,9 ! ,s5ate ( ! ,unit$ ,/ates1  ,june   
#bh1 #bjah4  ,am5dm5ts3  ,t ! bill f !  
,h\se ( ,repres5tatives 7,h4,r4 #ajbi7  
entitl$ ,an ,act to am5d ! ,f$]al       
,insecticide1 ,fungicide1 & ,rod5ticide 
,act to improve pe/icide regi/ration &  
o!r activities "u ! ,act1 to ext5d &    
modify fee au?orities1 & = o!r          
purposes41 d pass ) ! foll[+ 7#a7 ,on   
page #b1 l9e #c1 /rike ,pe/icide        
,regi/ration ,enhancem5t ,act ( #bjag & 
ins]t ,pe/icide ,regi/ration ,improvem5t
 ,ext5sion ,act ( #bjah4 7#b7 ,on page  
#b1 l9e#ad & #ae1 /rike #bjag ?r\gh     
#bjbc & ins]t #bjai ?r\gh #bjbc 7#c7 ,on
 page #b1 l9e #bj1 /rike #bjag ?r\gh    
#bjbc & ins]t #bjai ?r\gh #bjbc 7#d7 ,on
 page #c1 l9e #b1 /rike #bjag ?r\gh     
#bjbc & ins]t #bjai ?r\gh #bjbc 7#e7 ,on
 page #c1 l9e #g1 /rike #bjag ?r\gh     
#bjbc & ins]t #bjai ?r\gh #bjbc 7#f7 ,on
 page #c1 l9e #aa1 /rike #bjag ?r\gh    
#bjbc & ins]t #bjai ?r\gh #bjbc 7#g7 ,on
 page #c1 l9e #ac1 /rike #bjbc & ins]t  
#bjbj 7#h7 ,on page #c1 l9e#ag ?r\gh l9e

 #bj1 /rike & ins]t3 7#a7 7,a7 by /rik+ 
! date ( enactm5t ( ?is section & end+  
on ,septemb] #cj1 #bjai & ins]t+ !      
effective date ( ! ,pe/icide            
,regi/ration ,improvem5t ,ext5sion ,act 
( #bjah & end+ on ,septemb] #cj1 #bjbe2 
&  7#i7 ,on page #d1 l9e #d1 /rike #bjbc
 & ins]t #bjbj 7#aj7 ,on page #d1 l9e   
#ad1 aft] ?r\gh ins]t3 ! p]iod at ! end 
( 7#aa7 ,on page #e1 l9e #bj & #ba1     
/rike #bjag ?r\gh #bjbc & ins]t #bjah   
?r\gh #bjbj 7#ab7 ,on page #f1 l9e #h1  
/rike #bjag ?r\gh #bjba & ins]t #bjah   
?r\gh #bjbj 7#ac7 ,on page #g1 l9e #e1  
aft] p[d]s1 ins]t or 7#ad7 ,on page #g1 
l9e #ac & #ad1 /rike ,june #cj1 #bjag & 
ins]t3 #cj days aft] ! effective date ( 
! ,pe/icide ,regi/ration ,improvem5t    
,ext5sion ,act ( #bjah4 7#ae7 ,on page  
#g1 l9e #be1 /rike #bjbj & ins]t #bjai4 
7#af7 ,on page #h1 l9e #ae1 /rike       
"t-to-"t & ins]t "t to "t 7#ag7 ,on page
 #i1 l9e #ae1 /rike #bjag ?r\gh #bjbc & 
ins]t #bjah ?r\gh #bjbj 7#ah7 ,on page  
#aa1 l9e #bj /rikecov]$ application &   

ins]tcov]$ applications 7#ai7 ,on page  
#aa1 /rike l9es #be ?r\gh page #ab ?r\gh
 l9e #aa & ins]t 7,a7 9 subp>agraph     
7,a7-- 7i7 by /rik+ pe/icide            
regi/ration2 &  7ii7 by /rik+ ,octob]   
#a1 #bjac1 & end+ on ,septemb] #cj1     
#bjae & ins]t+ ,octob] #a1 #bjai1 & end+
 on ,septemb] #cj1 #bjba2  7,b7 9       
subp>agraph 7,b7-- 7i7 by /rik+ pe/icide
 regi/ration2 &  7ii7 by /rik+ #bjae ea*
 place x appe>s & ins]t+ #bjba2 &  7#bj7
 ,on page #ad l9e #b /rike #bjbc & ins]t
 #bjbj 7#ba7 ,on page #ad l9e #g /rike  
#bjbc & ins]t #bjbj 7#bb7 ,on page #ad  
l9e #i /rike #bjbc & ins]t #bjbj 7#bc7  
,on page #ad l9e #af /rike ,enhancem5t &
 ins]t ,improvem5t ,ext5sion 7#bd7 ,on  
page #ad l9e #be /rike 7#g ,u4,s4,c4    
#acfw-#h7;f77#a77 & ins]t 7#g ,u4,s4,c4 
#acfw-#h7;f77 7#be7 ,on page #ae l9e #d 
/rike ,enhancem5t & ins]t ,improvem5t   
,ext5sion 7#bf7 ,on page #af l9e #b     
/rike #bjbc & ins]t #bjbj 7#bg7 ,on page
 #ah l9e #ah /rike vector-born public   
heal? pe/s & ins]t inv]tebrate public   

heal? pe/s t may transmit vector-borne  
disease 7#bh7 ,on page #bj l9e #ag /rike
 #bjbc & ins]t #bjbj 7#bi7 ,on page #bj1
 /rike l9es #bb & #bc & ins]t ,fiscal   
ye> #bjbd4--;,dur+ fiscal ye> #bjbd2 &  
7#cj7 ,on page #bj l9e #be /rike #bjbc &
 ins]t #bjbj 7#ca7 ,on page #ba1 /rike  
l9es #d & #e & ins]t ,fiscal ye>        
#bjbe4--;,dur+ fiscal ye> #bjbe2 & 7#cb7
 ,on page #ba l9e #g /rike #bjbc & ins]t
 #bjbj 7#cc7 ,on page #ba l9es #aj & #aa
 /rike #bjai0 & ins]t+ ,septemb] #cj1   
#bjbe4--;,effective ,septemb] #cj1      
#bjbe2 & & ins]t #bjai0 & ins]t+        
,septemb] #cj1 #bjbe4--;,effective      
,septemb] #cj1 #bjbe2 & 7#cd7 ,on page  
#ba l9e #ad /rike #bjbc & ins]t #bjbj   
7#ce7 ,on page #ba l9e #bb ?r\gh page   
#aje to ! end /rike & ins]t3  7#c7      
,s*$ule ( cov]$ applications & o!r      
actions & _! regi/ration s]vice fees    
,subject to p>agraph 7#f71 ! s*$ule (   
regi/ration applications & o!r cov]$    
actions & _! correspond+ regi/ration    
s]vice fees %all be z foll[s3 ,,table   

#a4 -- ,,regi/ration ,,division -- ,,new
 ,,active ,,+r$i5tsepa ,no4,new ,,cr    
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,all reque/s = new
 uses 7food &_/or nonfood7 conta9$ 9 any
 application = a new active +r$i5t or a 
fir/ food use are cov]$ by ! base fee = 
t new active +r$i5t or fir/ food use    
application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   
fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        

associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 

new active +r$i5t or fir/ food use      
application47#c7 ,:]e ! action involves 
approval ( a new or am5d$ label1 on or  
be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 
made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     
support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 

! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4 ,r#jaja,new ,active        
,+r$i5t1 ,food use4 7#b77c7bd #gec1jhb  
,r#jbjb,new ,active ,+r$i5t1 ,food use2 
r$uc$ risk4 7#b77c7ahfbg1efh,r#jdjc,new 
,active ,+r$i5t1 ,food use2 ,exp]im5tal 
,use ,p]mit application2 e/abli%        
tempor>y tol]ance2 submitt$ be=e        
application = regi/ration2 cr$it #de (  
fee t[>d new active +r$i5t application t
 foll[s4 7#c7ahdfb1ejb,r#jfjd,new       
,active ,+r$i5t1 ,non-food use2 outdoor4
 7#b77c7ba #ebc1bje ,r#jgje,new ,active 
,+r$i5t1 ,non-food use2 outdoor2 r$uc$  
risk4 7#b77c7afdcf1jjd,r#jijf,new       
,active ,+r$i5t1 ,non-food use2 outdoor2
 ,exp]im5tal ,use ,p]mit application2   
submitt$ be=e application = regi/ration2
 cr$it #de ( fee t[>d new active +r$i5t 
application t foll[s4                   

7#c7afcbc1fij,r#aajg,new ,active        
,+r$i5t1 ,non-food use2 indoor4         
7#b77c7bjbij1iid,r#abjh,new ,active     
,+r$i5t1 ,non-food use2 indoor2 r$uc$   
risk4 7#b77c7adbdb1die,r#abai,new       
,active ,+r$i5t1 ,non-food use2 indoor2 
,exp]im5tal ,use ,p]mit application2    
submitt$ be=e application = regi/ration2
 cr$it #de ( fee t[>d new active +r$i5t 
application t foll[s4                   
7#c7ahahb1cbg,r#abbaj;,enri*$ isom]7s7 (
 regi/]$ mix$-isom] active +r$i5t4      
7#b77c7ahcag1abh,r#abcaa,new ,active    
,+r$i5t1 ,se$ treatm5t only2 includes   
agricultural & non-agricultural se$s2   
residues n expect$ 9 raw agricultural   
commodities4                            
7#b77c7ahdga1hfa,r#abeab,new ,active    
,+r$i5t1 ,se$ treatm5t2 ,exp]im5tal ,use
 ,p]mit application2 submitt$ be=e      
application = regi/ration2 cr$it #de (  
fee t[>d new active +r$i5t application t
 foll[s4 7#c7afcbc1fij,,table #b4 --    
,,regi/ration ,,division -- ,,new       
,,usesepa ,no4,new ,,cr                 

,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,all reque/s = new
 uses 7food &_/or nonfood7 conta9$ 9 any
 application = a new active +r$i5t or a 
fir/ food use are cov]$ by ! base fee = 
t new active +r$i5t or fir/ food use    
application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   
fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     

+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application47#c7 ,:]e ! action involves 

approval ( a new or am5d$ label1 on or  
be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 
made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     
support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71

 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy47#d7 ,am5dm5t applications  
to add ! new use7s7 to regi/]$ product  
labels are cov]$ by ! base fee = ! new  
use7s74 ,all items 9 ! cov]$ application
 mu/ be submitt$ toge!r 9 "o package4   
,ea* application = an additional new    
product regi/ration & new in]t          
approval7s7 t is submitt$ 9 ! new use   
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,h[ev]1 if a new
 use application only proposes to regi/]
 ! new use = a new product & !re are no 
am5dm5ts 9 ! application1 !n review ( "o
 new product application is cov]$ by !  
new use fee4 ,all su* associat$         
applications t are submitt$ toge!r w be 
subject to ! new use decision review "t4
 ,any application = a new product or an 
am5dm5t to ! propos$ label+ 7a7 submitt$
 subsequ5t to submission ( ! new use    

application & 7b7 prior to conclusion ( 
its decision review "t & 7c7 conta9+ !  
same new uses1 w be deem$ a sep>ate     
new-use application1 subject to a       
sep>ate regi/ration s]vice fee & new    
decision review "t = a new use4 ,if !   
new-use application includes non-food   
7indoor &_/or outdoor71 & food 7outdoor 
&_/or indoor7 uses1 ! appropriate fee is
 due = ea* type ( new use & ! longe/    
decision review "t applies to all ( !   
new uses reque/$ 9 ! application4 ,any  
in=mation t 7a7 0 nei!r reque/$ nor     
requir$ by ! ,ag5cy1 & 7b7 is submitt$  
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre51 & 7c7 is n itself a cov]$        
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new use application4,r#acjac;,fir/ food 
use2 indoor2 food_/food h&l+4 7#b7      
7#c7baaia1ddd,r#adjad;,additional food  
use2 ,indoor2 food_/food h&l+4 7#c7     
7#d7aedd1fgb,r#aejae;,fir/ food use4    

