,,ii  #aaf? ,,congress  #b;d ,session   
,s4 #cafa  ,,9 ,,! ,,s5ate ,,( ,,!      
,,unit$ ,,/ates  ,janu>y #h1 #bjbj,ms4  
,w>r5 7= h]self1 ,mr4 ,m>key1 ,ms4      
,baldw91 ,ms4 ,hirono1 ,mr4 ,van ,holl51
 ,mr4 ,c>d91 ,mr4 ,book]1 ,mr4 ,casey1  
,mr4 ,s&]s1 ,mr4 ,ka9e1 ,ms4 ,h>ris1    
,mr4 ,:iteh\se1 & ,mr4 ,murphy7         
introduc$ ! foll[+ bill2 :i* 0 read     
twice & ref]r$ to ! ,committee on       
,heal?1 ,education1 ,labor1 & ,p5sions  
,a ,,bill  ,to e/abli% ! 8,biom$ical    
,innovation ,fund01 & = o!r purposes4   
#a4 ,%ort title ,?is ,act may be cit$ z 
! ,national ,biom$ical ,rese>* ,act4    
#b4 ,def9itions ,9 ?is ,act3 7#a7       
,discretion>y appropriations ,! t]m     
discretion>y appropriations has ! mean+ 
giv5 su* t]m 9 section #bej ( ! ,balanc$
 ,budget & ,em]g5cy ,deficit ,control   
,act ( #aihe 7#b ,u4,s4,c4 #ijj74  7#b7 
,fund ,! t]m ,fund means ! ,biom$ical   
,innovation ,fund e/abli%$ "u section   
#c7;a74  7#c7 ,m9imum am\nt ,! t]m      
m9imum am\nt1 ) respect to ! applicable 

entity & = an applicable fiscal ye>--   
7,a7 means ! am\nt equal to ! greate/   
am\nt ( discretion>y appropriations     
appropriat$ to su* entity = a fiscal ye>
 dur+ ! p]iod beg9n+ ) fiscal ye> #bjbj 
& end+ ) ! fiscal ye> be=e ! applicable 
fiscal ye>2 &  7,b7 does n include-- 7i7
 any r$uction 9 an appropriation "u a   
seque/ration ord] issu$ "u ! ,balanc$   
,budget & ,em]g5cy ,deficit ,control    
,act ( #aihe 7#b ,u4,s4,c4 #ijj et      
seq472  7ii7 am\nts collect$ by !       
,secret>y ( ,heal? & ,human ,s]vices "u 
sub*apt] ,c ( *apt] ,,vii ( ! ,f$]al    
,food1 ,drug1 & ,cosmetic ,act 7#ba     
,u4,s4,c4 #cgi;f et seq472  7iii7 am\nts
 di/ribut$ "u section #c7;c77#b72 or    
7iv7 am\nts appropriat$ "u a supplem5tal
 or em]g5cy appropriation ,act4  #c4    
,biom$ical ,innovation ,fund  7a7       
,e/abli%m5t ,!re is e/abli%$ 9 !        
,treasury ( ! ,unit$ ,/ates a fund to be
 kn[n z ! ,biom$ical ,innovation ,fund1 
to be adm9i/]$ by ! ,secret>y ( !       
,treasury1 consi/+ (-- 7#a7 ! am\nts    

transf]r$ to ! ,fund "u subsection 7b72 
&  7#b7 any int]e/ e>n$ on ! inve/m5t ( 
su* am\nts "u subsection 7d74  7b7      
,commitm5t to biom$ical innovation ,n   
lat] ?an ,septemb] #a1 #bjbj1 & e ye>   
!reaft] ?r\gh #bjbi1 ! ,secret>y ( !    
,treasury %all transf] #aj1jjj1jjj1jjj f
 ! g5]al fund ( ! ,treasury into !      
,fund4  7c7 ,di/ribution ( am\nts  7#a7 
,calculation ( annual fund am\nt ,=     
fiscal ye> #bjbj & ea* fiscal ye>       
!reaft]1 n lat] ?an #ae days aft] !     
latt] ( ! date ( enactm5t ( an          
appropriation ,act mak+ full fiscal ye> 
appropriations = su* fiscal ye> to !    
entity describ$ 9 p>agraph 7#b77;,a7 & !
 date ( enactm5t ( an appropriation ,act
 mak+ full fiscal ye> appropriations =  
su* fiscal ye> to ! entity describ$ 9   
p>agraph 7#b77;,b71 ! ,secret>y ( !     
,treasury %all calculate ! total am\nt 9
 ! ,fund t is available to be di/ribut$ 
= su* fiscal ye> 9 accordance ) p>agraph
 7#b74  7#b7 ,di/ribution ( am\nts 9 !  
,fund ,subject to ! o!r provisions ( ?is

