#aaf? ,,congress  #a/ ,session  ,9 !    
,h\se ( ,repres5tatives1 ,u4 ,s41       
,febru>y #be1 #bjai  ,,am5dm5t3  ,t !   
bill f ! ,s5ate 7,s4 #dhc7 entitl$ ,an  
,act to enact into law a bill by        
ref]5ce41 d pass ) ! foll[+ ,/rike out  
all aft] ! enact+ clause & ins]t3  #a4  
,%ort title2 table ( cont5ts  7a7 ,%ort 
title ,?is ,act may be cit$ z !         
,pe/icide ,regi/ration ,improvem5t      
,ext5sion ,act ( #bjah4  7b7 ,table (   
cont5ts ,! table ( cont5ts = ?is ,act is
 z foll[s3  ,sec4 #a4 ,%ort title2 table
 ( cont5ts4 ,sec4 #b4 ,ext5sion &       
modification ( ma9t5ance fee au?ority4  
,sec4 #c4 ,r]egi/ration & ,exp$it$      
,process+ ,fund4 ,sec4 #d4 ,exp]im5tal  
use p]mits = pe/icides4 ,sec4 #e4       
,pe/icide regi/ration s]vice fees4 ,sec4
 #f4 ,revision ( tables reg>d+ cov]$    
pe/icide regi/ration applications & o!r 
cov]$ actions & _! correspond+          
regi/ration s]vice fees4 ,sec4 #g4      
,agricultural work] protection /&>d2    
c]tification ( pe/icide applicators4    

#b4 ,ext5sion & modification ( ma9t5ance
 fee au?ority  7a7 ,ma9t5ance fee       
,section #d7;i77#a7 ( ! ,f$]al          
,insecticide1 ,fungicide1 & ,rod5ticide 
,act 7#g ,u4,s4,c4 #acf;a-#a7;i77#a77 is
 am5d$-- 7#a7 9 subp>agraph 7,c71 by    
/rik+ an aggregate am\nt ( #bg1hjj1jjj =
 ea* ( fiscal ye>s #bjac ?r\gh #bjag &  
ins]t+ an av]age am\nt ( #ca1jjj1jjj =  
ea* ( fiscal ye>s #bjai ?r\gh #bjbc2    
7#b7 9 subp>agraph 7,d7-- 7,a7 9 clause 
7i71 by /rik+ #aae1ejj = ea* ( fiscal   
ye>s #bjac ?r\gh #bjag & ins]t+ #abi1djj
 = ea* ( fiscal ye>s #bjai ?r\gh #bjbc2 
&  7,b7 9 clause 7ii71 by /rik+ #ahd1hjj
 = ea* ( fiscal ye>s #bjac ?r\gh #bjag &
 ins]t+ #bjg1jjj = ea* ( fiscal ye>s    
#bjai ?r\gh #bjbc2  7#c7 9 subp>agraph  
7,e77i7--  7,a7 9 subclause 7,i71 by    
/rik+ #gj1fjj = ea* ( fiscal ye>s #bjac 
?r\gh #bjag & ins]t+ #gi1ajj = ea* (    
fiscal ye>s #bjai ?r\gh #bjbc2 &  7,b7 9
 subclause 7,,ii71 by /rik+ #abb1ajj =  
ea* ( fiscal ye>s #bjac ?r\gh #bjag &   
ins]t+ #acf1hjj = ea* ( fiscal ye>s     

#bjai ?r\gh #bjbc2 &  7#d7 9 subp>agraph
 7,i71 by /rik+ #bjag44 & ins]t+ #bjbc44
  7b7 ,prohibition on o!r fees ,section 
#d7;i77#b7 ( ! ,f$]al ,insecticide1     
,fungicide1 & ,rod5ticide ,act 7#g      
,u4,s4,c4 #acf;a-#a7;i77#b77 is am5d$-- 
7#a7 by /rik+ ! date ( enactm5t ( ?is   
section & end+ on ,septemb] #cj1 #bjai &
 ins]t+ ! effective date ( ! ,pe/icide  
,regi/ration ,improvem5t ,ext5sion ,act 
( #bjah & end+ on ,septemb] #cj1 #bjbe2 
&  7#b7 by ins]t+ aft] regi/ration ( a  
pe/icide "u ?is ,act ! foll[+3 or any   
o!r action cov]$ "u a table specifi$ 9  
section #cc7;b77#c714  7c7 ,ext5sion (  
prohibition on tol]ance fees ,section   
#djh7m77#c7 ( ! ,f$]al ,food1 ,drug1 &  
,cosmetic ,act 7#ba ,u4,s4,c4           
#cdf;a7m77#c77 is am5d$ by /rik+ #bjag &
 ins]t+ #bjbc4  #c4 ,r]egi/ration &     
,exp$it$ ,process+ ,fund  7a7 ,au?oriz$ 
use ( fund ,section #d7k77#b77;,a7 ( !  
,f$]al ,insecticide1 ,fungicide1 &      
,rod5ticide ,act 7#g ,u4,s4,c4          
#acf;a-#a7k77#b77;,a77 is am5d$--  7#a7 

9 ! fir/ s5t5ce1 by /rik+ ! fund &      
ins]t+ ! ,r]egi/ration & ,exp$it$       
,process+ ,fund2  7#b7 by /rik+ p>agraph
 7#c71 9 ! fir/ s5t5ce & all t foll[s   
?r\gh ! p]iod at ! end ( ! second s5t5ce
 & ins]t+ ! foll[+3 p>agraph 7#c71 to   
(fset ! co/s ( regi/ration review "u    
section #c7;g71 includ+ ! co/s associat$
 ) any review "u ! ,endang]$ ,species   
,act ( #aigc 7#af ,u4,s4,c4 #aeca et    
seq47 requir$ z "p ( ! regi/ration      
review1 to (fset ! co/s associat$ )     
track+ & implem5t+ regi/ration review   
decisions1 includ+ regi/ration review   
decisions design$ to r$uce risk1 = !    
purposes specifi$ 9 p>agraphs 7#d7 &    
7#e71 & to enhance ! in=mation sy/ems   
capabilities to improve ! track+ (      
pe/icide regi/ration decisions42  7#c7 9
 clause 7i71 by /rik+ are allocat$      
solely & all t foll[s ?r\gh #c7;g72 &   
ins]t+ ! foll[+3 are allocat$ solely = !
 purposes specifi$ 9 ! fir/ s5t5ce ( ?is
 subp>agraph22 &  7#d7 9 clause 7ii71 by
 /rik+ necess>y to a*ieve & all t foll[s

 ?r\gh #c7;g72 & ins]t+ ! foll[+3       
necess>y to a*ieve ! purposes specifi$ 9
 ! fir/ s5t5ce ( ?is subp>agraph24  7b7 
,set-,aside = review ( in]t +r$i5ts &   
exp$it$ process+ ( simil> applications  
,section #d7k77#c77;,a7 ( ! ,f$]al      
,insecticide1 ,fungicide1 & ,rod5ticide 
,act 7#g ,u4,s4,c4                      
#acf;a-#a7k77#c77;,a77 is am5d$1 9 !    
matt] prec$+ clause 7i71 by /rik+ ,!    
,adm9i/rator %all use & all t foll[s    
?r\gh p]sonnel & res\rces-- & ins]t+ !  
foll[+3 ,= ea* ( fiscal ye>s #bjah ?r\gh
 #bjbc1 ! ,adm9i/rator %all use betwe5  
#a_/i & #a_/h ( ! ma9t5ance fees        
collect$ 9 su* fiscal ye> to obta9      
suffici5t p]sonnel & res\rces--4  7c7   
,set-,aside = ,exp$it$ ,rulemak+ &      
,guidance ,developm5t = c]ta9 purposes  
,p>agraph 7#d7 ( section #d7k7 ( !      
,f$]al ,insecticide1 ,fungicide1 &      
,rod5ticide ,act 7#g ,u4,s4,c4          
#acf;a-#a7k77 is am5d$ to read z foll[s3
  7#d7 ,exp$it$ rulemak+ & guidance     
developm5t = c]ta9 product p]=mance data

 requirem5ts  7,a7 ,set-aside ,= ea* (  
fiscal ye>s #bjah ?r\gh #bjbc1 !        
,adm9i/rator %all use n m ?an #ejj1jjj (
 ! am\nts made available to !           
,adm9i/rator 9 ! ,r]egi/ration &        
,exp$it$ ,process+ ,fund = ! activities 
describ$ 9 subp>agraph 7,b74  7,b7      
,products claim+ efficacy aga9/         
inv]tebrate pe/s ( significant public   
heal? or economic importance ,!         
,adm9i/rator %all use am\nts made       
available "u subp>agraph 7,a7 to        
develop1 receive comm5ts ) respect to1  
f9alize1 & implem5t ! necess>y rulemak+ 
& guidance = product p]=mance data      
requirem5ts to evaluate products claim+ 
efficacy aga9/ ! foll[+ inv]tebrate pe/s
 ( significant public heal? or economic 
importance 79 ord] ( importance73  7i7  
,b$ bugs4  7ii7 ,premise 7includ+ crawl+
 insects1 fly+ insects1 & baits74  7iii7
 ,pe/s ( pets 7includ+ pet pe/s         
controll$ by spot-ons1 coll>s1 %ampoos1 
p[d]s1 or dips74  7iv7 ,fire ants4  7,c7
 ,deadl9es = guidance ,! ,adm9i/rator   

%all develop1 & publi% guidance requir$ 
by subp>agraph 7,b71 ) respect to claims
 ( efficacy aga9/ pe/s describ$ 9 su*   
subp>agraph z foll[s3 7i7 ,) respect to 
b$ bugs1 issue f9al guidance n lat] ?an 
#cj days aft] ! effective date ( !      
,pe/icide ,regi/ration ,improvem5t      
,ext5sion ,act ( #bjah4  7ii7 ,) respect
 to pe/s specifi$ 9 clause 7ii7 ( su*   
subp>agraph-- 7,i7 submit draft guidance
 to ! ,sci5tific ,advisory ,panel & =   
public comm5t n lat] ?an ,june #cj1     
#bjah2 &  7,,ii7 complete any response  
to comm5ts receiv$ ) respect to su*     
draft guidance & f9alize ! guidance n   
lat] ?an ,septemb] #cj1 #bjai4  7iii7 ,)
 respect to pe/s specifi$ 9 clauses     
7iii7 & 7iv7 ( su* subp>agraph--  7,i7  
submit draft guidance to ! ,sci5tific   
,advisory ,panel & = public comm5t n    
lat] ?an ,june #cj1 #bjai2 &  7,,ii7    
complete any response to comm5ts receiv$
 ) respect to su* draft guidance &      
f9alize ! guidance n lat] ?an ,m>* #ca1 
#bjba4  7,d7 ,revision ,! ,adm9i/rator  

%all revise ! guidance requir$ by       
subp>agraph 7,b7 f "t to "t1 b %all     
p]mit applicants & regi/rants suffici5t 
"t to obta9 data t meet ! requirem5ts   
specifi$ 9 su* revis$ guidance4  7,e7   
,deadl9e = product p]=mance data        
requirem5ts ,! ,adm9i/rator %all1 n lat]
 ?an ,septemb] #cj1 #bjba1 issue        
regulations prescrib+ product p]=mance  
data requirem5ts = any pe/icide int5d$ =
 prev5t+1 de/roy+1 repell+1 or mitigat+ 
any inv]tebrate pe/ ( significant public
 heal? or economic importance specifi$ 9
 clauses 7i7 ?r\gh 7iv7 ( subp>agraph   
7,b74  4  7d7 ,set-,aside = ,good       
laboratory practices inspections        
,section #d7k7 ( ! ,f$]al ,insecticide1 
,fungicide1 & ,rod5ticide ,act 7#g      
,u4,s4,c4 #acf;a-#a7k77 is am5d$-- 7#a7 
by r$esignat+ p>agraphs 7#e7 & 7#f7 z   
p>agraphs 7#f7 & 7#g71 respectively2    
7#b7 by ins]t+ aft] p>agraph 7#d7 !     
foll[+ new p>agraph3  7#e7 ,good        
laboratory practices inspections  7,a7  
,set-aside ,= ea* ( fiscal ye>s #bjah   

?r\gh #bjbc1 ! ,adm9i/rator %all use n m
 ?an #ejj1jjj ( ! am\nts made available 
to ! ,adm9i/rator 9 ! ,r]egi/ration &   
,exp$it$ ,process+ ,fund = ! activities 
describ$ 9 subp>agraph 7,b74  7,b7      
,activities ,! ,adm9i/rator %all use    
am\nts made available "u subp>agraph    
7,a7 = enhancem5ts to ! good laboratory 
practices /&>ds compliance monitor+     
program e/abli%$ "u "p #afj ( title #dj 
( ! ,code ( ,f$]al ,regulations 7or     
successor regulations71 ) respect to    
laboratory inspections & data audits    
conduct$ 9 support ( pe/icide product   
regi/rations "u ?is ,act4 ,z "p ( su*   
monitor+ program1 ! ,adm9i/rator %all   
make available to ea* laboratory        
inspect$ "u su* program 9 support ( su* 
regi/rations a prelim9>y summ>y (       
inspection obs]vations n lat] ?an #fj   
days aft] ! date on :i* su* an          
inspection is complet$4  2 &  7#c7 9    
p>agraph 7#g71 z s r$esignat$1 by /rik+ 
p>agraphs 7#b71 7#c71 & 7#d7 & ins]t+   
p>agraphs 7#b71 7#c71 7#d71 & 7#e74  #d4

 ,exp]im5tal use p]mits = pe/icides     
,section #e7;a7 ( ! ,f$]al ,insecticide1
 ,fungicide1 & ,rod5ticide ,act 7#g     
,u4,s4,c4 #acf;c7a77 is am5d$-- 7#a7 by 
/rik+ p]mit = a pe/icide4 & ins]t+ p]mit
 = a pe/icide4 ,an application = an     
exp]im5tal use p]mit = a cov]$          
application "u section #cc7;b7 %all     
con=m ) ! requirem5ts ( t section42 &   
7#b7 by ins]t+ 7or 9 ! case ( an        
application = an exp]im5tal use p]mit = 
a cov]$ application "u section #cc7;b71 
n lat] ?an ! la/ day ( ! applicable     
timeframe = su* application specifi$ 9  
su* section7 aft] all requir$ support+  
data4  #e4 ,pe/icide regi/ration s]vice 
fees  7a7 ,ext5sion & modification ( fee
 au?ority ,section #cc7;b7 ( ! ,f$]al   
,insecticide1 ,fungicide1 & ,rod5ticide 
,act 7#g ,u4,s4,c4 #acfw-#h7;b77 is     
am5d$--  7#a7 9 p>agraph 7#b7-- 7,a7 9 !
 head+1 by /rik+ pe/icide regi/ration2 &
  7,b7 9 subp>agraph 7,a71 by ins]t+ or 
= any o!r action cov]$ by a table       
specifi$ 9 p>agraph 7#c7 aft] cov]$ by  