7#b77c7ba #cag1ajd ,r#aeeaf 7new7,fir/  
food use1 ,exp]im5tal ,use ,p]mit       
application2 a4i4 regi/]$ = non-food    
outdoor use4                            
7#c77d7babfd1bec,r#afjag;,fir/ food use2
 r$uc$ risk4                            
7#b77c7afbfd1bec,r#agjah;,additional    
food use4 7#c7                          
7#d7aegi1cdi,r#ageai;,additional food   
uses cov]$ )9 a crop gr\p result+ f !   
conv]sion ( exi/+ approv$ crop gr\p7s7  
to "o or m revis$ crop gr\ps4           
7#c77d7ajff1abd,r#ahjbj;,additional food
 use2 r$uc$ risk4                       
7#c77d7ajff1abd,r#aijba;,additional food
 uses2 #f or m submitt$ 9 "o            
application4 7#c77d7aedgf1jij           
,r#bjjbb;,additional ,food ,use2 #f or m
 submitt$ 9 "o application2 ,r$uc$      
,risk4                                  
7#c77d7ajcif1gdb,r#bajbc;,additional    
food use2 ,exp]im5tal ,use ,p]mit       
application2 e/abli% tempor>y tol]ance2 
no cr$it t[>d new use regi/ration4      
7#c77d7abdh1ihf,r#bbjbd;,additional food

 use2 ,exp]im5tal ,use ,p]mit           
application2 crop de/ruct basis2 no     
cr$it t[>d new use regi/ration4         
7#c77d7fai1hch,r#bcjbe;,additional use2 
non-food2 outdoor4 7#c7                 
7#d7aeca1gac,r#bdjbf;,additional use2   
non-food2 outdoor2 r$uc$ risk4          
7#c77d7ajbf1dbg,r#bejbg;,additional use2
 non-food2 outdoor2 ,exp]im5tal ,use    
,p]mit application2 no cr$it t[>d new   
use regi/ration4                        
7#c77d7fai1hch,r#beabh;,exp]im5tal ,use 
,p]mit application :i* requires no      
*anges to ! tol]ance7s72 non-crop       
de/ruct basis4 7#c7hai1hch,r#bfjbi,new  
use2 non-food2 indoor4 7#c7             
7#d7abae1cag,r#bgjcj,new use2 non-food2 
indoor2 r$uc$ risk4                     
7#c77d7iab1gfd,r#bgaca,new use2         
non-food2 indoor2 ,exp]im5tal ,use      
,p]mit application2 no cr$it t[>d new   
use regi/ration4                        
7#c77d7fi1gbe,r#bgccb;,additional use2  
se$ treatm5t2 limit$ uptake into ,raw   
,agricultural ,commodities2 includes    

crops ) e/abli%$ tol]ances 7e4g41 = soil
 or foli> application72 includes food   
&_/or non-food uses4                    
7#c77d7abej1dde,r#bgdcc;,additional     
uses2 se$ treatm5t only2 #f or m        
submitt$ 9 "o application2 limit$ uptake
 into raw agricultural commodities2     
includes crops ) e/abli%$ tol]ances     
7e4g41 = soil or foli> application72    
includes food &_/or non-food uses4      
7#c77d7 #abcjb1ffc,,table #c4 --        
,,regi/ration ,,division -- ,,import ,,&
 ,,o!r ,,tol]ancesepa ,no4,new ,,cr     
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,all reque/s = new
 uses 7food &_/or nonfood7 conta9$ 9 any
 application = a new active +r$i5t or a 
fir/ food use are cov]$ by ! base fee = 
t new active +r$i5t or fir/ food use    
application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   

fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 

an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application4 7#c7 ,:]e ! action involves
 approval ( a new or am5d$ label1 on or 
be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 
made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     
support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     

label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy47#d7 ,am5dm5t applications  
to add ! revis$ use patt]n7s7 to regi/]$
 product labels are cov]$ by ! base fee 
= ! category4 ,all items 9 ! cov]$      
application mu/ be submitt$ toge!r 9 "o 
package4 ,ea* application = an          
additional new product regi/ration & new
 in]t approval7s7 t is submitt$ 9 !     

am5dm5t application package is subject  
to ! regi/ration s]vice fee = a new     
product or a new in]t approval4 ,h[ev]1 
if an am5dm5t application only proposes 
to regi/] ! am5dm5t = a new product &   
!re are no am5dm5ts 9 ! application1 !n 
review ( "o new product application is  
cov]$ by ! base fee4 ,all su* associat$ 
applications t are submitt$ toge!r w be 
subject to ! category decision review   
"t4,r#bhjcd;,e/abli% import tol]ance2   
new active +r$i5t or fir/ food use4     
7#b7bacai1jgb,r#bijce;,e/abli% ,import  
tol]ance2 ,additional new food          
use4#aefc1haf,r#biacf;,e/abli% import   
tol]ances2 additional food uses2 #f or m
 crops submitt$ 9 "o                    
petition4#aechb1hhf,r#bibcg;,am5d an    
e/abli%$ tol]ance 7e4g41 decrease or    
increase7 &_/or h>monize e/abli%$       
tol]ances ) ,codex ,m,r,ls2 dome/ic or  
import2                                 
applicant-initiat$4#aade1cda,r#bicch;,e/
abli% tol]ance7s7 = inadv]t5t residues 9
 "o crop2                               

applicant-initiat$4#abec1dhc,r#bidci;,e/
abli% tol]ances = inadv]t5t residues2 #f
 or m crops submitt$ 9 "o application2  
applicant-initiat$4#abcbj1hid,r#biedj;,e
/abli% tol]ance7s7 = residues 9 "o      
rotational crop 9 response to a specific
 rotational crop application2 submission
 ( correspond+ label am5dm5ts :i*       
specify ! necess>y plant-back           
re/rictions2 applicant-initiat$4 7#c7   
7#d7aeff1abd,r#bifda;,e/abli% tol]ances 
= residues 9 rotational crops 9 response
 to a specific rotational crop petition2
 #f or m crops submitt$ 9 "o            
application2 submission ( correspond+   
label am5dm5ts :i* specify ! necess>y   
plant-back re/rictions2                 
applicant-initiat$4 7#c7                
7#d7aecif1gdb,r#bigdb;,am5d #f or m     
e/abli%$ tol]ances 7e4g41 decrease or   
increase7 9 "o petition2 dome/ic or     
import2                                 
applicant-initiat$4#aabgb1jcg,r#bihdc;,a
m5d an e/abli%$ tol]ance 7e4g41 decrease
 or increase72 dome/ic or import2       

submission ( correspond+ am5d$ labels   
7requir+ sci5ce review74 7#c7           
7#d7aceh1efe,r#biidd;,am5d #f or m      
e/abli%$ tol]ances 7e4g41 decrease or   
increase72 dome/ic or import2 submission
 ( correspond+ am5d$ labels 7requir+    
sci5ce review74 7#c7                    
7#d7acbhe1bfa,,table #d4 --             
,,regi/ration ,,division -- ,,new       
,,productsepa ,no4,new ,,cr             
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,an application = 
a new end-use product us+ a s\rce (     
active +r$i5t t 7a7 is n yet regi/]$ b  
7b7 has an application p5d+ ) ! ,ag5cy =
 review1 w be consid]$ an application = 
a new product ) an unregi/]$ s\rce (    
active +r$i5t47#c7 ,:]e ! action        
involves approval ( a new or am5d$      
label1 on or be=e ! end date ( !        
decision review "t1 ! ,ag5cy %all       

provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5

 or electronic confirmation ( agreem5t  
to ! ,ag5cy47#d7 ,= ! purposes (        
classify+ propos$ regi/ration actions   
into ,,pria categories1 8pe/7s7 requir+ 
efficacy0 are3 public heal? pe/s li/$ 9 
,,pr ,notice #bjjb-a1 live/ock pe/s     
7e4g4 ,horn flies1 ,/able flies71       
wood-de/roy+ pe/s 7e4g4 t]mites1 c>p5t] 
ants1 wood-bor+ beetles7 & c]ta9        
invasive species 7e4g4 ,asian ,longhorn$
 beetle1 ,em]ald ,a%bor]74 ,?is li/ may 
be updat$_/ref9$ z invasive pe/ ne$s    
arise4 ,to det]m9e ! numb] ( pe/s = !   
,,pria categories1 pe/s h be5 plac$ into
 gr\ps 7g5]al2 e4g41 cockroa*es7 & pe/  
specific 7specifically a te/ species74  
,if seek+ a label claim aga9/ a pe/ gr\p
 7g5]al71 use ! gr\p li/+ bel[ & ea*    
gr\p w c\nt z #a4 ,! g5]al pe/s gr\ps   
are3 mites1 du/ mites1 *igg]s1 ticks1   
h>d ticks1 s(t ticks1 cattle ticks1     
scorpions1 spid]s1 c5tip$es1 lice1      
fleas1 cockroa*es1 k$s1 bot flies1      
screwworms1 fil? flies1 bl[ flies1 h\se 
flies1 fle% flies1 mosquitoes1 bit+     

flies1 horse flies1 /able flies1 de]    
flies1 s& flies1 bit+ midges1 black     
flies1 true bugs1 b$ bugs1 /++ bees1    
wasps1 yell[ jackets1 hornets1 ants     
7exclud+ c>p5t] ants71 fire & h>ve/]    
ants1 wood de/roy+ beetles1 c>p5t] ants1
 t]mites1 subt]ranean t]mites1 dry wood 
t]mites1 arboreal t]mites1 damp wood    
t]mites & invasive species4 ,if seek+ a 
claim aga9/ a specific pe/ )\t a g5]al  
claim !n ea* specific pe/ w c\nt z      
#a4,r#cjjde,new product2 or simil>      
comb9ation product 7already regi/]$7 to 
an id5tical or sub/antially simil> 9    
composition & use to a regi/]$ product2 
regi/]$ s\rce ( active +r$i5t2 no data  
review on acute toxicity1 efficacy or   
,,crp - only product *emi/ry data2      
cite-all data citation1 or selective    
data citation :]e applicant owns all    
requir$ data1 or applicant submits      
specific au?orization lett] f data own]4
 ,category also includes #ajj re-package
 ( regi/]$ end-use or manufactur+-use   
product t requires no data submission   

nor data matrix4                        
7#b77c7da1ehb,r#cjadf,new product2 or   
simil> comb9ation product 7already      
regi/]$7 to an id5tical or sub/antially 
simil> 9 composition & use to a regi/]$ 
product2 regi/]$ s\rce ( active +r$i5t2 
selective data citation only = data on  
product *emi/ry &_/or acute toxicity    
&_/or public heal? pe/ efficacy         
7id5tical data citation & claims to cit$
 product7s771 :]e applicant does n own  
all requir$ data & does n h a specific  
au?orization lett] f data own]4         
7#b77c7da1hig ,r#cajdg,new end-use or   
manufactur+-use product ) regi/]$       
s\rce7s7 ( active +r$i5t7s72 includes   
products conta9+ two or m regi/]$ active
 +r$i5ts previ\sly comb9$ 9 o!r regi/]$ 
products2 excludes products requir+ or  
cit+ an animal safety /udy2 requires    
review ( data package )9 ,,rd only2     
includes data &_/or waiv]s ( data =     
only3 product *emi/ry &_/or acute       
toxicity &_/or *ild resi/ant packag+    
&_/or pe/7s7 requir+ efficacy 7#d7 - =  

up to #c t>get pe/s4                    
7#b77c7gg1cja,r#caddh,new end use       
product conta9+ up to ?ree regi/]$      
active +r$i5ts nev] be=e regi/]$ z ?is  
comb9ation 9 a =mulat$ product2 new     
product label is id5tical or            
sub/antially simil> to ! labels (       
curr5tly regi/]$ products :i* sep>ately 
conta9 ! respective compon5t active     
+r$i5ts2 excludes products requir+ or   
cit+ an animal safety /udy2 requires    
review ( data package )9 ,,rd only2     
includes data &_/or waiv]s ( data =     
only3 product *emi/ry &_/or acute       
toxicity &_/or  *ild resi/ant packag+   
&_/or pe/7s7 requir+ efficacy 7#d7 - =  
up to #c t>get pe/s4                    
7#b77c7hh1fbf,r#caidi,new end use       
product conta9+ up to ?ree regi/]$      
active +r$i5ts nev] be=e regi/]$ z ?is  
comb9ation 9 a =mulat$ product2 new     
product label is id5tical or            
sub/antially simil> to ! labels (       
curr5tly regi/]$ products :i* sep>ately 
conta9 ! respective compon5t active     