 section1 n lat] ?an #cj days aft] a    
calculation is made "u p>agraph 7#a7 = a
 fiscal ye>1 ! ,secret>y ( ! ,treasury  
%all di/ribute ! am\nt available to be  
di/ribut$ = su* fiscal ye> to ea* ( !   
foll[+ entities3  7,a7 ,! ,national     
,in/itutes ( ,heal?4  7,b7 ,! ,food &   
,drug ,adm9i/ration4  7#c7 ,ratio ,!    
am\nt t ! ,secret>y ( ! ,treasury       
di/ributes to an entity describ$ 9      
subp>agraph 7,a7 or 7,b7 ( p>agraph 7#b7
 dur+ a fiscal ye> %all be> ! same      
relation to ! total am\nt calculat$ "u  
p>agraph 7#a7 = su* fiscal ye> z ! am\nt
 ( discretion>y appropriations          
appropriat$ to su* entity = su* fiscal  
ye> be>s to ! total am\nt ( discretion>y
 appropriations appropriat$ to !        
entities describ$ 9 subp>agraphs 7,a7 & 
7,b7 ( p>agraph 7#b7 = su* fiscal ye>4  
7#d7 ,requirem5ts = di/ribution  7,a7 ,9
 g5]al ,! ,secret>y ( ! ,treasury %all  
di/ribute am\nts 9 ! ,fund dur+ a fiscal
 ye> 9 accordance ) p>agraph 7#b7 only  
if--  7i7 ! discretion>y appropriations 

= ! entity describ$ 9 p>agraph 7#b77;,a7
 is great] ?an ! applicable m9imum am\nt
 = su* entity = su* fiscal ye>2 &  7ii7 
! discretion>y appropriations = ! entity
 describ$ 9 p>agraph 7#b77;,b7 is great]
 ?an ! applicable m9imum am\nt = su*    
entity = su* fiscal ye>4  7,b7          
,subsequ5t law impact+ di/ribution  7i7 
,bel[ m9imum am\nt ,if a law is enact$  
or becomes effective aft] am\nts are    
appropriat$ to ea* entity describ$ 9    
subp>agraph 7,a7 or 7,b7 ( p>agraph 7#b7
 = a fiscal ye> & su* law decreases !   
am\nt appropriat$ to ei!r su* entity =  
su* fiscal ye> f an am\nt t is great]   
?an ! applicable m9imum am\nt to an     
am\nt t is less ?an or equal to su*     
m9imum am\nt1 any am\nts t 7 di/ribut$  
by ! ,secret>y ( ! ,treasury "u p>agraph
 7#b7 %all rema9 s di/ribut$ = su*      
fiscal ye>4  7ii7 ,above m9imum am\nt   
,if a law is enact$ or becomes effective
 aft] am\nts are appropriat$ = a fiscal 
ye> to ea* entity describ$ 9 subp>agraph
 7,a7 or 7,b7 ( p>agraph 7#b7 & su* law 

increases ! am\nt appropriat$ to ei!r   
su* entity = su* fiscal ye> f an am\nt t
 is less ?an or equal to ! m9imum am\nt 
to an am\nt t is great] ?an su* m9imum  
am\nt1 & all o!r conditions =           
di/ribution "u ?is p>agraph are met = ! 
fiscal ye>1 ! am\nts 9 ! ,fund %all be  
di/ribut$ by ! ,secret>y ( ! ,treasury  
"u p>agraph 7#b7 = su* fiscal ye>4  7,c7
 ,failure to meet requirem5ts ,if !     
requirem5ts "u subp>agraph 7,a7 are n   
met dur+ a fiscal ye>1 am\nts 9 ! ,fund 
%all--  7i7 n be di/ribut$ "u p>agraph  
7#b72 &  7ii7 rema9 9 ! ,fund1 e>n+     
int]e/ 9 accordance ) subsection 7d71   
until su* requirem5ts1 or ! conditions  
"u subsection 7f71 are met dur+ a fiscal
 ye>4  7#e7 ,allocations  7,a7 ,9 g5]al 
,if am\nts are di/ribut$ "u p>agraph    
7#b7 dur+ a fiscal ye>1 ( ! am\nts s    
di/ribut$--  7i7 #bj p]c5t %all become  
available = obligation dur+ ! fiscal ye>
 dur+ :i* ! di/ribution is made2  7ii7  
#bj p]c5t %all become available =       
obligation dur+ ! fir/ fiscal ye> aft] !