?is ,act t is receiv$ by ! ,adm9i/rator 
on or aft] ! effective date ( !         
,pe/icide ,regi/ration ,improvem5t ,act 
( #bjjc2  7#b7 9 p>agraph 7#e7--  7,a7 9
 ! head+1 by /rik+ pe/icide regi/ration 
applications & ins]t+ cov]$             
applications2 &  7,b7 by /rik+ pe/icide 
regi/ration application bo? places x    
appe>s & ins]t+ cov]$ application2  7#c7
 9 p>agraph 7#f7-- 7,a7 9 subp>agraph   
7,a7--  7i7 by /rik+ pe/icide           
regi/ration2 &  7ii7 by /rik+ ,octob]   
#a1 #bjac1 & end+ on ,septemb] #cj1     
#bjae & ins]t+ ,octob] #a1 #bjai1 & end+
 on ,septemb] #cj1 #bjba2  7,b7 9       
subp>agraph 7,b7-- 7i7 by /rik+ pe/icide
 regi/ration2 &  7ii7 by /rik+ #bjae ea*
 place x appe>s & ins]t+ #bjba2 &  7,c7 
9 subp>agraph 7,c71 by /rik+ revis$     
regi/ration s]vice fee s*$ules & ins]t+ 
s]vice fee s*$ules revis$ pursuant to   
?is p>agraph2  7#d7 9 p>agraph 7#g7--   
7,a7 9 subp>agraph 7,a7--  7i7 by /rik+ 
cov]$ pe/icide regi/ration & ins]t+     
cov]$ application2 &  7ii7 by ins]t+    

be=e ! p]iod at ! end ! foll[+3 1 except
 t no waiv] or fee r$uction %all be     
provid$ 9 connection ) a reque/ = a     
lett] ( c]tification 7commonly ref]r$ to
 z a ,gold ,seal lett]72 &  7,b7 9      
subp>agraph 7,f77i71 by /rik+ pe/icide  
regi/ration2 &  7#e7 9 p>agraph 7#h7--  
7,a7 9 subp>agraph 7,a71 by /rik+       
pe/icide regi/ration2  7,b7 9           
subp>agraph 7,b77i71 by /rik+ pe/icide  
regi/ration2 &  7,c7 9 subp>agraph      
7,c7-- 7i7 9 clause 7i71 by /rik+       
pe/icide regi/ration & ins]t+ cov]$2 &  
7ii7 9 clause 7ii77,i71 by /rik+        
pe/icide regi/ration & ins]t+ cov]$4    
7b7 ,pe/icide regi/ration fund          
set-,asides = work] protection1 p>tn]%ip
 grants1 & pe/icide safety education    
,section #cc7;c77#c77;,b7 ( ! ,f$]al    
,insecticide1 ,fungicide1 & ,rod5ticide 
,act 7#g ,u4,s4,c4                      
#acfw-#h7;c77#c77;,b77 is am5d$--  7#a7 
9 ! head+1 by ins]t+ 1 p>tn]%ip grants1 
& pe/icide safety education aft] ,work] 
protection2  7#b7 9 clause 7i7--  7,a7  

by /rik+ #bjag & ins]t+ #bjbc2 &  7,b7  
by ins]t+ be=e ! p]iod at ! end !       
foll[+31 ) an emphasis on field-work]   
populations 9 ! ,unit$ ,/ates2  7#c7 9  
clause 7ii71 by /rik+ #bjag & ins]t+    
#bjbc2 &  7#d7 9 clause 7iii71 by /rik+ 
#bjag & ins]t+ #bjbc4  7c7 ,re=ms ,to   
r$uce decision "t review p]iods ,section
 #cc7;e7 ( ! ,f$]al ,insecticide1       
,fungicide1 & ,rod5ticide ,act 7#g      
,u4,s4,c4 #acfw-#h7;e77 is am5d$-- 7#a7 
by /rik+ ,pe/icide ,regi/ration         
,improvem5t ,ext5sion ,act ( #bjab &    
ins]t+ ,pe/icide ,regi/ration           
,improvem5t ,ext5sion ,act ( #bjah2 &   
7#b7 by ins]t+ at ! end ! foll[+ new    
s5t5ce3 ,su* re=ms %all include id5tify+
 opportunities = /reaml9+ review        
processes = applications = a new active 
+r$i5t or a new use & provid+ prompt    
fe$back to applicants dur+ su* review   
process44  7d7 ,decision "t review      
p]iods ,section #cc7;f7 ( ! ,f$]al      
,insecticide1 ,fungicide1 & ,rod5ticide 
,act 7#g ,u4,s4,c4 #acfw-#h7;f77 is     

am5d$--  7#a7 9 p>agraph 7#a7-- 7,a7 by 
/rik+ ,pe/icide ,regi/ration ,improvem5t
 ,ext5sion ,act ( #bjab & ins]t+        
,pe/icide ,regi/ration ,improvem5t      
,ext5sion ,act ( #bjah2 &  7,b7 by      
ins]t+ aft] cov]$ pe/icide regi/ration  
actions ! foll[+3 or = any o!r action   
cov]$ by a table specifi$ 9 subsection  
7b77#c72  7#b7 9 p>agraph 7#c71 by /rik+
 subp>agraph 7,c7 & ins]t+ ! foll[+ new 
subp>agraph3  7,c7 applications = any   
o!r action cov]$ by a table specifi$ 9  
subsection 7b77#c74  2 &  7#c7 9        
p>agraph 7#d77;,a7--  7,a7 by /rik+ a   
pe/icide regi/ration application &      
ins]t+ a cov]$ application2 &  7,b7 by  
/rik+ cov]$ pe/icide regi/ration        
application & ins]t+ cov]$ application4 
7e7 ,report+ requirem5ts ,section #cc7k7
 ( ! ,f$]al ,insecticide1 ,fungicide1 & 
,rod5ticide ,act 7#g ,u4,s4,c4          
#acfw-#h7k77 is am5d$-- 7#a7 9 p>agraph 
7#a7 by /rik+ #bjag & ins]t+ #bjbc2 &   
7#b7 9 p>agraph 7#b7-- 7,a7 9           
subp>agraph 7,d71 by /rik+ clause 7i7 & 

ins]t+ ! foll[+ new clause3  7i7 ! numb]
 ( pe/icides or pe/icide cases review$ &
 ! numb] ( regi/ration review decisions 
complet$1 includ+-- 7,i7 ! numb] ( cases
 cancell$2  7,,ii7 ! numb] ( cases      
requir+ risk mitigation measures2       
7,,iii7 ! numb] ( cases remov+ risk     
mitigation measures2  7,,iv7 ! numb] (  
cases ) no risk mitigation ne$$2 &  7,v7
 ! numb] ( cases 9 :i* risk mitigation  
has be5 fully implem5t$2  2  7,b7 9     
subp>agraph 7,g7-- 7i7 9 clause 7i7--   
7,i7 by /rik+ section #d7k77#d7 & ins]t+
 p>agraphs 7#d7 & 7#e7 ( section #d7k72 
&  7,,ii7 by /rik+ t section & ins]t+   
su* p>agraphs2  7ii7 by /rik+ clauses   
7ii71 7iii71 7iv71 7v71 & 7vi72  7iii7  
by ins]t+ aft] clause 7i7 ! foll[+ new  
clause3  7ii7 implem5t+ enhancem5ts to--
 7,i7 ! electronic track+ ( cov]$       
applications2  7,,ii7 ! electronic      
track+ ( conditional regi/rations2      
7,,iii7 ! endang]$ species database2    
7,,iv7 ! electronic review ( labels     
submitt$ ) cov]$ applications2 &  7,v7 !

 electronic review & assessm5t (        
confid5tial /atem5ts ( =mula submitt$ ) 
cov]$ applications2 &  2 &  7iv7 by     
r$esignat+ clause 7vii7 z clause 7iii72 
7,c7 9 subp>agraph 7,i71 by /rik+ & at !
 end2  7,d7 9 subp>agraph 7,j71 by /rik+
 ! p]iod at ! end & ins]t+ a semicolon2 
&  7,e7 by add+ at ! end ! foll[+ new   
subp>agraphs3  7,k7 a review ( !        
progress made 9 develop+1 updat+1 &     
implem5t+ product p]=mance te/ guidel9es
 = pe/icide products t are int5d$ to    
control inv]tebrate pe/s ( significant  
public heal? importance &1 by           
regulation1 prescrib+ product p]=mance  
data requirem5ts = su* pe/icide products
 regi/]$ "u section #c2  7,l7 a review (
 ! progress made 9 ! priority review &  
approval ( new pe/icides to control     
inv]tebrate public heal? pe/s t may     
transmit vector-borne disease = use 9 ! 
,unit$ ,/ates1 includ+ ea* t]ritory or  
possession ( ! ,unit$ ,/ates1 & ,unit$  
,/ates milit>y in/allations globally2   
7,m7 a review ( ! progress made 9       

implem5t+ enhancem5ts to ! good         
laboratory practices /&>ds compliance   
monitor+ program e/abli%$ "u "p #afj (  
title #dj ( ! ,code ( ,f$]al            
,regulations 7or successor regulations72
  7,n7 ! numb] ( approvals = active     
+r$i5ts1 new uses1 & pe/icide end use   
products grant$ 9 connection ) ! ,design
 = ! ,environm5t program 7or any        
successor program7 ( ! ,environm5tal    
,protection ,ag5cy2 &  7,o7 ) respect to
 funds 9 ! ,pe/icide ,regi/ration ,fund 
res]v$ "u subsection 7c77#c71 a review t
 includes-- 7i7 a description ( ! am\nt 
& use ( su* funds--  7,i7 to c>ry out   
activities relat+ to work] protection "u
 clause 7i7 ( subsection 7c77#c77;,b72  
7,,ii7 to aw>d p>tn]%ip grants "u clause
 7ii7 ( su* subsection2 &  7,,iii7 to   
c>ry out ! pe/icide safety education    
program "u clause 7iii7 ( su*           
subsection2  7ii7 an evaluation ( !     
appropriat5ess & effectiv5ess ( !       
activities1 grants1 & program describ$ 9
 clause 7i72  7iii7 a description ( h[  

/akehold]s are engag$ 9 ! decision to   
fund su* activities1 grants1 & program2 
&  7iv7 ) respect to activities relat+  
to work] protection c>ri$ out "u        
subp>agraph 7,b77i7 ( su* subsection1 a 
summ>y ( ! analyses f /akehold]s1       
includ+ f work] community-bas$          
organizations1 on ! appropriat5ess &    
effectiv5ess ( su* activities4  4  7f7  
,t]m9ation ( effectiv5ess ,section      
#cc7m7 ( ! ,f$]al ,insecticide1         
,fungicide1 & ,rod5ticide ,act 7#g      
,u4,s4,c4 #acfw-#h7m77 is am5d$-- 7#a7 9
 p>agraph 7#a71 by /rik+ #bjag & ins]t+ 
#bjbc2 &  7#b7 9 p>agraph 7#b7-- 7,a7 9 
subp>agraph 7,a7--  7i7 by /rik+ ,fiscal
 ye> #bjah4--;,dur+ fiscal ye> #bjah &  
ins]t+ ,fiscal ye> #bjbd4--;,dur+ fiscal
 ye> #bjbd2 &  7ii7 by /rik+ #bjag &    
ins]t+ #bjbc2  7,b7 9 subp>agraph 7,b7--
 7i7 by /rik+ ,fiscal ye> #bjai4--;,dur+
 fiscal ye> #bjai & ins]t+ ,fiscal ye>  
#bjbe4--;,dur+ fiscal ye> #bjbe2 &  7ii7
 by /rik+ #bjag & ins]t+ #bjbc2  7,c7 9 
subp>agraph 7,c71 by /rik+ ,septemb]    

#cj1 #bjai4--;,effective ,septemb] #cj1 
#bjai & ins]t+ ,septemb] #cj1           
#bjbe4--;,effective ,septemb] #cj1      
#bjbe2 &  7,d7 9 subp>agraph 7,d71 by   
/rik+ #bjag bo? places x appe>s & ins]t+
 #bjbc4  #f4 ,revision ( tables reg>d+  
cov]$ pe/icide regi/ration applications 
& o!r cov]$ actions & _! correspond+    
regi/ration s]vice fees ,p>agraph 7#c7 (
 section #cc7;b7 ( ! ,f$]al             
,insecticide1 ,fungicide1 & ,rod5ticide 
,act 7#g ,u4,s4,c4 #acfw-#h7;b77 is     
am5d$ to read z foll[s3  7#c7 ,s*$ule ( 
cov]$ applications & o!r actions & _!   
regi/ration s]vice fees ,subject to     
p>agraph 7#f71 ! s*$ule ( regi/ration   
applications & o!r cov]$ actions & _!   
correspond+ regi/ration s]vice fees %all
 be z foll[s3 ,,table #a4 --            
,,regi/ration ,,division -- ,,new       
,,active ,,+r$i5ts ,,epa ,no4,new ,,cr  
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
77 7#a7 ,a decision review "t t w\ld    
o!rwise end on a ,saturday1 ,sunday1 or 

f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day4 7#b7 ,all reque/s =   
new uses 7food &_/or nonfood7 conta9$ 9 
any application = a new active +r$i5t or
 a fir/ food use are cov]$ by ! base fee
 = t new active +r$i5t or fir/ food use 
application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   
fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 

ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application4 7#c7 ,:]e ! action involves
 approval ( a new or am5d$ label1 on or 
be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 

made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     
support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  

to ! ,ag5cy4 ,r#jaja,new ,active        
,+r$i5t1 ,food use4 7#b77c7bd #gec1jhb  
,r#jbjb,new ,active ,+r$i5t1 ,food use2 
r$uc$ risk4 7#b77c7ahfbg1efh ,r#jdjc,new
 ,active ,+r$i5t1 ,food use2 ,exp]im5tal
 ,use ,p]mit application2 e/abli%       
tempor>y tol]ance2 submitt$ be=e        
application = regi/ration2 cr$it #de (  
fee t[>d new active +r$i5t application t
 foll[s4 7#c7ahdfb1ejb ,r#jfjd,new      
,active ,+r$i5t1 ,non-food use2 outdoor4
 7#b77c7ba #ebc1bje ,r#jgje,new ,active 
,+r$i5t1 ,non-food use2 outdoor2 r$uc$  
risk4 7#b77c7afdcf1jjd ,r#jijf,new      
,active ,+r$i5t1 ,non-food use2 outdoor2
 ,exp]im5tal ,use ,p]mit application2   
submitt$ be=e application = regi/ration2
 cr$it #de ( fee t[>d new active +r$i5t 
application t foll[s4 7#c7afcbc1fij     
,r#aajg,new ,active ,+r$i5t1 ,non-food  
use2 indoor4 7#b77c7bjbij1iid           
,r#abjh,new ,active ,+r$i5t1 ,non-food  
use2 indoor2 r$uc$ risk4                
7#b77c7adbdb1die ,r#abai,new ,active    
,+r$i5t1 ,non-food use2 indoor2         