+r$i5ts2 excludes products requir+ or   
cit+ an animal safety /udy2 requires    
review ( data package )9 ,,rd only2     
includes data &_/or waiv]s ( data =     
only3 product *emi/ry &_/or acute       
toxicity &_/or  *ild resi/ant packag+   
&_/or pe/7s7 requir+ efficacy 7#d7 - =  
#d to #g t>get pe/s4                    
7#b77c7ajab1fbf,r#cahej 7new7,new end   
use product conta9+ f\r or m regi/]$    
active +r$i5ts nev] be=e regi/]$ z ?is  
comb9ation 9 a =mulat$ product2 new     
product label is id5tical or            
sub/antially simil> to ! labels (       
curr5tly regi/]$ products :i* sep>ately 
conta9 ! respective compon5t active     
+r$i5ts2 excludes products requir+ or   
cit+ an animal safety /udy2 requires    
review ( data package )9 ,,rd only2     
includes data &_/or waiv]s ( data =     
only3 product *emi/ry &_/or acute       
toxicity &_/or *ild resi/ant packag+    
&_/or pe/7s7 requir+ efficacy 7#d7 - =  
up to #c t>get pe/s4                    
7#b77c7iac1beb,r#cbaea 7new7,new end use

 product conta9+ f\r or m regi/]$ active
 +r$i5ts nev] be=e regi/]$ z ?is        
comb9ation 9 a =mulat$ product2 new     
product label is id5tical or            
sub/antially simil> to ! labels (       
curr5tly regi/]$ products :i* sep>ately 
conta9 ! respective compon5t active     
+r$i5ts2 excludes products requir+ or   
cit+ an animal safety /udy2 requires    
review ( data package )9 ,,rd only2     
includes data &_/or waiv]s ( data =     
only3 product *emi/ry &_/or acute       
toxicity &_/or *ild resi/ant packag+    
&_/or pe/7s7 requir+ efficacy 7#d7 - =  
#d to #g t>get pe/s4                    
7#b77c7aaag1beb,r#caeeb,new end-use1    
on-animal product1 regi/]$ s\rce (      
active +r$i5t7s71 ) ! submission ( data 
&_/or waiv]s = only3 animal safety &    
pe/7s7 requir+ efficacy 7#d7 &_/or      
product *emi/ry &_/or acute toxicity    
&_/or  *ild resi/ant packag+4 7#b7      
7#c7ii1hbj,r#cafec 7new7,new end-use or 
manufactur+ product ) regi/]$ s\rce7s7 (
 active +r$i5t7s7 includ+ products      

conta9+ two or m regi/]$ active +r$i5ts 
previ\sly comb9$ 9 o!r regi/]$ products2
 excludes products requir+ or cit+ an   
animal safety /udy2 & requires review ( 
data &_/or waiv]s = only3 product       
*emi/ry &_/or acute toxicity &_/or  *ild
 resi/ant packag+ &_/or pe/7s7 requir+  
efficacy 7#d7 - = great] ?an #c & up to 
#g t>get pe/s4 7#b77c7iaa1cja,r#caged   
7new7,new end-use or manufactur+ product
 ) regi/]$ s\rce7s7 ( active +r$i5t7s7  
includ+ products conta9+ #b or m regi/]$
 active +r$i5ts previ\sly comb9$ 9 o!r  
regi/]$ products2 excludes products     
requir+ or cit+ an animal safety /udy2 &
 requires review ( data &_/or waiv]s =  
only3 product *emi/ry &_/or acute       
toxicity &_/or  *ild resi/ant packag+   
&_/or pe/7s7 requir+ efficacy 7#d7 - =  
great] ?an #g t>get pe/s4               
7#b77c7ajae1cja,r#cbjee,new product2 new
 physical =m2 requires data review 9    
sci5ce divisions4                       
7#b77c7abac1bbf,r#ccaef,new product2    
repack ( id5tical regi/]$ end-use       

product z a manufactur+-use product1 or 
id5tical regi/]$ manufactur+-use product
 z an end use product2 same regi/]$ uses
 only4 7#b77c7cb1ecj,r#ccbeg,new        
manufactur+-use product2 regi/]$ active 
+r$i5t2 unregi/]$ s\rce ( active +r$i5t2
 submission ( completely new g5]ic data 
package2 regi/]$ uses only2 requires    
review 9 ,,rd & sci5ce divisions4       
7#b77c7bdbhc1bae,r#ccceh,new product2   
,,mup or ,end use product ) unregi/]$   
s\rce ( active +r$i5t2 requires sci5ce  
data review2 new physical =m2 etc4      
,cite-all or selective data citation :]e
 applicant owns all requir$ data4       
7#b77c7ajai1hch,r#ccdei,new product2    
,,mup or ,end use product ) unregi/]$   
s\rce ( ! active +r$i5t2 requires sci5ce
 data review2 new physical =m2 etc4     
,selective data citation4               
7#b77c7aabc1ajj,,table #e4 --           
,,regi/ration ,,division --             
,,am5dm5tsepa ,no4,new ,,cr             
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  

777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 7a7 ,,epa-initiat$
 am5dm5ts %all n be *>g$ regi/ration    
s]vice fees4 7b7 ,regi/rant-initiat$    
fa/-track am5dm5ts are to be complet$ )9
 ! timel9es specifi$ 9 ,,fifra ,section 
#c7;c77#c77;,b7 & are n subject to      
regi/ration s]vice fees4 7c7            
,regi/rant-initiat$ fa/-track am5dm5ts  
h&l$ by ! ,antimicrobials ,division are 
to be complet$ )9 ! timel9es specifi$ 9 
,,fifra ,section #c7;h7 & are n subject 
to regi/ration s]vice fees4 7d7         
,regi/rant initiat$ am5dm5ts submitt$ by
 notification "u ,,pr ,notices1 su* z   
,,pr ,notice #ih-aj1 cont9ue "u ,,pr    
,notice timel9es & are n subject to     
regi/ration s]vice fees4 7e7            
,submissions ) data & requir+ data      
review are subject to regi/ration s]vice
 fees47#c7 ,:]e ! action involves       
approval ( a new or am5d$ label1 on or  
be=e ! end date ( ! decision review "t1 

! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 
made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     
support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 

bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy47#d7 ,= ! purposes (        
classify+ propos$ regi/ration actions   
into ,,pria categories1 8pe/7s7 requir+ 
efficacy0 are3 public heal? pe/s li/$ 9 
,,pr ,notice #bjjb-a1 live/ock pe/s     
7e4g4 ,horn flies1 ,/able flies71       
wood-de/roy+ pe/s 7e4g4 t]mites1 c>p5t] 
ants1 wood-bor+ beetles7 & c]ta9        
invasive species 7e4g4 ,asian ,longhorn$
 beetle1 ,em]ald ,a%bor]74 ,?is li/ may 
be updat$_/ref9$ z invasive pe/ ne$s    
arise4 ,to det]m9e ! numb] ( pe/s = !   
,,pria categories1 pe/s h be5 plac$ into
 gr\ps 7g5]al2 e4g41 cockroa*es7 & pe/  
specific 7specifically a te/ species74  
,if seek+ a label claim aga9/ a pe/ gr\p
 7g5]al71 use ! gr\p li/+ bel[ & ea*    
gr\p w c\nt z #a4 ,! g5]al pe/s gr\ps   
are3 mites1 du/ mites1 *igg]s1 ticks1   
h>d ticks1 s(t ticks1 cattle ticks1     
scorpions1 spid]s1 c5tip$es1 lice1      
fleas1 cockroa*es1 k$s1 bot flies1      
screwworms1 fil? flies1 bl[ flies1 h\se 

flies1 fle% flies1 mosquitoes1 bit+     
flies1 horse flies1 /able flies1 de]    
flies1 s& flies1 bit+ midges1 black     
flies1 true bugs1 b$ bugs1 /++ bees1    
wasps1 yell[ jackets1 hornets1 ants     
7exclud+ c>p5t] ants71 fire & h>ve/]    
ants1 wood de/roy+ beetles1 c>p5t] ants1
 t]mites1 subt]ranean t]mites1 dry wood 
t]mites1 arboreal t]mites1 damp wood    
t]mites & invasive species4 ,if seek+ a 
claim aga9/ a specific pe/ )\t a g5]al  
claim !n ea* specific pe/ w c\nt z      
#a4,r#cdjfj;,am5dm5t requir+ data review
 )9 ,,rd 7e4g41 *anges to precaution>y  
label /atem5ts72 includes add+_/modify+ 
pe/7s7 claims = up to #b t>get pe/s1    
excludes products requir+ or cit+ an    
animal safety /udy4                     
7#b77c77d7dd1ihh,r#cdafa 7,new7,am5dm5t 
requir+ data review )9 ,,rd 7e4g41      
*anges to precaution>y label /atem5ts71 
includes add+_/modify+ pe/7s7 claims =  
great] ?an #b t>get pe/s1 excludes      
products requir+ or cit+ an animal      
safety /udy4                            

7#b77c77d7fe1ihh,r#cdefb;,am5d+         
on-animal products previ\sly regi/]$1 ) 
! submission ( data &_/or waiv]s = only3
  animal safety & pe/7s7 requir+        
efficacy 7#d7 &_/or product *emi/ry     
&_/or acute toxicity &_/or  *ild        
resi/ant packag+4                       
7#b77c7gh1hbj,r#cejfc;,am5dm5t requir+  
data review 9 sci5ce divisions 7e4g41   
*anges to ,,rei1 or ,,ppe1 or ,,phi1 or 
use rate1 or numb] ( applications2 or   
add a]ial application2 or modify        
,,gw_/,,sw advisory /atem5t74           
7#b77c7iac1bbf,r#ceafd;,am5dm5t add+ a  
new unregi/]$ s\rce ( active +r$i5t4    
7#b77c7hac1bbf,r#cebfe;,am5dm5t add+    
already approv$ uses2 selective me?od ( 
support2 does n apply if ! applicant    
owns all cit$ data4 7#b7                
7#c7hac1bbf,r#cgaff;,am5dm5t to         
,exp]im5tal ,use ,p]mit2 7does n include
 ext5d+ a p]mit's "t p]iod74            
7#c7faj1jij,,table #f4 -- ,,regi/ration 
,,division -- ,,o!r ,,actionsepa        
,no4,new ,,cr ,no4,action,decision      

,review ,"t 7,mon?s77#a7 ,regi/ration   
,s]vice ,fee 777#a7 ,a decision review  
"t t w\ld o!rwise end on a ,saturday1   
,sunday1 or f$]al holiday1 w be ext5d$  
to end on ! next bus9ess                
day4,r#abdfg;,conditional ,rul+ on      
,pre-application ,/udy ,waiv]s2         
applicant-initiat$4#fb1ecj,r#bgbfh,revie
w ( ,/udy ,protocol applicant-initiat$2 
excludes ,,d>t1 pre-regi/ration         
conf]5ce1 ,rapid ,response review1 ,,dnt
 protocol review1 protocol ne$+ ,,hsrb  
review4#cb1ecj,r#bgefi,rebuttal ( ag5cy 
review$ protocol1 applicant             
initiat$4#cb1ecj,r#cgjgj;,canc]         
reassessm5t2                            
applicant-initiat$4#ahaih1bej,,table #g4
 -- ,,antimicrobials ,,division -- ,,new
 ,,active ,,+r$i5tsepa ,no4,new ,,cr    
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,all reque/s = new

 uses 7food &_/or nonfood7 conta9$ 9 any
 application = a new active +r$i5t or a 
fir/ food use are cov]$ by ! base fee = 
t new active +r$i5t or fir/ food use    
application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   
fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+

 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application47#c7 ,:]e ! action involves 
approval ( a new or am5d$ label1 on or  
be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 
made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     

support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4,a#chjga,new ,active        
,+r$i5t2 ,indirect ,food use2 e/abli%   

tol]ance or tol]ance exemption if       
requir$4 7#b77c7bdacg1hda ,a#cijgb,new  
,active ,+r$i5t2 ,direct ,food use2     
e/abli% tol]ance or tol]ance exemption  
if requir$4 7#b77c7bdbbi1gcc            
,a#dajgc,new ,active ,+r$i5t ,non-food  
use47#b77c7babbi1gcc ,a#dcagd,new       
,active ,+r$i5t1 ,non-food use2 l[-risk4
 7#b77c7abhj1bbe ,,table #h4 --         
,,antimicrobials ,,division -- ,,new    
,,usesepa ,no4,new ,,cr                 
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,all reque/s = new
 uses 7food &_/or nonfood7 conta9$ 9 any
 application = a new active +r$i5t or a 
fir/ food use are cov]$ by ! base fee = 
t new active +r$i5t or fir/ food use    
application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   
fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 

"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   

decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application47#c7 ,if ,,epa data rules   
are am5d$ to newly require cle>ance "u  
section #djh ( ! ,,ffdca = an +r$i5t (  
an antimicrobial product :]e su* +r$i5t 
0 n previ\sly subject to su* a cle>ance1
 !n review ( ! data = su* cle>ance ( su*
 product is n subject to a regi/ration  
s]vice fee = ! tol]ance action = two    
ye>s f ! effective date ( ! rule47#d7   
,:]e ! action involves approval ( a new 
or am5d$ label1 on or be=e ! end date ( 
! decision review "t1 ! ,ag5cy %all     
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   

label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy47#e7 ,am5dm5t applications  
to add ! new use7s7 to regi/]$ product  

labels are cov]$ by ! base fee = ! new  
use7s74 ,all items 9 ! cov]$ application
 mu/ be submitt$ toge!r 9 "o package4   
,ea* application = an additional new    
product regi/ration & new in]t          
approval7s7 t is submitt$ 9 ! new use   
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,h[ev]1 if a new
 use application only proposes to regi/]
 ! new use = a new product & !re are no 
am5dm5ts 9 ! application1 !n review ( "o
 new product application is cov]$ by !  
new use fee4 ,all su* associat$         
applications t are submitt$ toge!r w be 
subject to ! new use decision review "t4
 ,any application = a new product or an 
am5dm5t to ! propos$ label+ 7a7 submitt$
 subsequ5t to submission ( ! new use    
application & 7b7 prior to conclusion ( 
its decision review "t & 7c7 conta9+ !  
same new uses1 w be deem$ a sep>ate     
new-use application1 subject to a       
sep>ate regi/ration s]vice fee & new    
decision review "t = a new use4 ,if !   