 fiscal ye> dur+ :i* ! di/ribution is   
made2  7iii7 #bj p]c5t %all become      
available = obligation dur+ ! second    
fiscal ye> aft] ! fiscal ye> dur+ :i* ! 
di/ribution is made2  7iv7 #bj p]c5t    
%all become available = obligation dur+ 
! ?ird fiscal ye> aft] ! fiscal ye> dur+
 :i* ! di/ribution is made2 &  7v7 #bj  
p]c5t %all become available = obligation
 dur+ ! f\r? fiscal ye> aft] ! fiscal   
ye> dur+ :i* ! di/ribution is made4     
7,b7 ,availability ( am\nts ,any am\nts 
di/ribut$ "u p>agraph 7#b7 %all rema9   
available until exp5d$4  7#f7 ,au?oriz$ 
uses ,am\nts di/ribut$ "u p>agraph 7#b7 
f ! ,fund %all be us$ to support-- 7,a7 
basic rese>* on ! und]ly+ basis =       
disease to bett] address disease        
prev5tion1 diagnosis1 & treatm5t2  7,b7 
rese>* t fo/]s disruptive innovation1   
su* z-- 7i7 rese>* on diseases or       
conditions = :i* treatm5ts exi/ b are   
inadequate1 includ+ *ronic & acute pa92 
7ii7 rese>* on diseases or conditions = 
:i* !re are unmet m$ical ne$s2  7iii7   

rese>* on diseases or conditions = :i*  
treatm5ts exi/ b ! side effect pr(iles (
 su* treatm5ts limit !rapeutic pot5tial2
  7iv7 rese>* on new approa*es to       
treatm5t ( diseases us+ drugs1 devices1 
or !rapies t1 at ! "t ( di/ribution "u  
p>agraph 7#b71 are n us$ or are und]us$2
 or  7v7 rese>* conduct$ by exp]i5c$    
inve/igators ) a hi/ory ( productive &  
innovative rese>*1 su* t fund+ provides 
long-t]m /ability = su* rese>* & all[s  
su* inve/igators to take great] risks1  
be m adv5tur\s 9 _! l9es ( inquiry1 or  
take ! "t to develop gr\ndbreak+        
te*niques2  7,c7 rese>* relat$ to       
diseases t disproportionally acc\nt =   
,f$]al heal? c>e sp5d+1 includ+ sp5d+ "u
 ! ,m$ic>e program "u title ,,xviii ( ! 
,social ,security ,act 7#db ,u4,s4,c4   
#acie et seq471 ! ,m$icaid program "u   
title ,,xix ( ! ,social ,security ,act  
7#db ,u4,s4,c4 #acif et seq471 ! ,/ate  
,*ildr5's ,heal? ,insurance ,program "u 
title ,,xxi ( ! ,social ,security ,act  
7#db ,u4,s4,c4 #acig;aa et seq471 !     

,,tric>e program "u *apt] #ee ( title   
#aj1 ,unit$ ,/ates ,code1 & hospital c>e
 & m$ical s]vices furni%$ by ! ,dep>tm5t
 ( ,vet]ans ,affairs "u *apt]s #ag & #ah
 ( title #ch1 ,unit$ ,/ates ,code1 su* z
 rese>* relat+ to--  7i7 diseases t     
disproportionally impact old]           
individuals2  7ii7 deg5]ative diseases2 
or  7iii7 *ronic conditions2  7,d7 e>ly 
c>e] sci5ti/s1 su* z ?r\gh--  7i7 aw>d+ 
rese>* project grants t support         
discrete1 specifi$1 & circumscrib$      
projects to be p]=m$ by ! inve/igator 9 
an area repres5t+ ! specific int]e/s &  
compet5cies ( su* inve/igator1 to       
inve/igators--  7,i7 :o are )9 #aj ye>s 
( complet+ a t]m9al rese>* degree2 or   
7,,ii7 :o are )9 #aj ye>s ( complet+ a  
m$ical resid5cy2  7ii7 aw>d+ grants t   
support c>e] developm5t exp]i5ces t lead
 to e>li] rese>* indep5d5ce2 &  7iii7   
aw>d+ grants t support innovative tra9+ 
programs t1 9 addition to sci5tific     
tra9+1 provide additional tra9+ to      
enhance employm5t opportunities1 includ+