,exp]im5tal ,use ,p]mit application2    
submitt$ be=e application = regi/ration2
 cr$it #de ( fee t[>d new active +r$i5t 
application t foll[s4 7#c7ahahb1cbg     
,r#abbaj;,enri*$ isom]7s7 ( regi/]$     
mix$-isom] active +r$i5t4               
7#b77c7ahcag1abh ,r#abcaa,new ,active   
,+r$i5t1 ,se$ treatm5t only2 includes   
agricultural & non-agricultural se$s2   
residues n expect$ 9 raw agricultural   
commodities4 7#b77c7ahdga1hfa           
,r#abeab,new ,active ,+r$i5t1 ,se$      
treatm5t2 ,exp]im5tal ,use ,p]mit       
application2 submitt$ be=e application =
 regi/ration2 cr$it #de ( fee t[>d new  
active +r$i5t application t foll[s4     
7#c7afcbc1fij ,,table #b4 --            
,,regi/ration ,,division -- ,,new ,,uses
 ,,epa ,no4,new ,,cr                    
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
77 7#a7 ,a decision review "t t w\ld    
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day4 7#b7 ,all reque/s =   

new uses 7food &_/or nonfood7 conta9$ 9 
any application = a new active +r$i5t or
 a fir/ food use are cov]$ by ! base fee
 = t new active +r$i5t or fir/ food use 
application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   
fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+

 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application4 7#c7 ,:]e ! action involves
 approval ( a new or am5d$ label1 on or 
be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 
made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     

support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 7#d7 ,am5dm5t applications 
to add ! new use7s7 to regi/]$ product  

labels are cov]$ by ! base fee = ! new  
use7s74 ,all items 9 ! cov]$ application
 mu/ be submitt$ toge!r 9 "o package4   
,ea* application = an additional new    
product regi/ration & new in]t          
approval7s7 t is submitt$ 9 ! new use   
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,h[ev]1 if a new
 use application only proposes to regi/]
 ! new use = a new product & !re are no 
am5dm5ts 9 ! application1 !n review ( "o
 new product application is cov]$ by !  
new use fee4 ,all su* associat$         
applications t are submitt$ toge!r w be 
subject to ! new use decision review "t4
 ,any application = a new product or an 
am5dm5t to ! propos$ label+ 7a7 submitt$
 subsequ5t to submission ( ! new use    
application & 7b7 prior to conclusion ( 
its decision review "t & 7c7 conta9+ !  
same new uses1 w be deem$ a sep>ate     
new-use application1 subject to a       
sep>ate regi/ration s]vice fee & new    
decision review "t = a new use4 ,if !   

new-use application includes non-food   
7indoor &_/or outdoor71 & food 7outdoor 
&_/or indoor7 uses1 ! appropriate fee is
 due = ea* type ( new use & ! longe/    
decision review "t applies to all ( !   
new uses reque/$ 9 ! application4 ,any  
in=mation t 7a7 0 nei!r reque/$ nor     
requir$ by ! ,ag5cy1 & 7b7 is submitt$  
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre51 & 7c7 is n itself a cov]$        
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new use application4 ,r#acjac;,fir/ food
 use2 indoor2 food_/food h&l+4 7#b7     
7#c7baaia1ddd ,r#adjad;,additional food 
use2 ,indoor2 food_/food h&l+4 7#c7     
7#d7aedd1fgb ,r#aejae;,fir/ food use4   
7#b77c7ba #cag1ajd ,r#aeeaf 7new7,fir/  
food use1 ,exp]im5tal ,use ,p]mit       
application2 a4i4 regi/]$ = non-food    
outdoor use4 7#c77d7babfd1bec           
,r#afjag;,fir/ food use2 r$uc$ risk4    
7#b77c7afbfd1bec ,r#agjah;,additional   

food use4 7#c7 7#d7aegi1cdi             
,r#ageai;,additional food uses cov]$ )9 
a crop gr\p result+ f ! conv]sion (     
exi/+ approv$ crop gr\p7s7 to "o or m   
revis$ crop gr\ps4 7#c77d7ajff1abd      
,r#ahjbj;,additional food use2 r$uc$    
risk4 7#c77d7ajff1abd                   
,r#aijba;,additional food uses2 #f or m 
submitt$ 9 "o application4              
7#c77d7aedgf1jij ,r#bjjbb;,additional   
,food ,use2 #f or m submitt$ 9 "o       
application2 ,r$uc$ ,risk4              
7#c77d7ajcif1gdb ,r#bajbc;,additional   
food use2 ,exp]im5tal ,use ,p]mit       
application2 e/abli% tempor>y tol]ance2 
no cr$it t[>d new use regi/ration4      
7#c77d7abdh1ihf ,r#bbjbd;,additional    
food use2 ,exp]im5tal ,use ,p]mit       
application2 crop de/ruct basis2 no     
cr$it t[>d new use regi/ration4         
7#c77d7fai1hch ,r#bcjbe;,additional use2
 non-food2 outdoor4 7#c7 7#d7aeca1gac   
,r#bdjbf;,additional use2 non-food2     
outdoor2 r$uc$ risk4 7#c77d7ajbf1dbg    
,r#bejbg;,additional use2 non-food2     

outdoor2 ,exp]im5tal ,use ,p]mit        
application2 no cr$it t[>d new use      
regi/ration4 7#c77d7fai1hch             
,r#beabh;,exp]im5tal ,use ,p]mit        
application :i* requires no *anges to ! 
tol]ance7s72 non-crop de/ruct basis4    
7#c7hai1hch ,r#bfjbi,new use2 non-food2 
indoor4 7#c7 7#d7abae1cag ,r#bgjcj,new  
use2 non-food2 indoor2 r$uc$ risk4      
7#c77d7iab1gfd ,r#bgaca,new use2        
non-food2 indoor2 ,exp]im5tal ,use      
,p]mit application2 no cr$it t[>d new   
use regi/ration4 7#c77d7fi1gbe          
,r#bgccb;,additional use2 se$ treatm5t2 
limit$ uptake into ,raw ,agricultural   
,commodities2 includes crops ) e/abli%$ 
tol]ances 7e4g41 = soil or foli>        
application72 includes food &_/or       
non-food uses4 7#c77d7abej1dde          
,r#bgdcc;,additional uses2 se$ treatm5t 
only2 #f or m submitt$ 9 "o application2
 limit$ uptake into raw agricultural    
commodities2 includes crops ) e/abli%$  
tol]ances 7e4g41 = soil or foli>        
application72 includes food &_/or       

non-food uses4 7#c77d7 #abcjb1ffc       
,,table #c4 -- ,,regi/ration ,,division 
-- ,,import ,,& ,,o!r ,,tol]ances ,,epa 
,no4,new ,,cr ,no4,action,decision      
,review ,"t 7,mon?s77#a7 ,regi/ration   
,s]vice ,fee 77 7#a7 ,a decision review 
"t t w\ld o!rwise end on a ,saturday1   
,sunday1 or f$]al holiday1 w be ext5d$  
to end on ! next bus9ess day4 7#b7 ,all 
reque/s = new uses 7food &_/or nonfood7 
conta9$ 9 any application = a new active
 +r$i5t or a fir/ food use are cov]$ by 
! base fee = t new active +r$i5t or fir/
 food use application & reta9 ! same    
decision "t review p]iod z ! new active 
+r$i5t or fir/ food use application4 ,! 
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  

or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 

#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application4 7#c7 ,:]e ! action involves
 approval ( a new or am5d$ label1 on or 
be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 
made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     
support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$

 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 7#d7 ,am5dm5t applications 
to add ! revis$ use patt]n7s7 to regi/]$
 product labels are cov]$ by ! base fee 
= ! category4 ,all items 9 ! cov]$      
application mu/ be submitt$ toge!r 9 "o 
package4 ,ea* application = an          
additional new product regi/ration & new
 in]t approval7s7 t is submitt$ 9 !     
am5dm5t application package is subject  
to ! regi/ration s]vice fee = a new     
product or a new in]t approval4 ,h[ev]1 
if an am5dm5t application only proposes 
to regi/] ! am5dm5t = a new product &   
!re are no am5dm5ts 9 ! application1 !n 
review ( "o new product application is  
cov]$ by ! base fee4 ,all su* associat$ 
applications t are submitt$ toge!r w be 
subject to ! category decision review   

"t4 ,r#bhjcd;,e/abli% import tol]ance2  
new active +r$i5t or fir/ food use4     
7#b7bacai1jgb ,r#bijce;,e/abli% ,import 
tol]ance2 ,additional new food          
use4#aefc1haf ,r#biacf;,e/abli% import  
tol]ances2 additional food uses2 #f or m
 crops submitt$ 9 "o petition4#aechb1hhf
 ,r#bibcg;,am5d an e/abli%$ tol]ance    
7e4g41 decrease or increase7 &_/or      
h>monize e/abli%$ tol]ances ) ,codex    
,m,r,ls2 dome/ic or import2             
applicant-initiat$4#aade1cda            
,r#bicch;,e/abli% tol]ance7s7 =         
inadv]t5t residues 9 "o crop2           
applicant-initiat$4#abec1dhc            
,r#bidci;,e/abli% tol]ances = inadv]t5t 
residues2 #f or m crops submitt$ 9 "o   
application2                            
applicant-initiat$4#abcbj1hid           
,r#biedj;,e/abli% tol]ance7s7 = residues
 9 "o rotational crop 9 response to a   
specific rotational crop application2   
submission ( correspond+ label am5dm5ts 
:i* specify ! necess>y plant-back       
re/rictions2 applicant-initiat$4 7#c7   

7#d7aeff1abd ,r#bifda;,e/abli% tol]ances
 = residues 9 rotational crops 9        
response to a specific rotational crop  
petition2 #f or m crops submitt$ 9 "o   
application2 submission ( correspond+   
label am5dm5ts :i* specify ! necess>y   
plant-back re/rictions2                 
applicant-initiat$4 7#c7 7#d7aecif1gdb  
,r#bigdb;,am5d #f or m e/abli%$         
tol]ances 7e4g41 decrease or increase7 9
 "o petition2 dome/ic or import2        
applicant-initiat$4#aabgb1jcg           
,r#bihdc;,am5d an e/abli%$ tol]ance     
7e4g41 decrease or increase72 dome/ic or
 import2 submission ( correspond+ am5d$ 
labels 7requir+ sci5ce review74 7#c7    
7#d7aceh1efe ,r#biidd;,am5d #f or m     
e/abli%$ tol]ances 7e4g41 decrease or   
increase72 dome/ic or import2 submission
 ( correspond+ am5d$ labels 7requir+    
sci5ce review74 7#c7 7#d7acbhe1bfa      
,,table #d4 -- ,,regi/ration ,,division 
-- ,,new ,,products ,,epa ,no4,new ,,cr 
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  

77 7#a7 ,a decision review "t t w\ld    
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day4 7#b7 ,an application =
 a new end-use product us+ a s\rce (    
active +r$i5t t 7a7 is n yet regi/]$ b  
7b7 has an application p5d+ ) ! ,ag5cy =
 review1 w be consid]$ an application = 
a new product ) an unregi/]$ s\rce (    
active +r$i5t4 7#c7 ,:]e ! action       
involves approval ( a new or am5d$      
label1 on or be=e ! end date ( !        
decision review "t1 ! ,ag5cy %all       
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  

resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 7#d7 ,= ! purposes (       
classify+ propos$ regi/ration actions   
into ,,pria categories1 8pe/7s7 requir+ 
efficacy0 are3 public heal? pe/s li/$ 9 
,,pr ,notice #bjjb-a1 live/ock pe/s     
7e4g4 ,horn flies1 ,/able flies71       
wood-de/roy+ pe/s 7e4g4 t]mites1 c>p5t] 
ants1 wood-bor+ beetles7 & c]ta9        
invasive species 7e4g4 ,asian ,longhorn$
 beetle1 ,em]ald ,a%bor]74 ,?is li/ may 
be updat$_/ref9$ z invasive pe/ ne$s    

arise4 ,to det]m9e ! numb] ( pe/s = !   
,,pria categories1 pe/s h be5 plac$ into
 gr\ps 7g5]al2 e4g41 cockroa*es7 & pe/  
specific 7specifically a te/ species74  
,if seek+ a label claim aga9/ a pe/ gr\p
 7g5]al71 use ! gr\p li/+ bel[ & ea*    
gr\p w c\nt z #a4 ,! g5]al pe/s gr\ps   
are3 mites1 du/ mites1 *igg]s1 ticks1   
h>d ticks1 s(t ticks1 cattle ticks1     
scorpions1 spid]s1 c5tip$es1 lice1      
fleas1 cockroa*es1 k$s1 bot flies1      
screwworms1 fil? flies1 bl[ flies1 h\se 
flies1 fle% flies1 mosquitoes1 bit+     
flies1 horse flies1 /able flies1 de]    
flies1 s& flies1 bit+ midges1 black     
flies1 true bugs1 b$ bugs1 /++ bees1    
wasps1 yell[ jackets1 hornets1 ants     
7exclud+ c>p5t] ants71 fire & h>ve/]    
ants1 wood de/roy+ beetles1 c>p5t] ants1
 t]mites1 subt]ranean t]mites1 dry wood 
t]mites1 arboreal t]mites1 damp wood    
t]mites & invasive species4 ,if seek+ a 
claim aga9/ a specific pe/ )\t a g5]al  
claim !n ea* specific pe/ w c\nt z #a4  
,r#cjjde,new product2 or simil>         

comb9ation product 7already regi/]$7 to 
an id5tical or sub/antially simil> 9    
composition & use to a regi/]$ product2 
regi/]$ s\rce ( active +r$i5t2 no data  
review on acute toxicity1 efficacy or   
,,crp - only product *emi/ry data2      
cite-all data citation1 or selective    
data citation :]e applicant owns all    
requir$ data1 or applicant submits      
specific au?orization lett] f data own]4
 ,category also includes #ajj re-package
 ( regi/]$ end-use or manufactur+-use   
product t requires no data submission   
nor data matrix4 7#b77c7da1ehb          
,r#cjadf,new product2 or simil>         
comb9ation product 7already regi/]$7 to 
an id5tical or sub/antially simil> 9    
composition & use to a regi/]$ product2 
regi/]$ s\rce ( active +r$i5t2 selective
 data citation only = data on product   
*emi/ry &_/or acute toxicity &_/or      
public heal? pe/ efficacy 7id5tical data
 citation & claims to cit$ product7s771 
:]e applicant does n own all requir$    
data & does n h a specific au?orization 

lett] f data own]4 7#b77c7da1hig        
,r#cajdg,new end-use or manufactur+-use 
product ) regi/]$ s\rce7s7 ( active     
+r$i5t7s72 includes products conta9+ two
 or m regi/]$ active +r$i5ts previ\sly  
comb9$ 9 o!r regi/]$ products2 excludes 
products requir+ or cit+ an animal      
safety /udy2 requires review ( data     
package )9 ,,rd only2 includes data     
&_/or waiv]s ( data = only3 product     
*emi/ry &_/or acute toxicity &_/or *ild 
resi/ant packag+ &_/or pe/7s7 requir+   
efficacy 7#d7 - = up to #c t>get pe/s4  
7#b77c7gg1cja ,r#caddh,new end use      
product conta9+ up to ?ree regi/]$      
active +r$i5ts nev] be=e regi/]$ z ?is  
comb9ation 9 a =mulat$ product2 new     
product label is id5tical or            
sub/antially simil> to ! labels (       
curr5tly regi/]$ products :i* sep>ately 
conta9 ! respective compon5t active     
+r$i5ts2 excludes products requir+ or   
cit+ an animal safety /udy2 requires    
review ( data package )9 ,,rd only2     
includes data &_/or waiv]s ( data =     