new-use application includes non-food   
7indoor &_/or outdoor71 & food 7outdoor 
&_/or indoor7 uses1 ! appropriate fee is
 due = ea* type ( new use & ! longe/    
decision review "t applies to all ( !   
new uses reque/$ 9 ! application4 ,any  
in=mation t 7a7 0 nei!r reque/$ nor     
requir$ by ! ,ag5cy1 & 7b7 is submitt$  
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre51 & 7c7 is n itself a cov]$        
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new use application4,a#ddjge,new ,use1  
,indirect ,food ,use1 e/abli% tol]ance  
or tol]ance exemption4                  
7#b77c77d7baca1iaj;,a#ddagf;,additional 
,indirect food uses2 e/abli% tol]ances  
or tol]ance exemptions if requir$2 #f or
 m submitt$ 9 "o application4           
7#c77d77e7baaad1hgj;,a#dejgg,new use1   
,direct food use1 e/abli% tol]ance or   
tol]ance exemption4                     
7#b77c77d7baie1gbd;,a#deagh;,additional 

,direct food uses2 e/abli% tol]ances or 
tol]ance exemptions if requir$2 #f or m 
submitt$ 9 "o application4              
7#c77d77e7baahb1cce;,a#ejjgi,new use1   
non-food4 7#d77e7abca1iaj;,a#ejahj,new  
use1 non-food2 #f or m submitt$ 9 "o    
application4 7#d77e7aegf1ehc,,table #i4 
-- ,,antimicrobials ,,division -- ,,new 
,,products ,,& ,,am5dm5tsepa ,no4,new   
,,cr ,no4,action,decision ,review ,"t   
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,an application = 
a new end-use product us+ a s\rce (     
active +r$i5t t 7a7 is n yet regi/]$ b  
7b7 has an application p5d+ ) ! ,ag5cy =
 review1 w be consid]$ an application = 
a new product ) an unregi/]$ s\rce (    
active +r$i5t47#c7 ,:]e ! action        
involves approval ( a new or am5d$      
label1 on or be=e ! end date ( !        
decision review "t1 ! ,ag5cy %all       
provide to ! applicant a draft accept$  

label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  

to ! ,ag5cy4 7#d77;a7 ,,epa-initiat$    
am5dm5ts %all n be *>g$ regi/ration     
s]vice fees4 7b7 ,regi/rant-initiat$    
fa/-track am5dm5ts are to be complet$ )9
 ! timel9es specifi$ 9 ,,fifra ,section 
#c7;c77#c77;,b7 & are n subject to      
regi/ration s]vice fees4 7c7            
,regi/rant-initiat$ fa/-track am5dm5ts  
h&l$ by ! ,antimicrobials ,division are 
to be complet$ )9 ! timel9es specifi$ 9 
,,fifra ,section #c7;h7 & are n subject 
to regi/ration s]vice fees4 7d7         
,regi/rant initiat$ am5dm5ts submitt$ by
 notification "u ,,pr ,notices1 su* z   
,,pr ,notice #ih-aj1 cont9ue "u ,,pr    
,notice timel9es & are n subject to     
regi/ration s]vice fees4 7e7            
,submissions ) data & requir+ data      
review are subject to regi/ration s]vice
 fees4 7#e7 ,! applicant mu/ id5tify !  
sub/antially simil> product if opt+ to  
use cite-all or ! selective me?od to    
support acute toxicity data             
requirem5ts47#f7 ,once a submission = a 
new product ) public heal? organisms has

 be5 submitt$ & classifi$ 9 ei!r ,a#edj 
or ,a#eda1 additional organisms submitt$
 = ! same product be=e expiration ( !   
fir/ submission's orig9al decision      
review "t p]iod w result 9              
reclassification ( bo? ! orig9al &      
subsequ5t submission into ! appropriate 
new category bas$ on ! sum ( ! numb] (  
organisms 9 bo? submissions4 ,a         
reclassification w\ld result 9 a new    
,,pria />t date & require additional    
fees to meet ! fee ( ! new category47#g7
 ,once a submission = a label am5dm5t ) 
public heal? organisms has be5 submitt$ 
& classifi$ 9 ei!r ,a#egj or ,a#egc1    
additional organisms submitt$ = ! same  
product be=e expiration ( ! fir/        
submission's orig9al decision review "t 
p]iod w result 9 reclassification ( bo? 
! orig9al & subsequ5t submission into ! 
appropriate new category bas$ on ! sum (
 ! numb] ( organisms 9 bo? submissions4 
,a reclassification w\ld result 9 a new 
,,pria />t date & require additional    
fees to meet ! fee ( ! new              

category4,a#ecjha ,new product1 id5tical
 or sub/antially simil> 9 composition & 
use to a regi/]$ product2 no data review
 or only product *emi/ry data2 cite all 
data citation or selective data citation
 :]e applicant owns all requir$ data2 or
 applicant submits specific au?orization
 lett] f data own]4 ,category also      
includes #ajj re-package ( regi/]$      
end-use or manufactur+ use product t    
requires no data submission nor data    
matrix4 7#b77c7 #d #a1bgh ,a#ecahb ,new 
product2 id5tical or sub/antially simil>
 9 composition & use to a regi/]$       
product2 regi/]$ s\rce ( active +r$i5t3 
selective data citation only = data on  
product *emi/ry &_/or acute toxicity    
&_/or public heal? pe/ efficacy1 :]e    
applicant does n own all requir$ data & 
does n h a specific au?orization lett] f
 data own]4 7#b77c7da1hbd;,a#ecbhc,new  
product2 id5tical or sub/antially simil>
 9 composition & use to a regi/]$       
product2 regi/]$ active +r$i5t2         
unregi/]$ s\rce ( active +r$i5t2        

cite-all data citation except = product 
*emi/ry2 product *emi/ry data submitt$4 
7#b77c7 #ee1ajg;,a#edjhd ,new end use   
product2 ,,fifra #b7mm7 uses only2 up to
 #be public heal? organisms4            
7#b77c77e77f7e #e1ajg ,a#edahe 7new7    
,new end use product2 ,,fifra #b7mm7    
uses only2 #bf-ej public heal?          
organisms4 7#b77c77e77f7gh1ejj;,a#edbhf 
7new7 ,new end use product2 ,,fifra     
#b7mm7 uses only2  #ea public heal?     
organisms4 7#b77c77e7ajae1jjj;,a#eejhg  
,new end-use product2 uses o!r ?an      
,,fifra #b7mm72 non-,,fqpa product4     
7#b77c77e7iac1bbf ,a#efjhh ,new         
manufactur+ use product2 regi/]$ active 
+r$i5t2 selective data citation4        
7#b77c7fab1eif;,a#efehi 7new7 ,new      
manufactur+-use product2 regi/]$ active 
+r$i5t2 unregi/]$ s\rce ( active +r$i5t2
 submission ( new g5]ic data package2   
regi/]$ uses only2 requires sci5ce      
review4 7#b77c7 #abah1bcd;,a#egjij      
,label am5dm5t requir+ data review2 up  
to #be public heal? organisms4          

7#c77d77e77f7dc1hca;,a#egcia 7new7      
,label am5dm5t requir+ data review2     
#bf-ej public heal? organisms4          
7#b77c77e77g7ff1cej;,a#egdib 7new7      
,label am5dm5t requir+ data review2  #ea
 public heal? organisms4                
7#b77c77e77g7iaa1jjj;,a#egbic,new       
,product or am5dm5t requir+ data review 
= risk assessm5t by ,sci5ce ,bran*      
7e4g41 *anges to ,,rei1 or ,,ppe1 or use
 rate74 7#b77c77d7iac1bbf,,table #aj4 --
 ,,antimicrobials ,,division --         
,,exp]im5tal ,,use ,,p]mits ,,& ,,o!r   
,,actionsepa ,no4,new ,,cr              
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,:]e ! action     
involves approval ( a new or am5d$      
label1 on or be=e ! end date ( !        
decision review "t1 ! ,ag5cy %all       
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     

,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4,a#ebjid ,exp]im5tal ,use   

,p]mit application1 non-food use4 7#b7  
#i #f1chc ,a#ebaie,review ( public heal?
 efficacy /udy protocol )9 ,,ad1 p] ,,ad
 ,int]nal ,guidance = ! ,efficacy       
,protocol ,review ,process2 ,code w also
 include review ( public heal? efficacy 
/udy protocol & data review = devices   
mak+ pe/icidal claims2                  
applicant-initiat$2 ,ti]                
#a4dd1gbf;,a#ebbif ,review ( public     
heal? efficacy /udy protocol outside    
,,ad by memb]s ( ,,ad ,efficacy         
,protocol ,review ,exp]t ,panel2 ,code w
 also include review ( public heal?     
efficacy /udy protocol & data review =  
devices mak+ pe/icidal claims2          
applicant-initiat$2 ,ti]                
#b4abab1aef;,a#ecgig 7new7 ,new ,active 
,+r$i5t_/,new ,use1 ,exp]im5tal ,use    
,p]mit application2 ,direct food use2   
,e/abli% tol]ance or tol]ance exemption 
if requir$4 ,cr$it #de ( fee t[>d new   
active +r$i5t_/new use application t    
foll[s4#ah #aec1aef ,a#echih 7new7 ,new 
,active ,+r$i5t_/,new ,use1 ,exp]im5tal 

,use ,p]mit application2 ,indirect food 
use2 ,e/abli% tol]ance or tol]ance      
exemption if requir$ ,cr$it #de ( fee   
t[>d new active +r$i5t_/new use         
application t foll[s4#ahie1gbd;,a#eciii 
7new7 ,new ,active ,+r$i5t_/,new ,use1  
,exp]im5tal ,use ,p]mit application2    
,nonfood use4 ,cr$it #de ( fee t[>d new 
active +r$i5t_/new use application t    
foll[s4#aeib1afc;,a#ebiajj ,am5dm5t to  
,exp]im5tal ,use ,p]mit2 requires data  
review or risk assessm5t4 7#b7 #iaa1dbi 
,a#ebcaja ,review ( protocol o!r ?an a  
public heal? efficacy /udy 7i4e41       
,toxicology or ,exposure                
,protocols74#iab1aef;,a#egaajb ,sci5ce  
reassessm5t3 ,canc] risk1 ref9$         
ecological risk1 &_/or endang]$ species2
 applicant-initiat$4 #ahie1gbd;,a#eccajc
 7new7,exemption f ! requirem5t ( an    
,exp]im5tal ,use ,p]mit4 7#b7           
#db1dhb;,a#ecdajd 7new7 ,rebuttal (     
ag5cy review$ protocol1 applicant       
initiat$4 #dd1gbf;,a#eceaje 7new7       
,conditional ,rul+ on ,pre-application  

,/udy ,waiv] or ,data ,bridg+ ,argum5t2 
applicant-initiat$4 #fb1dji;,a#ecfajf   
7new7,conditional ,rul+ on              
,pre-application ,direct ,food1         
,indirect ,food1 ,nonfood use           
det]m9ation2                            
applicant-initiat$4#db1dhb,,table #aa4  
-- ,,biope/icides ,,division -- ,,new   
,,active ,,+r$i5tsepa ,no4,new ,,cr     
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,all reque/s = new
 uses 7food &_/or nonfood7 conta9$ 9 any
 application = a new active +r$i5t or a 
fir/ food use are cov]$ by ! base fee = 
t new active +r$i5t or fir/ food use    
application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   
fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    

,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor

 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application4 7#c7 ,:]e ! action involves
 approval ( a new or am5d$ label1 on or 
be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  
draft accept$ label1 includ+ any *anges 
made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     
support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  

application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4,b#ehjajg,new active +r$i5t2
 food use2 petition to e/abli% a        
tol]ance4 7#b77c7 #bj #ea1jec ,b#eijajh 
,new active +r$i5t2 food use2 petition  
to e/abli% a tol]ance exemption4        
7#b77c7ahca1iaj;,b#fjjaji ,new active   
+r$i5t2 non-food use4 7#b77c7           
#acai1adf;,b#fajaaj ,new active +r$i5t2 
,exp]im5tal ,use ,p]mit application2    
petition to e/abli% a tempor>y tol]ance 
or tempor>y tol]ance exemption4 7#c7 #aj
 #ab1gfd ,b#faaaaa ,new active +r$i5t2  

