,,an ,,account ,,of ,,the ,,late ,,improvements ,,in ,,galvanism1 ,,with ,a ,,series ,,of ,,curious ,,and ,,interesting ,,experiments ,,performed ,,before ,,the ,,commissioners ,,of ,,the ,,french ,,national ,,institute1 ,,and ,,repeated ,,lately ,,in ,,the ,,anatomical ,,theatres ,,of ,,london4 ,,by ,,john ,,aldini1 ,,professor ,,of ,,experimental ,,philosophy ,,in ,,the ,,university ,,of ,,bologna1 ,,member ,,of ,,the ,,medical ,,and ,,galvanic ,,societies ,,of ,,paris1 ,,of ,,the ,,medical ,,society ,,of ,,london1 ,,etc4 ,,to ,,which ,,is ,,added1 ,,an ,,appendix1 ,,containing ,,the ,,author',s ,,experiments ,,on ,,the ,,body ,,of ,a ,,malefactor ,,executed ,,at ,,newgate4 c4 c4 ,,illustrated ,,with ,,engravings4 ,illustration3 ,medallions ,,london3 ,,printed ,,for ,,cuthell ,,and ,,martin1 ,,middle-,,row1 ,,holborn1 ,,and ,j4 ,,murray1 ,,no4 #cb1 ,,fleet-,,street1 ,,by ,,wilks ,,and ,,taylor1 ,,chancery-,,lane4 #ahjc4 ,,editor',s ,,preface4 ,few discoveries in modern times have excited so much curiosity as that of ,galvanism4 ,ever since it was first made known by its celebrated ,author1 it has engaged the attention of the most eminent philosophers in ,europe2 and various researches have been undertaken to ascertain the principles on which it depends2 and the laws to which it is subject4 ,though some of its singular properties are fully established1 it must be allowed that the discovery is still in its infancy2 but enough of it is known to prove its importance1 and to induce philosophers to continue their researches1 which there is every reason to suppose may lead to some very curious results4 ,the experiments1 indeed1 which have already been made1 seem to indicate that it may open a new field in the healing art2 and it appears by a late report presented to the ,class of the ,exact ,sciences of the ,academy of ,turin1 that the medical application of it has been attended with the most beneficial effects in a case of confirmed hydrophobia4 ,while ,galvanism1 independently of other advantages1 holds out such hopes of utility in regard to objects so interesting to mankind2 a work containing a full account of the late improvements which have been made in it1 illustrated by a complete course of experiments1 cannot fail of being acceptable to the public in general1 and in particular to medical men1 to whose department1 in one point of view1 it more essentially belongs4 ,when ,professor ,aldini left this country1 the manuscript1 written in ,french1 together with two printed ,latin ,dissertations1 was put into the ,editor's hands1 in order that they might be prepared for the press4 ,a translation of these forms the principal part of the work3 and an ,appendix has been added1 containing the author's experiments on the body of a malefactor executed at ,newgate2 experiments of a similar kind on the bodies of three criminals decapitated at ,bologna2 and an experiment lately made at ,calais1 which seems to show that ,galvanism is susceptible of being conveyed to a very considerable distance through the water of the sea4 ,the ,editor thinks it necessary to observe1 that the principal experiments1 of which an account is given in this work1 are illustrated by proper engravings1 and that the title page is embellished with a representation of the gold medal presented to the ,author1 as a mark of their respect1 by the medical professors and pupils of ,guy's and ,st4 ,thomas's ,hospitals4 ,,london1 ,may #abth1 #ahjc4 ,,contents4 ,,part ,i4 ,,page ,,of ,,the ,,nature ,,and ,,general ,,properties ,,of ,,galvanism4 ,,proposition ,i4 ,muscular contractions are excited by the development of a fluid in the animal machine1 which is conducted from the nerves to the muscles without the concurrence or action of metals #c ,,prop4 ,,ii4 ,the ,galvanism excited1 in the preceding experiments1 is not owing to the communication nor to the transfusion of the general electricity1 but to an electricity peculiar to animals1 which acts a very distinguished part in the animal economy #f ,,prop4 ,,iii4 ,galvanism develops itself in a powerful manner1 independently of metals1 by means of the human animal machine #h ,,prop4 ,,iv4 ,muscular contractions can be excited1 under certain conditions1 without establishing a continued arc from the nerves to the muscles #aa ,,prop4 ,v4 ,the effects of ,galvanism1 in the preceding experiments1 do not depend on the action of any stimulant1 which occurs in performing the experiments1 and ought not to be confounded with the effects of that action #ab ,,prop4 ,,vi4 ,galvanism is excited in the animal machine without any intermediate body1 and merely by the application of the nerves to the muscles #ad ,,prop4 ,,vii4 ,the heterogeneity of metals contributes1 in a great degree1 to excite muscular contractions with more facility1 but is not absolutely necessary to their production #ai ,,prop4 ,,viii4 ,the ,leyden flask1 the ,voltaic pile1 and animal substances1 have the faculty of absorbing principles from the atmospheric air in an insulated plenum #ba ,,prop4 ,,ix4 ,flame prevents the action of the ,leyden flask1 as well as that of the pile1 and also muscular contractions #bg ,,prop4 ,x4 ,certain fluids1 applied to the whole surface of the pile1 or of animal parts1 do not prevent the action of ,galvanism #bi ,,prop4 ,,xi4 ,mere electrization1 by means of the common kinds of apparatus1 does not increase the action of ,galvanism #cb ,,prop4 ,,xii4 ,the ,galvanic action is increased by employing as part of the arc the apparatus of ,volta1 or the electrified ,leyden flask #cd ,,prop4 ,,xiii4 ,galvanism1 in animals and in the pile1 traverses large spaces with the same rapidity as the electric fluid #cf ,,prop4 ,,xiv4 ,the muscular contractions1 which1 according to the observations of ,galvani1 are produced by an electric atmosphere whether natural or artificial1 correspond entirely with those produced by the pile1 or by similar kinds of apparatus #cg ,,prop4 ,,xv4 ,opium1 cinchona1 and other stimulants of a similar kind1 which exercise a powerful action on the animal machine1 contribute also to excite the action of the pile #da ,,prop4 ,,xvi4 ,if the general relation between ,galvanism and electricity be examined1 such a correspondence will be found between them1 as tends to confirm the analogy already stated #dd ,,prop4 ,,xvii4 ,the hypothesis of an animal pile1 analogous to that formed artificially1 seems well calculated to explain the sensations and contractions in the animal machine #dg ,,part ,,the ,,second4 ,,on ,,the ,,influence ,,which ,,galvanism ,,has ,,on ,,the ,,vital ,,powers #ec ,,section ,i4 ,galvanism applied to various quadrupeds1 birds1 and other warm-blooded animals #ed ,,section ,,ii4 ,experiments made on human bodies after death #fg ,,part ,,the ,,third4 ,,on ,,the ,,power ,,of ,,galvanism ,,as ,,applied ,,to ,,medicine #ig ,,sect4 ,i4 ,advantages which the medical administration of ,galvanism has over that of common electricity #ii ,,sect4 ,,ii4 ,application of ,galvanism to the organs of hearing and of sight #aja ,,sect4 ,,iii4 ,application of ,galvanism in cases of asphyxia and drowning #aaj ,,sect4 ,,iv4 ,galvanism applied to the cure of melancholy madness #aac ,,sect4 ,v4 ,general reflections on the action and influence which ,galvanism1 considered in a medical point of view1 exercises on the animal conomy #abc ,,dissertation on animal electricity1 read in the ,institute of ,bologna in the year #agic #acc ,,second ,,dissertation on animal electricity1 read in the ,institute of ,bologna in the year #agid #aee ,conclusion #ahf ,,appendix #ahi ,no4 ,i4 ,an account of the experiments performed1 by ,j4 ,aldini1 on the body of a malefactor executed at ,newgate ,jan4 #ag1 #ahjc ib4 ,no4 ,,ii4 ,report presented to the ,class of the ,exact ,sciences of the ,academy of ,turin1 #aeth ,august #ahjb1 in regard to the ,galvanic experiments made by ,c4 ,,vassali-,,eandi1 ,,giulio1 and ,,rossi1 on the #ajth and #adth of the same month1 on the bodies of three men a short time after their decapitation4 ,by ,c4 ,,giulio #bjd ,no4 ,,iii4 ,account of an experiment made at ,calais1 on the transmission of ,galvanism through an arm of the sea #bag ,,an ,,account ,,of ,,the ,,late ,,improvements ,,in ,,galvanism4 ,a just tribute of applause has been bestowed on the celebrated ,professor ,volta for his late discovery2 and ,i have no desire to deprive him of any part of that honour to which he is so justly entitled2 but ,i am far from entertaining an idea that we ought1 on this account1 to neglect the first labours of ,galvani4 ,though these two philosophers pursued different routes1 they concurred to throw considerable light on the same points of science2 and the question now is1 to determine which of them deduced the most just consequences from the facts he observed2 and then to ascertain whether the facts established by ,galvani lead to the theory of ,volta1 or whether those discovered by ,volta are connected with the theory of ,galvani4 ,for my part1 ,i am of opinion that these two theories may serve in an eminent degree to illustrate each other4 ,last year ,professor ,volta announced to the public the action of the metallic pile4 ,i here propose to exhibit1 according to the principles of ,professor ,galvani1 the action of the animal pile4 ,such is the plan ,i have conceived in order to reconcile the systems of these two illustrious philosophers3 it forms the object of the present work1 which is divided into three parts4 ,in the first ,i shall exhibit the action of ,galvanism independently of metals1 and explain some of its general properties4 ,the second will contain experiments on the power of ,galvanism to excite the vital forces4 ,in the third ,i shall propose some useful applications of it to medicine1 and explain the principles on which the new medical administration of ,galvanism is founded4 ,to render the work as methodical as possible1 ,i have endeavoured to arrange the experiments in such a manner that they may serve as proofs to a series of general propositions1 which1 it is hoped1 will be of use to physiology and to the doctrine of the animal economy4 ,,part ,,the ,,first4 ,,of ,,the ,,nature ,,and ,,general ,,properties ,,of ,,galvanism4 ,,proposition ,i4 ,muscular contractions are excited by the development of a fluid in the animal machine1 which is conducted from the nerves to the muscles without the concurrence or action of metals4 ,,experiment ,i4 ,having provided the head of an ox1 recently killed1 ,i thrust a finger of one of my hands1 moistened with salt water1 into one of the ears 7,plate ,i4 fig4 #a471 at the same time that ,i held a prepared frog in the other hand1 in such a manner that its spinal marrow touched the upper part of the tongue4 ,when this arrangement was made1 strong convulsions were observed in the frog2 but on separating the arc all the contractions ceased4 ,this experiment will succeed still better if the arc be conveyed from the tongue of the ox to the spinal marrow of the frog4 ,this method was found to be exceedingly convenient for trying the effect of ,galvanism on several calves4 ,,experiment ,,ii4 ,having provided the trunk of a calf1 ,i conveyed the arc from the muscles of the abdomen to the spinal marrow of a frog1 prepared and arranged in the usual manner4 ,the frog seemed much affected1 and the contractions were exceedingly violent when the arc was composed of a chain of different persons1 united together by the hands moistened with salt water4 ,,experiment ,,iii4 ,i connected1 by means of one chain of moisture1 the heads of two or three calves1 and observed that by this combination the force of the ,galvanism was exerted with more energy3 a frog1 which was not affected by touching one head1 experienced violent contractions when applied to a series of several heads connected together4 ,,experiment ,,iv4 ,i think it proper here to mention a very curious observation which ,i made lately at ,paris1 in company with professor ,huzzard1 and in the presence of the ,commissioners of the ,national ,institute4 ,on applying the spinal marrow of a prepared frog to the cervical muscles of a horse's head1 separated from the body1 no muscular convulsions took place2 but if1 at the same time1 another person touched with his hand1 moistened by a solution of muriate of soda1 the spinal marrow of the horse1 convulsions were always produced in the frog1 though there was no communication between the persons1 except that formed by a floor on which they stood4 ,,proposition ,,ii4 ,the ,galvanism excited1 in the preceding experiments1 is not owing to the communication nor to the transfusion of the general electricity1 but to an electricity peculiar to animals1 which acts a very distinguished part in the animal economy4 ,,experiment ,i4 ,having placed the trunk of a calf 7,plate ,i4 fig4 #b47 on an insulated table1 ,i made a longitudinal incision in the breast1 in order to obtain a long series of muscles uncovered4 ,i then arranged two insulated persons in such a manner that the one with a finger1 moistened by salt water1 touched the spinal marrow of the calf1 while the other applied the spinal marrow of a frog to the muscles of the trunk4 ,every time this arc was formed1 muscular contractions were produced in the frog4 ,when the two persons let go each other's hands1 the contractions ceased4 ,i repeated this experiment1 with the same success1 on the insulated head of an ox1 conveying the arc from the spinal marrow of the frog to the tongue4 ,frogs were as violently affected when the experiment was made with the insulated trunks of different kinds of birds4 ,this experiment1 in my opinion1 affords a decisive proof that the ,galvanic fluid is peculiar to the animal machine1 independently of the influence of metals1 or of any other foreign cause4 ,in these experiments1 indeed1 we have some animal machines1 so combined that the result is strong contractions in the frog4 ,all the bodies were insulated2 and1 therefore1 it cannot be supposed that the contractions were occasioned by the direct influence of that general principle1 which pervades every body in nature4 ,hence it is evident1 whether it be ascribed to the action of the animal chain1 formed by the arms of the persons1 or to the animal pile1 formed by the trunk of the calf1 that we shall still be obliged to acknowledge the action of a principle which belongs to the organization of the animal machine1 without having any dependence on metals4 99 99 99 99 99 ,to prove in the animal body the existence of a principle which philosophers can by certain means excite and direct at pleasure in their experiments1 is a matter of the greatest importance2 though the manner in which it is put in action by nature1 however wonderful1 is unknown to us4 ,here then we have developed a very energetic fluid1 capable of transmission1 and deriving its origin from the action of the animal forces2 since the parts of bodies separated from the common reservoir of general electricity have still of themselves the faculty of reproducing it1 and of causing it to circulate in a manner proper for exciting muscular contractions4 ,,proposition ,,iii4 ,galvanism develops itself in a powerful manner1 independently of metals1 by means of the human animal machine4 ,,experiment ,i4 ,if you hold in your hand1 moistened with salt water1 the muscles of a prepared frog1 and apply the crural nerves to the tip of your tongue1 you will immediately see violent contractions produced in the frog4 ,all suspicion of any stimulant exerting an action in this case1 may be removed by repeating the experiment with the frog held in the dry hand3 the muscular contractions will then cease1 unless the action of ,galvanism in the frog1 or in the animal machine1 be uncommonly powerful2 in which case contractions may be produced without establishing an arc from the nerves to the muscles4 ,,experiment ,,ii4 ,i held the muscles of a prepared frog in one of my hands1 moistened by salt water1 and brought a finger of the other hand1 well moistened1 near to the crural nerves4 ,when the frog possessed a great deal of vitality the crural nerves gradually approached my hand1 and strong contractions took place at the point of contact4 ,this experiment proves the existence of a very remarkable kind of attraction1 observed not only by myself1 but also by those whom ,i requested to repeat the experiment4 ,,experiment ,,iii4 ,the above experiment requires great precision in the preparation1 and a considerable degree of vital power in the frog4 ,i have been informed by ,professor ,fontana1 in a letter lately received from him1 that this phnomenon depends on very delicate circumstances1 which he proposes to explain4 ,he assures me1 at the same time1 that he has twice seen the nerve attracted1 in this manner1 by the muscle4 ,being desirous to render this phnomenon more evident1 ,i formed the arc1 by applying one of my hands to the spinal marrow of a warm-blooded animal1 while ,i held a frog in the other1 in such a manner that the crural nerves were brought very near to the abdominal muscles4 ,by this arrangement the attraction of the nerves of the frog became very sensible4 ,i performed this experiment for the first time1 at ,oxford1 before ,sir ,christopher ,pegge and ,dr4 ,bancroft1 and repeated it in the anatomical theatres of ,st4 ,thomas's and ,guy's hospitals4 ,,experiment ,,iv4 ,i made the same observations on the body of a man as ,i had before made on the head and trunk of an ox4 ,having obtained the body of an executed criminal1 ,i formed an arc from the spinal marrow to the muscles1 a prepared frog being placed between1 and always obtained strong contractions without the aid of the pile1 and without the least influence from metals4 ,i obtained the same result1 in a certain degree1 from the bodies of men who had died a natural death4 ,,experiment ,v4 ,let four or more persons hold each other by the hands1 moistened by a solution of muriate of soda1 so as to form a long animal chain4 ,if the first hold in his hand the muscles of a prepared frog2 and if the last1 at the other end of the chain1 touch the spinal marrow or the crural nerves1 contractions will be produced3 if the animal chain be broken1 the contractions will immediately cease4 ,i performed this experiment1 making the animal chain to consist of two persons1 before the ,galvanic ,society at ,paris1 and in ,mr4 ,wilson's anatomical theatre1 ,windmill-street4 ,,proposition ,,iv4 ,muscular contractions can be excited1 under certain conditions1 without establishing a continued arc from the nerves to the muscles4 ,,experiment4 ,having obtained the body of an executed criminal1 ,i caused the biceps muscle to be laid bare1 and brought near to it the spinal marrow of a prepared frog4 ,by these means contractions were produced in it much stronger than ,i had ever obtained in warm-blooded animals4 ,i repeated the experiment1 being myself insulated1 and observed no signs of contraction4 ,the same phnomena were exhibited with the head of an ox1 which possessed an extraordinary degree of vitality4 ,,proposition ,v4 ,the effects of ,galvanism1 in the preceding experiments1 do not depend on the action of any stimulant1 which occurs in performing the experiments1 and ought not to be confounded with the effects of that action4 ,,experiment ,i4 ,in the experiment of the frog applied to the uncovered biceps muscle of the body of the malefactor1 if any other body be made to touch the frog it will remain motionless4 ,this proves that the contractions produced in the frog do not arise from the impulse of the mere contact of the spinal marrow with the muscle of the human animal machine4 ,,experiment ,,ii4 ,to remove still further all suspicion of the action of stimulants1 in the preceding experiments1 ,i prepared two frogs1 and connected the extremities of one with the spinal marrow of the other4 ,i then held in my hand the extremities of one of the frogs1 and applied the spinal marrow of the other to the uncovered muscles of the head of an ox1 which possessed a great degree of vitality4 ,by these means contractions were produced in both the frogs4 ,it is evident1 in this experiment1 that the force of the stimulant1 if there were any1 might act on the second frog1 but not on the first4 ,,proposition ,,vi4 ,galvanism is excited in the animal machine without any intermediate body1 and merely by the application of the nerves to the muscles4 ,several philosophers have endeavoured to obtain this interesting result4 ,professor ,volta1 in a letter which he addressed to me1 in ,brugnatelli's ,journal1 observed1 8that various parts of animals can excite ,galvanism1 independently of metals40 ,galvani1 a short time before his death1 proposed two ingenious methods of obtaining this result1 and gave me a description of them4 ,this1 however1 has not been able to destroy the incredulity of some philosophers1 who hitherto have confounded ,galvanism with metallic electricity1 under an idea that all contractions proceed from irritation1 produced by the action of metals4 ,for this reason ,i have1 with confidence1 announced my method1 which enables any one to observe this important result4 ,,experiment ,i4 ,having prepared a frog in the usual manner1 ,i hold the spinal marrow in one hand 7,plate ,i4 fig4 #c471 and with the other form an angle with the leg and foot1 in such a manner that the muscles of the leg touch the crural nerves4 ,on this contact strong contractions1 forming a real electrico-animal alarum 7carillon71 which continue longer or shorter according to the degree of vitality1 are produced in the extremity left to itself4 ,in this experiment1 as well as in the following1 it is necessary that the frogs should be strong and full of vitality1 and that the muscles should not be overcharged with blood4 ,,experiment ,,ii4 ,by observing the directions already given1 very strong convulsions will be obtained2 but they must not be ascribed to the impulse produced by bringing the nerve into contact with the muscle4 ,if the experiment be repeated1 covering the muscle1 at the place of contact1 with a non-conducting substance1 the contractions will entirely cease2 but they will be re-produced as soon as the nerve is made to touch the muscular substance4 ,in performing this experiment1 in public1 ,i obtained several times more than two hundred successive contractions2 but this was never the case when ,i formed the same contact with the muscle by means of a conducting substance1 and even with a plate of metal4 ,to ensure the success of this interesting experiment1 the nerves must be prepared as speedily as possible1 by