only3 product *emi/ry &_/or acute       
toxicity &_/or  *ild resi/ant packag+   
&_/or pe/7s7 requir+ efficacy 7#d7 - =  
up to #c t>get pe/s4 7#b77c7hh1fbf      
,r#caidi,new end use product conta9+ up 
to ?ree regi/]$ active +r$i5ts nev] be=e
 regi/]$ z ?is comb9ation 9 a =mulat$   
product2 new product label is id5tical  
or sub/antially simil> to ! labels (    
curr5tly regi/]$ products :i* sep>ately 
conta9 ! respective compon5t active     
+r$i5ts2 excludes products requir+ or   
cit+ an animal safety /udy2 requires    
review ( data package )9 ,,rd only2     
includes data &_/or waiv]s ( data =     
only3 product *emi/ry &_/or acute       
toxicity &_/or  *ild resi/ant packag+   
&_/or pe/7s7 requir+ efficacy 7#d7 - =  
#d to #g t>get pe/s4 7#b77c7ajab1fbf    
,r#cahej 7new7,new end use product      
conta9+ f\r or m regi/]$ active +r$i5ts 
nev] be=e regi/]$ z ?is comb9ation 9 a  
=mulat$ product2 new product label is   
id5tical or sub/antially simil> to !    
labels ( curr5tly regi/]$ products :i*  

sep>ately conta9 ! respective compon5t  
active +r$i5ts2 excludes products       
requir+ or cit+ an animal safety /udy2  
requires review ( data package )9 ,,rd  
only2 includes data &_/or waiv]s ( data 
= only3 product *emi/ry &_/or acute     
toxicity &_/or *ild resi/ant packag+    
&_/or pe/7s7 requir+ efficacy 7#d7 - =  
up to #c t>get pe/s4 7#b77c7iac1beb     
,r#cbaea 7new7,new end use product      
conta9+ f\r or m regi/]$ active +r$i5ts 
nev] be=e regi/]$ z ?is comb9ation 9 a  
=mulat$ product2 new product label is   
id5tical or sub/antially simil> to !    
labels ( curr5tly regi/]$ products :i*  
sep>ately conta9 ! respective compon5t  
active +r$i5ts2 excludes products       
requir+ or cit+ an animal safety /udy2  
requires review ( data package )9 ,,rd  
only2 includes data &_/or waiv]s ( data 
= only3 product *emi/ry &_/or acute     
toxicity &_/or *ild resi/ant packag+    
&_/or pe/7s7 requir+ efficacy 7#d7 - =  
#d to #g t>get pe/s4 7#b77c7aaag1beb    
,r#caeeb,new end-use1 on-animal product1

 regi/]$ s\rce ( active +r$i5t7s71 ) !  
submission ( data &_/or waiv]s = only3  
animal safety & pe/7s7 requir+ efficacy 
7#d7 &_/or product *emi/ry &_/or acute  
toxicity &_/or  *ild resi/ant packag+4  
7#b7 7#c7ii1hbj ,r#cafec 7new7,new      
end-use or manufactur+ product ) regi/]$
 s\rce7s7 ( active +r$i5t7s7 includ+    
products conta9+ two or m regi/]$ active
 +r$i5ts previ\sly comb9$ 9 o!r regi/]$ 
products2 excludes products requir+ or  
cit+ an animal safety /udy2 & requires  
review ( data &_/or waiv]s = only3      
product *emi/ry &_/or acute toxicity    
&_/or  *ild resi/ant packag+ &_/or      
pe/7s7 requir+ efficacy 7#d7 - = great] 
?an #c & up to #g t>get pe/s4           
7#b77c7iaa1cja ,r#caged 7new7,new       
end-use or manufactur+ product ) regi/]$
 s\rce7s7 ( active +r$i5t7s7 includ+    
products conta9+ #b or m regi/]$ active 
+r$i5ts previ\sly comb9$ 9 o!r regi/]$  
products2 excludes products requir+ or  
cit+ an animal safety /udy2 & requires  
review ( data &_/or waiv]s = only3      

product *emi/ry &_/or acute toxicity    
&_/or  *ild resi/ant packag+ &_/or      
pe/7s7 requir+ efficacy 7#d7 - = great] 
?an #g t>get pe/s4 7#b77c7ajae1cja      
,r#cbjee,new product2 new physical =m2  
requires data review 9 sci5ce divisions4
 7#b77c7abac1bbf ,r#ccaef,new product2  
repack ( id5tical regi/]$ end-use       
product z a manufactur+-use product1 or 
id5tical regi/]$ manufactur+-use product
 z an end use product2 same regi/]$ uses
 only4 7#b77c7cb1ecj ,r#ccbeg,new       
manufactur+-use product2 regi/]$ active 
+r$i5t2 unregi/]$ s\rce ( active +r$i5t2
 submission ( completely new g5]ic data 
package2 regi/]$ uses only2 requires    
review 9 ,,rd & sci5ce divisions4       
7#b77c7bdbhc1bae ,r#ccceh,new product2  
,,mup or ,end use product ) unregi/]$   
s\rce ( active +r$i5t2 requires sci5ce  
data review2 new physical =m2 etc4      
,cite-all or selective data citation :]e
 applicant owns all requir$ data4       
7#b77c7ajai1hch ,r#ccdei,new product2   
,,mup or ,end use product ) unregi/]$   

s\rce ( ! active +r$i5t2 requires sci5ce
 data review2 new physical =m2 etc4     
,selective data citation4               
7#b77c7aabc1ajj ,,table #e4 --          
,,regi/ration ,,division -- ,,am5dm5ts  
,,epa ,no4,new ,,cr ,no4,action,decision
 ,review ,"t 7,mon?s77#a7 ,regi/ration  
,s]vice ,fee 77 7#a7 ,a decision review 
"t t w\ld o!rwise end on a ,saturday1   
,sunday1 or f$]al holiday1 w be ext5d$  
to end on ! next bus9ess day4 7#b7 7a7  
,,epa-initiat$ am5dm5ts %all n be *>g$  
regi/ration s]vice fees4 7b7            
,regi/rant-initiat$ fa/-track am5dm5ts  
are to be complet$ )9 ! timel9es        
specifi$ 9 ,,fifra ,section             
#c7;c77#c77;,b7 & are n subject to      
regi/ration s]vice fees4 7c7            
,regi/rant-initiat$ fa/-track am5dm5ts  
h&l$ by ! ,antimicrobials ,division are 
to be complet$ )9 ! timel9es specifi$ 9 
,,fifra ,section #c7;h7 & are n subject 
to regi/ration s]vice fees4 7d7         
,regi/rant initiat$ am5dm5ts submitt$ by
 notification "u ,,pr ,notices1 su* z   

,,pr ,notice #ih-aj1 cont9ue "u ,,pr    
,notice timel9es & are n subject to     
regi/ration s]vice fees4 7e7            
,submissions ) data & requir+ data      
review are subject to regi/ration s]vice
 fees4 7#c7 ,:]e ! action involves      
approval ( a new or am5d$ label1 on or  
be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 
made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     
support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        

describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 7#d7 ,= ! purposes (       
classify+ propos$ regi/ration actions   
into ,,pria categories1 8pe/7s7 requir+ 
efficacy0 are3 public heal? pe/s li/$ 9 
,,pr ,notice #bjjb-a1 live/ock pe/s     
7e4g4 ,horn flies1 ,/able flies71       
wood-de/roy+ pe/s 7e4g4 t]mites1 c>p5t] 
ants1 wood-bor+ beetles7 & c]ta9        
invasive species 7e4g4 ,asian ,longhorn$
 beetle1 ,em]ald ,a%bor]74 ,?is li/ may 
be updat$_/ref9$ z invasive pe/ ne$s    
arise4 ,to det]m9e ! numb] ( pe/s = !   
,,pria categories1 pe/s h be5 plac$ into
 gr\ps 7g5]al2 e4g41 cockroa*es7 & pe/  
specific 7specifically a te/ species74  

,if seek+ a label claim aga9/ a pe/ gr\p
 7g5]al71 use ! gr\p li/+ bel[ & ea*    
gr\p w c\nt z #a4 ,! g5]al pe/s gr\ps   
are3 mites1 du/ mites1 *igg]s1 ticks1   
h>d ticks1 s(t ticks1 cattle ticks1     
scorpions1 spid]s1 c5tip$es1 lice1      
fleas1 cockroa*es1 k$s1 bot flies1      
screwworms1 fil? flies1 bl[ flies1 h\se 
flies1 fle% flies1 mosquitoes1 bit+     
flies1 horse flies1 /able flies1 de]    
flies1 s& flies1 bit+ midges1 black     
flies1 true bugs1 b$ bugs1 /++ bees1    
wasps1 yell[ jackets1 hornets1 ants     
7exclud+ c>p5t] ants71 fire & h>ve/]    
ants1 wood de/roy+ beetles1 c>p5t] ants1
 t]mites1 subt]ranean t]mites1 dry wood 
t]mites1 arboreal t]mites1 damp wood    
t]mites & invasive species4 ,if seek+ a 
claim aga9/ a specific pe/ )\t a g5]al  
claim !n ea* specific pe/ w c\nt z #a4  
,r#cdjfj;,am5dm5t requir+ data review )9
 ,,rd 7e4g41 *anges to precaution>y     
label /atem5ts72 includes add+_/modify+ 
pe/7s7 claims = up to #b t>get pe/s1    
excludes products requir+ or cit+ an    

animal safety /udy4 7#b77c77d7dd1ihh    
,r#cdafa 7,new7,am5dm5t requir+ data    
review )9 ,,rd 7e4g41 *anges to         
precaution>y label /atem5ts71 includes  
add+_/modify+ pe/7s7 claims = great] ?an
 #b t>get pe/s1 excludes products       
requir+ or cit+ an animal safety /udy4  
7#b77c77d7fe1ihh ,r#cdefb;,am5d+        
on-animal products previ\sly regi/]$1 ) 
! submission ( data &_/or waiv]s = only3
  animal safety & pe/7s7 requir+        
efficacy 7#d7 &_/or product *emi/ry     
&_/or acute toxicity &_/or  *ild        
resi/ant packag+4 7#b77c7gh1hbj         
,r#cejfc;,am5dm5t requir+ data review 9 
sci5ce divisions 7e4g41 *anges to ,,rei1
 or ,,ppe1 or ,,phi1 or use rate1 or    
numb] ( applications2 or add a]ial      
application2 or modify ,,gw_/,,sw       
advisory /atem5t74 7#b77c7iac1bbf       
,r#ceafd;,am5dm5t add+ a new unregi/]$  
s\rce ( active +r$i5t4 7#b77c7hac1bbf   
,r#cebfe;,am5dm5t add+ already approv$  
uses2 selective me?od ( support2 does n 
apply if ! applicant owns all cit$ data4

 7#b7 7#c7hac1bbf ,r#cgaff;,am5dm5t to  
,exp]im5tal ,use ,p]mit2 7does n include
 ext5d+ a p]mit's "t p]iod74 7#c7faj1jij
 ,,table #f4 -- ,,regi/ration ,,division
 -- ,,o!r ,,actions ,,epa ,no4,new ,,cr 
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
77 7#a7 ,a decision review "t t w\ld    
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day4 ,r#abdfg;,conditional 
,rul+ on ,pre-application ,/udy ,waiv]s2
 applicant-initiat$4#fb1ecj             
,r#bgbfh,review ( ,/udy ,protocol       
applicant-initiat$2 excludes ,,d>t1     
pre-regi/ration conf]5ce1 ,rapid        
,response review1 ,,dnt protocol review1
 protocol ne$+ ,,hsrb review4#cb1ecj    
,r#bgefi,rebuttal ( ag5cy review$       
protocol1 applicant initiat$4#cb1ecj    
,r#cgjgj;,canc] reassessm5t2            
applicant-initiat$4#ahaih1bej ,,table   
#g4 -- ,,antimicrobials ,,division --   
,,new ,,active ,,+r$i5ts ,,epa ,no4,new 
,,cr ,no4,action,decision ,review ,"t   

7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
77 7#a7 ,a decision review "t t w\ld    
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day4 7#b7 ,all reque/s =   
new uses 7food &_/or nonfood7 conta9$ 9 
any application = a new active +r$i5t or
 a fir/ food use are cov]$ by ! base fee
 = t new active +r$i5t or fir/ food use 
application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   
fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 

"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application4 7#c7 ,:]e ! action involves
 approval ( a new or am5d$ label1 on or 

be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 
made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     
support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  

,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 ,a#chjga,new ,active       
,+r$i5t2 ,indirect ,food use2 e/abli%   
tol]ance or tol]ance exemption if       
requir$4 7#b77c7bdacg1hda ,a#cijgb,new  
,active ,+r$i5t2 ,direct ,food use2     
e/abli% tol]ance or tol]ance exemption  
if requir$4 7#b77c7bdbbi1gcc            
,a#dajgc,new ,active ,+r$i5t ,non-food  
use47#b77c7babbi1gcc ,a#dcagd,new       
,active ,+r$i5t1 ,non-food use2 l[-risk4
 7#b77c7abhj1bbe ,,table #h4 --         
,,antimicrobials ,,division -- ,,new    
,,uses ,,epa ,no4,new ,,cr              
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
77 7#a7 ,a decision review "t t w\ld    
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day4 7#b7 ,all reque/s =   
new uses 7food &_/or nonfood7 conta9$ 9 
any application = a new active +r$i5t or
 a fir/ food use are cov]$ by ! base fee

 = t new active +r$i5t or fir/ food use 
application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   
fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 

active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application4 7#c7 ,if ,,epa data rules  
are am5d$ to newly require cle>ance "u  
section #djh ( ! ,,ffdca = an +r$i5t (  
an antimicrobial product :]e su* +r$i5t 
0 n previ\sly subject to su* a cle>ance1
 !n review ( ! data = su* cle>ance ( su*
 product is n subject to a regi/ration  
s]vice fee = ! tol]ance action = two    
ye>s f ! effective date ( ! rule4 7#d7  
,:]e ! action involves approval ( a new 

or am5d$ label1 on or be=e ! end date ( 
! decision review "t1 ! ,ag5cy %all     
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  