,exp]im5tal ,use ,p]mit application2    
petition to e/abli% p]man5t tol]ance    
exemption4 7#c7abab1gfd;,b#fabaab ,new  
active +r$i5t2 no *ange to a p]man5t    
tol]ance exemption4                     
7#b77c7ajag1eej;,b#facaac ,new active   
+r$i5t2 petition to conv]t a tempor>y   
tol]ance or a tempor>y tol]ance         
exemption to a p]man5t tol]ance or      
tol]ance exemption4 7#b77c7aaag1eej     
,b#fbjaad ,new active +r$i5t2           
,exp]im5tal ,use ,p]mit application2    
non-food use includ+ crop de/ruct4      
7#c7gf1chc,,table #ab4 -- ,,biope/icides
 ,,division -- ,,new ,,usesepa ,no4,new 
,,cr ,no4,action,decision ,review ,"t   
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,all reque/s = new
 uses 7food &_/or nonfood7 conta9$ 9 any
 application = a new active +r$i5t or a 
fir/ food use are cov]$ by ! base fee = 
t new active +r$i5t or fir/ food use    

application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   
fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    
,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  

use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor
 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application4 7#c7 ,am5dm5t applications 
to add ! new use7s7 to regi/]$ product  
labels are cov]$ by ! base fee = ! new  
use7s74 ,all items 9 ! cov]$ application
 mu/ be submitt$ toge!r 9 "o package4   
,ea* application = an additional new    
product regi/ration & new in]t          
approval7s7 t is submitt$ 9 ! new use   
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,h[ev]1 if a new

 use application only proposes to regi/]
 ! new use = a new product & !re are no 
am5dm5ts 9 ! application1 !n review ( "o
 new product application is cov]$ by !  
new use fee4 ,all su* associat$         
applications t are submitt$ toge!r w be 
subject to ! new use decision review "t4
 ,any application = a new product or an 
am5dm5t to ! propos$ label+ 7a7 submitt$
 subsequ5t to submission ( ! new use    
application & 7b7 prior to conclusion ( 
its decision review "t & 7c7 conta9+ !  
same new uses1 w be deem$ a sep>ate     
new-use application1 subject to a       
sep>ate regi/ration s]vice fee & new    
decision review "t = a new use4 ,if !   
new-use application includes non-food   
7indoor &_/or outdoor71 & food 7outdoor 
&_/or indoor7 uses1 ! appropriate fee is
 due = ea* type ( new use & ! longe/    
decision review "t applies to all ( !   
new uses reque/$ 9 ! application4 ,any  
in=mation t 7a7 0 nei!r reque/$ nor     
requir$ by ! ,ag5cy1 & 7b7 is submitt$  
by ! applicant at ! applicant's         

initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre51 & 7c7 is n itself a cov]$        
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new use application4 7#d7 ,:]e ! action 
involves approval ( a new or am5d$      
label1 on or be=e ! end date ( !        
decision review "t1 ! ,ag5cy %all       
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        

describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4,b#fcjaae ,fir/ food use2   
petition to e/abli% a tol]ance          
exemption4 7#b77d7 #ac #ab1gfd ,b#fcaaaf
 ,new food use2 petition to am5d an     
e/abli%$ tol]ance4                      
7#c77d7abab1gfd;,b#fdjaag;,fir/ food    
use2 petition to e/abli% a tol]ance4    
7#b77d7 #aiai1adf;,b#fdcaah,new ,food   
use2 petition to am5d an e/abli%$       
tol]ance exemption4 7#c77d7 #aj #ab1gfd 
,b#fdbaai;,fir/ food use2 indoor2       
food_/food h&l+4                        
7#b77d7abca1iaj;,b#fddabj,new use1 no   
*ange to an e/abli%$ tol]ance or        
tol]ance exemption4                     

7#c77d7hab1gfd;,b#fejaba,new use2       
non-food4 7#c77d7gf1chc ,b#fdeabb 7new7 
,new food use2 ,exp]im5tal ,use ,p]mit  
application2 petition to am5d or add a  
tol]ance exemption4                     
7#d7abab1gfd;,b#fdfabc 7new7,new use2   
non-food use includ+ crop de/ruct2      
,exp]im5tal ,use ,p]mit application4    
7#d7 #gf1chc,,table #ac4 --             
,,biope/icides ,,division -- ,,new      
,,productsepa ,no4,new ,,cr             
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,an application = 
a new end-use product us+ a s\rce (     
active +r$i5t t 7a7 is n yet regi/]$ b  
7b7 has an application p5d+ ) ! ,ag5cy =
 review1 w be consid]$ an application = 
a new product ) an unregi/]$ s\rce (    
active +r$i5t47#c7 ,:]e ! action        
involves approval ( a new or am5d$      
label1 on or be=e ! end date ( !        

decision review "t1 ! ,ag5cy %all       
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 

bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4,b#febabd,new product2      
regi/]$ s\rce ( active +r$i5t2 requires 
petition to am5d e/abli%$ tol]ance or   
tol]ance exemption2 requires #a7        
submission ( product specific data2 or  
#b7 citation ( previ\sly review$ &      
accept$ data2 or #c7 submission or      
citation ( data g5]at$ at gov]nm5t      
exp5se2 or #d7 submission or citation ( 
sci5tifically-s\nd rationale bas$ on    
publicly available lit]ature or o!r     
relevant in=mation t addresses ! data   
requirem5t2 or #e7 submission ( a reque/
 = a data requirem5t to be waiv$        
support$ by a sci5tifically-s\nd        
rationale expla9+ :y ! data requirem5t  
does n apply4 7#b77c7 #ac #ab1gfd       
,b#ffjabe ,new product2 regi/]$ s\rce ( 
active +r$i5t7s72 id5tical or           
sub/antially simil> 9 composition & use 
to a regi/]$ product4 ,no data review1  
or only product *emi/ry data2 cite-all  
data citation1 or selective data        

citation :]e applicant owns all requir$ 
data or au?orization f data own] is     
demon/rat$4 ,category includes #ajj     
re-package ( regi/]$ end-use or         
manufactur+-use product t requires no   
data submission or data matrix4 ,=      
microbial pe/icides1 ! active +r$i5t7s7 
mu/ n be re-isolat$4                    
7#b77c7da1bgh;,b#fgjabf ,new product2   
regi/]$ s\rce ( active +r$i5t7s72       
requires3 #a7 submission ( product      
specific data2 or #b7 citation (        
previ\sly review$ & accept$ data2 or #c7
 submission or citation ( data g5]at$ at
 gov]nm5t exp5se2 or #d7 submission or  
citation ( a sci5tifically-s\nd         
rationale bas$ on publicly available    
lit]ature or o!r relevant in=mation t   
addresses ! data requirem5t2 or #e7     
submission ( a reque/ = a data          
requirem5t to be waiv$ support$ by a    
sci5tifically-s\nd rationale expla9+ :y 
! data requirem5t does n apply4 7#b77c7 
#ge1ajg;,b#fgaabg ,new product2         
unregi/]$ s\rce ( active +r$i5t7s72     

requires a petition to am5d an e/abli%$ 
tol]ance or tol]ance exemption2         
requires3 #a7 submission ( product      
specific data2 or #b7 citation (        
previ\sly review$ & accept$ data2 or #c7
 submission or citation ( data g5]at$ at
 gov]nm5t exp5se2 or #d7 submission or  
citation ( a sci5tifically-s\nd         
rationale bas$ on publicly available    
lit]ature or o!r relevant in=mation t   
addresses ! data requirem5t2 or #e7     
submission ( a reque/ = a data          
requirem5t to be waiv$ support$ by a    
sci5tifically-s\nd rationale expla9+ :y 
! data requirem5t does n apply4 7#b77c7 
#ag #ab1gfd ,b#fgbabh ,new product2     
unregi/]$ s\rce ( active +r$i5t7s72     
non-food use or food use requires3 #a7  
submission ( product specific data2 or  
#b7 citation ( previ\sly review$ &      
accept$ data2 or #c7 submission or      
citation ( data g5]at$ at gov]nm5t      
exp5se2 or #d7 submission or citation ( 
a sci5tifically-s\nd rationale bas$ on  
publicly available lit]ature or o!r     

relevant in=mation t addresses ! data   
requirem5t2 or #e7 submission ( a reque/
 = a data requirem5t to be waiv$        
support$ by a sci5tifically-s\nd        
rationale expla9+ :y ! data requirem5t  
does n apply4 7#b77c7aci1aah;,b#fgcabi  
,new product ,,mup_/,,ep2 unregi/]$     
s\rce ( active +r$i5t7s72 citation (    
,te*nical ,grade ,active ,+r$i5t        
7,,tgai7 data previ\sly review$ &       
accept$ by ! ,ag5cy4 ,requires an ,ag5cy
 det]m9ation t ! cit$ data supports !   
new product4 7#b77c7aje1ajg;,b#fgdacj   
,new product ,,mup2 ,repack ( id5tical  
regi/]$ end-use product z a             
manufactur+-use product2 same regi/]$   
uses only4 7#b77c7da1bgh ,b#fgeaca ,new 
,product ,,mup2 regi/]$ s\rce ( active  
+r$i5t2 submission ( completely new     
g5]ic data package2 regi/]$ uses only4  
7#b77c7aji1aah;,b#fgfacb ,new product2 m
 ?an "o active +r$i5t :]e "o active     
+r$i5t is an unregi/]$ s\rce2 product   
*emi/ry data mu/ be submitt$2 requires3 
#a7 submission ( product specific data1 

& #b7 citation ( previ\sly review$ &    
accept$ data2 or #c7 submission or      
citation ( data g5]at$ at gov]nm5t      
exp5se2 or #d7 submission or citation ( 
a sci5tifically-s\nd rationale bas$ on  
publicly available lit]ature or o!r     
relevant in=mation t addresses ! data   
requirem5t2 or #e7 submission ( a reque/
 = a data requirem5t to be waiv$        
support$ by a sci5tifically-s\nd        
rationale expla9+ :y ! data requirem5t  
does n apply4 7#b77c7                   
#aci1aah;,b#fggacc,new end-use non-food 
animal product ) submission ( two or m  
t>get animal safety /udies2 includes    
data &_/or waiv]s ( data = only3 product
 *emi/ry &_/or acute toxicity &_/or     
public heal? pe/ efficacy &_/or animal  
safety /udies &_/or  *ild resi/ant      
packag+4 7#b77c7ajh1hbj,,table #ad4 --  
,,biope/icides ,,division --            
,,am5dm5tsepa ,no4,new ,,cr             
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     

o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 7a7 ,,epa-initiat$
 am5dm5ts %all n be *>g$ regi/ration    
s]vice fees4 7b7 ,regi/rant-initiat$    
fa/-track am5dm5ts are to be complet$ )9
 ! timel9es specifi$ 9 ,,fifra ,section 
#c7;c77#c77;,b7 & are n subject to      
regi/ration s]vice fees4 7c7            
,regi/rant-initiat$ fa/-track am5dm5ts  
h&l$ by ! ,antimicrobials ,division are 
to be complet$ )9 ! timel9es specifi$ 9 
,,fifra ,section #c7;h7 & are n subject 
to regi/ration s]vice fees4 7d7         
,regi/rant initiat$ am5dm5ts submitt$ by
 notification "u ,,pr ,notices1 su* z   
,,pr ,notice #ih-aj1 cont9ue "u ,,pr    
,notice timel9es & are n subject to     
regi/ration s]vice fees4 7e7            
,submissions ) data & requir+ data      
review are subject to regi/ration s]vice
 fees47#c7 ,:]e ! action involves       
approval ( a new or am5d$ label1 on or  
be=e ! end date ( ! decision review "t1 
! ,ag5cy %all provide to ! applicant a  

draft accept$ label1 includ+ any *anges 
made by ! ,ag5cy t diff] f !            
applicant-submitt$ label & relevant     
support+ data review$ by ! ,ag5cy4 ,!   
applicant w notify ! ,ag5cy t !         
applicant ei!r 7a7 agrees to all ( !    
t]ms associat$ ) ! draft accept$ label z
 am5d$ by ! ,ag5cy & reque/s t x be     
issu$ z ! accept$ f9al ,ag5cy-/amp$     
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5

 or electronic confirmation ( agreem5t  
to ! ,ag5cy4,b#fbaacd;,am5dm5t2         
,exp]im5tal ,use ,p]mit2 no *ange to an 
e/abli%$ tempor>y tol]ance or tol]ance  
exemption4 7#c7g #e1ajg                 
,b#fbbace;,am5dm5t2 ,exp]im5tal ,use    
,p]mit2 petition to am5d an e/abli%$ or 
tempor>y tol]ance or tol]ance exemption4
 7#c7aaab1gfd;,b#fdaacf;,am5dm5t ( an   
e/abli%$ tol]ance or tol]ance           
exemption4#acab1gfd;,b#fhjacg ,am5dm5t2 
regi/]$ s\rces ( active +r$i5t7s72 no   
new use7s72 no *anges to an e/abli%$    
tol]ance or tol]ance exemption4         
,requires data submission4 7#b77c7 #e   
#e1ajg ,b#fhaach ,am5dm5t2 unregi/]$    
s\rce ( active +r$i5t7s74 ,requires data
 submission4 7#b77c7gf1jgi;,b#fhcaci    
,label am5dm5t2 requires review_/update 
( previ\s risk assessm5t7s7 )\t data    
submission 7e4g41 label+ *anges to      
,,rei1 ,,ppe1 ,,phi74                   
7#b77c7fe1ajg;,b#fhdadj ,am5d+ non-food 
animal product t includes submission (  
t>get animal safety data2 previ\sly     

regi/]$4 7#b77c7hh1hbj ,b#fheada 7new7  
,am5dm5t2 add a new bio*emical unregi/]$
 s\rce ( active +r$i5t or a new         
microbial production site4 ,requires    
submission ( analysis ( samples data &  
s\rce_/production site-specific         
manufactur+ process description4        
7#c7ee1ajg,,table #ae4 -- ,,biope/icides
 ,,division -- ,,sclpepa ,no4,new ,,cr  
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,all reque/s = new
 uses 7food &_/or nonfood7 conta9$ 9 any
 application = a new active +r$i5t or a 
fir/ food use are cov]$ by ! base fee = 
t new active +r$i5t or fir/ food use    
application & reta9 ! same decision "t  
review p]iod z ! new active +r$i5t or   
fir/ food use application4 ,!           
application mu/ be receiv$ by ! ag5cy 9 
"o package4 ,! base fee = ! category    
cov]s a maximum ( five new products4    