disengaging them from every foreign substance4 ,it will be proper also to apply the nerves not to one but to several points of the muscle1 throughout its whole length4 ,it is observed1 that the contact of the nerves with the tendinous parts which communicate with the muscles1 often serves to increase the muscular contractions4 ,i performed the above experiment before several able professors1 among whom were the celebrated ,brugnatelli and ,carcano1 who1 with that modesty peculiar to them1 made several ingenious observations on the precision which might be given to it4 ,professor ,brugnatelli was apprehensive that1 as ,i had accidentally touched some metals before ,i performed the experiment1 metallic particles might have adhered to my fingers1 and thus have served1 in some measure1 as invisible arming1 sufficient of itself to excite muscular contractions4 ,this suspicion1 however1 ,i removed1 by immersing my hands in water1 to detach every foreign substance4 ,he then observed that animal moisture1 independently of the circulation of the ,galvanic fluid from the nerves to the muscles1 might also excite muscular contractions2 and he requested that the crural nerves might be washed in common water4 ,this was accordingly done2 and the humidity of the nerves being thus externally removed1 very strong contractions were still produced1 as the professor found1 to his full conviction1 on repeating the experiment himself several times#a4 #a ,it may not be improper here to observe1 that my method of exciting muscular contractions1 without metals1 is very different from that proposed by others4 ,i do not know that convulsions have ever been obtained in cold-blooded animals by means of warm-blooded4 ,from observations ,i have made1 ,i flatter myself with the hope of being able to obtain contractions without metals1 even in the muscles of warm-blooded-animals4 ,but to ensure the certainty of this method would require long practice1 and a preparation attended with considerable difficulty4 ,i however propose to attempt it on my return to ,italy4 ,some philosophers1 indeed1 had conceived the idea of producing contractions in a frog without metals2 and ingenious methods proposed by my uncle ,galvani induced me to pay attention to the subject1 in order that ,i might attain to greater simplicity4 ,he made me sensible of the importance of the experiment1 and therefore ,i was long ago inspired with a desire of discovering that interesting process4 ,it will be seen in the ,opuscoli of ,milan1 that ,i shewed publicly1 to the ,institute of ,bologna1 contractions in a frog without the aid of metals1 so far back as the year #agid4 ,the experiment1 as described in a memoir addressed to ,m4 ,amorotti1 is as follows3 8,i immersed a prepared frog in a strong solution of muriate of soda4 ,i then took it from the solution1 and1 holding one extremity of it in my hand1 ,i suffered the other to hang freely down4 ,while in this situation1 ,i raised up the nerves with a small glass rod1 in such a manner that they did not touch the muscles4 ,i then suddenly removed the glass rod1 and every time that the spinal marrow and nerves touched the muscular parts1 contractions were excited4 ,any idea of a stimulus arising either from the action of the salt1 or from the impulse produced by the fall of the nerves1 may be easily removed4 ,nothing will be necessary but to apply the same nerves to the muscles of another prepared frog1 not in a ,galvanic circle2 for1 in this case1 neither the salt1 nor the impulse even if more violent1 will produce muscular motion4 ,,experiment ,,iii4 ,the ,commissioners of the ,french ,national ,institute remarked1 that1 in order to give the greatest precision possible to these experiments1 it would be necessary to insulate entirely the nervous and muscular systems4 ,for this purpose1 ,i applied these parts to each other by means of glass rods1 and each time they were brought into contact ,i obtained muscular contractions4 ,the case was the same when an animal arc was applied to two insulated frogs3 contractions were produced in them both4 ,the apparatus employed for this purpose may be seen in ,plate ,i4 fig4 #e and #f4 ,,experiment ,,iv4 ,having prepared a frog according to the usual method1 ,i cut one of its crural nerves in such a manner that the trunk was united to the spinal marrow by means of the other nerve1 which remained uncut1 and also by a blood-vessel contiguous and parallel to the cut nerve4 ,i then repeated the above experiment2 and1 though only one nerve was in contact with the muscles1 ,i obtained the same results4 ,,experiment ,v4 ,a ligature was placed loosely around the middle of the crural nerves1 and one of these nerves at the ligature applied to the corresponding muscles3 strong contractions ensued2 which1 however1 did not take place1 when the ligature was drawn tight1 at the insertion of the nerves into the muscles of the thigh4 ,,proposition ,,vii4 ,the heterogeneity of metals contributes1 in a great degree1 to excite muscular contractions with more facility1 but is not absolutely necessary to their production4 ,this proposition ,i could demonstrate in a direct manner1 by means of experiments1 which ,i published formerly1 on the contractions excited by very pure mercury1 and which were repeated1 in different ways1 by the celebrated ,humboldt4 ,i am1 however1 happy to have an opportunity of examining the influence of arming with heterogeneous substances2 and ,i shall endeavour to prove that it cannot1 of itself1 produce the effect of muscular contractions4 ,,experiment ,i4 ,if several prepared frogs1 ten or more for example1 be placed on a table 7,plate ,i4 fig4 #g471 and arranged parallel to each other1 in such a manner that the whole system of the nerves shall be at one end1 and that of the muscles at the other1--on applying two armatures and a metallic arc to the first of these frogs1 muscular convulsions will be immediately excited1 not only in the first frog1 but in all the rest4 ,,experiment ,,ii4 ,if the experiment be repeated with the frogs arranged in such a manner that the spinal marrow and muscles are not each at one end 7,plate ,i4 fig4 #h471 but disposed alternately so that the spinal marrow of one touches sometimes the muscles of another1 or vice versa1 convulsions will then be produced only in some of the frogs1 and not in the whole series4 ,this experiment proves that the effect does not1 in any manner1 depend on the action of metals2 because metallic electricity in the first experiment ought to exercise an action only on the first frog1 and not on the rest2 and1 in the second1 ought to cause them all to move together1 or to leave them motionless4 ,i shall now proceed to those experiments which appear to be best calculated to support the opinion of the great analogy between electricity and ,galvanism4 ,,proposition ,,viii4 ,the ,leyden flask1 the ,voltaic pile1 and animal substances1 have the faculty of absorbing principles from the atmospheric air in an insulated plenum4 ,,experiment ,i4 ,by means of a metallic point1 ,i electrified the interior side of a glass jar1 which ,i inverted and placed on a plate of metal1 so as to form an insulated plenum4 ,in a little time1 ,i saw the water rise in the glass several lines2 and ,i then flattered myself with the hopes of obtaining some remarkable effects by another method4 ,,experiment ,,ii4 ,i provided for this experiment a ,leyden flask1 seven inches in height and about three in diameter1 coated in the usual manner with tin foil3 the exterior end of the wire terminated in a sharp point1 so that the electric fluid which escaped from it could easily combine with the principles of the atmospheric air1 with which it had a greater affinity4 ,i then electrified the jar1 and covered it with a glass receiver of such a size that its electricity could not be weakened by the sides of the latter4 ,i thus formed an insulated plenum1 and at the end of half an hour ,i saw the water ascend in the receiver in a very sensible manner4 ,,experiment ,,iii4 ,having made the wire to terminate1 not in a point1 but in a metallic knob1 as usual1 ,i again charged the jar1 and having placed it under a common receiver1 at the end of about half an hour ,i found that the elevation of the water was much greater4 ,to remove every suspicion that this might arise from the water employed in the preceding experiment1 to insulate the plenum1 ,i substituted mercury in its stead2 and though the elevations were less1 they were1 however1 analogous to those which had been observed a little before with water4 ,by repeating this experiment with a similar jar1 not electrified1 one may be easily convinced1 that the elevation of the water in the bell ought not to be ascribed to a difference in the temperature of the air within it4 ,,experiment ,,iv4 ,i placed under a bell-glass1 forming an insulated plenum1 a pile consisting of fifty plates of silver and zinc4 ,next morning ,i observed that the water had risen some inches1 indicating that a great absorption of air had taken place4 ,having then introduced a taper into the receiver1 it was immediately extinguished4 ,the pile1 without being arranged anew1 was placed under the same receiver2 and on forming an insulated plenum1 ,i observed1 after twenty-four hours had elapsed1 a sensible absorption of air4 ,a taper was then introduced1 and ,i obtained the same result4 ,i replaced the pile under the receiver1 and found1 on the third and following days1 that the pile retained its moisture1 so that till the tenth day it gave analogous results4 ,i repeated the same experiment with oxygen gas1 and found1 six days after1 that the water in the bell had risen a foot4 ,,experiment ,v4 ,the same results may be obtained without employing large piles and large receivers4 ,in general1 it will be sufficient to arrange1 in alternate strata1 some plates of heterogeneous metals4 ,if two plates of copper and zinc be placed under a bell an inch and a half in diameter1 and three inches in height1 and if an insulated plenum be then formed1 two days after the water will have risen about half an inch4 ,having repeated the experiment with different metals1 ,i found that a greater or less absorption of air had taken place1 according to the difference of their nature and combination4 ,this inspired me with the idea of making a series of experiments with different metals2 and ,i hope to be able1 at some future period1 to form a table of the different heights of the fluid1 which may serve to determine how far they are respectively susceptible of oxidation4 ,however1 to ascertain the oxidation of metals with precision1 pieces of coin mixed with alloy ought not to be employed4 ,pure metals1 formed into small piles1 must be subjected to observation1 and ought to be placed under equal bells1 at the same temperature as that of the atmosphere4 ,until it be proved that the absorption of oxygen in the above experiments is merely a chemical effect1 altogether unconnected with the action of ,galvanism1 ,i think ,i may be allowed to avail myself of it to prove the proposed analogy4 ,,experiment ,,vi4 ,the ingenious theory of ,girtanner1 who ascribes the cause of muscular contractions to oxygen1 the curious experiments by which ,professor ,humboldt revives the muscular force1 by means of oxygenated muriatic acid1 and those made by the celebrated ,fourcroy on the same subject1 induced me to examine the effect resulting from a combination of oxygen with muscular fibres1 in a state of the greatest vitality4 ,for this purpose1 ,i adapted to a bell-glass a bent metallic wire1 from which were suspended fourteen frogs1 prepared with the utmost dispatch1 and almost at the same instant1 by myself and several of my pupils2 and having formed an insulated plenum1 ,i found1 at the end of twenty-four hours1 that the water had risen in the bell to the height of about half an inch4 ,,experiment ,,vii4 ,i repeated this experiment1 with the same success1 on warm-blooded animals4 ,i provided1 for that purpose1 the extremities of different pullets from which the crural nerves had been previously separated1 and found that the elevations of the water1 in the insulated plenum1 were much less when ,i employed the fibres of these animals after their vitality had been weakened4 ,,experiment ,,viii4 ,having obtained the bodies of some executed criminals1 ,i exposed to the action of an insulated plenum the nervous and muscular fibres1 and the substance of the brain4 ,the elevations of the water were remarkable1 in consequence of the different substances subjected to experiment1 which1 according to their different characters1 exercised a different action on the oxygen4 ,this fact ought to induce physiologists to undertake experiments of a similar kind with other gases1 to enable them to determine the strength of the affinity exerted by animal substances to combine with oxygen4 ,,experiment ,,ix4 ,as fishes1 and in particular the torpedo1 furnish a large quantity of animal or ,galvanic electricity1 ,i was inclined to think they would exhibit the before-mentioned effects in a very striking manner in an insulated plenum4 ,i mentioned to ,professor ,mojon of ,genoa the experiment ,i proposed to make2 and1 in a letter which ,i lately received from him1 he informed me of the result1 as follows3 8,i took a strong torpedo1 and1 as soon as it was dead1 armed its nerves with the usual armature4 ,having then placed it on an insulating stool1 a little elevated above water1 ,i covered it with a bell-glass the content of which was equal to #dcb cubic inches4 ,at the end of some hours ,i observed1 with great surprise1 that the water under the insulated plenum began to rise progressively during about ten hours2 and at the end of forty-eight ,i found that it had risen an inch2 so that it occupied a ninth part of the capacity of the bell1 that is to say1 forty-eight cubic inches4 ,i analysed the remaining air1 and found that the bell contained no more than #hj cubic inches of oxygen gas1 and #cbd of azotic gas2 and that1 during the above period1 more than two-fifths of the oxygen gas contained in the bell had been absorbed40 ,i propose going to the sea-coast1 in order that ,i may repeat the experiment on the torpedo without any armature2 and ,i shall embrace that opportunity of making various researches in regard to the new theory of ,galvanism4 ,i think it necessary1 in general1 to submit to new experiments the different animal parts immersed in the different ariform fluids1 fixing their various combinations according to the degrees of ,galvanic force which they may possess4 ,,proposition ,,ix4 ,flame prevents the action of the ,leyden flask1 as well as that of the pile1 and also muscular contractions4 ,,experiment ,i4 ,i placed a lighted taper on an insulating stool2 and having made the wire1 proceeding from the interior coating of a charged ,leyden flask1 to pass through the flame1 ,i found that1 without forming an arc1 it lost a portion of its electricity4 ,if the experiment be repeated in such a manner that the flame makes a part of the arc between the two coatings1 the flask is entirely discharged1 without the arms of the person who forms part of the arc experiencing the least shock4 ,,experiment ,,ii4 ,i adapted to the summit of the pile a circular brass vessel1 containing spirit of wine4 ,by these means the pile was made to terminate in a strong flame1 to which ,i applied a metallic conductor1 while with the other hand ,i touched the bottom of the pile4 ,the ,galvanic fluid still withstood my efforts2 and the case was the same when ,i substituted for the spirit of wine the flame of a common candle4 ,it is proper here to remark1 that the flame did not lessen the action of the ,galvanism when the conductor1 instead of being applied to the flame1 was applied to the plate at the summit of the pile4 ,,experiment ,,iii4 ,i have already proved by a series of experiments1 addressed to ,c4 ,lacepede1 that flame made to form part of the arc applied to the nerves and muscles of a frog1 prevents muscular contractions4 ,i repeated the experiment1 with the same result1 on several warm-blooded animals4 ,i observed that the flame interposed in the arc1 which touched the back and belly of the torpedo1 prevented the electric shocks4 ,,proposition ,x4 ,certain fluids1 applied to the whole surface of the pile1 or of animal parts1 do not prevent the action of ,galvanism4 ,,experiment ,i4 ,two years ago1 ,i made various experiments on this subject at ,florence1 with the celebrated ,fontana2 and we found that a pile1 composed of a hundred plates of zinc and silver1 after being immersed some time in common water1 still exercised a very strong action4 ,professor ,fontana informs me1 in a letter1 that he has performed the same experiment several ways1 and always with the same success4 ,,experiment ,,ii4 ,being desirous to examine the nature of the element inhabited by the numerous family of fishes1 which are also subject to the influence of the ,galvanic processes1 ,i filled with sea-water thirty earthen vessels2 and having formed a communication between them1 by means of heterogeneous arcs1 composed of brass and zinc1 ,i obtained a shock1 which appeared to me stronger than that obtained with artificial salt water4 ,by establishing an arc with only five of these vessels1 the action was very sensible4 ,a pile composed of pieces of pasteboard1 moistened with sea-water1 and entirely immersed in the same water1 gave1 when tried1 very strong shocks4 ,,experiment ,,iii4 ,i was able to prove the action of the ,galvanic pile and of metals under water1 by the following simple experiment3 ,i placed a plate of zinc at the bottom of a vessel filled with salt water1 7,plate ,,ii4 fig4 #f474 ,a person then brought the spinal marrow of a frog into contact with the surface of the salt water2 and another person1 absolutely insulated1 touched with a silvered copper wire the plate of zinc4 ,every time that the wire was brought into contact with the zinc1 muscular contractions took place4 ,i am well aware1 that the advocates for metallic electricity will deduce from the plain statement of this fact1 an induction contrary to ,galvanism2 but my candour1 on this occasion1 will show how much ,i am attached to the cause of truth4 ,,experiment ,,iv4 ,among animal bodies1 the torpedo is one of those which produce the most powerful ,galvanic action4 ,in the autumn of #ahja1 ,i made some experiments on this animal at ,genoa1 in conjunction with ,professor ,mojon and his brother1 who gave me every assistance in their power4 ,when ,i touched the torpedo1 under water1 at the moment when it gave the shock1 it contracted itself1 and two jets of water proceeded from the two holes in its head4 ,to obtain the shock1 it was not necessary to touch two distinct parts of its body3 in many cases1 the application of the hand to the electric organ was sufficient4 ,,proposition ,,xi4 ,mere electrization1 by means of the common kinds of apparatus1 does not increase the action of ,galvanism4 ,,experiment ,i4 ,artificial electricity was communicated to an apparatus1 composed of a hundred cups1 care being first taken to insulate the table and the persons who were afterwards to receive the action of it4 ,if we suppose that the heterogeneous arcs were charged with different kinds of electricity1 it would seem that1 by communicating to them any electricity1 the electricity of the whole apparatus ought to have been reduced to the same kind2 consequently that no shock ought to have been produced4 ,the contrary1 however1 was the case4 ,we experienced very strong shocks1 very little different from those which would have been obtained without artificial electricity4 ,i observed the same result with the pile4 ,,experiment ,,ii4 ,an insulated torpedo being electrified1 the shocks it gave were not increased4 ,the torpedo was killed1 and then armed1 according to the method of ,galvani1 for the purpose of trying whether metallic electricity1 in this case1 would have any influence over it4 ,after this arrangement was made1 every time that the conducting arc was applied to it strong contractions were produced2 but very little different from those remarked in other animals4 ,this observation is agreeable to those made at ,naples by the celebrated ,abilgaard1 who1 having subjected the torpedo to the ,galvanic processes1 found no extraordinary contractions4 ,,proposition ,,xii4 ,the ,galvanic action is increased by employing as part of the arc the apparatus of ,volta1 or the electrified ,leyden flask4 ,,experiment ,i4 ,in the hall of the ,institute1 ,i placed on a large table a hundred glass cups1 and arranged them in such a manner as to form two rectangles1 each composed of fifty4 ,i established a communication between the first of these cups and the apparatus of ,volta1 by means of a metallic wire1 which proceeded from one of the interior chambers of the ,cabinet de ,physique1 and terminated at the place where the experiment was performed4 ,i then tried this arrangement several times2 and1 however different opinions might be in regard to the precise increase of the action of the ,galvanism1 all constantly agreed in considering the shock as stronger4 ,some even went so far as to assert that it was increased a third4 ,it gave me great satisfaction to be able1 on this occasion1 to confirm the last discovery of ,professor ,volta1 as well as one of those which he had made before4 ,one observation1 well attested1 which tends to establish the truth of this proposition1 is1 that if a person touch the summit and base of the pile with two large metallic conductors1 the shocks he receives will be much stronger4 ,,experiment ,,ii4 ,electricity1 concentrated in the ,leyden flask1 contributes also to increase the action of ,galvanism4 ,having prepared a pile1 composed of fifty plates of copper and zinc1 ,i formed an arc by interposing a charged jar1 and obtained an explosion much stronger than that obtained by the ,leyden flask charged with an equal quantity of the electric fluid1 and discharged independently of the pile4 ,,experiment ,,iii4 ,i took the same flask1 after it was discharged1 and having formed a portion of an arc1 applied to the two extremities of the pile1 ,i observed that the ,galvanism refused to pass the obstacle presented to it by the stratum of glass interposed between the two coatings2 consequently ,i received no shock4 ,,experiment ,,iv4 ,i repeated the second experiment1 insulating the pile1 and at the same time the person who touched the pile with the charged flask4 ,by these means ,i obtained a much stronger explosion than