 tra9+ 9 managem5t & bus9ess1 to--  7,i7
 graduate /ud5ts2  7,,ii7 po/-doctoral  
fell[s2  7,,iii7 individuals )9 #aj ye>s
 ( complet+ a t]m9al rese>* degree2 or  
7,,iv7 individuals )9 #aj ye>s (        
complet+ a m$ical resid5cy2  7,e7 rese>*
 ef=ts t increase ! pot5tial =          
break?r\gh discov]ies across a div]se   
set ( inve/igators1 rese>* gr\ps1 &     
in/itutions1 :i* may include support+-- 
7i7 inve/igators t are memb]s (         
traditionally und]repres5t$ racial &    
e?nic gr\ps2  7ii7 rese>* gr\ps t are   
div]se 9 size2 or  7iii7 in/itutions t  
increase ! geographic div]sity ( fund+  
provid$ by ! ,national ,in/itutes (     
,heal?2  7,f7 ! developm5t1 review1 &   
po/-m>ket surveillance ( m$ical         
products1 z det]m9$ by ! ,secret>y (    
,heal? & ,human ,s]vices2 &  7,g7 rese>*
 to c>ry out ! goals ( ! /rategy &      
implem5tation plan = advanc+ sci5ce to  
promote public heal? & advance          
innovation 9 regulatory decision mak+   
develop$ "u section #aabd ( ! ,food &   

,drug ,adm9i/ration ,safety &           
,innovation ,act 7#ba ,u4,s4,c4 #cic    
note71 & o!r su* rese>* activities to   
improve ! pr$ictability1 consi/5cy1 &   
effici5cy ( sci5ce-bas$ decision mak+   
conc]n+ m$ical products1 includ+        
facilitat+ ! timely introduction ( new  
te*nologies & me?odologies 9 a safe &   
effective mann] z det]m9$ by ! ,secret>y
 ( ,heal? & ,human ,s]vices4  7#g7      
,int]ag5cy transf]s ,am\nts di/ribut$ f 
! ,fund "u p>agraph 7#b7 %all be        
available ?r\gh int]ag5cy transf] to    
support rese>* conduct$ jo9tly by !     
,national ,in/itutes ( ,heal? or ! ,food
 & ,dug ,adm9i/ration & o!r ,f$]al      
ag5cies4  7d7 ,inve/m5t ( fund balances 
7#a7 ,9 g5]al ,am\nts 9 ! ,fund %all be 
inve/$ 9 int]e/-be>+ obligations ( !    
,unit$ ,/ates 9 ! =m ( special-issue    
securities1 pay+ int]e/ to ! ,fund at   
rates applicable to su* securities1 &   
su* am\nts %all be r$eemable by !       
,secret>y ( ! ,treasury1 = purposes (   
di/ribution "u subsection 7c77#b74  7#b7

 ,di/ribut$ am\nts ,any am\nts t h be5  
di/ribut$ dur+ a fiscal ye> "u          
subsection 7c77#b7 %all n be consid]$   
am\nts 9 ! ,fund = ! purpose ( ?is      
subsection4  7e7 ,prohibition ,am\nts 9 
! ,fund may n be made available = any   
use o!r ?an a use describ$ 9 subsection 
7c77#f74  7f7 ,transf] ,to r$uce !      
deficit  7#a7 ,9 g5]al ,subject to      
p>agraph 7#b71 if am\nts 9 ! ,fund are n
 di/ribut$ by ! ,secret>y ( ! ,treasury 
"u subsection 7c77#b7 = any #c          
consecutive fiscal ye>s1 ! ,secret>y ( !
 ,treasury %all transf] all am\nts 9 !  
,fund to ! g5]al fund ( ! ,treasury =   
purposes ( r$uc+ ! ,f$]al deficit4  7#b7
 ,ye> ( di/ribution ,= purposes (       
p>agraph 7#a71 #c fiscal ye>s %all n be 
deem$ to be consecutive if dur+ any (   
su* ye>s ! ,secret>y ( ! ,treasury has  
transf]r$ all am\nts 9 ! ,fund into !   
g5]al fund ( ! ,treasury 9 accordance ) 
su* p>agraph4  7g7 ,reports  7#a7       
,secret>y reports  7,a7 ,9 g5]al ,n lat]
 ?an ,novemb] #cj1 #bjba1 & e ye>       