,ea* application = an additional new    
product regi/ration & new in]t approval 
t is submitt$ 9 ! new active +r$i5t     
application package or fir/ food use    
application package is subject to !     
regi/ration s]vice fee = a new product  
or a new in]t approval4 ,all su*        
associat$ applications t are submitt$   
toge!r w be subject to ! new active     
+r$i5t or fir/ food use decision review 
"t4 ,9 ! case ( a new active +r$i5t     
application1 until t new active +r$i5t  
is approv$1 any subsequ5t application = 
ano!r new product conta9+ ! same active 
+r$i5t or an am5dm5t to ! propos$ label+
 w be deem$ a new active +r$i5t         
application1 subject to ! regi/ration   
s]vice fee & decision review "t = a new 
active +r$i5t4 ,9 ! case ( a fir/ food  
use application1 until t fir/ food use  
is approv$1 any subsequ5t application = 
an additional new food use or uses w be 
subject to ! regi/ration s]vice fee &   
decision review "t = a fir/ food use4   
,any in=mation t 7a7 0 nei!r reque/$ nor

 requir$ by ! ,ag5cy1 & 7b7 is submitt$ 
by ! applicant at ! applicant's         
initiative to support ! application aft]
 completion ( ! te*nical defici5cy      
scre5+1 & 7c7 is n itself a cov]$       
regi/ration application1 mu/ be assess$ 
#be ( ! full regi/ration s]vice fee = ! 
new active +r$i5t or fir/ food use      
application4 7#c7 ,an application = a   
new end-use product us+ a s\rce ( active
 +r$i5t t 7a7 is n yet regi/]$ b 7b7 has
 an application p5d+ ) ! ,ag5cy =       
review1 w be consid]$ an application = a
 new product ) an unregi/]$ s\rce (     
active +r$i5t47#d7 7a7 ,,epa-initiat$   
am5dm5ts %all n be *>g$ regi/ration     
s]vice fees4 7b7 ,regi/rant-initiat$    
fa/-track am5dm5ts are to be complet$ )9
 ! timel9es specifi$ 9 ,,fifra ,section 
#c7;c77#c77;,b7 & are n subject to      
regi/ration s]vice fees4 7c7            
,regi/rant-initiat$ fa/-track am5dm5ts  
h&l$ by ! ,antimicrobials ,division are 
to be complet$ )9 ! timel9es specifi$ 9 
,,fifra ,section #c7;h7 & are n subject 

to regi/ration s]vice fees4 7d7         
,regi/rant initiat$ am5dm5ts submitt$ by
 notification "u ,,pr ,notices1 su* z   
,,pr ,notice #ih-aj1 cont9ue "u ,,pr    
,notice timel9es & are n subject to     
regi/ration s]vice fees4 7e7            
,submissions ) data & requir+ data      
review are subject to regi/ration s]vice
 fees47#e7 ,am5dm5t applications to add 
! new use7s7 to regi/]$ product labels  
are cov]$ by ! base fee = ! new use7s74 
,all items 9 ! cov]$ application mu/ be 
submitt$ toge!r 9 "o package4 ,ea*      
application = an additional new product 
regi/ration & new in]t approval7s7 t is 
submitt$ 9 ! new use application package
 is subject to ! regi/ration s]vice fee 
= a new product or a new in]t approval4 
,h[ev]1 if a new use application only   
proposes to regi/] ! new use = a new    
product & !re are no am5dm5ts 9 !       
application1 !n review ( "o new product 
application is cov]$ by ! new use fee4  
,all su* associat$ applications t are   
submitt$ toge!r w be subject to ! new   

use decision review "t4 ,any application
 = a new product or an am5dm5t to !     
propos$ label+ 7a7 submitt$ subsequ5t to
 submission ( ! new use application &   
7b7 prior to conclusion ( its decision  
review "t & 7c7 conta9+ ! same new uses1
 w be deem$ a sep>ate new-use           
application1 subject to a sep>ate       
regi/ration s]vice fee & new decision   
review "t = a new use4 ,if ! new-use    
application includes non-food 7indoor   
&_/or outdoor71 & food 7outdoor &_/or   
indoor7 uses1 ! appropriate fee is due =
 ea* type ( new use & ! longe/ decision 
review "t applies to all ( ! new uses   
reque/$ 9 ! application4 ,any in=mation 
t 7a7 0 nei!r reque/$ nor requir$ by !  
,ag5cy1 & 7b7 is submitt$ by ! applicant
 at ! applicant's initiative to support 
! application aft] completion ( !       
te*nical defici5cy scre51 & 7c7 is n    
itself a cov]$ regi/ration application1 
mu/ be assess$ #be ( ! full regi/ration 
s]vice fee = ! new use application47#f7 
,:]e ! action involves approval ( a new 

or am5d$ label1 on or be=e ! end date ( 
! decision review "t1 ! ,ag5cy %all     
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  

,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4,b#fijadb,new active +r$i5t2
 food or non-food use4 7#b77f7 #g #b1eed
 ,b#gjjadc ,exp]im5tal ,use ,p]mit      
application2 new active +r$i5t or new   
use4 7#f7 #ga1bgh;,b#gjaadd ,ext5d or   
am5d ,exp]im5tal ,use ,p]mit4 7#f7      
#da1bgh;,b#gajade ,new product2 regi/]$ 
s\rce ( active +r$i5t7s72 id5tical or   
sub/antially simil> 9 composition & use 
to a regi/]$ product2 no *ange 9 an     
e/abli%$ tol]ance or tol]ance exemption4
 ,no data review1 or only product       
*emi/ry data2 cite-all data citation1 or
 selective data citation :]e applicant  
owns all requir$ data or au?orization f 
data own] is demon/rat$4 ,category      
includes #ajj re-package ( regi/]$      
end-use or manufactur+-use product t    
requires no data submission or data     
matrix4 7#c77f7 #d #a1bgh ,b#gbjadf ,new
 product2 regi/]$ s\rce ( active        
+r$i5t7s72 requires3 #a7 submission (   

product specific data2 or #b7 citation (
 previ\sly review$ & accept$ data2 or   
#c7 submission or citation ( data g5]at$
 at gov]nm5t exp5se2 or #d7 submission  
or citation ( a sci5tifically-s\nd      
rationale bas$ on publicly available    
lit]ature or o!r relevant in=mation t   
addresses ! data requirem5t2 or #e7     
submission ( a reque/ = a data          
requirem5t to be waiv$ support$ by a    
sci5tifically-s\nd rationale expla9+ :y 
! data requirem5t does n apply4         
7#c77f7ea1bgh;,b#gbaadg ,new product2   
unregi/]$ s\rce ( active +r$i5t4        
7#c77f7gb1fgf;,b#gbbadh,new use &_/or   
am5dm5t2 petition to e/abli% a tol]ance 
or tol]ance exemption4 7#d77e77f7gb1dgg 
,b#gcjadi,label am5dm5t requir+ data    
submission4 7#d77f7ea1bgh,,table #af4 --
 ,,biope/icides ,,division -- ,,o!r     
,,actionsepa ,no4,new ,,cr              
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 

f$]al holiday1 w be ext5d$ to end on !  
next bus9ess                            
day4,b#fadaej,pre-application2          
,conditional ,rul+ on rationales =      
address+ a data requirem5t 9 lieu (     
data2 applicant-initiat$2 applies to "o 
rationale at a "t4#c #b1ecj             
,b#faeaea,rebuttal ( ag5cy review$      
protocol1 applicant                     
initiat$4#cb1ecj;,b#fhbaeb,protocol     
review2 applicant initiat$2 excludes "t 
= ,,hsrb review4 #cb1dcb,,table #ag4 -- 
,,biope/icides ,,division -- ,,pipepa   
,no4,new ,,cr ,no4,action,decision      
,review ,"t 7,mon?s77#a7 ,regi/ration   
,s]vice ,fee 777#a7 ,a decision review  
"t t w\ld o!rwise end on a ,saturday1   
,sunday1 or f$]al holiday1 w be ext5d$  
to end on ! next bus9ess day47#b7 ,new  
,,pip  a ,,pip ) an active +r$i5t t has 
n be5 regi/]$47#c7 ,regi/]$ ,,pip  a    
,,pip ) an active +r$i5t t is curr5tly  
regi/]$47#d7 ,transf] regi/]$ ,,pip     
?r\gh conv5tional bre$+ = new food_/fe$ 
use1 su* z f field corn to sweet        

corn47#e7 ,! sci5tific data involv$ 9   
?is category are complex4 ,,epa (t5     
seeks te*nical advice f ! ,sci5tific    
,advisory ,panel on risks t pe/icides   
pose to wildlife1 f>m work]s1 pe/icide  
applicators1 non-t>get species1 z well z
 insect resi/ance1 & novel sci5tific    
issues surr\nd+ new te*nologies4 ,!     
sci5ti/s ( ! ,,sap nei!r make nor       
recomm5d policy decisions4 ,!y provide  
advice on ! sci5ce us$ to make ^!       
decisions4 ,_! advice is invaluable to !
 ,,epa z x /rives to protect humans & ! 
environm5t f risks pos$ by pe/icides4   
,due to ! "t x takes to s*$ule & prep>e 
= meet+s ) ! ,,sap1 additional "t & co/s
 are ne$$47#f7 ,regi/]$ ,p,i,ps /ack$   
?r\gh conv5tional bre$+47#g7 ,deploym5t 
( a regi/]$ ,,pip ) a diff]5t ,,irm plan
 7e4g41 se$ bl5d747#h7 ,! negotiat$     
acreage cap w dep5d ^u ,,epa's          
det]m9ation ( ! pot5tial environm5tal   
exposure1 risk7s7 to non-t>get          
organisms1 & ! risk ( t>get$ pe/        
develop+ resi/ance to ! pe/icidal       

sub/ance4 ,! unc]ta9ty ( ^! risks may   
r$uce ! all[able acreage1 bas$ ^u !     
quantity & type ( non-t>get organism    
data submitt$ & ! lack ( insect         
resi/ance managem5t data1 :i* is usually
 n requir$ = se$-increase regi/rations4 
,regi/rants are enc\rag$ to consult )   
,,epa prior to submission ( a           
regi/ration application 9 ?is           
category47#i7 ,application c be submitt$
 prior to or concurr5tly ) an           
application = comm]cial                 
regi/ration47#aj7 ,= example1 ,,irm plan
 modifications t are                    
applicant-initiat$47#aa7 ,,epa-initiat$ 
am5dm5ts %all n be *>g$ fees47#ab7 ,:]e 
! action involves approval ( a new or   
am5d$ label1 on or be=e ! end date ( !  
decision review "t1 ! ,ag5cy %all       
provide to ! applicant a draft accept$  
label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 

all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  
to ! ,ag5cy4,b#gdjaec;,exp]im5tal ,use  
,p]mit application2 no petition =       
tol]ance_/tol]ance exemption4           
,includes3#a4 non-food_/fe$ use7s7 = a  
new 7#b7 or regi/]$ 7#c7 ,,pip 7#ab72b4 

food_/fe$ use7s7 = a new or regi/]$     
,,pip ) crop de/ruct 7#ab72c4 food_/fe$ 
use7s7 = a new or regi/]$ ,,pip 9 :i* an
 e/abli%$ tol]ance_/tol]ance exemption  
exi/s = ! int5d$ use7s74 7#d77ab7f      
#ie1gbd ,b#gdaaed 7new7,exp]im5tal ,use 
,p]mit application2 no petition =       
tol]ance_/tol]ance exemption4           
,includes3#a4 non-food_/fe$ use7s7 = a  
new 7#b7 or regi/]$ 7#c7 ,,pip2#b4      
food_/fe$ use7s7 = a new or regi/]$     
,,pip ) crop de/ruct2#c4 food_/fe$      
use7s7 = a new or regi/]$ ,,pip 9 :i* an
 e/abli%$ tol]ance_/tol]ance exemption  
exi/s = ! int5d$ use7s72,,sap ,review4  
7#ab7 #abaei1ech;,b#gejaee;,exp]im5tal  
,use ,p]mit application2 ) a petition to
 e/abli% a tempor>y or p]man5t          
tol]ance_/tol]ance exemption = ! active 
+r$i5t4 ,includes new food_/fe$ use = a 
regi/]$ 7#c7 ,,pip4                     
7#d77ab7iabg1fcj;,b#ggjaef;,exp]im5tal  
,use ,p]mit application2 new 7#b7 ,,pip2
 ) petition to e/abli% a tempor>y       
tol]ance_/tol]ance exemption = ! active 