,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 7#e7 ,am5dm5t applications 
to add ! new use7s7 to regi/]$ product  
labels are cov]$ by ! base fee = ! new  
use7s74 ,all items 9 ! cov]$ application
 mu/ be submitt$ toge!r 9 "o package4   
,ea* application = an additional new    
product regi/ration & new in]t          
approval7s7 t is submitt$ 9 ! new use   
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,h[ev]1 if a new
 use application only proposes to regi/]
 ! new use = a new product & !re are no 
am5dm5ts 9 ! application1 !n review ( "o
 new product application is cov]$ by !  
new use fee4 ,all su* associat$         
applications t are submitt$ toge!r w be 
subject to ! new use decision review "t4
 ,any application = a new product or an 
am5dm5t to ! propos$ label+ 7a7 submitt$
 subsequ5t to submission ( ! new use    
application & 7b7 prior to conclusion ( 

its decision review "t & 7c7 conta9+ !  
same new uses1 w be deem$ a sep>ate     
new-use application1 subject to a       
sep>ate regi/ration s]vice fee & new    
decision review "t = a new use4 ,if !   
new-use application includes non-food   
7indoor &_/or outdoor71 & food 7outdoor 
&_/or indoor7 uses1 ! appropriate fee is
 due = ea* type ( new use & ! longe/    
decision review "t applies to all ( !   
new uses reque/$ 9 ! application4 ,any  
in=mation t 7a7 0 nei!r reque/$ nor     
requir$ by ! ,ag5cy1 & 7b7 is submitt$  
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre51 & 7c7 is n itself a cov]$        
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new use application4 ,a#ddjge,new ,use1 
,indirect ,food ,use1 e/abli% tol]ance  
or tol]ance exemption4                  
7#b77c77d7baca1iaj ,a#ddagf;,additional 
,indirect food uses2 e/abli% tol]ances  
or tol]ance exemptions if requir$2 #f or

 m submitt$ 9 "o application4           
7#c77d77e7baaad1hgj ,a#dejgg,new use1   
,direct food use1 e/abli% tol]ance or   
tol]ance exemption4 7#b77c77d7baie1gbd  
,a#deagh;,additional ,direct food uses2 
e/abli% tol]ances or tol]ance exemptions
 if requir$2 #f or m submitt$ 9 "o      
application4 7#c77d77e7baahb1cce        
,a#ejjgi,new use1 non-food4             
7#d77e7abca1iaj ,a#ejahj,new use1       
non-food2 #f or m submitt$ 9 "o         
application4 7#d77e7aegf1ehc ,,table #i4
 -- ,,antimicrobials ,,division -- ,,new
 ,,products ,,& ,,am5dm5ts ,,epa        
,no4,new ,,cr ,no4,action,decision      
,review ,"t 7,mon?s77#a7 ,regi/ration   
,s]vice ,fee 77 7#a7 ,a decision review 
"t t w\ld o!rwise end on a ,saturday1   
,sunday1 or f$]al holiday1 w be ext5d$  
to end on ! next bus9ess day4 7#b7 ,an  
application = a new end-use product us+ 
a s\rce ( active +r$i5t t 7a7 is n yet  
regi/]$ b 7b7 has an application p5d+ ) 
! ,ag5cy = review1 w be consid]$ an     
application = a new product ) an        

unregi/]$ s\rce ( active +r$i5t4 7#c7   
,:]e ! action involves approval ( a new 
or am5d$ label1 on or be=e ! end date ( 
! decision review "t1 ! ,ag5cy %all     
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       

includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 7#d77;a7 ,,epa-initiat$    
am5dm5ts %all n be *>g$ regi/ration     
s]vice fees4 7b7 ,regi/rant-initiat$    
fa/-track am5dm5ts are to be complet$ )9
 ! timel9es specifi$ 9 ,,fifra ,section 
#c7;c77#c77;,b7 & are n subject to      
regi/ration s]vice fees4 7c7            
,regi/rant-initiat$ fa/-track am5dm5ts  
h&l$ by ! ,antimicrobials ,division are 
to be complet$ )9 ! timel9es specifi$ 9 
,,fifra ,section #c7;h7 & are n subject 
to regi/ration s]vice fees4 7d7         
,regi/rant initiat$ am5dm5ts submitt$ by
 notification "u ,,pr ,notices1 su* z   
,,pr ,notice #ih-aj1 cont9ue "u ,,pr    
,notice timel9es & are n subject to     
regi/ration s]vice fees4 7e7            
,submissions ) data & requir+ data      
review are subject to regi/ration s]vice
 fees4 7#e7 ,! applicant mu/ id5tify !  

sub/antially simil> product if opt+ to  
use cite-all or ! selective me?od to    
support acute toxicity data requirem5ts4
 7#f7 ,once a submission = a new product
 ) public heal? organisms has be5       
submitt$ & classifi$ 9 ei!r ,a#edj or   
,a#eda1 additional organisms submitt$ = 
! same product be=e expiration ( ! fir/ 
submission's orig9al decision review "t 
p]iod w result 9 reclassification ( bo? 
! orig9al & subsequ5t submission into ! 
appropriate new category bas$ on ! sum (
 ! numb] ( organisms 9 bo? submissions4 
,a reclassification w\ld result 9 a new 
,,pria />t date & require additional    
fees to meet ! fee ( ! new category4    
7#g7 ,once a submission = a label       
am5dm5t ) public heal? organisms has be5
 submitt$ & classifi$ 9 ei!r ,a#egj or  
,a#egc1 additional organisms submitt$ = 
! same product be=e expiration ( ! fir/ 
submission's orig9al decision review "t 
p]iod w result 9 reclassification ( bo? 
! orig9al & subsequ5t submission into ! 
appropriate new category bas$ on ! sum (

 ! numb] ( organisms 9 bo? submissions4 
,a reclassification w\ld result 9 a new 
,,pria />t date & require additional    
fees to meet ! fee ( ! new category4    
,a#ecjha ,new product1 id5tical or      
sub/antially simil> 9 composition & use 
to a regi/]$ product2 no data review or 
only product *emi/ry data2 cite all data
 citation or selective data citation :]e
 applicant owns all requir$ data2 or    
applicant submits specific au?orization 
lett] f data own]4 ,category also       
includes #ajj re-package ( regi/]$      
end-use or manufactur+ use product t    
requires no data submission nor data    
matrix4 7#b77c7 #d #a1bgh ,a#ecahb ,new 
product2 id5tical or sub/antially simil>
 9 composition & use to a regi/]$       
product2 regi/]$ s\rce ( active +r$i5t3 
selective data citation only = data on  
product *emi/ry &_/or acute toxicity    
&_/or public heal? pe/ efficacy1 :]e    
applicant does n own all requir$ data & 
does n h a specific au?orization lett] f
 data own]4 7#b77c7da1hbd ,a#ecbhc,new  

product2 id5tical or sub/antially simil>
 9 composition & use to a regi/]$       
product2 regi/]$ active +r$i5t2         
unregi/]$ s\rce ( active +r$i5t2        
cite-all data citation except = product 
*emi/ry2 product *emi/ry data submitt$4 
7#b77c7 #ee1ajg ,a#edjhd ,new end use   
product2 ,,fifra #b7mm7 uses only2 up to
 #be public heal? organisms4            
7#b77c77e77f7e #e1ajg ,a#edahe 7new7    
,new end use product2 ,,fifra #b7mm7    
uses only2 #bf-ej public heal?          
organisms4 7#b77c77e77f7gh1ejj ,a#edbhf 
7new7 ,new end use product2 ,,fifra     
#b7mm7 uses only2  #ea public heal?     
organisms4 7#b77c77e7ajae1jjj ,a#eejhg  
,new end-use product2 uses o!r ?an      
,,fifra #b7mm72 non-,,fqpa product4     
7#b77c77e7iac1bbf ,a#efjhh ,new         
manufactur+ use product2 regi/]$ active 
+r$i5t2 selective data citation4        
7#b77c7fab1eif ,a#efehi 7new7 ,new      
manufactur+-use product2 regi/]$ active 
+r$i5t2 unregi/]$ s\rce ( active +r$i5t2
 submission ( new g5]ic data package2   

regi/]$ uses only2 requires sci5ce      
review4 7#b77c7 #abah1bcd ,a#egjij      
,label am5dm5t requir+ data review2 up  
to #be public heal? organisms4          
7#c77d77e77f7dc1hca ,a#egcia 7new7      
,label am5dm5t requir+ data review2     
#bf-ej public heal? organisms4          
7#b77c77e77g7ff1cej ,a#egdib 7new7      
,label am5dm5t requir+ data review2  #ea
 public heal? organisms4                
7#b77c77e77g7iaa1jjj ,a#egbic,new       
,product or am5dm5t requir+ data review 
= risk assessm5t by ,sci5ce ,bran*      
7e4g41 *anges to ,,rei1 or ,,ppe1 or use
 rate74 7#b77c77d7iac1bbf ,,table #aj4  
-- ,,antimicrobials ,,division --       
,,exp]im5tal ,,use ,,p]mits ,,& ,,o!r   
,,actions ,,epa ,no4,new ,,cr           
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
77 7#a7 ,a decision review "t t w\ld    
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day4 7#b7 ,:]e ! action    
involves approval ( a new or am5d$      

label1 on or be=e ! end date ( !        
decision review "t1 ! ,ag5cy %all       
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  

,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 ,a#ebjid ,exp]im5tal ,use  
,p]mit application1 non-food use4 7#b7  
#i #f1chc ,a#ebaie,review ( public heal?
 efficacy /udy protocol )9 ,,ad1 p] ,,ad
 ,int]nal ,guidance = ! ,efficacy       
,protocol ,review ,process2 ,code w also
 include review ( public heal? efficacy 
/udy protocol & data review = devices   
mak+ pe/icidal claims2                  
applicant-initiat$2 ,ti] #a4dd1gbf      
,a#ebbif ,review ( public heal? efficacy
 /udy protocol outside ,,ad by memb]s ( 
,,ad ,efficacy ,protocol ,review ,exp]t 
,panel2 ,code w also include review (   
public heal? efficacy /udy protocol &   
data review = devices mak+ pe/icidal    
claims2 applicant-initiat$2 ,ti]        
#b4abab1aef ,a#ecgig 7new7 ,new ,active 
,+r$i5t_/,new ,use1 ,exp]im5tal ,use    
,p]mit application2 ,direct food use2   
,e/abli% tol]ance or tol]ance exemption 
if requir$4 ,cr$it #de ( fee t[>d new   

active +r$i5t_/new use application t    
foll[s4#ah #aec1aef ,a#echih 7new7 ,new 
,active ,+r$i5t_/,new ,use1 ,exp]im5tal 
,use ,p]mit application2 ,indirect food 
use2 ,e/abli% tol]ance or tol]ance      
exemption if requir$ ,cr$it #de ( fee   
t[>d new active +r$i5t_/new use         
application t foll[s4#ahie1gbd ,a#eciii 
7new7 ,new ,active ,+r$i5t_/,new ,use1  
,exp]im5tal ,use ,p]mit application2    
,nonfood use4 ,cr$it #de ( fee t[>d new 
active +r$i5t_/new use application t    
foll[s4#aeib1afc ,a#ebiajj ,am5dm5t to  
,exp]im5tal ,use ,p]mit2 requires data  
review or risk assessm5t4 7#b7 #iaa1dbi 
,a#ebcaja ,review ( protocol o!r ?an a  
public heal? efficacy /udy 7i4e41       
,toxicology or ,exposure                
,protocols74#iab1aef ,a#egaajb ,sci5ce  
reassessm5t3 ,canc] risk1 ref9$         
ecological risk1 &_/or endang]$ species2
 applicant-initiat$4 #ahie1gbd ,a#eccajc
 7new7,exemption f ! requirem5t ( an    
,exp]im5tal ,use ,p]mit4 7#b7 #db1dhb   
,a#ecdajd 7new7 ,rebuttal ( ag5cy       

review$ protocol1 applicant initiat$4   
#dd1gbf ,a#eceaje 7new7 ,conditional    
,rul+ on ,pre-application ,/udy ,waiv]  
or ,data ,bridg+ ,argum5t2              
applicant-initiat$4 #fb1dji ,a#ecfajf   
7new7,conditional ,rul+ on              
,pre-application ,direct ,food1         
,indirect ,food1 ,nonfood use           
det]m9ation2 applicant-initiat$4#db1dhb 
,,table #aa4 -- ,,biope/icides          
,,division -- ,,new ,,active ,,+r$i5ts  
,,epa ,no4,new ,,cr ,no4,action,decision
 ,review ,"t 7,mon?s77#a7 ,regi/ration  
,s]vice ,fee 77 7#a7 ,a decision review 
"t t w\ld o!rwise end on a ,saturday1   
,sunday1 or f$]al holiday1 w be ext5d$  
to end on ! next bus9ess day4 7#b7 ,all 
reque/s = new uses 7food &_/or nonfood7 
conta9$ 9 any application = a new active
 +r$i5t or a fir/ food use are cov]$ by 
! base fee = t new active +r$i5t or fir/
 food use application & reta9 ! same    
decision "t review p]iod z ! new active 
+r$i5t or fir/ food use application4 ,! 
application mu/ be receiv$ by ! ag5cy 9 

"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   

decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application4 7#c7 ,:]e ! action involves
 approval ( a new or am5d$ label1 on or 
be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 
made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     
support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  

by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 ,b#ehjajg,new active       
+r$i5t2 food use2 petition to e/abli% a 
tol]ance4 7#b77c7 #bj #ea1jec ,b#eijajh 
,new active +r$i5t2 food use2 petition  
to e/abli% a tol]ance exemption4        
7#b77c7ahca1iaj ,b#fjjaji ,new active   
+r$i5t2 non-food use4 7#b77c7 #acai1adf 
,b#fajaaj ,new active +r$i5t2           
,exp]im5tal ,use ,p]mit application2    
petition to e/abli% a tempor>y tol]ance 

or tempor>y tol]ance exemption4 7#c7 #aj
 #ab1gfd ,b#faaaaa ,new active +r$i5t2  
,exp]im5tal ,use ,p]mit application2    
petition to e/abli% p]man5t tol]ance    
exemption4 7#c7abab1gfd ,b#fabaab ,new  
active +r$i5t2 no *ange to a p]man5t    
tol]ance exemption4 7#b77c7ajag1eej     
,b#facaac ,new active +r$i5t2 petition  
to conv]t a tempor>y tol]ance or a      
tempor>y tol]ance exemption to a p]man5t
 tol]ance or tol]ance exemption4        
7#b77c7aaag1eej ,b#fbjaad ,new active   
+r$i5t2 ,exp]im5tal ,use ,p]mit         
application2 non-food use includ+ crop  
de/ruct4 7#c7gf1chc ,,table #ab4 --     
,,biope/icides ,,division -- ,,new      
,,uses ,,epa ,no4,new ,,cr              
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
77 7#a7 ,a decision review "t t w\ld    
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day4 7#b7 ,all reque/s =   
new uses 7food &_/or nonfood7 conta9$ 9 
any application = a new active +r$i5t or

 a fir/ food use are cov]$ by ! base fee
 = t new active +r$i5t or fir/ food use 
application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   
fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   

s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application4 7#c7 ,am5dm5t applications 
to add ! new use7s7 to regi/]$ product  
labels are cov]$ by ! base fee = ! new  
use7s74 ,all items 9 ! cov]$ application
 mu/ be submitt$ toge!r 9 "o package4   
,ea* application = an additional new    
product regi/ration & new in]t          
approval7s7 t is submitt$ 9 ! new use   
application package is subject to !     