could have been produced separately by the ,leyden flask or the pile4 ,in this experiment ,i observed that the repeated passage of the electricity of the flask throughout the whole extent of the pile1 did not deprive it of the property of exciting ,galvanism4 ,,proposition ,,xiii4 ,galvanism1 in animals and in the pile1 traverses large spaces with the same rapidity as the electric fluid4 ,,experiment4 ,i extended an iron wire1 two hundred and fifty feet in length1 around my chamber1 taking great care that it should not any where touch itself1 and made its extremities to terminate at a table which ,i had prepared for the experiment4 ,one of these extremities being brought into communication with a pile composed of fifty plates of copper and zinc1 ,i held the other in my left hand1 and with my right touched the summit of the pile4 ,the ,galvanism then proceeded from the bottom of the pile to the summit1 traversing a portion of the arc formed by the animal machine4 ,by the effect of this passage1 we may therefore form some opinion of the celerity of the ,galvanic current4 ,its rapidity was such1 that neither ,i nor any of those who repeated the experiment publicly1 were able to determine the degree4 ,the truth of this proposition is confirmed by experiments lately made by the celebrated ,van ,marum1 who charged large batteries by means of ,galvanism4 ,,proposition ,,xiv4 ,the muscular contractions1 which1 according to the observations of ,galvani1 are produced by an electric atmosphere whether natural or artificial1 correspond entirely with those produced by the pile1 or by similar kinds of apparatus4 ,when a change of equilibrium takes place in those systems of bodies which communicate with the nerves and the muscles of the animal machine1 it is always sensible of this change1 and muscular contractions are produced4 ,,experiment ,i4 ,it is curious to see an animal1 placed at the extremity of an apartment1 experience a shock1 when the electric spark is extracted at a considerable distance4 ,i performed this experiment several times in the ,cabinet de ,physique of the ,institute of ,bologna1 by means of a metal wire1 not insulated1 which was at the distance of four feet from the conductor of a common electrical machine4 ,i repeated the experiment with crural nerves1 having a ligature in the middle2 and on extracting the spark1 ,i observed violent contractions1 which ceased when the ligature was formed at the place of their insertion into the muscles4 ,i then performed with the new apparatus of ,volta the experiments which ,galvani had made with artificial electricity alone4 ,at first ,i employed several glass cups and piles of from one to two hundred plates of metal2 which proved to me that similar results might be obtained with the following simple apparatus4 ,,experiment ,,ii4 ,having placed upon a table two glass vessels filled with salt water1 7,plate ,,ii4 fig4 #e47 which ,i connected by means of an arc composed of brass and zinc1 ,i applied to the surface of the water1 in one of the vessels1 the spinal marrow of a prepared frog1 the corresponding muscles of which ,i held in one of my hands4 ,another person with his hand1 or a plate of metal1 then touched the water contained in the other vessel1 and1 at each contact1 the muscles experienced violent contractions4 ,to remove all idea of the contractions being produced by the action of the salt water1 ,i connected with the spinal marrow a part of the muscles of another animal1 which1 instead of the spinal marrow1 was made to touch the salt water1 and obtained the same result4 ,,experiment ,,iii4 ,the same apparatus being retained1 if either the person who touches the surface of the water in the first glass vessel1 or the part of the frog immersed in the second1 be insulated1 no muscular contractions are produced2 but they again take place when the insulation is removed4 ,the violence of the contractions is increased by increasing the number of the glass vessels4 ,if these vessels are made to communicate by means of arcs1 formed of one homogeneous metal1 the results are not different from those observed when heterogeneous metals are employed4 ,,experiment ,,iv4 ,being desirous to confirm the theory of the ,galvanic atmosphere1 ,i placed in it the body of an executed criminal4 ,i removed the pile to the distance of a foot from the trunk1 without the usual communication of metallic arcs2 and having made an incision in each ancle1 two persons held two frogs prepared in the usual manner1 in such a position that the spinal marrow rested on the incisions4 ,when matters were thus arranged1 every time that a third person touched the summit of the pile1 both the frogs experienced violent contractions1 and to such a degree1 that1 leaving free one of the extremities1 a real electrico-animal alarum was obtained1 perfectly similar in its effect and identity to that described by ,galvani in his ,commentary4 ,when the metallic apparatus is employed1 if one of the persons who holds a frog be insulated1 the frog will remain motionless1 while the other will experience the usual effect4 ,i had an opportunity of confirming the truth of this observation1 on the trunk of a dog1 during a course of experiments made in the ,hpital de la ,charit1 at ,paris1 and at ,st4 ,thomas's ,hospital1 ,london4 ,,proposition ,,xv4 ,opium1 cinchona1 and other stimulants of a similar kind1 which exercise a powerful action on the animal machine1 contribute also to excite the action of the pile4 ,,experiment ,i4 ,in the last sitting of the ,institute of ,bologna1 at which ,i was present1 ,i constructed two piles1 each composed of fifteen pieces of silver and zinc1 employing for the one an extract of opium1 and for the other an infusion of cinchona in alcohol4 ,i covered the piles with two equal receivers2 formed an insulated plenum1 by pouring mercury around the bottoms of them2 and placed weights on the receivers sufficient to prevent the mercury from raising them4 ,at the end of some hours1 ,i found a remarkable elevation of the surface of the mercury1 so that the receivers remained fixed without requiring any weight to keep them down4 ,in the bell which covered the pile where extract of opium had been employed1 the mercury rose more than an inch2 but in that covering the other1 where cinchona had been used1 the elevation of the mercury was scarcely three lines4 ,,experiment ,,ii4 ,having successively introduced a taper into each of the two receivers before mentioned1 it was immediately extinguished in that containing the pile with the extract of opium2 but in the other containing the pile with the infusion of cinchona1 it continued burning for some time4 ,i found also that four of the plates1 at the bottom of the pile where ,i employed opium1 had suffered from the action of the mercury2 and that some others1 to the height of about three inches and a half1 exhibited a few globules of that metal4 ,the pile in which ,i employed infusion of cinchona showed scarcely any signs of the action of the mercury4 ,,experiment ,,iii4 ,as ,i concluded that the pile in which ,i had employed the alcoholic extract of opium possessed more activity than the other1 ,i examined it for four or five days successively4 ,i tried the flame of a taper with the same result as before1 and assured myself that this pile retained the ,galvanic power1 though a little weakened1 even till the eighth day4 ,on the other hand1 twenty-four hours had scarcely elapsed1 when the pile in which alcohol and cinchona had been employed exhibited no signs of activity4 ,,experiment ,,iv4 ,i constructed two piles1 in the same manner1 with pieces of pasteboard interposed1 which had been previously moistened with strong solutions of camphor and of castor oil1 in pure alcohol4 ,in these two piles the ,galvanic effects were much weaker in every respect than those observed in the preceding experiment2 for1 besides the explosion being less1 the elevation of water in the insulated plenum was very small1 and the alteration of the flame was scarcely sensible4 ,,experiment ,v4 ,i was able to convince myself that the effects of the two piles1 before mentioned1 were the immediate result of the substances dissolved1 and not of the alcohol2 for1 having constructed a pile of thirty plates of silver and zinc1 with pieces of pasteboard interposed1 moistened with pure alcohol1 ,i observed no signs of ,galvanism2 and the case was the same when ,i employed a pile of zinc combined with copper and other metals4 ,,proposition ,,xvi4 ,if the general relation between ,galvanism and electricity be examined1 such a correspondence will be found between them1 as tends to confirm the analogy already stated4 ,to illustrate this proposition1 ,i shall here take a view of the particular properties of electricity and ,galvanism1 which1 if considered separately1 would not be sufficient for my object4 ,i am1 however1 of opinion1 that when combined together they will serve to prove it in a satisfactory manner4 #ast1 ,galvanism1 like artificial electricity1 emits sparks1 fuses metals1 and can even be employed to charge armed non-conducting bodies4 ,i have proved the last-mentioned property1 discovered by the celebrated ,van ,marum1 with a new apparatus1 composed of a pile with a hole in the middle1 in which ,i place the flask ,i intend to charge4 #b;dly1 ,the influence of artificial electricity tends to accelerate the putrefaction of animal parts2 and the same phnomenon may be produced by communication with the ,voltaic pile1 or by the first processes of ,galvani4 #c;dly1 ,the electricity of the ,leyden jar is renewed in part immediately after its discharge4 ,a similar phnomenon is exhibited by the pile2 and it is observed1 if the common ,galvanic armatures be employed1 that the vital force in animals is almost revived1 when the arcs are applied different times4 #dthly1 ,as the action of common electricity and of the pile is suspended1 when the combination of the metallic pieces is changed2 in like manner1 in a system of several animal machines1 if their combination be changed1 muscular contractions entirely cease4 #ethly1 ,water may be decomposed by common electricity1 as well as by the ,galvanic pile1 according to the ingenious method proposed by ,dr4 ,wollaston4 ,i lately saw1 with the greatest pleasure1 experiments on this subject performed by himself with the utmost neatness and precision4 ,it is much to be wished1 that the same result could be obtained by animal ,galvanism alone2 as it might tend to throw great light on some important points in physiology4 ,for my part1 ,i entertain no doubt that1 after repeated trials1 it may one day be effected1 by means of large animals possessing a great abundance of animal electricity4 ,to conclude3 ,i think ,i may venture to assert1 that the correspondence between the properties of ,galvanism and common electricity might be carried to a much greater extent1 in confirmation of the analogy which ,i proposed to prove in this proposition4 ,,proposition ,,xvii4 ,the hypothesis of an animal pile1 analogous to that formed artificially1 seems well calculated to explain the sensations and contractions in the animal machine4 ,it seems to be proved by the observations of ,mr4 ,davy1 ,professor in the ,royal ,institution of ,great ,britain1 and those of ,m4 ,gautherot at ,paris1 that a pile may be composed without any metallic substances whatever4 ,we are therefore naturally led to suppose1 that one may be composed also of animal substances alone4 ,though this has never yet been obtained by art1 we behold it with admiration constructed by nature in various animals4 ,if we examine1 indeed1 the structure of the regular bodies which succeed each other in the torpedo1 the electrical eel of ,surinam1 and in the silurus1 we shall find them to be real animal piles1 differently arranged3 and if an animal pile1 exceedingly strong1 be capable of communicating a shock1 why should not one of a more moderate nature excite that activity which is necessary to produce muscular convulsions8 ,i have already proved1 that the system of the nerves and that of the muscles possess different ,galvanic powers1 or1 as it were1 different kinds of electricity1 to which the animal moisture serves as a conductor4 ,in this point of view1 the discovery of the pile of the celebrated ,volta1 instead of destroying the principle of ,galvanism1 tends rather in a powerful manner to support it4 ,the object of ,galvani's system is to prove the existence of an animal electricity1 and then to explain how its action operates in producing muscular sensations and contractions4 ,the first part of his system rests upon facts1 the truth of which neither time1 nor the different experiments made by philosophers1 have been able to weaken4 ,the second presents an hypothesis which1 perhaps1 may be further illustrated when the physiology of the human body is better known4 ,galvani1 to explain the activity of animal electricity1 supposes the nerves and muscles to be like the ,leyden jar2 and this idea ,i confidently adopted4 ,but by the expression #8,leyden flask' he meant nothing else than that in the animal machine there are two opposite kinds of electricity1 resulting from the nervous and the muscular systems1 to which animal moisture continually serves as a vehicle4 ,it was in this sense that he announced his theory of the ,leyden flask1 in his public lectures1 and in his last works4 ,no better comparison was then known1 in the language of philosophy1 to express this action4 ,it however affords me great pleasure1 that ,i can now substitute for it the pile discovered by ,volta1 which is perfectly consistent with the system of ,galvani2 and since ,i am ready to allow that the invention of the metallic pile gives ,volta a title to the discovery of metallic electricity1 ,i hope the discovery of animal electricity1 properly so called1 will be allowed to ,galvani1 as similar phnomena are exhibited by the nervous and muscular systems1 independently of common electricity4 ,but some important questions in regard to ,galvanism still remain to be answered1 such as the following3 whether the action of chemical combinations be the cause of ,galvanism1 or whether ,galvanism be the cause of chemical combinations4 ,in my opinion1 we have not yet a sufficient number of data to determine this point4 ,it may also be asked1 whether ,galvanism be of the same nature as electricity1 but differently modified by the animal organization4 ,for my part1 until their identity be proved by further researches1 ,i shall be contented with admitting that there is a great analogy between them4 ,but leaving these questions1 the discussion of which might be premature1 it will be better to deduce general corollaries from the series of experiments already detailed4 ,,corollary ,i4 ,it is found that there is a real attraction between certain parts of animals2 and this tends to confirm the idea of a sort of atmosphere peculiar to parts of animals1 as has been suggested by ,humboldt4 ,by these means it will perhaps be one day possible to explain1 with less difficulty1 the correspondence of some sensations in the animal machine4 ,,corollary ,,ii4 ,the action of ,galvanism on the ariform fluids may serve to explain its influence over the animal fluids by the oxidation of the humours1 and other phnomena which hitherto have been explained only in a hypothetical manner4 ,,corollary ,,iii4 ,fishes1 and several amphibious animals which live under water1 sometimes approach the surface on certain changes of the atmosphere4 ,when the before-mentioned experiments on the ,galvanic atmosphere are considered1 we may easily explain1 why those changes which take place in distant parts of the atmosphere are communicated to the element in which these animals reside4 ,,corollary ,,iv4 ,it has been ascertained1 that water saturated with salts1 and in particular with muriate of soda1 contributes a great deal to increase the effects of ,galvanism4 ,it is well known also1 that fishes1 as compared with other animals1 possess a very high degree of vitality2 and hence we have reason to admire the wisdom of nature in making the sea1 which is destined for the abode of fishes1 to be abundantly saturated with muriate of soda4 ,,corollary ,v4 ,as ,galvanism possesses great activity in chemical decompositions1 it cannot remain in a state of inaction2 but must necessarily produce great changes in the animal fluids and functions4 ,,corollary ,,vi4 ,this principle1 to which some of the grand operations of nature have been entrusted1 is not hypothetical2 since it has been proved1 that as there is a metallic arc and a metallic pile in the mineral kingdom1 there is also an animal arc and an animal circle in the animal kingdom2 which may one day throw great light on the progress of medicine1 and be productive of considerable benefit to the human race4 ,,part ,,the ,,second4 ,,on ,,the ,,influence ,,which ,,galvanism ,,has ,,on ,,the ,,vital ,,powers4 ,to conduct an energetic fluid to the general seat of all impressions2 to distribute its influence to the different parts of the nervous and muscular systems2 to continue1 revive1 and1 if ,i may be allowed the expression1 to command the vital powers2 such are the objects of my researches1 and such the advantages which ,i purpose to derive from the action of ,galvanism4 ,the discovery of the ,galvanic pile by the celebrated ,volta has served as a guide to enable me to obtain the most interesting results2 and to these ,i have been conducted by numerous researches and a long series of experiments4 ,i have examined the whole range of nature1 and the grand family of animals has afforded me the means of making observations1 highly interesting to physiology1 on the whole conomy of the vital powers4 ,my experiments on this subject ,i shall divide into two ,sections4 ,,section ,i4 ,galvanism applied to various quadrupeds1 birds1 and other warm-blooded animals4 ,,experiment ,i4 ,the head of an ox1 recently killed1 was subjected to the action of a pile 7,plate ,,ii4 fig4 #a47 composed of fifty plates of copper and zinc1 separated1 as usual1 by small pieces of pasteboard moistened with a solution of muriate of soda4 ,having moistened one of the ears with the same solution1 by means of a syringe1 ,i introduced into it one extremity of a metallic wire4 ,i then formed an arc with this wire to the summit of the pile1 and by means of another wire made a communication between the bottom of the pile and the nostrils4 ,when this apparatus was applied1 the eyes were seen to open1 the ears to shake1 the tongue to be agitated1 and the nostrils to swell1 in the same manner as those of the living animal1 when irritated and desirous of combating another of the same species4 ,i then moistened both the ears with salt water1 by the same method as before1 and inserted into each an extremity of one of the arcs4 ,when the ,galvanism was communicated1 the movements already described were reproduced2 but they appeared to be much more violent4 ,,experiment ,,ii4 ,a pile composed of a hundred pieces of silver and zinc 7,plate ,,ii4 fig4 #b47 being employed1 the tongue issued from the mouth four inches1 and re-entered it an inch1 on each application of the arc2 notwithstanding the resistance opposed by the teeth which pressed against it3 so that after four or five applications of the arc it was entirely restored to its usual situation4 ,i repeated this curious experiment several times at ,bologna and ,turin1 and lately at ,london before their ,royal ,highnesses the ,prince of ,wales1 the ,duke of ,york1 the ,duke of ,clarence1 and the ,duke of ,cumberland1 who seemed to be much interested in my researches4 ,i showed them that the tongue returned without being touched1 merely by forming an arc between distant parts1 such as the spinal marrow and the cervical or nasal muscles4 ,a person who held the extremity of the tongue with a pair of pincers felt the effort it made to return every time that the ,galvanism was applied4 ,,experiment ,,iii4 ,with the same apparatus ,i suspended from the extremity of the conducting arc the posterior half of a frog1 by bending the iron wire at right angles into a small elbow2 and then1 instead of making the tongue touch the extremity of the arc1 ,i brought it into contact with one of the paws of the frog1 while the other extremity of the wire rested on the summit of the pile4 ,when this arrangement was made1 ,i not only obtained the same contractions in the head of the ox1 but ,i observed also that when the paw of the frog ceased to be in contact with the tongue1 it was attracted by the latter1 which produced in it oscillations1 so that it formed a kind of ,galvanometer2 for the thighs of the small animal diverged more or less according to the intensity of the fluid which passed through them1 and were restored to their former position when the paw of the frog and the tongue of the ox were again brought into contact4 ,these oscillations continued about six minutes4 ,suspecting1 however1 that the crural nerves might have some share in these phnomena1 independently of the pile1 ,i cut these nerves1 and under similar conditions ,i obtained the same results4 ,,experiment ,,iv4 ,being desirous to repeat the above experiments on the heads of other oxen1 and on those of sheep and lambs1 varying the pile1 both in regard to its nature and the number of pieces1 ,i constructed three piles of twenty-five1 fifty1 and a hundred and twenty pieces of silver and zinc4 ,the results1 however1 differed from the preceding only in the greater or less intensity of the contractions1 according as one or the other apparatus was applied to the same animals4 ,i remarked in particular1 that the combination most favourable to muscular contractions is obtained1 when the arc is established from the ears to the spinal marrow4 ,in this case the eye is so much affected1 that the eye-lids open entirely while the eye-ball turns round1 and projects somewhat from its socket1 as sometimes happens in the most violent madness4 ,,experiment ,v4 ,having provided an ox recently killed1 the head of which was not cut off1 ,i formed an arc from one ear to the other1 interposing the pile4 ,the immediate result was a commotion so violent in all the extremities of the animal1 that several of the spectators were much alarmed1 and thought it prudent to retire to some distance4 ,i then cut off the head1 and formed an arc from the spinal marrow1 first to the diaphragm1 and then to the sphincter ani4 ,in the first case1 the diaphragm experienced violent contractions2 in the other ,i obtained a very strong action on the