+r$i5t2 cr$it #ge ( ,b#gga fee t[>d     
regi/ration application = a new active  
+r$i5t t foll[s2 ,,sap review4 7#e77ab7 
#ae #aia1ddd ,b#ggaaeg;,exp]im5tal ,use 
,p]mit application2 new 7#b7 ,,pip2 )   
petition to e/abli% a tempor>y          
tol]ance_/tol]ance exemption = ! active 
+r$i5t2 cr$it #ge ( ,b#gga fee t[>d     
regi/ration application = a new active  
+r$i5t t foll[s4                        
7#ab7ajabg1fcj;,b#ggbaeh;,application to
 am5d or ext5d an ,exp]im5tal ,use      
,p]mit2 no petition s9ce ! e/abli%$     
tol]ance_/tol]ance exemption = ! active 
+r$i5t is unaffect$4                    
7#ab7cab1gfd;,b#ggcaei;,application to  
am5d or ext5d an ,exp]im5tal ,use       
,p]mit2 ) petition to ext5d a tempor>y  
tol]ance_/tol]ance exemption = ! active 
+r$i5t4 7#ab7eca1iaj                    
,b#ghjafj,regi/ration application2 new  
7#b7 ,,pip2 non-food_/fe$4              
7#ab7abaei1ecg;,b#gijafa,regi/ration    
application2 new 7#b7 ,,pip2            
non-food_/fe$2 ,,sap review4 7#e77ab7   

#ahbbc1cea;,b#hjjafb,regi/ration        
application2 new 7#b7 ,,pip2 ) petition 
to e/abli% p]man5t tol]ance_/tol]ance   
exemption = ! active +r$i5t bas$ on an  
exi/+ tempor>y tol]ance_/tol]ance       
exemption4                              
7#ab7acagb1cjj;,b#hajafc,regi/ration    
application2 new 7#b7 ,,pip2 ) petition 
to e/abli% p]man5t tol]ance_/tol]ance   
exemption = ! active +r$i5t bas$ on an  
exi/+ tempor>y tol]ance_/tol]ance       
exemption4 ,,sap review4                
7#e77ab7aibcf1aad;,b#hbjafd,regi/ration 
application2 new 7#b7 ,,pip2 ) petition 
to e/abli% or am5d a p]man5t            
tol]ance_/tol]ance exemption ( an active
 +r$i5t4                                
7#ab7aebjd1bjh;,b#hdjafe,regi/ration    
application2 new 7#b7 ,,pip2 ) petition 
to e/abli% or am5d a p]man5t            
tol]ance_/tol]ance exemption ( an active
 +r$i5t4 ,,sap review4                  
7#e77ab7babfh1jbb;,b#heaaff,regi/ration 
application2 new ev5t ( a previ\sly     
regi/]$ ,,pip active +r$i5t7s72 no      

petition s9ce p]man5t tol]ance_/tol]ance
 exemption is already e/abli%$ = !      
active +r$i5t7s74                       
7#ab7iabg1fcj;,b#hgjafg,regi/ration     
application2 regi/]$ 7#c7 ,,pip2 new    
product2 new use2 no petition s9ce a    
p]man5t tol]ance_/tol]ance exemption is 
already e/abli%$ = ! active +r$i5t7s74  
7#d7 7#ab7ich1bij;,b#hhjafh,regi/ration 
application2 regi/]$ 7#c7 ,,pip2 new    
product or new t]ms ( regi/ration2      
additional data submitt$2 no petition   
s9ce a p]man5t tol]ance_/tol]ance       
exemption is already e/abli%$ = ! active
 +r$i5t7s74 7#f7 7#g7                   
7#ab7ica1iaj;,b#hhaafi,regi/ration      
application2 regi/]$ 7#c7 ,,pip2 new    
product or new t]ms ( regi/ration2      
additional data submitt$2 no petition   
s9ce a p]man5t tol]ance_/tol]ance       
exemption is already e/abli%$ = ! active
 +r$i5t7s74 ,,sap review4               
7#e77f77g77ab7aeie1gbd;,b#hhbagj        
7new7,regi/ration application2 new 7#b7 
,,pip1 se$ increase ) negotiat$ acreage 

cap & "t-limit$ regi/ration2 ) petition 
to e/abli% a p]man5t tol]ance_/tol]ance 
exemption = ! active +r$i5t bas$ on an  
exi/+ tempor>y tol]ance_/tol]ance       
exemption2 ,,sap ,review4               
7#h77ab7aeaia1ddd;,b#hhcaga,regi/ration 
application2 new 7#b7 ,,pip1 se$        
increase ) negotiat$ acreage cap &      
"t-limit$ regi/ration2 ) petition to    
e/abli% a p]man5t tol]ance_/tol]ance    
exemption = ! active +r$i5t bas$ on an  
exi/+ tempor>y tol]ance_/tol]ance       
exemption4 7#h7                         
7#ab7iabg1fcj;,b#hhdagb,regi/ration     
application2 new 7#b7 ,,pip1 se$        
increase ) negotiat$ acreage cap &      
"t-limit$ regi/ration2 ) petition to    
e/abli% a p]man5t tol]ance_/tol]ance    
exemption = ! active +r$i5t4            
7#h77ab7abaei1ecg;,b#hheagc,regi/ration 
application2 regi/]$ 7#c7 ,,pip1 se$    
increase2 bre$+ /ack ( previ\sly approv$
 ,p,i,ps1 same crop2 no petition s9ce a 
p]man5t tol]ance_/tol]ance exemption is 
already e/abli%$ = ! active +r$i5t7s74  

7#i77ab7fca1iaj;,b#hhfagd               
7new7,regi/ration application2 new 7#b7 
,,pip1 se$ increase ) negotiat$ acreage 
cap & "t-limit$ regi/ration2 ) petition 
to e/abli% a p]man5t tol]ance_/tol]ance 
exemption = ! active +r$i5t4 ,,sap      
,review4 7#h7                           
7#ab7ahbbc1cea;,b#hijage;,application to
 am5d a se$ increase regi/ration2       
conv]ts regi/ration to comm]cial        
regi/ration2 no petition s9ce p]man5t   
tol]ance_/tol]ance exemption is already 
e/abli%$ = ! active +r$i5t7s74          
7#ab7ifc1haf;,b#hiaagf;,application to  
am5d a se$ increase regi/ration2 conv]ts
 regi/ration to a comm]cial regi/ration2
 no petition s9ce a p]man5t             
tol]ance_/tol]ance exemption already    
e/abli%$ = ! active +r$i5t7s72 ,,sap    
review4                                 
7#e77ab7aeabg1fcj;,b#ijjagg;,application
 to am5d a regi/ration1 includ+ actions 
su* z ext5d+ an expiration date1 modify+
 an ,,irm plan1 or add+ an insect to be 
controll$4                              

7#aj77aa77ab7fab1gfd;,b#ijaagh;,applicat
ion to am5d a regi/ration1 includ+      
actions su* z ext5d+ an expiration date1
 modify+ an ,,irm plan1 or add+ an      
insect to be controll$4 ,,sap review4   
7#aj7 7#aa7 7#ab7abgf1egh;,b#ijbagi,,pip
 ,protocol                              
review4#cf1chc;,b#ijcahj;,in]t +r$i5t   
tol]ance exemption2 e4g41 a m>k] su* z  
,,npt ,,ii2 review$ 9                   
,,bppd4#ffc1haf;,b#ijdaha;,import       
tol]ance or tol]ance exemption2 process$
 commodities_/food only 7in]t or active 
+r$i5t74#iabg1fcj;,b#ijeahb 7new7,,sap  
,review4#ffc1haf;,b#ijfahc              
7new7,petition to e/abli% a tempor>y    
tol]ance_/tol]ance exemption = "o or m  
active +r$i5ts4#cca1ijg;,b#ijgahd       
7new7,petition to e/abli% a tempor>y    
tol]ance_/tol]ance exemption = "o or m  
active +r$i5ts bas$ on an exi/+ tempor>y
 tol]ance_/tol]ance                     
exemption4#cab1gfd;,b#ijhahe            
7new7,petition to e/abli% a tempor>y    
tol]ance_/tol]ance exemption = "o or m  

active +r$i5ts or in]t                  
+r$i5ts4#cdd1fga,,table #ah4 -- ,,in]t  
,,+r$i5tsepa ,no4,new ,,cr              
,no4,action,decision ,review ,"t        
7,mon?s77#a7 ,regi/ration ,s]vice ,fee  
777#a7 ,a decision review "t t w\ld     
o!rwise end on a ,saturday1 ,sunday1 or 
f$]al holiday1 w be ext5d$ to end on !  
next bus9ess day47#b7 ,if ano!r cov]$   
application is submitt$ t dep5ds ^u an  
application to approve an in]t +r$i5t1  
ea* application w be subject to its     
respective regi/ration s]vice fee4 ,!   
decision review "t l9e = bo? submissions
 w be ! longe/ ( ! associat$            
applications4 ,if ! application cov]s   
multiple +r$i5ts gr\p$ by ,,epa into "o 
*emical class1 a s+le regi/ration s]vice
 fee w be assess$ = approval ( ^?       
+r$i5ts47#c7 ,if ,,epa data rules are   
am5d$ to newly require cle>ance "u      
section #djh ( ! ,,ffdca = an +r$i5t (  
an antimicrobial product :]e su* +r$i5t 
0 n previ\sly subject to su* a cle>ance1
 !n review ( ! data = su* cle>ance ( su*

 product is n subject to a regi/ration  
s]vice fee = ! tol]ance action = two    
ye>s f ! effective date ( ! rule47#d7   
,any o!r cov]$ application t is         
associat$ ) & dep5d5t on ! ,,hsrb review
 w be subject to its sep>ate regi/ration
 s]vice fee4 ,! decision review times = 
! associat$ actions run concurr5tly1 b w
 end at ! date ( ! late/ review "t47#e7 
,any o!r cov]$ application t is         
associat$ ) & dep5d5t on ! ,,sap review 
w be subject to its sep>ate regi/ration 
s]vice fee4 ,! decision review "t = !   
associat$ action w be ext5d$ by !       
decision review "t = ! ,,sap review47#f7
 ,an application = a new end-use product
 us+ a s\rce ( active +r$i5t t 7a7 is n 
yet regi/]$ b 7b7 has an application    
p5d+ ) ! ,ag5cy = review1 w be consid]$ 
an application = a new product ) an     
unregi/]$ s\rce ( active +r$i5t47#g7    
,:]e ! action involves approval ( a new 
or am5d$ label1 on or be=e ! end date ( 
! decision review "t1 ! ,ag5cy %all     
provide to ! applicant a draft accept$  

