,i  #aafth ,,congress  #ast ,session    
,h4 ,r4 #behj  ,,in ,,the ,,house ,,of  
,,representatives  ,may #h1 #bjai,mr4   
,david ,p4 ,roe of ,tennessee 7for      
himself and ,mr4 ,suozzi7 introduced the
 following bill2 which was referred to  
the ,committee on ,energy and ,commerce1
 and in addition to the ,committee on   
the ,judiciary1 for a period to be      
subsequently determined by the ,speaker1
 in each case for consideration of such 
provisions as fall within the           
jurisdiction of the committee concerned 
,a ,,bill  ,to amend the ,controlled    
,substances ,act to deem drugs or other 
substances that act as mu opioid        
receptor agonists to be in schedule ,i1 
subject to exceptions for substances    
intended for legitimate medical or      
research use1 and for other purposes4   
#a4 ,short title ,this ,act may be cited
 as the ,modernizing ,drug ,enforcement 
,act of #bjai4  #b4 ,drugs or other     
substances that act as mu opioid        
receptor agonists  7a7 ,definitions     

,paragraph 7#ah7 of section #ajb of the 
,controlled ,substances ,act 7#ba       
,u4,s4,c4 #hjb7 is amended to read as   
follows3  7#ah7  7,a7 ,the term opiateor
 opioid-- 7i7 means any drug or other   
substance having an addiction-forming or
 addiction-sustaining liability similar 
to morphine or being capable of         
conversion into a drug having such      
addiction-forming or                    
addiction-sustaining liability2 and     
7ii7 includes any drug or other         
substance that acts as a mu opioid      
receptor agonist4  7,b7 ,the term mu    
opioid receptor is a molecule that when 
bound to1 and activated by1 a mu opioid 
receptor agonist would result in        
analgesia1 euphoria1 addiction1 or      
respiratory depression in the central   
nervous system4  7,c7 ,the term mu      
opioid receptor agonist is a substance  
that when bound to1 and interacting     
with1 the mu opioid receptor1 activates 
the receptor to result in analgesia1    
euphoria1 addiction1 or respiratory     

depression4  4  7b7 ,scheduling ,section
 #bja of the ,controlled ,substances    
,act 7#ba ,u4,s4,c4 #haa7 is amended by 
adding at the end the following3  7k7   
,mu opioid receptor agonists  7#a7 ,in  
general ,effective as of the date of    
enactment of the ,modernizing ,drug     
,enforcement ,act of #bjai1 schedule ,i 
under section #bjb is deemed to include1
 unless specifically exempted or unless 
listed in another schedule1 any chemical
 substances1 including their salts1     
isomers1 and salts of isomers whenever  
the existence of such salts1 isomers1   
and salts of isomers is possible1 that  
act as mu opioid receptor agonists1 and 
any material1 compound1 mixture1 or     
preparation that contains any quantity  
of such substances4  7#b7 ,exceptions ,a
 chemical substance is exempt from      
inclusion in schedule ,i by operation of
 paragraph 7#a7-- 7,a7 if the substance 
is the subject of an approved           
application submitted under subsection  
7b7 or 7j7 of section #eje of the       

,federal ,food1 ,drug1 and ,cosmetic    
,act2  7,b7 to the extent the substance 
is exempt from the provisions of section
 #eje of such ,act relating to new drugs
 because--  7i7 the substance is        
intended solely for investigational use 
as described in section #eje7;i7 of such
 ,act2 and  7ii7 the substance is being 
used exclusively for purposes of a      
clinical trial that is the subject of an
 effective investigational new drug     
application2 or  7,c7 to the extent the 
substance is the subject of a           
nonclinical study by researchers        
qualified by scientific training to     
investigate the safety and effectiveness
 of drugs4  7#c7 ,listing ,not later    
than #ahj days after the date of        
enactment of the ,modernizing ,drug     
,enforcement ,act of #bjai1 the         
,attorney ,general shall update schedule
 ,i in accordance with paragraph 7#a74  
,the ,attorney ,general may list        
substances in schedule ,i pursuant to   
paragraph 7#a7 without regard to the    

process and considerations that are     
otherwise applicable under this section 
for adding1 removing1 or transferring   
controlled substances to1 from1 or among
 the schedules under section #bjb4  4