rectum1 which even produced an expulsion of the fces4 ,,experiment ,,vi4 ,to give more extent to my experiments1 ,i thought proper to repeat them on lambs1 chickens1 and other warm-blooded animals2 and without enumerating such phnomena as are common1 ,i shall only observe1 that the tongue1 which was projected beyond the lips1 again returned into the cavity of the mouth1 after several applications of the arc1 as was the case in the second experiment4 ,the movements of the ears and eye-lids were stronger than in the other parts4 ,comparative anatomy must explain why this phnomenon1 so striking in animals of this kind1 is not observed in man4 ,,experiment ,,vii4 ,the observations which ,i had made on the ,galvanism of the pile excited my curiosity so much1 that ,i was induced to try some comparative experiments by means of common electricity4 ,with this view ,i placed an iron wire in each ear of a lamb1 and discharged through it twice in succession a ,leyden flask1 the two coatings of which were in communication with the wires applied to the ears4 ,by these means ,i obtained contractions1 but weaker than those produced by the pile2 and ,i always observed the same result in other warm-blooded animals4 ,,experiment ,,viii4 ,having repeated the same experiments on live chickens1 ,i found1 to my great surprise1 notwithstanding the weakness of their organization1 that they sustained with firmness the strongest shocks1 communicated several times1 with a pile composed of fifty plates of silver and zinc4 ,though apparently dejected1 and almost on the point of expiring1--as soon as ,i interrupted the action of the pile1 they fluttered their wings1 and seemed to congratulate themselves on their escape from danger4 ,the curiosity natural to a philosopher induced me to subject these birds to anatomical dissection1 that ,i might examine what effects had been produced on the animal machine by these convulsions4 ,the principal phnomena which ,i observed were extravasated blood in the muscles2 a derangement of the humours in different parts2 the intestines removed from their usual seat1 and thrown towards the pelvis4 ,at some future period1 ,i purpose to examine how long these animals are capable of living under the continued action of ,galvanism1 applied to them in different ways4 ,,experiment ,,ix4 ,i applied the ,galvanic action to a pullet just killed1 forming an arc from one of the ears to the other4 ,when this arrangement was made1 ,i observed contractions not only in the feet1 but also in the wings and the whole animal machine4 ,the same phnomena were produced by the same means in two other pullets4 ,i then combined the different parts of these three pullets in such a manner1 that the head of the second was joined to the foot of the first1 and the head of the third to the head of the second4 ,an arc being then formed to the two extremities of this chain of animal parts1 ,i was much pleased to see the three pullets move their wings and their feet at the same time4 ,,experiment ,x4 ,the results of the preceding experiments led me to examine the power of an arc formed by animal moisture4 ,for this purpose1 having connected the heads of two oxen1 7,plate ,,ii4 fig4 #c47 by bringing near each other the sections of the neck1 ,i established an arc from the summit of the pile to one of the ears of one head1 and another from the base of the pile to one of the ears of the other4 ,when this arrangement was made1 ,i observed that both the heads exhibited evident signs of muscular contractions4 ,,experiment ,,xi4 ,the trunks of two calves being united by the sections of the neck1 and an arc being established by the interposition of the pile from the anus of the one to that of the other1 both the trunks received1 at the same time1 a commotion1 but not very violent4 ,i repeated this experiment on the trunks of two lambs1 but with a more striking result1 as all the extremities and muscles experienced violent convulsions4 ,a glass vessel1 employed for the experiments1 which stood on the table1 was overturned by one of the extremities1 and thrown to the distance of about two feet4 ,i tried other combinations1 but the contractions were weaker4 ,,experiment ,,xii4 ,having sawn open the skull1 ,i directed the action of the pile to different parts of the brain1 in the same order as they occurred in the course of anatomical dissection4 ,all these parts appeared to be affected by the ,galvanic force2 but its action was stronger on the corpus callosum and the cerebellum4 ,the same result nearly was obtained1 when ,i repeated the experiment on the heads of different calves and lambs4 ,,experiment ,,xiii4 ,the heart of an ox1 removed from the body1 being exposed to the action of ,galvanism1 though the pile was very powerful1 exhibited no signs of muscular contraction4 ,i repeated the same experiment on the heart of an ox1 without removing it from the body1 and on the hearts of several dogs1 one arc being applied to the spinal marrow1 while the other touched sometimes the surface of the heart1 and sometimes penetrated into its substance2 but with the same result3 no muscular convulsions were produced4 ,,experiment ,,xiv4 ,i prepared some frogs2 and having waited till the motion of the ventricles of the heart had become very slow1 and almost imperceptible1 ,i communicated to them the ,galvanic influence1 and it appeared to me that some movements were produced in the ventricles4 ,i repeated this experiment lately on the heart of a rabbit1 and with the same success4 ,having tried the hearts of several calves and dogs1 ,i could not observe any decided motion in the ventricles2 but ,i remarked that the ,galvanic power exercised a strong action on the auricles4 ,,experiment ,,xv4 ,without taking into consideration the differences in the action of ,galvanism on the heart1 according to the different applications and the different kinds of animals subjected to experiment1 ,i observed1 that after this muscle has lost its susceptibility to the action of ,galvanism1 the other muscles still retain it in a very high degree4 ,this effect is very striking in regard to the heart and the muscles of oxen and dogs2 and this corresponds with what has been stated by the ,commissioners of the ,french ,national ,institute in their ,report4 ,speaking of the anomalies found in this respect in the heart1 they conclude that it is at any rate certain that this organ loses1 in a very short time1 and much sooner than the other muscles1 the faculty of being agitated by ,galvanism4 ,,experiment ,,xvi4 ,all the observations ,i was able to make on the involuntary muscles will be found in the same ,report1 from which the following is an extract3 8,dr4 ,grapengiesser says1 that he saw the vermicular motion of the intestines increased by the action of ,galvanism in a living subject1 whose large intestines protruded beyond the abdomen1 in consequence of a scrotal hernia4 ,professor ,aldini made us observe the same effect on the intestinal canal of a dog4 ,we perceived also very evident contractions in a portion of the stomach1 separated from the animal4 ,we saw the auricles of the heart contract2 but never found this to be the case with the ventricles40 ,,experiment ,,xvii4 ,as ,i found it difficult1 in the course of my travels1 to obtain large animals for my experiments1 a desire of prosecuting my researches induced me to be satisfied with such small animals as were easiest to be procured4 ,i therefore declared war against the dogs1 which exhibited the same phnomena as oxen1 and with the greatest energy1 as may be seen by the following extract from the before-mentioned ,report of the ,commissioners of the ,french ,national ,institute3 8,the head of a dog being cut off1 ,aldini subjected it to the action of a strong pile1 by which means the most frightful convulsions were produced4 ,the mouth opened1 the teeth gnashed1 the eyes rolled in their orbits2 and1 if the imagination had not been restrained by reason and reflection1 one might have almost believed that the animal was restored to life1 and in a state of agony40 ,,experiment ,,xviii4 ,the head and trunk of a dog1 separated from each other1 and placed in such a manner as to leave an interval of about a foot between them 7,plate ,,ii4 fig4 #d471 were made to move simultaneously by applying the ,galvanic action to one of the ears1 and to a small incision made in one of the extremities of the trunk4 ,i saw the same effect produced in a public sitting held at the ,hpital de la ,charit at ,paris4 ,in this case1 the distance between the head and trunk was a foot and a half4 ,,experiment ,,xix4 ,in the preceding experiments1 it is always necessary that the part of the table which forms the interval between the head and trunk should be moistened with salt water1 or some other conducting fluid4 ,considered in this point of view1 the head and trunk mutually form an arc which conducts the ,galvanic action2 so that the contractions excited at the same time do not depend on the particular organization of the animals subjected to experiment4 ,this ,i confirmed by producing simultaneous contractions in the trunk of a dog combined with the head of a rabbit1 and vice versa4 ,,experiment ,,xx4 ,at the ,school of ,medicine at ,paris1 in presence of the ,commissioners of the ,french ,national ,institute1 and of ,professor ,huzzard1 ,i tried the action of ,galvanism on a horse which had been killed by the insufflation of air into the jugular veins4 ,the trunk exhibited no extraordinary motion2 but the head was violently agitated4 ,a very sensible gnashing of the teeth was produced1 and all the muscles performed1 in a surprising manner1 the same motion as is exerted during the time of mastication4 ,there was even a visible excretion of the saliva4 ,of all the heads hitherto tried1 that of the horse exhibited the most violent motion by the action of ,galvanism4 ,,experiment ,,xxi4 ,having performed this series of experiments1 it was necessary that a comparison should be made1 cteris paribus1 between the action of those stimulants proposed by the celebrated ,haller1 and the means here used to excite the action of ,galvanism4 ,for this purpose ,i employed a head weakened to such a degree that it was no longer sensible to the action of the ,hallerian stimulants applied to the muscles and nerves1 and then to different parts of the brain laid bare1 and separated one from the other4 ,i tried the action of the sulphuric and nitric acids1 and the effect of the bistouri1 but without ever producing the smallest contraction in warm-blooded animals3 on the other hand1 the action of ,galvanism1 on these parts1 in the above state1 occasioned very powerful muscular contractions4 ,,section ,,ii4 ,experiments made on human bodies after death4 ,from the experiments already described1 one might by analogy conjecture what effect the action of ,galvanism would produce on that noble being man1 the sole object of my researches4 ,but to enable philosophers to judge with more certainty respecting the effects of this wonderful agent1 it was necessary to adhere to certain conditions1 and to apply it immediately after death4 ,the bodies of persons who had died of disease were not proper for my purpose2 because it is to be presumed1 that the development of the principle which occasions death destroys the elasticity of the fibres1 and that the humours are changed from their natural to a corrupted state4 ,it was therefore necessary to obtain the human body while it still retained1 after death1 the vital powers in the highest degree of preservation2 and hence ,i was obliged1 if ,i may be allowed the expression1 to place myself under the scaffold1 near the axe of justice1 to receive the yet bleeding bodies of unfortunate criminals1 the only subjects proper for my experiments4 ,in consequence of an application made for that purpose1 ,i obtained from ,government the bodies of two brigands1 who were decapitated at ,bologna in the month of ,january #ahjb4 ,as both these individuals had been very young1 and of a robust constitution1 and as the parts exhibited the utmost soundness1 ,i entertained strong hopes of obtaining the happiest results from my proposed researches4 ,though accustomed to a more tranquil kind of operations in my closet1 and little acquainted with anatomical dissections1 the love of truth1 and a desire to throw some light on the system of ,galvanism1 overcame all my repugnance1 and ,i proceeded to the following experiments4 ,,experiment ,,xxii4 ,the first of these decapitated criminals being conveyed to the apartment provided for my experiments1 in the neighbourhood of the place of execution1 the head was first subjected to the ,galvanic action4 ,for this purpose ,i had constructed a pile consisting of a hundred pieces of silver and zinc4 ,having moistened the inside of the ears with salt water1 ,i formed an arc with two metallic wires1 which1 proceeding from the two ears1 were applied1 one to the summit and the other to the bottom of the pile4 ,when this communication was established1 ,i observed strong contractions in all the muscles of the face1 which were contorted in so irregular a manner that they exhibited the appearance of the most horrid grimaces4 ,the action of the eye-lids was exceedingly striking1 though less sensible in the human head than in that of the ox4 ,,experiment ,,xxiii4 ,having established an arc from the top of the left ear1 and then from the bottom of that ear to the tongue1 drawn about an inch without the mouth1 contractions were observed in the face1 and the tongue sensibly returned into the mouth4 ,i then touched the upper or lower lips1 and obtained contractions1 which were remarkable chiefly in all the muscles of the left part of the face2 so that the mouth appeared as if distorted by a partial kind of palsy4 ,on the first application of the arc1 a small quantity of saliva was discharged from the mouth4 ,,experiment ,,xxiv4 ,i caused the head to be shaved exactly above the parietal protuberance on the right side2 and having moistened the integuments1 armed with silver and zinc1 ,i established a communication by means of the pile between the parietal bone and one of the ears4 ,i obtained contractions1 but weaker than those observed when the arcs were formed according to the different methods already described4 ,,experiment ,,xxv4 ,having formed an arc from the ears to different parts of the face1 moistened with a solution of muriate of soda1 such for example as the nose and forehead1 ,i always observed violent contractions4 ,but the contractions were stronger when1 instead of the first-mentioned pile1 ,i employed another consisting of fifty plates of copper and zinc4 ,i even still decreased the number of plates1 in order that ,i might try1 in the course of these experiments1 the different degrees of activity which the pile would exhibit4 ,,experiment ,,xxvi4 ,the head of the other criminal being brought to me after ,i had employed about half an hour in these experiments1 ,i repeated them on this second head1 and found the results to be analogous to those before obtained4 ,but the contractions produced in the second head were stronger in consequence of its greater vitality3 the vitality of the first seemed to have been nearly exhausted4 ,,experiment ,,xxvii4 ,being desirous to examine1 according to the principles of ,galvani1 the power of an arc of animal moisture in warm-blooded animals1 ,i recollected that ,i had several times observed simultaneous convulsions produced by these means in two frogs1 and recently in the heads of two oxen1 the arc being conveyed from the one to the other in different ways4 ,i placed the two heads in a straight line on a table1 in such a manner that the sections of the neck were brought into communication merely by the animal fluids4 ,when thus arranged1 ,i formed an arc from the pile to the right ear of one head1 and to the left ear of the other1 and saw with astonishment the two heads make horrid grimaces2 so that the spectators1 who had no suspicion of such a result1 were actually frightened4 ,it was however observed1 that the convulsions excited in the heads disposed in this manner1 were not so strong as those produced when ,i performed the experiment on each head separately4 ,it is certain that1 in this experiment1 the arc of animal moisture supplies the place of a continuation of the nervous and muscular fibres4 ,,experiment ,,xxviii4 ,having tried the effect of ,galvanism on the exterior part of the head1 ,i proceeded to examine the phnomena exhibited by the interior organs when treated in the same manner4 ,i therefore removed the upper part of the cranium by a section parallel to its base1 uncovered the pia mater1 and established an arc from one of the ears to the medullary substance4 ,on the application of the arc strong convulsions were observed in the face4 ,while preparing the brain for my experiments1 ,i remarked that1 in dividing the muscles of the forehead1 at each stroke of the dissecting knife1 very strong contractions1 which continued after the dissection was finished1 were excited in the muscles of the face4 ,i was informed that this is an uncommon phnomenon in anatomical dissections2 and therefore ,i shall leave it to anatomists to determine whether it was occasioned1 either in whole or in part1 by the preceding action of the pile4 ,,experiment ,,xxix4 ,having then separated the lobes of the brain1 ,i applied the arc to the corpus callosum1 to the ears or to the lips1 and found that the whole osseous box and the muscles of the face were violently agitated4 ,some of the spectators even imagined that the corpus callosum itself was affected by a peculiar convulsion2 but it is possible that this emotion was owing to a mechanical impulse which shook the whole head4 ,new experiments will1 therefore1 be necessary before any thing further can be said in regard to this observation4 ,,experiment ,,xxx4 ,having carried the dissection to the olfactory nerves1 and even to the crossing of the optic nerves1 ,i formed an arc from these parts to the lips and the eyes1 and obtained contractions1 but very weak in comparison of the preceding4 ,i observed that on touching the optic nerves with one of the arcs no sensible convulsions were produced in the eye-lids4 ,,experiment ,,xxxi4 ,this mutilated head1 which had been so long the subject of observation1 was united by the plane of the section to that of the other criminal1 which had not been subjected to anatomical dissection4 ,i then applied two arcs1 making one of them to communicate with the summit of the pile and the right ear of one head1 and the other with the bottom of the pile and the left ear of the second head4 ,both heads experienced contractions similar to those described in the #bgth experiment2 but in the head which had already been employed they appeared to be weaker4 ,,experiment ,,xxxii4 ,after these experiments on the head1 ,i proceeded to the trunk of the second criminal1 which ,i conceived to be most proper for my purpose4 ,i think it necessary here to observe1 that the body had been exposed for about an hour1 in an open court1 where the temperature was two degrees below zero4 ,the muscles of the fore-arm and the tendinous parts of the metacarpus being laid bare1 an arc was established from those muscles to the spinal marrow4 ,in consequence of this arrangement1 the fore-arm was raised1 to the great astonishment of those who were present4 ,,experiment ,,xxxiii4 ,having established an arc between the biceps muscle of each arm1 which ,i had laid perfectly bare1 ,i obtained similar contractions1 but somewhat weaker than in the preceding case4 ,,experiment ,,xxxiv4 ,having laid bare the tendons of the fingers1 on the back of the hand1 ,i established an arc between that region and the spinal marrow1 and obtained strong contractions in the fingers and in the whole hand4 ,,experiment ,,xxxv4 ,proceeding to the lower extremities1 ,i formed an arc from the spinal marrow to the vastus internus1 vastus externus1 sartorius1 and other muscles1 and obtained strong contractions in all these muscles4 ,having removed the arcs and the pile1 the muscles retained a small oscillatory motion1 which continued for ten minutes4 ,i observed the same phnomenon in the muscles of the neck1 when ,i established an arc between the spinal marrow and various other parts of the trunk4 ,,experiment ,,xxxvi4 ,having applied the arc to the spinal marrow and the uncovered muscles of the under part of the tarsus of the right foot1 the extensor muscles of all the toes1 and particularly of the great toe1 experienced very sensible contractions4 ,i repeated the experiment with the arc applied1 not to the spinal marrow1 but to the uncovered muscles of the thigh1 employed in the preceding experiment1 and found the contractions excited to be much stronger4 ,in like manner1 the muscles of the soles of the feet1 when ,i established an arc between them and the muscles of the thigh1 manifested much stronger contractions than when the arc extended to any other distant part4 ,,experiment ,,xxxvii4 ,having examined the force of the contractions1 when the arcs were applied to the surface of the muscles of the extremities1 ,i tried what effect would be produced by introducing them into their substance4 ,in this case1 the energy of the contractions was much increased4 ,,experiment ,,xxxviii4 ,after trying the action of ,galvanism on the extremities1 ,i resolved to examine the trunk4 ,with this view1 having established an arc from the spinal marrow to the muscles of the diaphragm1 ,i obtained very sensible contractions every time the arc was applied4 ,,experiment ,,xxxix4 ,i then caused the thorax to be opened1 that ,i might try the effects of ,galvanism on the most important of all the muscles1 the heart4 ,the pericardium having been detached1 ,i applied the conductor to the principal organ of life1 and ,i even caused it to be opened1 to examine whether there existed in any of its folds some fibre susceptible of oscillation2 but my researches were fruitless4 ,this insensibility ought1 perhaps1 to be ascribed to the want of a certain degree of heat and of animal moisture1 not to be found in a body two hours after death4 ,it will1 therefore1 be proper to repeat this experiment1 taking care to observe all those conditions which may be necessary to ensure its success4 ,,experiment ,,xl4 ,in the preceding experiment ,i observed that the diaphragm contracted1 and that the blood1 which after this phnomenon ,i supposed to be coagulated1 flowed on the contrary from the vena cava inferior1 and the jugular veins1 the moment the arc