#d7 ,o!r human biology-bas$ te/ me?ods4
  7#e7 ,animal te/s4  4