!reaft] ?r\gh #bjcj ! ,secret>y ( !     
,treasury %all submit to ! ,committee on
 ,appropriations ( ! ,s5ate1 !          
,committee on ,appropriations ( ! ,h\se 
( ,repres5tatives1 & ! au?oriz+         
committees a report on ! op]ation ( !   
,fund dur+ ! fiscal ye>4  7,b7 ,cont5ts 
,ea* report %all include1 = ! fiscal ye>
 cov]$ by ! report1 ea* ( ! foll[+3 7i7 
,a /atem5t ( ! am\nts1 & ! s\rce ( su*  
am\nts1 transf]r$ to1 cr$it$ to1 &      
deposit$ into ! ,fund4  7ii7 ,a         
description ( any am\nts di/ribut$ "u   
subsection 7c77#b7 dur+ ! fiscal ye>4   
7iii7 ,a /atem5t ( ! balance rema9+ 9 ! 
,fund at ! end ( ! fiscal ye>4  7iv7 ,a 
/atem5t ( ! am\nts inve/$ 9 int]e/-be>+ 
obligations ( ! ,unit$ ,/ates1 & !      
int]e/ e>n$ on su* inve/m5ts4  7#b7     
,ag5cy reports  7,a7 ,annual report+ ,= 
ea* fiscal ye> 9 :i* am\nts are         
available = obligation "u subsection    
7c77#e71 ! ,director ( ! ,national      
,in/itutes ( ,heal? & ! ,commission] (  
,food & ,drugs %all report on ! use (   

su* am\nts 9 ! annual budget submission 
= su* fiscal ye> ( ! ,national          
,in/itutes ( ,heal? & ! ,food & ,drug   
,adm9i/ration1 respectively4  7,b7 ,,nih
 reports ,section #djc7;a7 ( ! ,public  
,heal? ,s]vice ,act 7#db ,u4,s4,c4      
#bhc7;a77 is am5d$ by add+ at ! end !   
foll[+3  7#g7 ,a summ>y ( ! use ( funds 
di/ribut$ "u section #c7;c77#b77;,a7 ( !
 ,national ,biom$ical ,rese>* ,act to ! 
,national ,in/itutes ( ,heal? f !       
,biom$ical ,innovation ,fund1 e/abli%$  
"u section #c7;a7 ( su* ,act1 includ+ ! 
am\nts allocat$ to ea* national rese>*  
in/itute & national c5t]1 ! projects    
fund$ by su* am\nts1 ! accompli%m5ts t h
 result$ f su* am\nts1 & ! goals =      
future use ( su* am\nts4  4  7,c7 ,,fda 
reports ,= ea* #c-ye> p]iod beg9n+ on ! 
date ( enactm5t ( ?is ,act1 if am\nts   
are di/ribut$ "u subsection 7c77#b77;,b7
 to ! ,food & ,drug ,adm9i/ration = any 
fiscal ye> dur+ su* #c-ye> p]iod1 !     
,commission] ( ,food & ,drugs %all      
submit1 to ! ,committee on ,heal?1      

,education1 ,labor1 & ,p5sions ( !      
,s5ate & ! ,committee on ,en]gy &       
,comm]ce ( ! ,h\se ( ,repres5tatives1 a 
report t describes ! allocation ( su*   
am\nts )9 ! ,food & ,drug ,adm9i/ration1
 ! projects fund$ by su* am\nts1 !      
accompli%m5ts t h result$ f su* am\nts1 
& ! goals = future use ( su* am\nts4    
#d4 ,budget>y provisions  7a7           
,discretion>y sp5d+ limits ,! ,(fice (  
,managem5t & ,budget %all n include     
am\nts di/ribut$ "u section #c7;c77#b7  
dur+ a fiscal ye> 9 det]m9+ :e!r !re has
 be5 a brea* ( ! discretion>y sp5d+     
limits "u ! ,balanc$ ,budget & ,em]g5cy 
,deficit ,control ,act ( #aihe 7#b      
,u4,s4,c4 #ijj et seq47 dur+ ! fiscal   
ye>4  7b7 ,budget en=cem5t ,if a bill or
 jo9t resolution1 or am5dm5t !reto or   
conf]5ce report !reon1 if enact$1 w\ld  
cause am\nts to be di/ribut$ "u section 
#c7;c77#b71 ! ,*airp]son ( ! ,committee 
on ! ,budget ( ! ,h\se ( ,repres5tatives
 & ,*airp]son ( ! ,committee on !       
,budget ( ! ,s5ate %all n include !     

budget>y effects ( su* di/ribution =    
purposes ( en=cem5t ( budget>y          
allocations1 aggregates1 levels1 &      
limits 9 ! ,h\se ( ,repres5tatives & !  
,s5ate4  #e4 ,(fsets ,x is ! s5se ( !   
,s5ate t ! am\nts transf]r$ "u section  
#c7;b7 %\ld be (fset completely4