was applied1 and appeared of a bright red colour4 ,is there reason to conjecture that1 though great contractions cannot be produced1 it is possible to excite in the interior parts of the heart some oscillations analogous to those which ,i observed in the muscles of the thigh and neck8 ,this question can be determined only by new experiments4 ,,experiment ,,xli4 ,i observed in these experiments1 that the more the points of contact of the arc with the biceps muscle were multiplied1 the more the motion of the arm was extended2 especially when care was taken to insulate the muscle by removing the integuments1 and surrounding it with the wire bent in the form of a ring4 ,having applied arcs to the biceps muscle of each arm1 ,i was much surprised to see the fore-arm and hand of the extremity1 where the before-mentioned ring was placed1 rise quickly to the height of about six inches4 ,,experiment ,,xlii4 ,i repeated the experiment1 forming the arc from the biceps muscle of the fore-arm to the spinal marrow4 ,by these means contractions so violent were excited1 that the anterior part of the arm1 the whole of which lay extended in a horizontal position1 rose seven inches above the plane of the table4 ,having placed on the palm of the hand a metallic body1 such as a piece of money1 the hand at first supported it for a little time2 but at a certain degree of elevation it projected it to some distance4 ,i then substituted for the piece of money a pair of iron pincers1 about half a pound in weight2 the hand rose up and seemed to seize them2 but at the highest degree of elevation the contraction ceased1 and the pincers fell4 ,i observed that the weight with which the hand was loaded1 diminished the elevating power of the arm very little4 ,it may be proper to remark1 that the last two experiments were performed an hour and a quarter after the execution1 and those on the lower extremities almost two hours4 ,if this experiment were speedily repeated1 in order to take advantage of the highest degree of vitality1 loading the hand with different weights in succession1 till the motion of the hand should be totally impeded1 ,i am of opinion that an estimate might be formed of the elevating force1 according to the different degrees of vitality4 ,in the preceding experiments ,i have omitted certain observations1 which did not agree with those made on other warm-blooded animals4 ,but my silence deranges no theory2 and1 besides1 facts not sufficiently confirmed would have led me into physiological discussions of little utility1 as these points can be determined only by new experiments4 ,it is painful to a philosopher to reflect1 that his doubts cannot be cleared up until new victims shall fall under the sword of justice2 but the hope that his researches may lead to some new discovery beneficial to mankind1 in a physiological point of view1 lessens in a certain measure the disagreeable sensations excited by these melancholy scenes4 ,an assassin decapitated at ,bologna1 in the month of ,january #ahjb1 afforded me an opportunity of verifying the truth of my former observations4 ,in my first experiments on the human body1 the dura and pia mater had been so little affected1 that several of those present concluded that these parts were absolutely insensible to the action of the ,galvanic pile2 and this opinion was still further strengthened by the authority of several able anatomists4 ,on the other hand1 many warm-blooded animals1 as will be seen hereafter1 afforded contrary results4 ,it is certain that nature1 which is always consistent with itself in the action of that general principle which excites the muscular forces1 ought to exhibit in the human body the same phnomena as those which constantly occur in other warm-blooded animals4 ,i mentioned this anomaly to several of my colleagues1 and particularly to that able anatomist ,mondini1 who1 having made researches on this subject1 communicated to me the result of them1 and directed all the preparations necessary for the following experiments1 modified according to the general views collected in the preceding observations4 ,,experiment ,,xliii4 ,the body of the criminal having been removed from the place of execution to a neighbouring apartment1 the trunk was placed on one table1 and the head on another4 ,on the latter stood a pile1 composed of a hundred plates of zinc and copper1 and on the former1 a pile of a hundred plates of silver and zinc4 ,this apparatus tended greatly to facilitate the rapid performance of the experiments1 which were made at the same time on all the parts of the body1 and enabled us to take advantage of its great vitality4 ,i had with me a select company of young physicians and surgeons1 who1 being much interested in the progress of ,galvanism1 assisted me with great ardour4 ,they were divided into two parties1 each of which was stationed around one of the tables1 in order that the operations performed at the one might not interrupt those at the other4 ,to gratify ,professor ,mondini1 who was desirous of seeing the muscular action in the whole head1 an arc was established from the spinal marrow to one of the ears1 the pile being interposed between them1 and strong contractions were produced in the whole face1 as had been the case in all the other animals4 ,,experiment ,,xliv4 ,having sawn through the scull with every possible precaution1 and an arc being established from the dura mater to one of the ears1 the usual contractions ensued4 ,the pia mater was then uncovered1 and1 by employing the same means1 the same results and the same effects were produced as had been obtained in other animals4 ,,experiment ,,xlv4 ,the cortical substance in the left hemisphere was uncovered1 and an arc being extended from it to the right ear1 the movements of the face were exceedingly sensible in the part opposite to the uncovered hemisphere4 ,i repeated the experiment different ways with the same results1 and found1 as ,i suspected1 that this process put an end to the anomaly observed in regard to the membranes and cortical substance1 which at first seemed to withstand the general action of the ,galvanic fluid1 though it produced an effect on the other parts of the brain4 ,dr4 ,mondini took care to remove the superfluous moisture1 both from the membranes and cortical substance1 in order to prevent all suspicion that it might facilitate a communication1 in any manner1 with the medullary substance4 ,,experiment ,,xlvi4 ,dr4 ,mondini1 with his usual ability1 having exposed in the brain the medullary substance1 the corpora striata1 the corpus callosum1 the thalami nervorum opticorum1 and the cerebellum1 and an arc being formed of all these parts1 we fully confirmed the results of the experiments which had been before made on the bodies of other criminals4 ,,experiment ,,xlvii4 ,having observed these phnomena in the head1 we proceeded to the trunk1 which gave us results no less interesting4 ,the body was sound and robust1 and indicated a constitution replete with vital energy4 ,by forming an arc from the spinal marrow to the biceps muscle1 very strong movements were produced throughout the whole body1 and particularly in the arm1 which could not be bent without very great exertion4 ,,experiment ,,xlviii4 ,by again applying the arc1 according to the method detailed in the #dast experiment1 the violence of the contractions was much increased4 ,the trunk was thrown into strong convulsions2 the shoulders were elevated in a sensible manner2 and the hands were so agitated that they beat against the table which supported the body4 ,,experiment ,,xlix4 ,a silver probe was inserted into the spinal marrow1 and one of the hands immersed in a solution of muriate of soda4 ,i then applied one extremity of the arc to the most distant part of the probe1 and the other to the surface of the water1 by which means the ,galvanism was made to exercise its action without any immediate contact of the animal parts4 ,when this arrangement was formed1 the arm1 which hung over the edge of the table1 moved towards the breast1 passing over the space of about a foot and a half4 ,by employing1 at the same time1 the two piles composed of a hundred plates of copper and zinc1 the contractions were much increased4 ,but this augmentation of force did not exactly follow the ratio of the combined activity of the two piles united4 ,,experiment ,l4 ,by forming an arc from the feet to the spinal marrow1 first applying armatures1 and then employing a solution of muriate of soda as in the preceding experiments1 ,i obtained contractions1 but weaker than those in the upper extremities4 ,as there was reason to suspect that this diminution arose in part from the position of the trunk1 ,i placed the body in such a manner1 that1 while the thighs rested on the edge of the table1 the legs1 which hung over it1 were at full liberty to move4 ,this difference in position produced a difference in the results2 and ,i intend to repeat the experiment1 according to this arrangement1 applying the arc directly to the crural nerves4 ,,experiment ,,li4 ,a small portion of the great pectoral muscle being detached from the ribs1 and exposed to the action of the pile1 exhibited strong contractions1 and the motion of the diaphragm was also very remarkable4 ,the heart alone1 though carefully subjected to all the operations detailed in the #dgth experiment1 remained perfectly motionless4 ,,experiment ,,lii4 ,having brought the separated head near to the neck of the trunk1 ,i established a communication between it and the trunk by means of the animal moisture alone2 and an arc being then formed from the head to different parts of the trunk1 sensible contractions were produced1 and particularly in the latter4 ,this observation seems still further to prove that an arc of moisture has power to excite muscular contractions4 ,in this1 as well as in the preceding experiments1 if any of the spectators1 while an arc was established by means of the pile1 brought a frog prepared in the usual manner near to the human body1 the frog experienced strong contractions1 though at a distance from the place to which the action of the ,galvanism was determined4 ,,experiment ,,liii4 ,after three hours had been employed in these experiments1 ,i conceived the idea of trying the action of ,galvanism on some parts of the body separated from the trunk4 ,one of the legs1 therefore1 was amputated six inches above the joint of the knee2 and an arc being established from a point in the plane of the section to the knee1 ,i obtained contractions similar to those which had been produced before the limb was separated from the body4 ,i then formed an arc of moisture1 by applying the amputated limb to the trunk2 and having determined the action of the pile to the spinal marrow and the foot1 ,i obtained very sensible contractions4 ,i observed1 on this occasion1 that a frog1 prepared some time before1 and which was accidentally lying on the table1 at each application of the metallic arcs moved like an electrometer1 and thus confirmed the action of an arc of moisture4 ,,experiment ,,liv4 ,after a considerable time had been employed in the preceding experiment1 ,i endeavoured to revive the action of the ,galvanism by moistening the muscles with a solution of opium4 ,by these means the contractions seemed to be increased2 and the case was the same in other warm-blooded animals4 ,a series of similar experiments1 if carefully made1 would no doubt be attended with important results2 as they might enable us to ascertain the action of the different stimulants proposed by ,dr4 ,brown4 ,but ,i must1 in the mean time1 observe1 that the before-mentioned effects of opium fully correspond with those long ago observed by ,galvani4 ,it results1 in general1 from my experiments1 that moisture performs a conspicuous part in producing contractions2 and that it is even of more importance than animal heat4 ,i indeed find that muscular contractions may be obtained after the body has thrown out a great deal of its heat1 even when it has cooled for several hours1 and when it has been exposed to a temperature below zero2 for1 if ,galvanism be communicated to a body in that state1 muscular contractions will be immediately excited2 but they soon cease by the privation of animal moisture4 ,if a muscle1 indeed1 which has been laid bare resists the ,galvanic influence1 its action may be speedily renewed by making an incision into it1 or into some of the muscles which surround it4 ,i can assert1 that by this process partial contractions were produced in the human body five hours after death1 every time that the arcs were applied to the muscular fibres4 ,being worn out with this long series of experiments1 ,i found it necessary to abandon them2 but1 from the force of the contractions1 it could easily be seen that they might have been produced much longer4 ,having communicated these results to the celebrated ,caldani1 ,professor of ,anatomy in the ,university of ,padua1 he requested that ,i would confirm the observations ,i had made by again applying ,galvanism to the membranes and to the cortical substance of the brain4 ,he was unwilling to give up the system of ,haller without very positive proofs2 and his doubts were to me of great utility1 as they induced me to establish the action of ,galvanism on these parts by the following experiments3 ,,experiment ,,lv4 ,as these doubts related to a delicate point1 which would have produced some variation in the theory of a celebrated physiologist1 ,i repeated the experiment on the head of an ox newly killed1 in the presence of ,professor ,mondini1 who made the necessary preparations4 ,the dura mater was laid bare2 and the action of the ,galvanism being conducted to it1 strong contractions were immediately produced4 ,the same phnomenon took place when the cortical substance was brought into contact with one of the arcs4 ,i repeated this experiment with the same success on the heads of several oxen and lambs4 ,,experiment ,,lvi4 ,when ,i passed through ,turin1 ,professors ,vassalli1 ,giulio1 and ,rossi requested me to perform1 in their presence1 my principal experiments1 and those in particular which related to the membranes and the cortical substance of the brain4 ,they observed1 at the same time1 that in uncovering the brain of an ox with a cleaver1 some derangement1 in consequence of the agitation1 might be effected in that organ1 which would perhaps produce an alteration in the results4 ,professors ,giulio and ,rossi proposed therefore to uncover the brain by the trepan1 which gave a greater degree of precision to the experiment4 ,the dura mater of an ox being uncovered in this manner1 it was subjected to the action of ,galvanism1 and even with this mode of preparation the muscular contractions every time the arc was applied were pretty strong4 ,the arc being determined to the cortical substance1 the force of the contractions seemed to be increased2 and in general they appeared to be more considerable in proportion as the arc was plunged to a greater depth into the substance of the brain4 ,these gentlemen1 in whose presence ,i performed my principal experiments1 having pursued my method after my departure1 made some observations which may be of great use to physiology4 ,they had before entertained strong doubts whether the heart was susceptible of the ,galvanic action1 by means of simple armatures applied to the different parts of that muscle2 and such irregularity had been observed in the results1 that it appeared difficult to determine the question4 ,i was therefore exceedingly happy that ,i had had an opportunity of exciting in others a desire to make new researches in regard to this point1 of so much importance4 ,professors ,vassalli1 ,giulio and ,rossi repeated and modified my experiments on the heart in such a manner1 that they obtained in man1 and warm-blooded animals1 contractions similar to those which ,i had observed only in cold-blooded animals4 ,i wait for a detailed account of these experiments1 as well as of others made on decapitated criminals#b1 which were subjected to my processes4 ,the bodies were removed to the large hospital2 and notwithstanding the long period which had elapsed between the time of the execution and that when the experiments were performed1 they observed almost the same phnomena4 ,the observation made on this criminal1 that the vital powers exist so long in the body after death1 induces me to hope that ,i shall be able to obtain similar results by the application of my method1 in common cases of suspended animation4 ,but when employed for this laudable purpose it should be modified in such a manner as to render unnecessary those operations which are so painful to humanity4 ,on this account1 ,i have invented a method by which muscular contractions may be produced without the least incision or separation of the muscles4 ,it is so combined1 that it cannot be rejected by the most rigorous medical jurisprudence4 #b ,some account of the latter1 from the ,journal de ,physique1 will be found in the ,appendix4--,,trans4 ,,experiment ,,lvii4 ,in order to try the vital force existing in the human body after death1 ,i immerse the hand in a solution of muriate of soda1 and establish an arc1 one of the extremities of which is made to pass round the fore-arm1 while the other is brought into contact with the bottom of the pile4 ,i adapt to the extremity of another arc an elastic probe1 which is applied to one of the ears1 moistened by means of a syringe with the same solution1 and connect the other extremity of the arc with the summit of the pile4 ,by this arrangement various contractions1 according to the different degrees of vitality in the bodies1 are observed1 sometimes in the fingers1 sometimes in the hand1 and sometimes in the whole arm4 ,the fingers bend1 and move in a sensible manner2 and sometimes the whole of the fore-arm proceeds towards the breast4 ,the importance of this method for determining the duration of the vital powers after death may be readily comprehended4 ,should means be found hereafter to make further discoveries in regard to this interesting point1 physiologists may then be able to determine with certainty those cases when interment ought to be retarded2 and those where the good of society requires that every possible means of resuscitation should be employed4 ,in the large hospital of ,bologna1 ,i made several observations on this subject2 and remarked in particular1 how much the nature of the disease contributes1 cteris paribus1 to produce a difference in the duration of the muscular contractions4 ,i tried the case of death produced by putrid fevers1 by pleurisies1 by wounds in the pericardium1 by the scurvy1 and by the consequences of parturition2 and ,i found a great difference in the degrees of vitality1 according to the circumstances of the disease1 the age and temperament of the individual2 which confirms me in the opinion ,i entertain1 that these experiments1 if long continued without intermission by able physiologists1 might be of the greatest benefit to medicine4 ,these researches are not an object of mere curiosity2 they seem to open an extensive field for promoting the welfare of the human race1 and may be of service in cases of apparent death1 occasioned by an alteration of the brain1 and sometimes in cases of asphyxia4 ,various learned academies are entitled to great praise for having turned their attention to this subject1 and for having already recommended different stimulants as proper for being used on such occasions4 ,but ,i must take the liberty of requesting that in similar cases the action of ,galvanism maybe tried1 by employing the new method here proposed4 ,it is of great importance that the means of affording relief to the sufferings of mankind should be multiplied1 and especially in cases in which the old system of medicine presents to us so few resources4 ,in the mean time ,i conceive it may be useful to make some trials on animals thrown into a state of asphyxia different ways4 ,these researches may lead to valuable discoveries1 and produce some light to direct us in our attempts to save the lives of men4 ,if the encouragement ,i have received from the medical and philosophical world1 in general1 induce others to pursue the same path1 it will give me great satisfaction4 ,galvanism is yet in its infancy2 and when we reflect on the slow progress which many other branches of science have made1 and how long they remained almost stationary before the full importance of them was known1 it would be presumption to set bounds to that which is the subject of the present work4 ,for my part1 ,i spared no pains during my short stay at ,paris to exhibit my method1 and to make it publicly known4 ,dr4 ,pinel assisted at my experiments with the utmost zeal1 and was witness to muscular contractions excited in the body of an old woman1 who had died of a malignant putrid fever4 ,the interest which he took in my researches induced me to communicate to him several plans ,i had formed for giving relief to some of those unfortunate beings committed to his skill and beneficent care in the ,hpital des ,foux4 ,i pointed out to him some particular cases where the individuals1 in consequence of a deep rooted melancholy1 were reduced almost to a state of idiotism1 and in which ,galvanism seemed likely to be attended with the greatest benefit4 ,in the last public sitting of the ,institute of ,bologna1 at which ,i was present1 ,i announced the complete cure of two lunatics performed in the ,public ,hospital1 in the presence of many of the medical pupils1 and with the assistance of the professors who superintend that establishment1 and who are now employed in confirming my method on other patients4 ,i am well aware that two cures are not sufficient to make operations of this kind be admitted as general remedies2 but they ought to encourage physicians to prosecute this subject in order to ascertain how far ,galvanism can be considered as of utility in such cases1 and to endeavour by their labours to fill up the vacuity which still exists in this part of medicine4 ,i am ready to acknowledge that great caution ought to be employed in performing such experiments2 and for this reason ,i purpose1 in the third part of the present work1 to lay before the reader the reflections and observations of various ingenious men who have made this department of ,galvanism an object of their researches4 ,but before ,i proceed further1 ,i think it necessary to deduce from what has been already said a few general corollaries4 ,,corollary ,i4 ,the muscles are affected by the action