,,ii #aadth ,,congress #ast ,session ,s4 #bjfg ,,in ,,the ,,senate ,,of ,,the ,,united ,,states ,september #bb1 #bjae ,mr4 ,wicker 7for himself1 ,mrs4 ,capito1 ,mr4 ,king1 ,mr4 ,schatz1 ,ms4 ,ayotte1 ,ms4 ,collins1 and ,mr4 ,barrasso7 introduced the following bill2 which was read twice and referred to the ,committee on ,health1 ,education1 ,labor1 and ,pensions ,a ,,bill ,to establish ,,eureka ,prize ,competitions to accelerate discovery and development of disease-modifying1 preventive1 or curative treatments for ,alzheimer's disease and related dementia1 to encourage efforts to enhance detection and diagnosis of such diseases1 or to enhance the quality and efficiency of care of individuals with such diseases4 #a4 ,short title ,this ,act may be cited as the ,ensuring ,useful ,research ,expenditures is ,key for ,alzheimer's ,act or the ,,eureka ,act4 #b4 ,authorization of ,national ,alzheimer's and ,dementia ,research ,breakthrough ,prize ,competitions ,part ,b of title ,,iv of the ,public ,health ,service ,act 7#db ,u4,s4,c4 #bhd et seq47 is amended by adding at the end the following3 #dji,k4 ,national ,alzheimer's and ,dementia ,research ,breakthrough ,prize ,competitions 7a7 ,in general ,the ,director of ,,nih1 in consultation with the ,director of the ,national ,science ,foundation1 the ,director of the ,defense ,advanced ,research ,projects ,agency1 the ,commissioner of ,food and ,drugs1 the ,director of the ,intelligence ,advanced ,research ,projects ,activity1 and the heads of any other appropriate ,federal agencies that have experience in prize competitions1 shall establish prize competitions4 ,the competitions shall be designed to achieve high-priority breakthroughs to achieve the national goals of preventing and treating ,alzheimer's disease by #bjbe1 enhancing quality and efficiency of care for individuals with ,alzheimer's disease1 and expanding supports for individuals with ,alzheimer's disease and the family caregivers of such individuals4 7b7 ,,eureka prize competitions 7#a7 ,in general ,the ,director of ,,nih1 in consultation with the ,director of the ,national ,science ,foundation1 the ,director of the ,defense ,advanced ,research ,projects ,agency1 the ,commissioner of ,food and ,drugs1 the ,director of the ,intelligence ,advanced ,research ,projects ,activity1 and the heads of any other appropriate ,federal agencies that have experience in prize competitions1 and when appropriate1 in coordination with private organizations1 shall establish ,,eureka prize competitions to accelerate breakthroughs in the area of ,alzheimer's disease and dementia that lead to the attainment of critical milestones set forth in the competitions4 ,the competitions may be in any of the following areas3 7,a7 ,identification and validation of non-invasive biomarkers to inform therapeutic targeting4 7,b7 ,identification of scalable1 non-invasive means of early detection and diagnosis of ,alzheimer's disease4 7,c7 ,repurposing of a drug approved by the ,food and ,drug ,administration as a disease-modifying treatment for ,alzheimer's disease4 7,d7 ,innovations1 including technological or telemedicine1 to improve care of individuals with ,alzheimer's disease or dementia and to ease the burden of caregiving for such individuals1 including cost burdens4 7,e7 ,breakthroughs to overcome a significant scientific barrier to understanding the pathology of ,alzheimer's disease4 7,f7 ,other ,alzheimer's disease and dementia needs1 as appropriate and as determined by the ,advisory ,council described in subsection 7c74 7,g7 ,other areas1 as the ,director of ,,nih determines appropriate4 7#b7 ,publication ,the ,director of ,,nih shall publish each competition that is offered in the ,federal ,register1 including the specific award amounts offered1 applicable deadlines1 and other eligibility criteria4 7#c7 ,eligibility ,to be eligible to win a prize under this section1 an individual or private organization-- 7,a7 shall have registered to participate in the competition under any rules promulgated by the ,director of ,,nih under paragraph 7#b72 7,b7 shall have complied with all the requirements under this section2 7,c7 in the