regi/ration s]vice fee = a new product  
or a new in]t approval4 ,h[ev]1 if a new
 use application only proposes to regi/]
 ! new use = a new product & !re are no 
am5dm5ts 9 ! application1 !n review ( "o
 new product application is cov]$ by !  
new use fee4 ,all su* associat$         
applications t are submitt$ toge!r w be 
subject to ! new use decision review "t4
 ,any application = a new product or an 
am5dm5t to ! propos$ label+ 7a7 submitt$
 subsequ5t to submission ( ! new use    
application & 7b7 prior to conclusion ( 
its decision review "t & 7c7 conta9+ !  
same new uses1 w be deem$ a sep>ate     
new-use application1 subject to a       
sep>ate regi/ration s]vice fee & new    
decision review "t = a new use4 ,if !   
new-use application includes non-food   
7indoor &_/or outdoor71 & food 7outdoor 
&_/or indoor7 uses1 ! appropriate fee is
 due = ea* type ( new use & ! longe/    
decision review "t applies to all ( !   
new uses reque/$ 9 ! application4 ,any  
in=mation t 7a7 0 nei!r reque/$ nor     

requir$ by ! ,ag5cy1 & 7b7 is submitt$  
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre51 & 7c7 is n itself a cov]$        
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new use application4 7#d7 ,:]e ! action 
involves approval ( a new or am5d$      
label1 on or be=e ! end date ( !        
decision review "t1 ! ,ag5cy %all       
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   

resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 ,b#fcjaae ,fir/ food use2  
petition to e/abli% a tol]ance          
exemption4 7#b77d7 #ac #ab1gfd ,b#fcaaaf
 ,new food use2 petition to am5d an     
e/abli%$ tol]ance4 7#c77d7abab1gfd      
,b#fdjaag;,fir/ food use2 petition to   
e/abli% a tol]ance4 7#b77d7 #aiai1adf   
,b#fdcaah,new ,food use2 petition to    
am5d an e/abli%$ tol]ance exemption4    
7#c77d7 #aj #ab1gfd ,b#fdbaai;,fir/ food
 use2 indoor2 food_/food h&l+4          
7#b77d7abca1iaj ,b#fddabj,new use1 no   
*ange to an e/abli%$ tol]ance or        

tol]ance exemption4 7#c77d7hab1gfd      
,b#fejaba,new use2 non-food4            
7#c77d7gf1chc ,b#fdeabb 7new7 ,new food 
use2 ,exp]im5tal ,use ,p]mit            
application2 petition to am5d or add a  
tol]ance exemption4 7#d7abab1gfd        
,b#fdfabc 7new7,new use2 non-food use   
includ+ crop de/ruct2 ,exp]im5tal ,use  
,p]mit application4 7#d7 #gf1chc ,,table
 #ac4 -- ,,biope/icides ,,division --   
,,new ,,products ,,epa ,no4,new ,,cr    
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
77 7#a7 ,a decision review "t t w\ld    
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day4 7#b7 ,an application =
 a new end-use product us+ a s\rce (    
active +r$i5t t 7a7 is n yet regi/]$ b  
7b7 has an application p5d+ ) ! ,ag5cy =
 review1 w be consid]$ an application = 
a new product ) an unregi/]$ s\rce (    
active +r$i5t4 7#c7 ,:]e ! action       
involves approval ( a new or am5d$      
label1 on or be=e ! end date ( !        

decision review "t1 ! ,ag5cy %all       
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 

bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 ,b#febabd,new product2     
regi/]$ s\rce ( active +r$i5t2 requires 
petition to am5d e/abli%$ tol]ance or   
tol]ance exemption2 requires #a7        
submission ( product specific data2 or  
#b7 citation ( previ\sly review$ &      
accept$ data2 or #c7 submission or      
citation ( data g5]at$ at gov]nm5t      
exp5se2 or #d7 submission or citation ( 
sci5tifically-s\nd rationale bas$ on    
publicly available lit]ature or o!r     
relevant in=mation t addresses ! data   
requirem5t2 or #e7 submission ( a reque/
 = a data requirem5t to be waiv$        
support$ by a sci5tifically-s\nd        
rationale expla9+ :y ! data requirem5t  
does n apply4 7#b77c7 #ac #ab1gfd       
,b#ffjabe ,new product2 regi/]$ s\rce ( 
active +r$i5t7s72 id5tical or           
sub/antially simil> 9 composition & use 
to a regi/]$ product4 ,no data review1  
or only product *emi/ry data2 cite-all  
data citation1 or selective data        

citation :]e applicant owns all requir$ 
data or au?orization f data own] is     
demon/rat$4 ,category includes #ajj     
re-package ( regi/]$ end-use or         
manufactur+-use product t requires no   
data submission or data matrix4 ,=      
microbial pe/icides1 ! active +r$i5t7s7 
mu/ n be re-isolat$4 7#b77c7da1bgh      
,b#fgjabf ,new product2 regi/]$ s\rce ( 
active +r$i5t7s72 requires3 #a7         
submission ( product specific data2 or  
#b7 citation ( previ\sly review$ &      
accept$ data2 or #c7 submission or      
citation ( data g5]at$ at gov]nm5t      
exp5se2 or #d7 submission or citation ( 
a sci5tifically-s\nd rationale bas$ on  
publicly available lit]ature or o!r     
relevant in=mation t addresses ! data   
requirem5t2 or #e7 submission ( a reque/
 = a data requirem5t to be waiv$        
support$ by a sci5tifically-s\nd        
rationale expla9+ :y ! data requirem5t  
does n apply4 7#b77c7 #ge1ajg ,b#fgaabg 
,new product2 unregi/]$ s\rce ( active  
+r$i5t7s72 requires a petition to am5d  

an e/abli%$ tol]ance or tol]ance        
exemption2 requires3 #a7 submission (   
product specific data2 or #b7 citation (
 previ\sly review$ & accept$ data2 or   
#c7 submission or citation ( data g5]at$
 at gov]nm5t exp5se2 or #d7 submission  
or citation ( a sci5tifically-s\nd      
rationale bas$ on publicly available    
lit]ature or o!r relevant in=mation t   
addresses ! data requirem5t2 or #e7     
submission ( a reque/ = a data          
requirem5t to be waiv$ support$ by a    
sci5tifically-s\nd rationale expla9+ :y 
! data requirem5t does n apply4 7#b77c7 
#ag #ab1gfd ,b#fgbabh ,new product2     
unregi/]$ s\rce ( active +r$i5t7s72     
non-food use or food use requires3 #a7  
submission ( product specific data2 or  
#b7 citation ( previ\sly review$ &      
accept$ data2 or #c7 submission or      
citation ( data g5]at$ at gov]nm5t      
exp5se2 or #d7 submission or citation ( 
a sci5tifically-s\nd rationale bas$ on  
publicly available lit]ature or o!r     
relevant in=mation t addresses ! data   

requirem5t2 or #e7 submission ( a reque/
 = a data requirem5t to be waiv$        
support$ by a sci5tifically-s\nd        
rationale expla9+ :y ! data requirem5t  
does n apply4 7#b77c7aci1aah ,b#fgcabi  
,new product ,,mup_/,,ep2 unregi/]$     
s\rce ( active +r$i5t7s72 citation (    
,te*nical ,grade ,active ,+r$i5t        
7,,tgai7 data previ\sly review$ &       
accept$ by ! ,ag5cy4 ,requires an ,ag5cy
 det]m9ation t ! cit$ data supports !   
new product4 7#b77c7aje1ajg ,b#fgdacj   
,new product ,,mup2 ,repack ( id5tical  
regi/]$ end-use product z a             
manufactur+-use product2 same regi/]$   
uses only4 7#b77c7da1bgh ,b#fgeaca ,new 
,product ,,mup2 regi/]$ s\rce ( active  
+r$i5t2 submission ( completely new     
g5]ic data package2 regi/]$ uses only4  
7#b77c7aji1aah ,b#fgfacb ,new product2 m
 ?an "o active +r$i5t :]e "o active     
+r$i5t is an unregi/]$ s\rce2 product   
*emi/ry data mu/ be submitt$2 requires3 
#a7 submission ( product specific data1 
& #b7 citation ( previ\sly review$ &    

accept$ data2 or #c7 submission or      
citation ( data g5]at$ at gov]nm5t      
exp5se2 or #d7 submission or citation ( 
a sci5tifically-s\nd rationale bas$ on  
publicly available lit]ature or o!r     
relevant in=mation t addresses ! data   
requirem5t2 or #e7 submission ( a reque/
 = a data requirem5t to be waiv$        
support$ by a sci5tifically-s\nd        
rationale expla9+ :y ! data requirem5t  
does n apply4 7#b77c7 #aci1aah          
,b#fggacc,new end-use non-food animal   
product ) submission ( two or m t>get   
animal safety /udies2 includes data     
&_/or waiv]s ( data = only3 product     
*emi/ry &_/or acute toxicity &_/or      
public heal? pe/ efficacy &_/or animal  
safety /udies &_/or  *ild resi/ant      
packag+4 7#b77c7ajh1hbj ,,table #ad4 -- 
,,biope/icides ,,division -- ,,am5dm5ts 
,,epa ,no4,new ,,cr ,no4,action,decision
 ,review ,"t 7,mon?s77#a7 ,regi/ration  
,s]vice ,fee 77 7#a7 ,a decision review 
"t t w\ld o!rwise end on a ,saturday1   
,sunday1 or f$]al holiday1 w be ext5d$  

to end on ! next bus9ess day4 7#b7 7a7  
,,epa-initiat$ am5dm5ts %all n be *>g$  
regi/ration s]vice fees4 7b7            
,regi/rant-initiat$ fa/-track am5dm5ts  
are to be complet$ )9 ! timel9es        
specifi$ 9 ,,fifra ,section             
#c7;c77#c77;,b7 & are n subject to      
regi/ration s]vice fees4 7c7            
,regi/rant-initiat$ fa/-track am5dm5ts  
h&l$ by ! ,antimicrobials ,division are 
to be complet$ )9 ! timel9es specifi$ 9 
,,fifra ,section #c7;h7 & are n subject 
to regi/ration s]vice fees4 7d7         
,regi/rant initiat$ am5dm5ts submitt$ by
 notification "u ,,pr ,notices1 su* z   
,,pr ,notice #ih-aj1 cont9ue "u ,,pr    
,notice timel9es & are n subject to     
regi/ration s]vice fees4 7e7            
,submissions ) data & requir+ data      
review are subject to regi/ration s]vice
 fees4 7#c7 ,:]e ! action involves      
approval ( a new or am5d$ label1 on or  
be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 

made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     
support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  

to ! ,ag5cy4 ,b#fbaacd;,am5dm5t2        
,exp]im5tal ,use ,p]mit2 no *ange to an 
e/abli%$ tempor>y tol]ance or tol]ance  
exemption4 7#c7g #e1ajg                 
,b#fbbace;,am5dm5t2 ,exp]im5tal ,use    
,p]mit2 petition to am5d an e/abli%$ or 
tempor>y tol]ance or tol]ance exemption4
 7#c7aaab1gfd ,b#fdaacf;,am5dm5t ( an   
e/abli%$ tol]ance or tol]ance           
exemption4#acab1gfd ,b#fhjacg ,am5dm5t2 
regi/]$ s\rces ( active +r$i5t7s72 no   
new use7s72 no *anges to an e/abli%$    
tol]ance or tol]ance exemption4         
,requires data submission4 7#b77c7 #e   
#e1ajg ,b#fhaach ,am5dm5t2 unregi/]$    
s\rce ( active +r$i5t7s74 ,requires data
 submission4 7#b77c7gf1jgi ,b#fhcaci    
,label am5dm5t2 requires review_/update 
( previ\s risk assessm5t7s7 )\t data    
submission 7e4g41 label+ *anges to      
,,rei1 ,,ppe1 ,,phi74 7#b77c7fe1ajg     
,b#fhdadj ,am5d+ non-food animal product
 t includes submission ( t>get animal   
safety data2 previ\sly regi/]$4         
7#b77c7hh1hbj ,b#fheada 7new7 ,am5dm5t2 

add a new bio*emical unregi/]$ s\rce (  
active +r$i5t or a new microbial        
production site4 ,requires submission ( 
analysis ( samples data &               
s\rce_/production site-specific         
manufactur+ process description4        
7#c7ee1ajg ,,table #ae4 --              
,,biope/icides ,,division -- ,,sclp     
,,epa ,no4,new ,,cr ,no4,action,decision
 ,review ,"t 7,mon?s77#a7 ,regi/ration  
,s]vice ,fee 77 7#a7 ,a decision review 
"t t w\ld o!rwise end on a ,saturday1   
,sunday1 or f$]al holiday1 w be ext5d$  
to end on ! next bus9ess day4 7#b7 ,all 
reque/s = new uses 7food &_/or nonfood7 
conta9$ 9 any application = a new active
 +r$i5t or a fir/ food use are cov]$ by 
! base fee = t new active +r$i5t or fir/
 food use application & reta9 ! same    
decision "t review p]iod z ! new active 
+r$i5t or fir/ food use application4 ,! 
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    

product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 

by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application4 7#c7 ,an application = a   
new end-use product us+ a s\rce ( active
 +r$i5t t 7a7 is n yet regi/]$ b 7b7 has
 an application p5d+ ) ! ,ag5cy =       
review1 w be consid]$ an application = a
 new product ) an unregi/]$ s\rce (     
active +r$i5t4 7#d7 7a7 ,,epa-initiat$  
am5dm5ts %all n be *>g$ regi/ration     
s]vice fees4 7b7 ,regi/rant-initiat$    
fa/-track am5dm5ts are to be complet$ )9
 ! timel9es specifi$ 9 ,,fifra ,section 
#c7;c77#c77;,b7 & are n subject to      
regi/ration s]vice fees4 7c7            
,regi/rant-initiat$ fa/-track am5dm5ts  
h&l$ by ! ,antimicrobials ,division are 
to be complet$ )9 ! timel9es specifi$ 9 
,,fifra ,section #c7;h7 & are n subject 
to regi/ration s]vice fees4 7d7         

,regi/rant initiat$ am5dm5ts submitt$ by
 notification "u ,,pr ,notices1 su* z   
,,pr ,notice #ih-aj1 cont9ue "u ,,pr    
,notice timel9es & are n subject to     
regi/ration s]vice fees4 7e7            
,submissions ) data & requir+ data      
review are subject to regi/ration s]vice
 fees4 7#e7 ,am5dm5t applications to add
 ! new use7s7 to regi/]$ product labels 
are cov]$ by ! base fee = ! new use7s74 
,all items 9 ! cov]$ application mu/ be 
submitt$ toge!r 9 "o package4 ,ea*      
application = an additional new product 
regi/ration & new in]t approval7s7 t is 
submitt$ 9 ! new use application package
 is subject to ! regi/ration s]vice fee 
= a new product or a new in]t approval4 
,h[ev]1 if a new use application only   
proposes to regi/] ! new use = a new    
product & !re are no am5dm5ts 9 !       
application1 !n review ( "o new product 
application is cov]$ by ! new use fee4  
,all su* associat$ applications t are   
submitt$ toge!r w be subject to ! new   
use decision review "t4 ,any application