of the pile in a much more powerful manner when they are laid entirely bare1 and when the arc is made to penetrate to a considerable depth in their substance4 ,,corollary ,,ii4 ,these convulsions are increased in proportion to the number of the points of contact between the arc and the muscle4 ,,corollary ,,iii4 ,in many cases1 muscular contractions are obtained by forming an arc from one muscle to another4 ,,corollary ,,iv4 ,muscular contractions are almost always speedily obtained by the pile1 even when the means proposed by ,haller fail to produce them4 ,,corollary ,v4 ,the heart1 which1 according to ,haller's principle1 is the first muscle that receives life and the last to lose it1 in comparison of the other muscles1 can with difficulty be made to feel the influence of the ,galvanic action2 while the other muscles always retain1 a long time after death1 that vital force which it has never been found possible to excite but by the impulse of ,galvanism4 ,,corollary ,,vi4 ,the partisans of ,haller1 to excite these contractions1 often employ stimulants1 which alter the texture of the muscular fibre1 and destroy its continuity2 an inconvenience which may be avoided by applying ,galvanism4 ,,corollary ,,vii4 ,as the kinds of apparatus before mentioned are not applied to the spinal marrow alone1 but to the different nerves of the animal machine1 they may afford to the anatomist an experimental myology2 by means of which he can render sensible to the eye the fixed and moveable points of the muscles1 and the real extent of their action4 ,,corollary ,,viii4 ,the experiments made on the bodies of persons who died a natural death1 are of the greatest importance to physiology4 ,i am strongly inclined to think that1 by pursuing these researches more in detail1 they will one day make us better acquainted with the character of the vital powers1 and the difference of their duration1 according to diversity of sex1 age1 temperament and disease1 and even according to diversity of climate and to the nature of the atmosphere4 ,,part ,,the ,,third4 ,,on ,,the ,,power ,,of ,,galvanism ,,as ,,applied ,,to ,,medicine4 ,if the doctrine of ,galvanism have thrown considerable light on various parts of philosophy and chemistry1 it gives us reason to hope that it may also be of benefit to medicine4 ,the labours indeed of ,galvani1 whose most ardent desire was that his discovery might be rendered useful to mankind1 were at length directed to this object1 and his wishes now begin to be realized2 but ,i must request the reader not to be too sanguine in his expectations1 or to imagine that ,i here mean to entertain him with a long series of wonderful or extraordinary cures performed by means of ,galvanism4 ,i have no intention to decorate the discovery of my late uncle with false glory4 ,though ,i possess neither the same depth of knowledge1 nor the same superiority of talents1 ,i have always endeavoured to imitate his moderation and prudence in the application of his theory4 ,i am fully convinced that much still remains to be done1 in order to discover the best methods of employing this new agent2 and that the facts respecting it1 though numerous1 have not been reduced to principles sufficiently certain and satisfactory4 ,there are1 nevertheless1 some results and observations exceedingly curious1 which1 if confirmed by new experiments and researches1 may enable us to obtain convincing proofs of its utility4 ,new facts1 however surprising1 are not to be despised merely on account of their being different from any before observed4 ,those who reject them1 as some have done1 ought first to show that they are inconsistent with the principles of sound philosophy4 ,guided by these reflections1 and desirous of contributing1 as far as possible1 towards the illustration of a new and very obscure subject1 ,i shall lay before the reader the result of my researches in the following articles4 ,,section ,i4 ,advantages which the medical administration of ,galvanism has over that of common electricity4 ,several reasons have induced me to prefer the medical administration of ,galvanism by means of the pile1 to that of artificial electricity4 ,in regard to the action of the common electric machine1 the difficulty of calling it forth properly during damp weather2 the time required for exciting it2 the necessity of charging the jar every time it is applied to the patient1 are so many obstacles which render the administration of common electricity inconvenient2 and on this account it is now much less used than formerly4 ,on the other hand the pile1 according to the observations which ,i have had an opportunity of making1 acts in a uniform manner2 is not sensible to the effects of moisture2 and forms a sort of ,leyden flask1 which has a continued action that may be a long time employed4 ,it may be considered as an apparatus1 which in itself contains a series of jars charged in succession with different degrees of electricity4 ,i might here enumerate many differences which are found between the administration of ,galvanism and that of electricity4 ,if electricity be administered to a patient directly from the conductor1 he receives very little of its action2 if a shock be given with the ,leyden flask1 the action is exceedingly strong1 but not permanent4 ,on the other hand1 the pile has a strong and continued action1 and occasions a powerful circulation of the ,galvanic matter1 which after some time produces very striking effects on the animal fluids4 ,i might here refer1 by way of example1 to the experiments made with ,galvanism on the blood1 the bile1 and the urine1 which gave results ,i was never able to obtain by common electricity4 ,i shall mention1 in the last place1 the great convenience of the pile1 and the short space of time in which ,galvanism may be administered by it to a great number of persons2 and this advantage is sufficient1 cteris paribus1 to render it preferable in this respect to common electricity4 ,,section ,,ii4 ,application of ,galvanism to the organs of hearing and of sight4 ,by applying ,galvanism to different parts of the face1 a flash of light is excited in the eyes1 which is stronger or weaker according to the nature of the parts to which it is directed4 ,these organs1 though delicate1 are always affected in such a manner that the mechanism of the eye sustains no injury from the metallic arcs when they are made to communicate with only two plates of different metals4 ,i received an account of this phnomenon at ,milan1 several years ago1 from the celebrated ,volta1 who produced it by applying a conductor of zinc in such a manner1 that one end of it touched the bulb of the eye1 and the other the tip of the tongue armed with a plate of tin4 ,in administering ,galvanism for diseases of the eyes1 it is much better to employ the pile4 ,to excite the appearance of a flash of light1 it is not necessary that the eyes should be open2 it takes place even if they are shut1 and covered with a bandage in a darkened apartment4 ,some of the partisans of ,euler1 perhaps1 may here maintain1 that this phnomenon of ,galvanism is a deception1 and that no light can be really excited in such cases1 as the production of light depends on the emanation of rays from a luminous body which penetrate into the interior part of the eye4 ,but without entering into the examination of this question1 which is foreign to my principal object1 ,i shall only observe1 that long before the theory of ,galvanism was known1 the celebrated ,darwin had found that when the eyes are shut1 there are certain internal stimulants which are capable of producing the appearance of light and of colours4 ,in no case is the difference between ,galvanism and electricity more apparent than in the application of the former to the sight4 ,very little benefit had been obtained by means of a metallic point inclosed in a glass tube1 which directed the electric charge from a jar to the cornea2 and besides1 the shock of a ,leyden jar applied directly to so delicate an organ as the eye could not but be attended with danger4 ,galvanism applied to the exterior part of the eye1 in the same place where a stream of electricity would have had no influence whatever1 has always produced a certain effect on the organ of sight1 as is proved by the following experiments4 ,,experiment ,i4 ,if you touch with one hand the bottom of the pile1 and at the same time apply to the summit different parts of the face moistened with salt water1 a flash of light will be excited in the eyes4 ,the same result will be obtained1 if instead of touching the bottom of the pile with the hand you touch it with the sole of your foot4 ,no flash of light is observed when the ,leyden flask is employed in the same manner4 ,,experiment ,,ii4 ,having observed the preceding phnomenon in myself1 and excited it in others1 ,i was desirous of proving it in regard to several persons at the same time during the course of my public lectures1 and for that purpose ,i made use of the following apparatus4 ,i arranged two metallic plates in a horizontal position1 at the distance of nine inches from each other1 so that six persons with their hands dipped in salt water could touch the lower plate1 and the upper one with the tips of their tongue4 ,a charged ,leyden flask placed between the two plates being then discharged1 the whole of the persons experienced a violent shock1 but perceived no flash of light4 ,it is well known however that1 when a similar arc is formed with the interposition of a very strong pile1 a flash of light is constantly observed2 though the force in the second case is much less than that excited by the explosion of the ,leyden flask4 ,the same result will be obtained by bringing the upper plate into contact with the nose4 ,,experiment ,,iii4 ,as my pupils took much interest in this research1 some of them suspected that the light of the apartment might perhaps have effaced that excited by the electricity4 ,i therefore made the apartment entirely dark2 and one of them taking a ,leyden flask applied it to the point of the nose of another person with whom he was in communication1 by laying hold of him with the other hand4 ,by these means a very strong shock was given1 but no flash of light was observed4 ,this experiment was repeated1 making the person who received the shock of the ,leyden flask to remain some time before in the dark1 that his eyes might be better enabled to perceive any faint light that might be excited3 but the result was still the same4 ,to those who refer ,galvanism to the common laws of electricity1 it will be difficult to comprehend the cause of the different action exercised by the latter on the organ of sight4 ,but as it is not my intention at present to enter into any discussion on this subject1 ,i shall leave it to philosophers to assign a reason for this phnomenon1 and only observe1 that the properties above indicated will be sufficient to authorize medical practitioners to prefer1 in certain cases1 the administration of ,galvanism by the pile to that of common electricity4 ,before ,i proceed directly to the medical administration of ,galvanism to the organ of sight1 ,i think it necessary to distinguish four classes of blind persons whose cases ought to be considered separately4 ,the first belongs to those who from their birth have been deprived of the valuable blessing of sight4 ,the second comprehends those become blind in consequence of some great lsion1 or some derangement in the solids or in the fluids which constitute the mechanism of the eye4 ,the third1 those who have become blind by some morbid action1 though the mechanism of the eye has been little affected1 and though no impediment has occurred but in regard to the action of the optic nerve4 ,the fourth class comprehends those who1 though not actually deprived of sight1 have it much weakened in consequence of disease1 or of some other cause4 ,the administration of ,galvanism does not hold forth much hope of a cure to persons belonging to the first two classes4 ,i however resolved to attempt some experiments on this subject at ,bologna2 but though there were a great many blind in that city1 ,i found that they had become so by the malignant influence of the small pox4 ,this observation will1 ,i hope1 be of service to the pursuits of the celebrated ,dr4 ,jenner1 and of all those who exert themselves to promote the beneficial practice of vaccine inoculation4 ,being deprived1 at ,bologna1 of any opportunity of trying the effects of ,galvanism in cases of persons born blind1 ,i galvanised several who had lost their sight at a very early age4 ,i first applied the ,galvanism to the arms of five blind persons1 some of whom had lost their sight thirty1 and others forty years and even more4 ,by this method they were familiarised with the idea of its mechanical action1 and learned to distinguish it from every other sensation4 ,i then applied ,galvanism to the lips1 and to the tip of the nose1 in a darkened apartment2 but in three instances only the patients had a real perception of light1 to which they had been so long strangers4 ,i then applied it to cases of amaurosis1 and at first had confident expectation of effecting a perfect cure4 ,one of my patients was a woman1 whom this disorder had deprived of the sight of one eye1 while that of the other was much weakened4 ,after administering the ,galvanism different ways1 ,i observed that the eye totally blind began to have a perception of light1 and that the sight of the one which was weakened became much stronger4 ,i then took a book1 which ,i held at a considerable distance from her2 and removing it gradually further as the ,galvanism was administered1 ,i observed1 in consequence of this method1 that the patient's sight daily improved4 ,but ,i must freely confess that the success obtained1 though at first flattering1 was not of long duration2 and that when the ,galvanism was discontinued a great deal of the benefit which had been obtained was again lost4 ,on this account1 ,i was discouraged from administering ,galvanism any more in such cases4 ,i am however of opinion1 that by varying the method of administration it may be attended with some utility4 ,i shall here observe1 that having once had occasion to administer common electricity in a similar case of amaurosis1 ,i was never able to excite the perception of a flash in the eyes of the patient1 though the electricity was applied directly to the eye itself4 ,i have had few opportunities of applying ,galvanism in diseases of the organs of hearing4 ,besides1 ,i thought it almost needless to try a method which had been already brought to a state of perfection by some of the most celebrated professors of ,germany and ,berlin4 ,i admired in particular a very ingenious machine1 invented for that purpose by a ,german philosopher1 and lately constructed in ,england by ,mr4 ,john ,cuthbertson1 an eminent philosophical and mathematical instrument maker1 and celebrated for having constructed the large electrical machine of ,harlem4 ,the apparatus consists of a metal lever1 which by means of certain wheels and machinery rises and falls every minute or second1 and at each time of falling forms a communication between certain parts of the patient and the pile4 ,in consequence of this arrangement1 the interrupted action of the ,galvanism is renewed every time that the communication between the patient and the pile is re-established4 ,before my departure from ,london1 ,i made several changes and improvements in the usual construction of this apparatus1 in order to give it as much simplicity as possible4 ,the following is the manner in which ,i caused it to be constructed lately for my own use4 ,one extremity of the lever which forms the communication 7,plate ,,iii4 fig4 #a471 is fixed to the base or negative end of the pile1 and the other terminates in a small hammer1 so placed as to strike a bell1 which by means of a bason of water is in communication with certain parts of the patient1 while an arc extends from the patient to the summit or positive end of the pile4 ,in consequence of this arrangement1 every time that the small hammer strikes the bell the ,galvanic action of the pile is repeated4 ,in cases of deafness1 ,i cause the patient to hold in one hand an insulated metallic arc1 one end of which is brought into contact with the affected ear1 and the other with the positive end of the pile2 and to immerse the other hand in a bason of salt water placed above the bell4 ,when this disposition has been made1 the wheel-work is turned round1 which gives motion to the lever2 and every time that the hammer strikes the bell1 a communication is formed between the positive and negative ends of the pile3 consequently there will then be a circulation of the fluid1 and the ,galvanism will exercise a direct action on the organ of hearing4 ,the apparatus1 constructed in this manner1 appears to me to be reduced to great simplicity3 and therefore ,i propose to extend the use of it1 by employing it to administer medical ,galvanism to other diseased parts of the body4 ,before ,i conclude this article1 ,i must suggest a hint respecting the application of ,galvanism to diseases of the teeth1 founded on information communicated to me on this subject by ,mr4 ,fowler1 an eminent dentist of ,london4 ,when the caries is concealed from the sight1 ,mr4 ,fowler employs the following method to discover the affected tooth4 ,he first insulates the patient2 and having put into his hand the electric chain1 he applies a small piece of wire to the dens sapienti1 drawing it gradually over its surface3 he then applies it to the next tooth1 repeating the operation1 and proceeds in like manner with the rest till he comes to the diseased tooth1 which discovers itself by a violent pain producing an involuntary commotion in the body4 ,it is always remarked1 that when this tooth is extracted it exhibits a carious part not before visible4 ,this method1 therefore1 is of great importance1 as it frequently happens in such cases that the dentist1 not being able to distinguish the diseased tooth from the rest1 is obliged to draw some that are sound before he can discover it4 ,,section ,,iii4 ,application of ,galvanism in cases of asphyxia and drowning4 ,i mentioned in the second part of this work the great influence which ,galvanism has in cases of asphyxia1 and the preference which ought to be given to it in comparison of other stimulants4 ,though the observations offered in that part are sufficient to prove my proposition1 ,i shall add to them the following experiments3 ,,experiment ,i4 ,some dogs and cats were immersed in a large pond till they gave no external signs of respiration1 or of muscular motion2 and ,galvanism being immediately administered to them1 according to the methods already described1 they were sometimes restored to life4 ,i make use of the term #8sometimes1' because1 if animals are immersed in water for a longer period than their organization can bear1 and if the vital powers are really destroyed1 it is evident that it will be impossible to restore them to life by any physical process whatever4 ,i obtained the same results from to animals thrown into a state of asphyxia in different ways4 ,,experiment ,,ii4 ,having applied ,galvanism to the trunk of a dog1 in the ,hpital de la ,charit at ,paris1 air seemed to escape from the tracheal artery on every application of the arc4 ,being requested to repeat and confirm this interesting experiment1 ,i found myself under the necessity of sacrificing a new victim to my ,galvanic researches4 ,as it was necessary to examine the phnomenon while the body was in that state of vitality most proper for the observation1 ,i exposed the trunk of another dog recently killed to the ,galvanic action2 and having placed a taper near to the tracheal artery1 it was extinguished twice in succession by two applications of ,galvanism4 ,by repeating this experiment1 in ,mr4 ,wilson's anatomical theatre1 ,great ,windmill-street1 and in the theatres of ,guy's and ,st4 ,thomas's ,hospital1 ,london1 ,i found that the taper could be extinguished a greater number of times4 ,these experiments give me sufficient reason to hope that ,galvanism may be administered with some advantage in cases of drowning4 ,but as ,i never had an opportunity of trying the effects of this stimulant in such cases1 ,i have requested several medical practitioners to pay attention to this application of ,galvanism1 which may be of the utmost importance to the cause of humanity4 ,i have already mentioned that the method which ,i propose is exceedingly simple2 that no anatomical operation whatever is required2 that it is attended with no danger2 and that the possibility of saving the life is in every case respected4 ,nothing is necessary but to immerse in salt water one of the hands of the person subjected to the operation1 and then to apply the ,galvanic current to one of the ears and to the surface of the salt water4 ,dr4 ,lettsom1 a very zealous member of the ,humane ,society1 having been present at some of my experiments1 ,i requested that he would recommend the application of ,galvanism in cases of drowning4 ,he assured me that he would use his endeavours to cause my method to be tried1 and ,i had several conferences with him on the subject1 that ,i might communicate to him such information as might tend to facilitate the application of it4 ,as the ,galvanism in such cases ought to be administered with great promptitude1 we agreed that the apparatus of the trough is preferable to that of the pile2 and we contrived the plan of a portable box to contain a trough1 two arcs1 and a solution of common salt4 ,such an apparatus will be exceedingly convenient1 and may easily be employed in all cases of drowning and of asphyxia4 ,,section ,,iv4 ,galvanism applied to the cure of melancholy madness4 ,hospitals for lunatics present a spectacle which must excite compassion in every breast not void of humanity1 as they are in general crowded with unfortunate beings1 useless to themselves and dangerous to others2 while little hope is left of their being ever restored to society4 ,this is the case in particular with persons subject to melancholy madness2 on some of whom ,i tried last year the effects of ,galvanism4 ,in consequence of a long series of painful and disagreeable experiments made on myself1 ,i was induced to entertain great hopes from this remedy4 ,i applied it to my ears and to different parts of the head1 in order that ,i might form a just estimation of its power and influence on the brain4 ,it is well known that the strength and