case of a private organization1 shall be incorporated in and maintain a primary place of business in the ,united ,states1 and in the case of an individual1 whether participating singly or in a group1 shall be a citizen or permanent resident of the ,united ,states1 unless the ,director of ,,nih waives such requirement with respect to an organization or individual2 and 7,d7 may not be a ,federal entity or ,federal employee acting within the scope of their employment4 7c7 ,advisory council ,not later than #a year after the date of enactment of the ,,eureka ,act1 the ,director of ,,nih shall convene an ,advisory ,council of nongovernmental experts in ,alzheimer's disease and dementia to devise development of ,,eureka prize competitions under subsection 7b74 ,the council shall be comprised of #h members1 including-- 7#a7 #b experts from private organizations with expertise in managing multi-faceted prize competitions2 7#b7 #b experts in ,alzheimer's disease and dementia biomedical research2 7#c7 #b experts in ,alzheimer's disease and dementia therapy development1 including individuals with expertise in designing and executing human clinical trials2 and 7#d7 #b individuals from the caregiver or patient advocacy community4 7d7 ,evaluation of submissions ,the ,director of ,,nih1 in consultation with the ,advisory ,council1 shall appoint a panel of judges1 from within or outside the ,national ,institutes of ,health1 including from the private sector1 to review and evaluate all submissions for ,,eureka competitions4 ,the judging panel shall forward recommendations to the ,director of ,,nih and the ,advisory ,council4 ,the ,director of ,,nih shall evaluate all submissions recommended by the judging panel and select submissions for which the prize shall be awarded4 ,in reviewing submissions and selecting awardees1 the ,director of ,,nih may seek technical assistance and expertise from other ,federal agencies or external sources1 as appropriate4 7e7 ,administering the competitions ,the ,director of ,,nih may enter into an agreement with a private organization to administer prize competitions1 subject to the provisions of this section4 7f7 ,applicability of other provisions ,subsections 7e71 7h71 7i71 and 7j7 of section #bd of the ,stevenson-,wydler ,technology ,innovation ,act of #aihj shall apply to this section4 ,in applying such subsection 7h7 to this section1 the reference to subsection 7g7 shall be deemed to be a reference to subsection 7b7 of this section4 ,paragraphs 7#b7 and 7#c7 of subsection 7k7 of section #bd of the ,stevenson-,wydler ,technology ,innovation ,act of #aihj shall apply to the appointment and functioning of the panel of judges described in subsection 7d74 7g7 ,exemption from ,,faca ,the ,federal ,advisory ,committee ,act 7#e ,u4,s4,c4 ,app47 shall not apply to the advisory council established under subsection 7c7 or the judging panel appointed under subsection 7d74 7h7 ,private organizations ,in this section1 the term private organizations means nongovernmental entities1 including nonprofit and for-profit entities4 7i7 ,funding 7#a7 ,in general ,support for a prize competition under this section1 including financial support for the design and administration of a prize competition or monetary contributions or gifts of property for a prize purse1 may consist of ,federal appropriated funds1 funds provided by private organizations1 and individuals4 ,the ,director of ,,nih may solicit and accept funds from other ,federal agencies1 from private organizations1 and individuals to support such prize competitions4 ,the ,director of ,,nih may not give any special consideration to any individual or private organization in return for a donation4 7#b7 ,authorization of appropriations ,to carry out this section1 there are authorized to be appropriated not more than #aj1jjj1jjj1 for each of fiscal years #bjag through #bjba4 ,any funds appropriated under this paragraph shall remain available until ,september #cj1 #bjbe4 7#c7 ,clarification ,any funds made available through this section shall supplement1 not supplant1 other funding made available for research on ,alzheimer's disease and related dementia4 4