 = a new product or an am5dm5t to !     
propos$ label+ 7a7 submitt$ subsequ5t to
 submission ( ! new use application &   
7b7 prior to conclusion ( its decision  
review "t & 7c7 conta9+ ! same new uses1
 w be deem$ a sep>ate new-use           
application1 subject to a sep>ate       
regi/ration s]vice fee & new decision   
review "t = a new use4 ,if ! new-use    
application includes non-food 7indoor   
&_/or outdoor71 & food 7outdoor &_/or   
indoor7 uses1 ! appropriate fee is due =
 ea* type ( new use & ! longe/ decision 
review "t applies to all ( ! new uses   
reque/$ 9 ! application4 ,any in=mation 
t 7a7 0 nei!r reque/$ nor requir$ by !  
,ag5cy1 & 7b7 is submitt$ by ! applicant
 at ! applicant's initiative to support 
! application aft] completion ( !       
te*nical defici5cy scre51 & 7c7 is n    
itself a cov]$ regi/ration application1 
mu/ be assess$ #be ( ! full regi/ration 
s]vice fee = ! new use application4 7#f7
 ,:]e ! action involves approval ( a new
 or am5d$ label1 on or be=e ! end date (

 ! decision review "t1 ! ,ag5cy %all    
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 

bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 ,b#fijadb,new active       
+r$i5t2 food or non-food use4 7#b77f7 #g
 #b1eed ,b#gjjadc ,exp]im5tal ,use      
,p]mit application2 new active +r$i5t or
 new use4 7#f7 #ga1bgh ,b#gjaadd ,ext5d 
or am5d ,exp]im5tal ,use ,p]mit4 7#f7   
#da1bgh ,b#gajade ,new product2 regi/]$ 
s\rce ( active +r$i5t7s72 id5tical or   
sub/antially simil> 9 composition & use 
to a regi/]$ product2 no *ange 9 an     
e/abli%$ tol]ance or tol]ance exemption4
 ,no data review1 or only product       
*emi/ry data2 cite-all data citation1 or
 selective data citation :]e applicant  
owns all requir$ data or au?orization f 
data own] is demon/rat$4 ,category      
includes #ajj re-package ( regi/]$      
end-use or manufactur+-use product t    
requires no data submission or data     
matrix4 7#c77f7 #d #a1bgh ,b#gbjadf ,new
 product2 regi/]$ s\rce ( active        
+r$i5t7s72 requires3 #a7 submission (   
product specific data2 or #b7 citation (

 previ\sly review$ & accept$ data2 or   
#c7 submission or citation ( data g5]at$
 at gov]nm5t exp5se2 or #d7 submission  
or citation ( a sci5tifically-s\nd      
rationale bas$ on publicly available    
lit]ature or o!r relevant in=mation t   
addresses ! data requirem5t2 or #e7     
submission ( a reque/ = a data          
requirem5t to be waiv$ support$ by a    
sci5tifically-s\nd rationale expla9+ :y 
! data requirem5t does n apply4         
7#c77f7ea1bgh ,b#gbaadg ,new product2   
unregi/]$ s\rce ( active +r$i5t4        
7#c77f7gb1fgf ,b#gbbadh,new use &_/or   
am5dm5t2 petition to e/abli% a tol]ance 
or tol]ance exemption4 7#d77e77f7gb1dgg 
,b#gcjadi,label am5dm5t requir+ data    
submission4 7#d77f7ea1bgh ,,table #af4  
-- ,,biope/icides ,,division -- ,,o!r   
,,actions ,,epa ,no4,new ,,cr           
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
77 7#a7 ,a decision review "t t w\ld    
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  

next bus9ess day4                       
,b#fadaej,pre-application2 ,conditional 
,rul+ on rationales = address+ a data   
requirem5t 9 lieu ( data2               
applicant-initiat$2 applies to "o       
rationale at a "t4#c #b1ecj             
,b#faeaea,rebuttal ( ag5cy review$      
protocol1 applicant initiat$4#cb1ecj    
,b#fhbaeb,protocol review2 applicant    
initiat$2 excludes "t = ,,hsrb review4  
#cb1dcb ,,table #ag4 -- ,,biope/icides  
,,division -- ,,pip ,,epa ,no4,new ,,cr 
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
77 7#a7 ,a decision review "t t w\ld    
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day4 7#b7 ,new ,,pip  a    
,,pip ) an active +r$i5t t has n be5    
regi/]$4 7#c7 ,regi/]$ ,,pip  a ,,pip ) 
an active +r$i5t t is curr5tly regi/]$4 
7#d7 ,transf] regi/]$ ,,pip ?r\gh       
conv5tional bre$+ = new food_/fe$ use1  
su* z f field corn to sweet corn4 7#e7  
,! sci5tific data involv$ 9 ?is category

 are complex4 ,,epa (t5 seeks te*nical  
advice f ! ,sci5tific ,advisory ,panel  
on risks t pe/icides pose to wildlife1  
f>m work]s1 pe/icide applicators1       
non-t>get species1 z well z insect      
resi/ance1 & novel sci5tific issues     
surr\nd+ new te*nologies4 ,! sci5ti/s ( 
! ,,sap nei!r make nor recomm5d policy  
decisions4 ,!y provide advice on !      
sci5ce us$ to make ^! decisions4 ,_!    
advice is invaluable to ! ,,epa z x     
/rives to protect humans & ! environm5t 
f risks pos$ by pe/icides4 ,due to ! "t 
x takes to s*$ule & prep>e = meet+s ) ! 
,,sap1 additional "t & co/s are ne$$4   
7#f7 ,regi/]$ ,p,i,ps /ack$ ?r\gh       
conv5tional bre$+4 7#g7 ,deploym5t ( a  
regi/]$ ,,pip ) a diff]5t ,,irm plan    
7e4g41 se$ bl5d74 7#h7 ,! negotiat$     
acreage cap w dep5d ^u ,,epa's          
det]m9ation ( ! pot5tial environm5tal   
exposure1 risk7s7 to non-t>get          
organisms1 & ! risk ( t>get$ pe/        
develop+ resi/ance to ! pe/icidal       
sub/ance4 ,! unc]ta9ty ( ^! risks may   

r$uce ! all[able acreage1 bas$ ^u !     
quantity & type ( non-t>get organism    
data submitt$ & ! lack ( insect         
resi/ance managem5t data1 :i* is usually
 n requir$ = se$-increase regi/rations4 
,regi/rants are enc\rag$ to consult )   
,,epa prior to submission ( a           
regi/ration application 9 ?is category4 
7#i7 ,application c be submitt$ prior to
 or concurr5tly ) an application =      
comm]cial regi/ration4 7#aj7 ,= example1
 ,,irm plan modifications t are         
applicant-initiat$4 7#aa7 ,,epa-initiat$
 am5dm5ts %all n be *>g$ fees4 7#ab7    
,:]e ! action involves approval ( a new 
or am5d$ label1 on or be=e ! end date ( 
! decision review "t1 ! ,ag5cy %all     
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x

 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 ,b#gdjaec;,exp]im5tal ,use 
,p]mit application2 no petition =       
tol]ance_/tol]ance exemption4           
,includes3#a4 non-food_/fe$ use7s7 = a  
new 7#b7 or regi/]$ 7#c7 ,,pip 7#ab72b4 
food_/fe$ use7s7 = a new or regi/]$     
,,pip ) crop de/ruct 7#ab72c4 food_/fe$ 

use7s7 = a new or regi/]$ ,,pip 9 :i* an
 e/abli%$ tol]ance_/tol]ance exemption  
exi/s = ! int5d$ use7s74 7#d77ab7f      
#ie1gbd ,b#gdaaed 7new7,exp]im5tal ,use 
,p]mit application2 no petition =       
tol]ance_/tol]ance exemption4           
,includes3#a4 non-food_/fe$ use7s7 = a  
new 7#b7 or regi/]$ 7#c7 ,,pip2#b4      
food_/fe$ use7s7 = a new or regi/]$     
,,pip ) crop de/ruct2#c4 food_/fe$      
use7s7 = a new or regi/]$ ,,pip 9 :i* an
 e/abli%$ tol]ance_/tol]ance exemption  
exi/s = ! int5d$ use7s72,,sap ,review4  
7#ab7 #abaei1ech ,b#gejaee;,exp]im5tal  
,use ,p]mit application2 ) a petition to
 e/abli% a tempor>y or p]man5t          
tol]ance_/tol]ance exemption = ! active 
+r$i5t4 ,includes new food_/fe$ use = a 
regi/]$ 7#c7 ,,pip4 7#d77ab7iabg1fcj    
,b#ggjaef;,exp]im5tal ,use ,p]mit       
application2 new 7#b7 ,,pip2 ) petition 
to e/abli% a tempor>y tol]ance_/tol]ance
 exemption = ! active +r$i5t2 cr$it #ge 
( ,b#gga fee t[>d regi/ration           
application = a new active +r$i5t t     

foll[s2 ,,sap review4 7#e77ab7 #ae      
#aia1ddd ,b#ggaaeg;,exp]im5tal ,use     
,p]mit application2 new 7#b7 ,,pip2 )   
petition to e/abli% a tempor>y          
tol]ance_/tol]ance exemption = ! active 
+r$i5t2 cr$it #ge ( ,b#gga fee t[>d     
regi/ration application = a new active  
+r$i5t t foll[s4 7#ab7ajabg1fcj         
,b#ggbaeh;,application to am5d or ext5d 
an ,exp]im5tal ,use ,p]mit2 no petition 
s9ce ! e/abli%$ tol]ance_/tol]ance      
exemption = ! active +r$i5t is          
unaffect$4 7#ab7cab1gfd                 
,b#ggcaei;,application to am5d or ext5d 
an ,exp]im5tal ,use ,p]mit2 ) petition  
to ext5d a tempor>y tol]ance_/tol]ance  
exemption = ! active +r$i5t4            
7#ab7eca1iaj ,b#ghjafj,regi/ration      
application2 new 7#b7 ,,pip2            
non-food_/fe$4 7#ab7abaei1ecg           
,b#gijafa,regi/ration application2 new  
7#b7 ,,pip2 non-food_/fe$2 ,,sap review4
 7#e77ab7 #ahbbc1cea                    
,b#hjjafb,regi/ration application2 new  
7#b7 ,,pip2 ) petition to e/abli%       

p]man5t tol]ance_/tol]ance exemption = !
 active +r$i5t bas$ on an exi/+ tempor>y
 tol]ance_/tol]ance exemption4          
7#ab7acagb1cjj ,b#hajafc,regi/ration    
application2 new 7#b7 ,,pip2 ) petition 
to e/abli% p]man5t tol]ance_/tol]ance   
exemption = ! active +r$i5t bas$ on an  
exi/+ tempor>y tol]ance_/tol]ance       
exemption4 ,,sap review4                
7#e77ab7aibcf1aad ,b#hbjafd,regi/ration 
application2 new 7#b7 ,,pip2 ) petition 
to e/abli% or am5d a p]man5t            
tol]ance_/tol]ance exemption ( an active
 +r$i5t4 7#ab7aebjd1bjh                 
,b#hdjafe,regi/ration application2 new  
7#b7 ,,pip2 ) petition to e/abli% or    
am5d a p]man5t tol]ance_/tol]ance       
exemption ( an active +r$i5t4 ,,sap     
review4 7#e77ab7babfh1jbb               
,b#heaaff,regi/ration application2 new  
ev5t ( a previ\sly regi/]$ ,,pip active 
+r$i5t7s72 no petition s9ce p]man5t     
tol]ance_/tol]ance exemption is already 
e/abli%$ = ! active +r$i5t7s74          
7#ab7iabg1fcj ,b#hgjafg,regi/ration     

application2 regi/]$ 7#c7 ,,pip2 new    
product2 new use2 no petition s9ce a    
p]man5t tol]ance_/tol]ance exemption is 
already e/abli%$ = ! active +r$i5t7s74  
7#d7 7#ab7ich1bij ,b#hhjafh,regi/ration 
application2 regi/]$ 7#c7 ,,pip2 new    
product or new t]ms ( regi/ration2      
additional data submitt$2 no petition   
s9ce a p]man5t tol]ance_/tol]ance       
exemption is already e/abli%$ = ! active
 +r$i5t7s74 7#f7 7#g7 7#ab7ica1iaj      
,b#hhaafi,regi/ration application2      
regi/]$ 7#c7 ,,pip2 new product or new  
t]ms ( regi/ration2 additional data     
submitt$2 no petition s9ce a p]man5t    
tol]ance_/tol]ance exemption is already 
e/abli%$ = ! active +r$i5t7s74 ,,sap    
review4 7#e77f77g77ab7aeie1gbd ,b#hhbagj
 7new7,regi/ration application2 new 7#b7
 ,,pip1 se$ increase ) negotiat$ acreage
 cap & "t-limit$ regi/ration2 ) petition
 to e/abli% a p]man5t tol]ance_/tol]ance
 exemption = ! active +r$i5t bas$ on an 
exi/+ tempor>y tol]ance_/tol]ance       
exemption2 ,,sap ,review4               

7#h77ab7aeaia1ddd ,b#hhcaga,regi/ration 
application2 new 7#b7 ,,pip1 se$        
increase ) negotiat$ acreage cap &      
"t-limit$ regi/ration2 ) petition to    
e/abli% a p]man5t tol]ance_/tol]ance    
exemption = ! active +r$i5t bas$ on an  
exi/+ tempor>y tol]ance_/tol]ance       
exemption4 7#h7 7#ab7iabg1fcj           
,b#hhdagb,regi/ration application2 new  
7#b7 ,,pip1 se$ increase ) negotiat$    
acreage cap & "t-limit$ regi/ration2 )  
petition to e/abli% a p]man5t           
tol]ance_/tol]ance exemption = ! active 
+r$i5t4 7#h77ab7abaei1ecg               
,b#hheagc,regi/ration application2      
regi/]$ 7#c7 ,,pip1 se$ increase2 bre$+ 
/ack ( previ\sly approv$ ,p,i,ps1 same  
crop2 no petition s9ce a p]man5t        
tol]ance_/tol]ance exemption is already 
e/abli%$ = ! active +r$i5t7s74          
7#i77ab7fca1iaj ,b#hhfagd               
7new7,regi/ration application2 new 7#b7 
,,pip1 se$ increase ) negotiat$ acreage 
cap & "t-limit$ regi/ration2 ) petition 
to e/abli% a p]man5t tol]ance_/tol]ance 

exemption = ! active +r$i5t4 ,,sap      
,review4 7#h7 7#ab7ahbbc1cea            
,b#hijage;,application to am5d a se$    
increase regi/ration2 conv]ts           
regi/ration to comm]cial regi/ration2 no
 petition s9ce p]man5t                  
tol]ance_/tol]ance exemption is already 
e/abli%$ = ! active +r$i5t7s74          
7#ab7ifc1haf ,b#hiaagf;,application to  
am5d a se$ increase regi/ration2 conv]ts
 regi/ration to a comm]cial regi/ration2
 no petition s9ce a p]man5t             
tol]ance_/tol]ance exemption already    
e/abli%$ = ! active +r$i5t7s72 ,,sap    
review4 7#e77ab7aeabg1fcj               
,b#ijjagg;,application to am5d a        
regi/ration1 includ+ actions su* z      
ext5d+ an expiration date1 modify+ an   
,,irm plan1 or add+ an insect to be     
controll$4 7#aj77aa77ab7fab1gfd         
,b#ijaagh;,application to am5d a        
regi/ration1 includ+ actions su* z      
ext5d+ an expiration date1 modify+ an   
,,irm plan1 or add+ an insect to be     
controll$4 ,,sap review4 7#aj7 7#aa7    