energy of the operations of the mind depend on the state of the functions of the brain4 ,it is well known also1 that a violent fall1 or strong impression on the head1 has often occasioned great variations in the intellectual faculties4 ,by such accidents some have entirely lost the power of imagination2 while1 on the other hand1 some have acquired very great talents1 or emerged from a state of complete stupidity4 ,these considerations gave me reason to hope that the power of ,galvanism might perhaps be able to produce a salutary change in the brain in cases of melancholy madness4 ,i communicated my thoughts on this subject to the physicians who superintend the hospital for lunatics at ,bologna4 ,they approved of my ideas1 and gave me every assistance in their power to enable me to prosecute my researches4 ,in their presence1 and under their direction1 ,i administered ,galvanism to several lunatics1 applying it different ways2 and the result was the complete cure of two who had laboured under melancholy madness4 ,as the method ,i followed in both cases was nearly the same1 ,i shall here give a description of it1 as it may serve as a general rule for the administration of this remedy under similar circumstances4 ,louis ,lanzarini1 of a phlegmatic temperament1 twenty-seven years of age1 and a farmer by profession1 fell into a state of deep melancholy1 which first announced itself by an attack of fever2 in consequence of which he was conveyed to the public hospital of ,st4 ,ursula on the #agth of ,may #ahja4 ,when he arrived there1 he began to complain of the treatment he had received1 and to show great uneasiness2 by which means his melancholy increased so much1 that it at length degenerated into real stupidity4 ,while in this state1 ,professors ,gentilli and ,palazzi were so kind as to allow me to administer ,galvanism to him2 which ,i did in the presence of these physicians1 and of several medical students who attended the hospital4 ,i had provided for this purpose a pile composed of eighty pieces of silver and zinc1 and ,i at first administered the ,galvanism gradually1 forming the arc by means of the hands4 ,lanzarini1 in a state of the utmost dejection1 viewed the apparatus and the company present with his eyes fixed and motionless4 ,when interrogated by the physicians and myself in regard to the origin of his malady1 he gave laconic and confused answers1 which seemed to indicate a great degree of stupidity and derangement4 ,i first moistened his hands1 and formed an arc with the pile at different heights1 to accustom him to endure the action of the apparatus4 ,no change1 however1 was produced in the patient by this operation4 ,i then repeated the experiment1 placing his hands1 moistened with salt water1 at the bottom of the pile2 and conveying an arc from the summit of the pile to different parts of his face1 moistened with the same solution4 ,a change was soon observed in the patient's countenance1 and his whole demeanour seemed to indicate that the degree of his melancholy was somewhat lessened4 ,the experiment was repeated several times with the same success2 which seems to prove that ,galvanism absolutely exercises an action in such diseases4 ,the patient being interrogated next day1 asserted that he had felt no inconvenience from the application of the ,galvanism2 and this account was confirmed by the keepers1 who had been desired to give a report of the least change that might take place4 ,similar results were obtained by gradually administering the action of the pile with greater force for several days successively1 and we soon began to observe that it produced a very striking effect4 ,the patient1 on touching the apparatus1 seemed to acquire new spirits2 a smile appeared on his countenance1 and a complete change took place in his eyes as well as in every feature of his face4 ,instead of showing any aversion to the pile1 he readily obeyed whenever he was called to undergo the operation2 and his whole conduct indicated that he found relief from the influence of the unknown agent which it excited4 ,he began to converse with more readiness1 sometimes respecting the machine1 and sometimes on the flash of light which appeared in his eyes when the arc was applied2 and on that account we conceived the most flattering hopes of a complete cure4 ,the result of this operation induced me to administer the ,galvanism even to the substance of the brain2 being convinced1 as ,i have already remarked1 that the ,galvanic fluid by this method of application exercises its action with greater energy4 ,i communicated my design to the ,professors of the hospital1 and with their approbation began to try the effects of a pile composed of fifteen plates of copper and zinc4 ,i formed an arc from one of the hands to one of the ears1 and then from one ear to another1 having first moistened them with a solution of muriate of soda4 ,i increased the number of plates of which the pile was composed1 and found that the patient was always more or less affected with a momentary impression exceedingly painful1 which however seemed in the end to produce a good effect4 ,when ,galvanism was administered in this manner1 ,i did not neglect to continue the application of the other method at the same time2 and ,i found that the progress of the cure became more rapid4 ,but as ,i observed that the action of ,galvanism on the ears was sometimes too violent1 we thought proper to apply it in a more moderate and less dangerous manner4 ,several persons having been induced through curiosity to try this action1 the result1 besides a violent commotion of the whole substance of the brain against the skull1 was a state of watchfulness which continued several days running1 and which ,i experienced myself as well as others4 ,we then conceived the idea of shaving the head above the suture of the parietal bone 7,plate ,,iii4 fig4 #c472 and having moistened the shaven part with salt water1 a piece of gold or silver coin was placed over it4 ,the patient then touched with one of his hands the bottom of the pile1 and at the same time an arc was established from the summit of the pile to the metallic armature placed on the head4 ,by this arrangement the action of the ,galvanism was rendered more moderate2 the patient endured it for a long time1 and seemed to be greatly relieved by it4 ,i have always united this method with external application to different parts of the face1 and have observed such sudden changes in the looks as seemed to announce a considerable abatement of the disease4 ,some of the physicians of ,bologna1 ,professors ,brugnatelli and ,zola of ,pavia1 and several other foreigners1 examined and confirmed the permanency of this effect4 ,the patient1 therefore1 not only got the better of his melancholy1 but began to relish his food1 and at length recovered so much strength that the physicians of the hospital thought nothing further was necessary to complete the cure4 ,no other remedy besides ,galvanism was administered to him1 lest the effects should be so confounded as to render it impossible to tell to which the cure ought to be ascribed4 ,two days1 however1 before he left the hospital a little blood was taken from him2 as it was conceived that this operation might contribute to render the cure more certain4 ,on his leaving the hospital ,i carried him to my house1 that he might be fitted by proper nourishment for resuming his former occupations4 ,he remained with me eight days in the quality of a domestic1 during which time he was exceedingly tractable1 and performed his duty with great care and attention4 ,i had several conversations with him1 in the course of which ,i learned that his father1 ,fabian ,lanzarini1 had been attacked by the same disease1 and that he had been admitted into the same hospital1 where he died on the #abth of ,june #agij4 ,by inspecting the registers of the hospital1 ,i found this account to be perfectly correct4 ,agreeably to the principles already established1 in regard to the treatment of madness1 ,i advised ,lanzarini to spend the rest of his life at a distance from his native country1 lest1 having continually before his eyes those objects which had occasioned his disease1 it might recur with double violence4 ,but though he had given me several proofs of his docility1 ,i found it impossible to persuade him to make this sacrifice4 ,a kind of nostalgia1 perhaps1 attached him to his former master1 to whom he returned1 after paying a visit to the cur of the parish4 ,the latter1 when he first saw him1 imagined he had run away from the hospital2 but by his conversation he was soon convinced of his being completely cured4 ,after this period1 ,i obtained a regular report respecting his behaviour and the state of his health1 from the above cur1 and from the person who had paid all the expenses of his residence in the hospital2 and ,i learned1 with great satisfaction1 that he continued to enjoy good health1 and to exercise his usual employment4 ,by the same treatment ,i cured1 of a similar disorder1 ,charles ,bellini1 a labourer1 who was restored to society in a shorter space of time1 because the affection was not so violent as in the preceding case4 ,the phnomena which took place when the patient was subjected to the action of the pile1 when the ,galvanism was applied to the brain1 and during the whole progress of the cure1 were nearly the same4 ,i must1 however1 freely acknowledge1 that two cures are not sufficient to establish the application of ,galvanism as an universal remedy in such cases4 ,but on this account it ought not to be rejected3 at any rate it deserves further examination2 for it is well known that all remedies require certain conditions before they can perform their effect4 ,i have therefore several times found it impossible to obtain the same result in other patients afflicted with melancholy madness1 to whom ,i administered ,galvanism2 and in cases of raving madness ,i have even found it dangerous4 ,in some instances1 melancholy madness derives its origin from a certain general constitution of the animal machine1 or from some great alteration in the brain2 and it is evident that in such cases the action of ,galvanism would be of no avail4 ,but if the derangement of the intellectual functions depend only on some humour intercepted between the membranes and other parts of the brain1 there is reason to hope that ,galvanism1 if prudently administered1 may be attended with great benefit4 ,the real cases in which it may be administered with success1 can be ascertained only by experience4 ,i must observe also1 that the method of administering it is not yet reduced to that state of simplicity1 which is necessary before it can be brought into regular use in large hospitals4 ,the physicians1 under whose care they are placed1 have in general a great deal of private practice1 and cannot conveniently attend to operations which require a continued labour for several months4 ,besides1 the novelty of the remedy is sufficient to excite a clamour against it1 and to awaken the prejudice of the assistants1 who will even wish to proscribe it before it has been tried4 ,for this reason1 ,i think it necessary here to request1 that those who preside over establishments destined for the reception of such patients would turn their attention to this subject1 and endeavour to reduce the method of applying ,galvanism to the utmost simplicity of which it is susceptible1 in order that it may be fit for being introduced into large hospitals4 ,as the patient often shows an aversion to this strange remedy1 it will be necessary to encourage him by every means possible4 ,sometimes on observing the flash of light1 when the ,galvanism is communicated1 he cries out and is frightened2 imagining that he sees a devouring fire ready to consume him1 and on this account refuses to submit again to the operation4 ,it will1 therefore1 be proper to conceal from him the apparatus1 or to make a person show him the pile some time before as an object of amusement1 and in this manner to prepare him for receiving its action4 ,it will be of benefit also sometimes to modify the action of the pile1 and to render it more moderate by a different method of application4 ,in the case of female patients ,i have found the result the same1 when the ,galvanism1 instead of being applied directly to the interior part of the ears1 was directed externally to the gold pendents 7,plate ,,iii4 fig4 #d474 ,by considering the course generally pursued in curing melancholy madness1 hints may be suggested for an useful application of ,galvanism in that disease1 and data may be obtained sufficient to establish the different modes of application best fitted to the different cases4 ,these ideas have engaged a good deal of my attention2 and when ,i have finished the observations ,i have been for some time collecting1 ,i flatter myself that ,i shall be able to communicate to the public some interesting information on the subject4 ,in some cases of madness1 as ,i found it impossible to apply ,galvanism to the hands1 which were confined1 ,i employed the action of an arc directed to the mouth 7,plate ,,iii4 fig4 #b471 while another proceeded to one of the ears2 or ,i applied a piece of money to the head1 and communicated the ,galvanism by the method already described 7,plate ,,iii4 fig4 #c474 ,it will even be necessary to try the effect of the ,galvanic current1 sometimes continued1 and sometimes interrupted by means of the apparatus employed for diseases of the organs of hearing4 ,it will be proper1 in many cases1 to combine moral with physical treatment1 and not to neglect the other methods already known and practised1 which may be used as very convenient auxiliaries4 ,,section ,v4 ,general reflections on the action and influence which ,galvanism1 considered in a medical point of view1 exercises on the animal conomy4 ,i shall not here speak of the variation in insensible perspiration1 and of the increase of circulation1 which1 according to the observations of several physicians1 are found to be produced by ,galvanism4 ,similar phnomena1 as is well known1 take place during the administration of common electricity4 ,i shall therefore confine myself to those effects which hitherto have been produced only by the action of ,galvanism4 ,i shall observe in the first place1 that ,galvanism1 as already shown in the ,experiments detailed in the ,second ,part1 is capable of effecting a separation of the fluids1 and even sometimes of protruding the fcal matters from the body4 ,in the case of the decapitated malefactor1 ,i found that when the arc was applied to one ear and to the lips1 a very sensible portion of saliva was discharged from the mouth4 ,this observation was confirmed at ,genoa on the head of an ox1 and in several other places on the heads of sheep4 ,the phnomenon of the extrusion of the fcal matters from the trunk of an ox1 by means of ,galvanism1 was observed also by ,professor ,mojon of ,genoa1 and his brother1 to take place in human bodies4 ,considering the animal fluids separately1 ,i have found that very great variations are produced in them by ,galvanism4 ,but before ,i give an account of the experiments which ,i made on this subject1 ,i shall describe the apparatus ,i employed4 ,the animal fluid destined to be exposed to the action of ,galvanism is put into a glass vessel 7,plate ,,iii4 fig4 #f47 covered by a wooden lid1 having in it two holes equally distant from the centre4 ,two wires1 one of brass and the other of plated copper1 the upper extremities of which are bent into the form of a hook1 pass through these holes in such a manner1 that the lower extremities of them reach nearly to the bottom of the vessel1 where they are bent at right angles1 so that only a very small interval is left between them4 ,the upper extremity of one is made to communicate with the bottom of the pile1 and the other with the summit4 ,in consequence of this arrangement the ,galvanic fluid is obliged to traverse the animal fluid1 by which means it exercises an action on it according to the distance of the wires1 and by its action separates from its different strata sometimes one principle and sometimes another2 and this secretion will be effected with more ease and in greater abundance1 according as the action of the pile is stronger1 and the capacity of the conductors more considerable4 ,,experiment ,i4 ,having put into glass vessels four ounces of blood recently drawn from the vein of a person in good health1 ,i left one of them exposed to the contact of the atmospheric air1 and subjected the other to the action of the pile4 ,in both these portions ,i observed a speedy coagulation of the crassamentum1 and at the end of twenty-four hours the serous part was separated4 ,the blood exposed to the action of the pile adhered so strongly to the two wires immersed in it1 that it was difficult to separate them from the clot which was thus suspended in the aqueous fluid1 but in the other vessel the clot remained at the bottom4 ,,experiment ,,ii4 ,i put two equal portions of bile1 still warm1 taken from the gall-bladder of an ox1 into two glass vessels1 exposed one of them to the contact of the air1 and subjected the other to the action of the pile4 ,after ten hours had elapsed1 ,i observed that the bile in the latter had become so opake as no longer to afford a passage to the light2 while the other portion1 exposed to the atmosphere1 retained its transparency and colour4 ,i observed also a considerable disengagement of air1 the nature of which ,i have not yet had an opportunity of examining4 ,,experiment ,,iii4 ,i took four ounces of urine1 voided by a man in good health1 exposed it to the action of the pile1 and at the end of twenty-four hours found that the greater part of its constituent principles was separated4 ,a portion of them was collected around the wires in such a manner as to form cylindric bodies of a considerable diameter1 of which the wires were the axes4 ,as the mass of the attracted matters increased1 a portion fell to the bottom by its own weight4 ,the cylinders were soon entirely destroyed1 and the substances which formed them were precipitated by the least shock given to the vessel4 ,i repeated this experiment lately in ,mr4 ,wilson's anatomical theatre in ,windmill-street2 and ,i observed1 at the end of eighteen hours1 a great quantity of the molecul furnished by the urine adhering to the two wires4 ,but at length1 not being able to withstand the effect of its gravitation1 it began to fall down1 forming a sort of wedge1 the apex of which was at the surface of the urine1 and the base at the bottom of the vessel4 ,,experiment ,,iv4 ,instead of putting the urine into a common apparatus1 if a glass syphon with two platina wires be employed 7,plate ,,iii4 fig4 #e471 the urine becomes limpid on the one side1 and turbid on the other4 ,the substance detached from the urine afterwards appears in the form of flakes1 which are attracted by the platina wires4 ,i observed this phnomenon for the first time in the company of those celebrated chemists ,fourcroy and ,vauquelin1 while they were performing ,galvanic experiments in their own laboratory4 ,,experiment ,v4 ,the substance above mentioned1 which was precipitated to the bottom1 when separated by filtration and dried1 weighed about the fourth of a grain1 and the fluid separated from it was of a greenish colour4 ,on examining the earthy deposit of this urine1 we obtained sulphate of lime by adding to it sulphuric acid4 ,,experiment ,,vi4 ,having exposed to the action of the pile1 in the same manner1 four ounces of urine voided by a person with jaundice1 ,i obtained an earthy sediment1 the weight of which was nearly equal to that above mentioned4 ,the liquor separated from it was transparent1 inclining a little to black4 ,by the same chemical process ,i obtained sulphate of lime1 though the sediment of the urine was somewhat dark1 and afforded a portion of carbon and bile which inflamed in the fire4 ,,experiment ,,vii4 ,having repeated the above experiments with different kinds of urine1 ,i observed in general1 that ,galvanism1 by a peculiar attraction1 separates from urine the sulphates and muriates united to a portion of the bile1 and also to carbon1 which in a great part are precipitated to the bottom of the vessel3 the other part1 which remains attached to the wires1 exhibits a regular saline crystallization1 of so singular a form that it seems worthy of becoming an object of further research to chemists4 ,the examination of urine voided by persons labouring under different kinds of disease1 seems to be an object sufficient to excite the curiosity of physicians4 ,to expose to the action of ,galvanism artificial ariform fluids1 analogous to those which act a part in the animal conomy1 might also be attended with advantage4 ,for this purpose it will be convenient to employ the apparatus represented in ,plate ,,iii4 fig4 #g1 which was lately constructed1 with great precision1 by ,m4 ,dumoutier at ,paris4 ,the whole artifice consists in a vertical metal tube1 which can be raised up or pushed down4 ,it is furnished with a stop-cock1 and the tub in which the apparatus is placed has another4 ,if the inverted bell be filled with water1 and connected1 by means of the vertical tube1 with the apparatus which is to supply the gas1 on opening the lower cock1 the water will descend in the bell1 and its place be supplied by the gas intended to be subjected to experiment4 ,from all the observations hitherto made1 there seems to be reason to conclude1 that the effects produced on the animal conomy by common electricity and by the ,galvanic pile are different4 ,the phnomena of artificial ,galvanism give us some right to suppose1 that a similar action is exercised by the ,galvanic fluid circulating in the fluids and in the organs of living animals4 ,in this point of view ,galvanic researches may one day throw great light on the nature of secretion2 and it may perhaps be found necessary1 when remedies are administered1 to take its influence into consideration3 for it is possible that the action of these remedies in the animal conomy may depend on the establishment of such an arc between the system of the nerves and that of the muscles1 as may not alter the natural state of the ,galvanic fluid proper for the constitution of the individual to whom these remedies are administered4 ,all this however is mere conjecture1 and must be classed with many other things in the theory of ,galvanism which are still involved in obscurity1 and which we can hope to see explained only by new researches and new