label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  

to ! ,ag5cy47#h7 ,if a new saf5] is     
submitt$ 9 ! same package z a new active
 +r$i5t1 & t new active +r$i5t is       
det]m9$ to be r$uc$ risk1 !n ! saf5]    
w\ld get ! same r$uc$ timeframe z ! new 
active +r$i5t4,i#jjaahf;,approval ( new 
food use in]t +r$i5t4 7#b77c7ac #bg1jjj 
,i#jjbahg;,am5d curr5tly approv$ in]t   
+r$i5t tol]ance or exemption f tol]ance2
 new data4 7#b7aag1ejj;,i#jjcahh;,am5d  
curr5tly approv$ in]t +r$i5t tol]ance or
 exemption f tol]ance2 no new data4     
7#b7ic1cjh;,i#jjdahi;,approval ( new    
non-food use in]t +r$i5t4 7#b7 #f       
#aa1jbe ,i#jjeaij;,am5d curr5tly approv$
 non-food use in]t +r$i5t ) new use     
patt]n2 new data4                       
7#b7fe1eac;,i#jjfaia;,am5d curr5tly     
approv$ non-food use in]t +r$i5t ) new  
use patt]n2 no new data4                
7#b7cc1cjh;,i#jjgaib;,approval (        
sub/antially simil> non-food use in]t   
+r$i5ts :5 orig9al in]t is              
compositionally simil> ) simil> use     
patt]n4 7#b7da1fed ,i#jjhaic;,approval (

 new or am5d$ polym] in]t +r$i5t1 food  
use4 7#b7ec1gdi;,i#jjiaid;,approval (   
new or am5d$ polym] in]t +r$i5t1        
non-food use4 7#b7                      
#dc1jhg;,i#jajaie,petition to am5d a    
s+le tol]ance exemption descriptor1 or  
s+le non-food use descriptor1 to add    
#aj ,c,a,s,r,ns2 no new data4           
7#b7fa1fed;,i#jaaaif 7new7,approval (   
new food use saf5] ) tol]ance or        
exemption f tol]ance4                   
7#b77h7bdeig1fhc;,i#jabaig              
7new7,approval ( new non-food use saf5]4
 7#b77h7badae1bda;,i#jacaih             
7new7,approval ( additional food use =  
previ\sly approv$ saf5] ) tol]ance or   
exemption f tol]ance4                   
7#b7aefb1ige;,i#jadaii 7new7,approval ( 
additional non-food use = previ\sly     
approv$ saf5]4 7#b7aebe1afh;,i#jaebjj   
7new7,approval ( new g5]ic data =       
previ\sly approv$ food use saf5]4       
7#b7bdbfi1gbh;,i#jafbja 7new7,approval (
 am5dm5t7s7 to tol]ance & label =       
previ\sly approv$ saf5]4                

7#b7acee1ggf,,table #ai4 -- ,,ext]nal   
,,review ,,& ,,miscellane\s ,,actionsepa
 ,no4,new ,,cr ,no4,action,decision     
,review ,"t 7,mon?s77#a7 ,regi/ration   
,s]vice ,fee 777#a7 ,a decision review  
"t t w\ld o!rwise end on a ,saturday1   
,sunday1 or f$]al holiday1 w be ext5d$  
to end on ! next bus9ess day47#b7 ,if   
ano!r cov]$ application is submitt$ t   
dep5ds ^u an application to approve an  
in]t +r$i5t1 ea* application w be       
subject to its respective regi/ration   
s]vice fee4 ,! decision review "t l9e = 
bo? submissions w be ! longe/ ( !       
associat$ applications4 ,if !           
application cov]s multiple +r$i5ts gr\p$
 by ,,epa into "o *emical class1 a s+le 
regi/ration s]vice fee w be assess$ =   
approval ( ^? +r$i5ts47#c7 ,if ,,epa    
data rules are am5d$ to newly require   
cle>ance "u section #djh ( ! ,,ffdca =  
an +r$i5t ( an antimicrobial product :]e
 su* +r$i5t 0 n previ\sly subject to su*
 a cle>ance1 !n review ( ! data = su*   
cle>ance ( su* product is n subject to a

 regi/ration s]vice fee = ! tol]ance    
action = two ye>s f ! effective date ( !
 rule47#d7 ,any o!r cov]$ application t 
is associat$ ) & dep5d5t on ! ,,hsrb    
review w be subject to its sep>ate      
regi/ration s]vice fee4 ,! decision     
review times = ! associat$ actions run  
concurr5tly1 b w end at ! date ( ! late/
 review "t47#e7 ,any o!r cov]$          
application t is associat$ ) & dep5d5t  
on ! ,,sap review w be subject to its   
sep>ate regi/ration s]vice fee4 ,!      
decision review "t = ! associat$ action 
w be ext5d$ by ! decision review "t = ! 
,,sap review47#f7 ,an application = a   
new end-use product us+ a s\rce ( active
 +r$i5t t 7a7 is n yet regi/]$ b 7b7 has
 an application p5d+ ) ! ,ag5cy =       
review1 w be consid]$ an application = a
 new product ) an unregi/]$ s\rce (     
active +r$i5t47#g7 ,:]e ! action        
involves approval ( a new or am5d$      
label1 on or be=e ! end date ( !        
decision review "t1 ! ,ag5cy %all       
provide to ! applicant a draft accept$  

label1 includ+ any *anges made by !     
,ag5cy t diff] f ! applicant-submitt$   
label & relevant support+ data review$  
by ! ,ag5cy4 ,! applicant w notify !    
,ag5cy t ! applicant ei!r 7a7 agrees to 
all ( ! t]ms associat$ ) ! draft accept$
 label z am5d$ by ! ,ag5cy & reque/s t x
 be issu$ z ! accept$ f9al ,ag5cy-/amp$ 
label2 or 7b7 does n agree to "o or m ( 
! t]ms ( ! draft accept$ label z am5d$  
by ! ,ag5cy & reque/s additional "t to  
resolve ! diff]5ce7s72 or 7c7 )draws !  
application )\t prejudice = subsequ5t   
resubmission1 b =feits ! associat$      
regi/ration s]vice fee4 ,= cases        
describ$ 9 7b71 ! applicant %all h up to
 #cj cal5d> days to rea* agreem5t ) !   
,ag5cy on ! f9al t]ms ( ! ,ag5cy-accept$
 label4 ,if ! applicant agrees to all ( 
! t]ms ( ! accept$ label z 9 7a71       
includ+ ^u resolution ( diff]5ces 9 7b71
 ! ,ag5cy %all provide an accept$ f9al  
,ag5cy-/amp$ label to ! regi/rant )9 #b 
bus9ess days foll[+ ! regi/rant's writt5
 or electronic confirmation ( agreem5t  

to ! ,ag5cy47#h7 ,due to l[ fee & %ort  
"t frame ?is category is n eligible =   
small bus9ess waiv]s4 ,gold seal applies
 to "o regi/]$ product47#i7 ,?is        
category includes am5dm5ts ! sole       
purpose ( :i* is to add ,df,e 7or       
equival5t t]ms t d n use 8safe0 or      
d]ivatives ( 8safe07 logos to a label4  
,df,e is a volunt>y program4 ,a label   
be>+ a ,df,e logo is n consid]$ an      
,ag5cy endorsem5t because ! +r$i5ts 9 ! 
qualify+ product mu/ meet objective1    
sci5tific crit]ia e/abli%$ & widely     
publiciz$ by ,,epa4,m#jjabjb,/udy       
protocol requir+ ,human ,/udies ,review 
,bo>d review z def9$ 9 #dj ,,cfr ,"p #bf
 9 support ( an active +r$i5t4 7#d7i    
#g1ich ,m#jjbbjc;,complet$ /udy requir+ 
,human ,/udies ,review ,bo>d review z   
def9$ 9 #dj ,,cfr ,"p #bf 9 support ( an
 active +r$i5t4                         
7#d7ig1ich,m#jjcbjd;,ext]nal te*nical   
pe] review ( new active +r$i5t1 product1
 or am5dm5t 7e4g41 consultation )       
,,fifra ,sci5tific ,advisory ,panel7 =  

an action ) a decision timeframe ( less 
?an #ab mon?s4 ,applicant initiat$      
reque/ bas$ on a requirem5t ( !         
,adm9i/rator1 z def9$ by ,,fifra        
#be7;d71 9 support ( a novel active     
+r$i5t1 or unique use patt]n or         
application te*nology4 ,excludes ,,pip  
active +r$i5ts4                         
7#e7abfc1ide,m#jjdbje;,ext]nal te*nical 
pe] review ( new active +r$i5t1 product1
 or am5dm5t 7e4g41 consultation )       
,,fifra ,sci5tific ,advisory ,panel7 =  
an action ) a decision timeframe (      
great] ?an #ab mon?s4 ,applicant        
initiat$ reque/ bas$ on a requirem5t ( !
 ,adm9i/rator1 z def9$ by ,,fifra       
#be7;d71 9 support ( a novel active     
+r$i5t1 or unique use patt]n or         
application te*nology4 ,excludes ,,pip  
active +r$i5ts4 7#e7                    
#ahfc1ide,m#jjebjf,new ,product3        
,comb9ation1 ,conta9s a comb9ation (    
active +r$i5ts f a regi/]$ &_/or        
unregi/]$ s\rce2 conv5tional1           
antimicrobial &_/or biope/icide4        

,requires coord9ation ) o!r regulatory  
divisions to conduct review ( data1     
label &_/or v]ify ! validity ( exi/+    
data z cit$4 ,only exi/+ uses = ea*     
active +r$i5t 9 ! comb9ation product4   
7#f77g7ibb1jej,m#jjfbjg,reque/ = up to  
#e lett]s ( c]tification 7,gold ,seal7 =
 "o actively regi/]$ product 7excludes  
di/ributor products74                   
7#h7abgg,m#jjgbjh,reque/ to ext5d       
,exclusive ,use ( data z provid$ by     
,,fifra ,section                        
#c7;c77#a77;,f77ii74#abe1eac            
,m#jjhbji,reque/ to grant ,exclusive    
,use ( data z provid$ by ,,fifra        
,section #c7;c77#a77;,f77vi7 = a m9or   
use1 :5 a ,,fifra ,section #b7ll77#b7   
det]m9ation is requir$4#aea1fed,m#jjibaj
 7new7,non-,,fifra ,regulat$            
,det]m9ation3 ,applicant initiat$1 p]   
product4#db1cfc,m#jajbaa                
7new7,conditional rul+ on               
pre-application1 product sub/antial     
simil>ity4#db1cfc,m#jaabab 7new7,label  
am5dm5t to add ! ,df,e logo2 requires   

data review2 no o!r label *anges4       
7#i7dc1fdh  4  #g4 ,ext5sion ,not)/&+   
any o!r provision ( ?is ,act or am5dm5t 
made by ?is ,act1 any ref]5ce 9 ?is ,act
 or an am5dm5t made by ?is ,act to #bjbj
 %all be deem$ to be a ref]5ce to #bjbc4
  #h4 ,agricultural work] protection    
/&>d2 c]tification ( pe/icide           
applicators  7a7 ,9 g5]al ,except z     
provid$ 9 subsection 7b71 dur+ ! p]iod  
beg9n+ on ! date ( enactm5t ( ?is ,act &
 end+ n e>li] ?an ,octob] #a1 #bjba1 !  
,adm9i/rator ( ! ,environm5tal          
,protection ,ag5cy 7ref]r$ to 9 ?is     
section z ! ,adm9i/rator7-- 7#a7 %all   
c>ry out-- 7,a7 ! f9al rule ( !         
,adm9i/rator entitl$ ,pe/icides2        
,agricultural ,work] ,protection ,/&>d  
,revisions 7#hj ,f$4 ,reg4 #fgdif       
7,novemb] #b1 #bjae772 &  7,b7 ! f9al   
rule ( ! ,adm9i/rator entitl$           
,pe/icides2 ,c]tification ( ,pe/icide   
,applicators 7#hb ,f$4 ,reg4 #ieb       
7,janu>y #d1 #bjag772 &  7#b7 %all n    
revise or develop revisions to ! rules  

describ$ 9 subp>agraphs 7,a7 & 7,b7 (   
p>agraph 7#a74  7b7 ,exceptions ,prior  
to ,octob] #a1 #bjba1 ! ,adm9i/rator may
 propose1 & aft] a notice & public      
comm5t p]iod ( n less ?an #ij days1     
promulgate revisions to ! f9al rule     
describ$ 9 subsection 7a77#a77;,a7      
address+ application exclusion zones "u 
"p #agj ( title #dj1 ,code ( ,f$]al     
,regulations1 consi/5t ) ! ,f$]al       
,insecticide1 ,fungicide1 & ,rod5ticide 
,act 7#g ,u4,s4,c4 #acf et seq474  7c7  
,,gao report ,! ,comptroll] ,g5]al ( !  
,unit$ ,/ates %all-- 7#a7 conduct a /udy
 on ! use ( ! designat$ repres5tative1  
includ+ ! effect ( t use on !           
availability ( pe/icide application &   
haz>d in=mation & work] heal? & safety2 
&  7#b7 n lat] ?an ,octob] #a1 #bjba1   
make publically available a report      
describ+ ! /udy "u p>agraph 7#a71       
includ+ any recomm5dations to prev5t !  
misuse ( pe/icide application & haz>d   
in=mation1 if t misuse is id5tifi$4     
,secret>y