7#ab7abgf1egh ,b#ijbagi,,pip ,protocol  
review4#cf1chc ,b#ijcahj;,in]t +r$i5t   
tol]ance exemption2 e4g41 a m>k] su* z  
,,npt ,,ii2 review$ 9 ,,bppd4#ffc1haf   
,b#ijdaha;,import tol]ance or tol]ance  
exemption2 process$ commodities_/food   
only 7in]t or active +r$i5t74#iabg1fcj  
,b#ijeahb 7new7,,sap ,review4#ffc1haf   
,b#ijfahc 7new7,petition to e/abli% a   
tempor>y tol]ance_/tol]ance exemption = 
"o or m active +r$i5ts4#cca1ijg         
,b#ijgahd 7new7,petition to e/abli% a   
tempor>y tol]ance_/tol]ance exemption = 
"o or m active +r$i5ts bas$ on an exi/+ 
tempor>y tol]ance_/tol]ance             
exemption4#cab1gfd ,b#ijhahe            
7new7,petition to e/abli% a tempor>y    
tol]ance_/tol]ance exemption = "o or m  
active +r$i5ts or in]t +r$i5ts4#cdd1fga 
,,table #ah4 -- ,,in]t ,,+r$i5ts ,,epa  
,no4,new ,,cr ,no4,action,decision      
,review ,"t 7,mon?s77#a7 ,regi/ration   
,s]vice ,fee 77 7#a7 ,a decision review 
"t t w\ld o!rwise end on a ,saturday1   
,sunday1 or f$]al holiday1 w be ext5d$  

to end on ! next bus9ess day4 7#b7 ,if  
ano!r cov]$ application is submitt$ t   
dep5ds ^u an application to approve an  
in]t +r$i5t1 ea* application w be       
subject to its respective regi/ration   
s]vice fee4 ,! decision review "t l9e = 
bo? submissions w be ! longe/ ( !       
associat$ applications4 ,if !           
application cov]s multiple +r$i5ts gr\p$
 by ,,epa into "o *emical class1 a s+le 
regi/ration s]vice fee w be assess$ =   
approval ( ^? +r$i5ts4 7#c7 ,if ,,epa   
data rules are am5d$ to newly require   
cle>ance "u section #djh ( ! ,,ffdca =  
an +r$i5t ( an antimicrobial product :]e
 su* +r$i5t 0 n previ\sly subject to su*
 a cle>ance1 !n review ( ! data = su*   
cle>ance ( su* product is n subject to a
 regi/ration s]vice fee = ! tol]ance    
action = two ye>s f ! effective date ( !
 rule4 7#d7 ,any o!r cov]$ application t
 is associat$ ) & dep5d5t on ! ,,hsrb   
review w be subject to its sep>ate      
regi/ration s]vice fee4 ,! decision     
review times = ! associat$ actions run  

concurr5tly1 b w end at ! date ( ! late/
 review "t4 7#e7 ,any o!r cov]$         
application t is associat$ ) & dep5d5t  
on ! ,,sap review w be subject to its   
sep>ate regi/ration s]vice fee4 ,!      
decision review "t = ! associat$ action 
w be ext5d$ by ! decision review "t = ! 
,,sap review4 7#f7 ,an application = a  
new end-use product us+ a s\rce ( active
 +r$i5t t 7a7 is n yet regi/]$ b 7b7 has
 an application p5d+ ) ! ,ag5cy =       
review1 w be consid]$ an application = a
 new product ) an unregi/]$ s\rce (     
active +r$i5t4 7#g7 ,:]e ! action       
involves approval ( a new or am5d$      
label1 on or be=e ! end date ( !        
decision review "t1 ! ,ag5cy %all       
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x

 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 7#h7 ,if a new saf5] is    
submitt$ 9 ! same package z a new active
 +r$i5t1 & t new active +r$i5t is       
det]m9$ to be r$uc$ risk1 !n ! saf5]    
w\ld get ! same r$uc$ timeframe z ! new 
active +r$i5t4 ,i#jjaahf;,approval ( new
 food use in]t +r$i5t4 7#b77c7ac #bg1jjj

 ,i#jjbahg;,am5d curr5tly approv$ in]t  
+r$i5t tol]ance or exemption f tol]ance2
 new data4 7#b7aag1ejj ,i#jjcahh;,am5d  
curr5tly approv$ in]t +r$i5t tol]ance or
 exemption f tol]ance2 no new data4     
7#b7ic1cjh ,i#jjdahi;,approval ( new    
non-food use in]t +r$i5t4 7#b7 #f       
#aa1jbe ,i#jjeaij;,am5d curr5tly approv$
 non-food use in]t +r$i5t ) new use     
patt]n2 new data4 7#b7fe1eac            
,i#jjfaia;,am5d curr5tly approv$        
non-food use in]t +r$i5t ) new use      
patt]n2 no new data4 7#b7cc1cjh         
,i#jjgaib;,approval ( sub/antially      
simil> non-food use in]t +r$i5ts :5     
orig9al in]t is compositionally simil> )
 simil> use patt]n4 7#b7da1fed          
,i#jjhaic;,approval ( new or am5d$      
polym] in]t +r$i5t1 food use4 7#b7ec1gdi
 ,i#jjiaid;,approval ( new or am5d$     
polym] in]t +r$i5t1 non-food use4 7#b7  
#dc1jhg ,i#jajaie,petition to am5d a    
s+le tol]ance exemption descriptor1 or  
s+le non-food use descriptor1 to add    
#aj ,c,a,s,r,ns2 no new data4 7#b7fa1fed

 ,i#jaaaif 7new7,approval ( new food use
 saf5] ) tol]ance or exemption f        
tol]ance4 7#b77h7bdeig1fhc ,i#jabaig    
7new7,approval ( new non-food use saf5]4
 7#b77h7badae1bda ,i#jacaih             
7new7,approval ( additional food use =  
previ\sly approv$ saf5] ) tol]ance or   
exemption f tol]ance4 7#b7aefb1ige      
,i#jadaii 7new7,approval ( additional   
non-food use = previ\sly approv$ saf5]4 
7#b7aebe1afh ,i#jaebjj 7new7,approval ( 
new g5]ic data = previ\sly approv$ food 
use saf5]4 7#b7bdbfi1gbh ,i#jafbja      
7new7,approval ( am5dm5t7s7 to tol]ance 
& label = previ\sly approv$ saf5]4      
7#b7acee1ggf ,,table #ai4 -- ,,ext]nal  
,,review ,,& ,,miscellane\s ,,actions   
,,epa ,no4,new ,,cr ,no4,action,decision
 ,review ,"t 7,mon?s77#a7 ,regi/ration  
,s]vice ,fee 77 7#a7 ,a decision review 
"t t w\ld o!rwise end on a ,saturday1   
,sunday1 or f$]al holiday1 w be ext5d$  
to end on ! next bus9ess day4 7#b7 ,if  
ano!r cov]$ application is submitt$ t   
dep5ds ^u an application to approve an  

in]t +r$i5t1 ea* application w be       
subject to its respective regi/ration   
s]vice fee4 ,! decision review "t l9e = 
bo? submissions w be ! longe/ ( !       
associat$ applications4 ,if !           
application cov]s multiple +r$i5ts gr\p$
 by ,,epa into "o *emical class1 a s+le 
regi/ration s]vice fee w be assess$ =   
approval ( ^? +r$i5ts4 7#c7 ,if ,,epa   
data rules are am5d$ to newly require   
cle>ance "u section #djh ( ! ,,ffdca =  
an +r$i5t ( an antimicrobial product :]e
 su* +r$i5t 0 n previ\sly subject to su*
 a cle>ance1 !n review ( ! data = su*   
cle>ance ( su* product is n subject to a
 regi/ration s]vice fee = ! tol]ance    
action = two ye>s f ! effective date ( !
 rule4 7#d7 ,any o!r cov]$ application t
 is associat$ ) & dep5d5t on ! ,,hsrb   
review w be subject to its sep>ate      
regi/ration s]vice fee4 ,! decision     
review times = ! associat$ actions run  
concurr5tly1 b w end at ! date ( ! late/
 review "t4 7#e7 ,any o!r cov]$         
application t is associat$ ) & dep5d5t  

on ! ,,sap review w be subject to its   
sep>ate regi/ration s]vice fee4 ,!      
decision review "t = ! associat$ action 
w be ext5d$ by ! decision review "t = ! 
,,sap review4 7#f7 ,an application = a  
new end-use product us+ a s\rce ( active
 +r$i5t t 7a7 is n yet regi/]$ b 7b7 has
 an application p5d+ ) ! ,ag5cy =       
review1 w be consid]$ an application = a
 new product ) an unregi/]$ s\rce (     
active +r$i5t4 7#g7 ,:]e ! action       
involves approval ( a new or am5d$      
label1 on or be=e ! end date ( !        
decision review "t1 ! ,ag5cy %all       
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  

by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 7#h7 ,due to l[ fee & %ort 
"t frame ?is category is n eligible =   
small bus9ess waiv]s4 ,gold seal applies
 to "o regi/]$ product4 7#i7 ,?is       
category includes am5dm5ts ! sole       
purpose ( :i* is to add ,df,e 7or       
equival5t t]ms t d n use 8safe0 or      
d]ivatives ( 8safe07 logos to a label4  
,df,e is a volunt>y program4 ,a label   
be>+ a ,df,e logo is n consid]$ an      

,ag5cy endorsem5t because ! +r$i5ts 9 ! 
qualify+ product mu/ meet objective1    
sci5tific crit]ia e/abli%$ & widely     
publiciz$ by ,,epa4 ,m#jjabjb,/udy      
protocol requir+ ,human ,/udies ,review 
,bo>d review z def9$ 9 #dj ,,cfr ,"p #bf
 9 support ( an active +r$i5t4 7#d7i    
#g1ich ,m#jjbbjc;,complet$ /udy requir+ 
,human ,/udies ,review ,bo>d review z   
def9$ 9 #dj ,,cfr ,"p #bf 9 support ( an
 active +r$i5t4 7#d7ig1ich              
,m#jjcbjd;,ext]nal te*nical pe] review (
 new active +r$i5t1 product1 or am5dm5t 
7e4g41 consultation ) ,,fifra ,sci5tific
 ,advisory ,panel7 = an action ) a      
decision timeframe ( less ?an #ab mon?s4
 ,applicant initiat$ reque/ bas$ on a   
requirem5t ( ! ,adm9i/rator1 z def9$ by 
,,fifra  #be7;d71 9 support ( a novel   
active +r$i5t1 or unique use patt]n or  
application te*nology4 ,excludes ,,pip  
active +r$i5ts4 7#e7abfc1ide            
,m#jjdbje;,ext]nal te*nical pe] review (
 new active +r$i5t1 product1 or am5dm5t 
7e4g41 consultation ) ,,fifra ,sci5tific

 ,advisory ,panel7 = an action ) a      
decision timeframe ( great] ?an #ab     
mon?s4 ,applicant initiat$ reque/ bas$  
on a requirem5t ( ! ,adm9i/rator1 z     
def9$ by ,,fifra  #be7;d71 9 support ( a
 novel active +r$i5t1 or unique use     
patt]n or application te*nology4        
,excludes ,,pip active +r$i5ts4 7#e7    
#ahfc1ide ,m#jjebjf,new ,product3       
,comb9ation1 ,conta9s a comb9ation (    
active +r$i5ts f a regi/]$ &_/or        
unregi/]$ s\rce2 conv5tional1           
antimicrobial &_/or biope/icide4        
,requires coord9ation ) o!r regulatory  
divisions to conduct review ( data1     
label &_/or v]ify ! validity ( exi/+    
data z cit$4 ,only exi/+ uses = ea*     
active +r$i5t 9 ! comb9ation product4   
7#f77g7ibb1jej ,m#jjfbjg,reque/ = up to 
#e lett]s ( c]tification 7,gold ,seal7 =
 "o actively regi/]$ product 7excludes  
di/ributor products74 7#h7abgg          
,m#jjgbjh,reque/ to ext5d ,exclusive    
,use ( data z provid$ by ,,fifra        
,section #c7;c77#a77;,f77ii74#abe1eac   

,m#jjhbji,reque/ to grant ,exclusive    
,use ( data z provid$ by ,,fifra        
,section #c7;c77#a77;,f77vi7 = a m9or   
use1 :5 a ,,fifra ,section #b7ll77#b7   
det]m9ation is requir$4#aea1fed         
,m#jjibaj 7new7,non-,,fifra ,regulat$   
,det]m9ation3 ,applicant initiat$1 p]   
product4#db1cfc ,m#jajbaa               
7new7,conditional rul+ on               
pre-application1 product sub/antial     
simil>ity4#db1cfc ,m#jaabab 7new7,label 
am5dm5t to add ! ,df,e logo2 requires   
data review2 no o!r label *anges4       
7#i7dc1fdh  4  #g4 ,agricultural work]  
protection /&>d2 c]tification ( pe/icide
 applicators  7a7 ,9 g5]al ,except z    
provid$ 9 subsection 7b71 dur+ ! p]iod  
beg9n+ on ! date ( enactm5t ( ?is ,act &
 end+ n e>li] ?an ,octob] #a1 #bjba1 !  
,adm9i/rator ( ! ,environm5tal          
,protection ,ag5cy 7ref]r$ to 9 ?is     
section z ! ,adm9i/rator7--  7#a7 %all  
c>ry out-- 7,a7 ! f9al rule ( !         
,adm9i/rator entitl$ ,pe/icides2        
,agricultural ,work] ,protection ,/&>d  

,revisions 7#hj ,f$4 ,reg4 #fgdif       
7,novemb] #b1 #bjae772 &  7,b7 ! f9al   
rule ( ! ,adm9i/rator entitl$           
,pe/icides2 ,c]tification ( ,pe/icide   
,applicators 7#hb ,f$4 ,reg4 #ieb       
7,janu>y #d1 #bjag772 &  7#b7 %all n    
revise or develop revisions to ! rules  
describ$ 9 subp>agraphs 7,a7 & 7,b7 (   
p>agraph 7#a74  7b7 ,exceptions ,prior  
to ,octob] #a1 #bjba1 ! ,adm9i/rator may
 propose1 & aft] a notice & public      
comm5t p]iod ( n less ?an #ij days1     
promulgate revisions to ! f9al rule     
describ$ 9 subsection 7a77#a77;,a7      
address+ application exclusion zones "u 
"p #agj ( title #dj1 ,code ( ,f$]al     
,regulations1 consi/5t ) ! ,f$]al       
,insecticide1 ,fungicide1 & ,rod5ticide 
,act 7#g ,u4,s4,c4 #acf et seq474  7c7  
,,gao report ,! ,comptroll] ,g5]al ( !  
,unit$ ,/ates %all--  7#a7 conduct a    
/udy on ! use ( ! designat$             
repres5tative1 includ+ ! effect ( t use 
on ! availability ( pe/icide application
 & haz>d in=mation & work] heal? &      

safety2 &  7#b7 n lat] ?an ,octob] #a1  
#bjba1 make publically available a      
report describ+ ! /udy "u p>agraph 7#a71
 includ+ any recomm5dations to prev5t ! 
misuse ( pe/icide application & haz>d   
in=mation1 if t misuse is id5tifi$4     
,cl]k4