experiments4 ,taking a general view of this ,third ,part1 ,i must observe that the administration of ,galvanism1 when the above experiments are carefully examined1 seems to appear in a much more advantageous point of view than before4 ,i have indeed proved3 #ast4 ,that ,galvanism1 on many occasions1 exercises an influence different from that of common electricity1 and that it may be administered in various cases with great ease and safety4 #b;d4 ,that the action of ,galvanism manifests itself by a sensible attraction between the nervous and muscular parts2 which seems to confirm the hypothesis of ,humboldt1 who supposes a ,galvanic atmosphere peculiar to these parts when in a state of perfect vitality4 #c;d4 ,that the strong impression made by ,galvanism on the brain seems to explain its power on the organ of hearing2 and therefore the physicians of ,berlin1 and other parts of ,germany1 are entitled to great praise for their researches on this subject4 #dth4 ,that though medicine is capable of affording considerable aid in cases of drowning and of asphyxia1 it presents us with no means so powerful as ,galvanism4 ,the experiments made at ,london1 ,jan4 #ag1 #ahjc1 on the body of ,forster1 executed for murder1 have fully convinced me of the activity of this stimulant4 #eth4 ,that in cases of melancholy madness1 when other remedies fail1 ,galvanism may be employed with the greatest hopes of success1 provided the disease does not proceed from a vitiated constitution1 or a general derangement in the animal machine4 #fth4 ,that the current of the ,galvanic fluid produces a great alteration in the animal fluids2 separates a great many of their principles1 and produces this effect in a particular manner in urine4 ,it is however much to be wished1 that in addition to the knowledge already acquired in regard to ,galvanism1 some convenient method could be discovered of increasing or lessening its action on the animal fluids2 by which means the advantages of the medical administration of this subtle agent would be rendered more certain and more effectual4 ,,dissertation ,,on ,,animal ,,electricity3 ,,read ,,in ,,the ,,institute ,,of ,,bologna1 ,,in ,,the ,,year #agic1c ,,by ,j4 ,,aldini4 ,i4 ,while our ,academy was congratulating itself on the progress made by the doctrine of animal electricity1 its exultation was in some measure checked by an objection brought against it1 which did not attack any one part of it1 but the whole theory4 ,if the contractions in animal bodies1 said its opponents1 are produced merely by the electricity of metals1 how degraded is that electricity which at first was supposed to reside in animal bodies1 since it is now found to be subservient to the electricity borrowed from metals6 ,i heard repeated objections of this kind while labouring under a severe indisposition2 but being restored to health by the skill and attention of ,galvani1 ,i took the earliest opportunity to inquire after the success of his animal electricity1 and at the same time promised him every assistance in my power in the prosecution of his researches1 for which ,i always entertained a great fondness4 ,he accepted my offer2 and as ,i had now recovered my former strength and vigour1 ,i was anxiously desirous to defend the cause of animal electricity1 attacked and almost exploded1 amidst a variety of contradictory opinions1 and with this view to undertake a new series of experiments4 ,,ii4 ,the theory of animal electricity had scarcely been proposed1 when a suspicion was entertained that it might be produced by some external agent excited by the arming or by the arc4 ,this suspicion ,galvani endeavoured to obviate in various ways4 ,by using an insulated arc1 it was impossible that the person who performed the experiment could communicate any of his electricity to the animals4 ,in preparing the frogs he employed no conducting bodies2 he neither touched them with his fingers nor with a knife2 he uncovered the muscles and nerves with idio-electric bodies1 and still the usual contractions took place4 ,nay1 ,galvani carried his attention so far as to exclude even the air4 ,having immersed a frog with an insulated arc in a glass vessel filled with oil1 and having made a communication by means of an arc between the muscles and nerves1 muscular contractions were immediately produced4 ,this electricity1 the animal being thus surrounded by idio-electric bodies1 could not certainly be furnished by the atmosphere1 from which it was entirely separated4 ,while engaged in these experiments1 the celebrated ,spallanzani stopped a few days at ,bologna on his way to ,pavia1 and during a short conversation which he had with ,galvani on his new system1 expressed some suspicion that the electricity observed in animals might be acquired from external bodies4 ,after some discussion however on this subject1 ,spallanzani acknowledged that the experiment made on the frog immersed in oil was so conclusive1 that nothing could be better calculated to satisfy all his doubts4 ,i mention this circumstance1 because the approbation of so eminent a man was of the utmost importance to the cause of the theory of animal electricity4 ,,iii4 ,having proposed the before-mentioned series of experiments1 ,i was led into various reflections on this subject4 ,as the same electricity exercises an extensive action in the different parts of animals--some becoming electric through an excess1 and others through a deficiency of it--,i could not comprehend why there should not be an electrical movement even when the end of a very long arc was covered by a non-conducting body2 and why the same arc touched by the same person1 in the same atmosphere1 should sometimes become charged with a very small quantity of electricity1 only capable of exciting motion in the legs of a frog1 and sometimes with a large quantity sufficient to produce contractions in the leg of a lamb or a calf4 ,this circumstance appeared to me to be involved in a considerable degree of obscurity4 ,i conjectured also that internal electricity might have been implanted in animal bodies for the purpose of defending the animal conomy1 and protecting it against any injury which it might sustain from an excess of the external atmospheric electricity4 ,were not this the case1 there might be reason to apprehend that the electricity of the clouds1 in the time of storms1 might attack the human body and destroy it4 ,,iv4 ,but though the suspicion of electricity being communicated from the air1 or from the person who performed the experiment1 was lessened or removed1 there were still some who thought that the objection in regard to metals could not be obviated in the same manner4 ,the idea generally entertained1 that all the contractions ascribed to animal electricity were to be ascribed only to external electricity1 proceeding from the armatures1 and not to any electric virtue in the animals1 seemed to be strengthened4 ,carradori1 who had made this objection1 afterwards altered his opinion1 and became a strenuous advocate for animal electricity2 but the celebrated ,volta still entertained great doubts4 ,these he communicated to me in a long letter1 and they were afterwards published in the ,pavian ,journals4 ,all his doubts were founded on this circumstance3 heterogeneous metals are required to produce contractions2 one of which becomes charged positively and the other negatively2 and it is only in the act of restoring an equilibrium between them that muscular contractions are excited4 ,v4 ,this simple and ingenious idea was no doubt highly captivating2 but the experiments made by ,galvani and by myself prevented me from adopting it entirely2 for it is evident from ,galvani's ,dissertation1 and from my own observations1 that if the muscles and nerves of a frog be immersed in two vessels filled with water1 contractions will be produced on the application of a metallic arc4 ,here then we have muscular contractions with one arc and with one metal4 ,living frogs subjected to the action of rarefied or of condensed air1 and afterwards dissected in the usual manner1 exhibit contractions without any armature1 and merely by a silver arc applied to the muscles and nerves2 and this is always the case1 whether the frogs be large and strong1 or small and weak4 ,while engaged with these experiments1 ,galvani informed our academy that he had obtained contractions in large and vigorous frogs1 which had been recently dissected1 without the help of the air pump and without armatures1 merely by the application of an arc4 ,the same thing occurred to ,carradori1 who1 though he at first entertained doubts on this subject1 was afterwards convinced of the truth of the phnomenon4 ,it still however appeared to me1 notwithstanding the results obtained by ,galvani and ,carradori1 that the animal electricity of frogs was excited in more abundance by the action of the air pump1 even without the application of armatures4 ,,vi4 ,but that the series of experiments ,i had undertaken might be better calculated to establish the theory of animal electricity1 and as it was difficult to find any of the solid metals homogeneous throughout1 ,i had recourse to mercury1 which1 by the help of chemistry1 may be brought to a very considerable degree of purity4 ,for the greater convenience in the employment of this substance1 ,i invented the following apparatus3--,two glass vessels are so arranged 7,plate ,,iv4 fig4 #a47 that the one stands above the other3 the upper one is filled with mercury1 and the spinal marrow of a prepared frog is placed in it2 and by means of a hole in the bottom of it1 which may be opened at pleasure1 the mercury can be made to fall on any part of the muscles of the same animal placed in the lower vessel4 ,the stream of mercury occasions convulsive movements to take place in the muscles2 and yet in this case the mercury forms both the armature and the arc3 consequently the electricity in both is the same1 and can exercise no action4 ,when contractions therefore take place1 they cannot be ascribed to the electricity of the metal4 ,should it be said that the mercury as it runs down may excite electricity from the sides of the glass vessel1 as is the case with the mercury in the upper part of a barometer1 which1 when in the least agitated1 shines with an electric light1 any doubt on this subject may be easily removed by substituting vessels of wood instead of those of glass4 ,,vii4 ,when these vessels are used1 care must be taken to pay attention to one circumstance1 which may prevent the success of the experiment4 ,as the spinal marrow is exceedingly light1 it will float on the surface of the mercury2 whereas it ought to be immersed in that metal4 ,it will be necessary therefore to press down the spinal marrow below the surface of the mercury1 by means of a glass rod1 or any other non-conducting body1 so that it may be entirely immersed2 otherwise some irregularity may take place1 and the experiment fail4 ,to perform it with the greatest convenience1 provide a glass vessel consisting of two branches in the form of a syphon1 as represented in ,plate ,,iv4 fig4 #b41 one of which is wide1 and has its edges reflected inwards1 so as to form an inverted cone1 ending in an aperture that can be opened and shut at pleasure4 ,if mercury be poured into the narrower branch1 so as to fill the interior part of the vessel around the inverted cone1 it will not be able to rise up into the latter1 until the aperture in its apex be opened4 ,when this arrangement has been made1 immerse the spinal marrow of a frog in the mercury contained in the smaller branch of the vessel1 and place the muscles in the conical part1 which is empty3 if the aperture be then opened1 the mercury1 endeavouring to bring itself into a state of equilibrium1 will come in contact with the muscles1 and contractions will be produced2 as an arc of quicksilver will thus be speedily formed between the nerves and the muscles4 ,,viii4 ,but the experiment may be performed in a manner still more simple4 ,provide a glass vessel 7,plate ,,iv4 fig4 #aj47 filled with mercury1 and let the muscles of a prepared frog be laid to float on the surface of the metal2 then suspend the spinal marrow by a silk thread in such a manner1 that by letting down the thread the marrow can be made to touch the mercury at pleasure4 ,as soon as the spinal marrow is brought into contact with the surface of the metal1 contractions will take place in the muscles2 and the same will be observed if a plate of gold or silver be substituted in the room of the mercury4 ,this phnomenon will be exhibited not only by a whole frog1 but by half a frog divided longitudinally2 which1 as soon as it touches the mercury1 by the method above described1 will be violently convulsed4 ,having mentioned these experiments to ,galvani1 to whom ,i often had recourse for instructions1 he regretted that ,i had confined my researches to frogs only1 and advised me to try warm-blooded animals4 ,i therefore took the leg of a lamb or a chicken1 and holding it in my hand in a vertical position1 in such a manner that the bare muscles were in communication with the mercury1 ,i then raised the crural nerve without any armature1 so that1 by being left to itself1 it could be made to touch the mercury at pleasure4 ,as soon as it did so1 ,i observed a violent agitation and contraction in the whole limb1 and likewise when ,i used the before described apparatus1 ,plate ,,iv4 fig4 #b4 ,,ix4 ,while ,i made these experiments1 ,i was well aware that the contractions produced in the limb might by some be ascribed to the impulse of the mercury1 acting on it like a kind of stimulus1 or to electricity received from the surrounding bodies1 rather than to the innate electricity of animals4 ,i would advise those who entertain such an opinion to hold the hind legs of a frog in their hand1 in a vertical position1 and to press only the spinal marrow against the surface of the mercury4 ,let them immerse also the spinal marrow in salt water1 or in vinegar3 no contraction will take place1 though in this case there is still a mechanical impulse2 and though the saline or acid quality of these liquids is exceedingly proper for acting as a stimulus4 ,to this ,i may add1 that in the apparatus already described 7,plate ,,iv4 fig4 #b47 there is no impulse from the mercury1 which acquires only that gentle motion necessary to enable it to put itself into a state of equilibrium4 ,in a word1 ,i have observed 7,plate ,,iv4 fig4 #a47 that when both the upper and lower vessels are filled with mercury1 if the aperture be opened so that the metal which falls down shall not strike against the muscles2 yet the same contractions take place3 which indeed ought to serve as a proof that mechanical impulse has no share in producing the effect4 ,x4 ,but ,i had no reason to apprehend the action of any stimulus1 as ,i had before found by experience1 that a very strong impulse applied to the nerves or to the muscles excited no contractions4 ,i made experiments for this purpose1 not on living but on dead animals1 when the irritability was feeble and almost extinct2 and ,i found that it could be excited neither by pricking with a needle1 by acids1 nor by the most powerful stimulants4 ,it seemed to be entirely dead2 but ,i observed both in cold and in warm-blooded animals1 provided the experiment was performed within a certain period1 that the irritability was always obedient to the power of the ,galvanic arc1 though no effect was produced by any mechanical impulse4 ,as frogs were most convenient for my experiments1 ,i tried them with every possible kind of mechanical stimulants4 ,i immersed the spinal marrow or the nerves in acids2 pierced them with a needle2 cut the nerves1 and even sometimes scooped out the whole medullary substance from the vertebral canal2 still no motion was produced4 ,but the same nerves and muscles which had withstood such powerful mechanical stimulants1 when metallic armatures and an arc were applied in the gentlest manner1 immediately exhibited contractions4 ,,xi4 ,having obviated every objection that might be made in regard to the action of stimulants1 ,i shall now endeavour to remove any doubt that may remain of external electricity4 ,provide a glass cylinder terminating in a neck1 and introduce into it a prepared frog with a little mercury2 incline the cylinder in such a manner1 that the mercury may occupy the lower part of it1 and form an armature to the muscles4 ,if the extremity of the neck of the cylinder be applied to an enameller's lamp1 and sealed hermetically1 all communication between the inclosed frog and the external air will be cut off4 ,now1 if the cylinder be removed from its inclined to a horizontal position1 the mercury1 which was in contact only with the muscles1 must touch also the spinal marrow2 and a mercurial arc being thus formed1 contractions will immediately follow4 ,if the experiment be repeated with the glass cylinder immersed in oil1 the same contractions will take place2 but in this case it will be necessary to remove the immersed cylinder a little from its position by means of a silk thread1 in order that you may be enabled to make the mercury flow from the nerves to the muscles at pleasure4 ,,xii4 ,there is no reason1 therefore1 in this case1 for ascribing the contractions either to the arc or to the armatures1 which1 as they consist of mercury alone1 cannot produce the two kinds of electricity necessary for exciting contractions4 ,but even if we should allow1 with those who form the most absurd suppositions1 that mercury alone possesses both kinds of electricity1 one contraction only could be expected1 and not several in succession4 ,in a word1 there is no reason to apprehend that any external electricity is obtained either from the glass vessel which receives the mercury1 or from the surrounding atmosphere1 which is separated from the spinal marrow by three strata of non-conducting bodies2 namely1 air1 glass1 and oil4 ,the simplicity of this process may not be fully apparent to the reader2 but ,i can with truth assert1 that simplicity was an object which ,i had always in view4 ,having prepared a frog1 ,i laid it to float in mercury immersed in oil1 and then endeavoured to excite contractions by the application of an insulated arc4 ,owing to some inaccuracy in the experiment1 however1 it did not succeed2 and my attachment to simplicity1 while endeavouring to discover the least complex method of exciting contractions1 was the cause of my not obtaining the desired result4 ,this want of success was perhaps owing to the mercury not being in proper contact with the nerves1 in consequence of the oil adhering to them4 ,that ,i might exclude all suspicion of atmospheric air having any share in the phnomenon1 ,i was obliged to adopt that method of performing the experiment which ,i have already described4 ,,xiii4 ,i however readily foresaw1 that the advocates of external metallic electricity might object1 that no contractions were obtained but by the application of armatures1 or1 when armatures were excluded1 by using in their stead an arc1 which is itself an armature4 ,and ,i must indeed acknowledge that we are as yet acquainted with no substances but metals capable of exciting animal electricity1 though nature1 so abundant in resources1 may no doubt furnish a great many#d4 ,but ,i shall here observe that metals are not the cause of the contractions produced in animal bodies1 but merely a condition requisite for calling forth the latent innate animal electricity which exists in them4 ,for though armatures are necessary to render non-conducting bodies electric1 there is no reason why the shock given by the ,leyden flask should be ascribed to the arc or to the armatures2 as a charged magic square1 or a ,leyden flask1 when freed from the armatures1 exhibits a great quantity of electricity4 ,if you charge a ,leyden flask filled with water1 pour the water from it1 then pour in other water1 and form a communication by an arc between the opposite surfaces1 you will experience a shock4 ,this very simple experiment agrees with some made by ,mr4 ,wilson1 ,mr4 ,cavallo1 and others4 ,armatures1 therefore1 have a powerful effect in attracting electricity1 and confining it in non-conducting bodies2 but they do not supply electricity themselves4 ,,xiv4 ,if this mode of reasoning be admitted in regard to common electricity1 it ought not to be rejected when applied to the phnomena of animal electricity4 ,for1 as an explosion is produced by a magic square1 or ,leyden flask1 even when the armatures are removed1 the case is the same in regard to the contractions in animals4 ,but to prove in a more evident manner that metals have no action in such cases1 the following experiment was made4 ,an insulated person1 holding in his hand a metallic arc1 and a prepared frog1 furnished with heterogeneous armatures1 was electrified1 as well as every thing about him1 by means of an electrical machine4 ,the person1 the frog1 the armatures1 and the arc1 being all electrified positively1 none of the metals employed in this experiment1 as their electricity was reduced to a state of equilibrium1 could produce contractions4 ,as these are produced only by applying the arc to the armatures1 they cannot be ascribed to external electricity1 but to the innate electricity of the frog4 ,if only one of the armatures be touched1 no contractions take place2 but if the arc be applied to both1 they are immediately produced2 which is a strong proof that the arc possesses the power of exciting the electricity inherent in animal bodies4 ,those philosophers would reason very incongruously who should ascribe the cause of these contractions to electricity communicated from the person1 since they would thus allow to the person that animal electricity which they deny to the frog2 a conclusion which few will admit4 ,but in attempting to remove every suspicion of communicated electricity1 it was necessary that the experiments undertaken should be free from all influence of artificial electricity4 ,,xv4 ,i therefore endeavoured to obtain an equilibrium in the armatures by mutual contact4 ,this simple method was borrowed from the principles adopted by philosophers1 who1 while they endeavour to produce an equilibrium1 are accustomed to apply a body electric by excess to one in a contrary state4 ,immerse in water the spinal marrow of a prepared frog1 without armature1 and let the muscles rest on a non-conducting body4 ,the vessel must be somewhat in the form of a syphon1 and the spinal marrow introduced into the smaller branch must not float on the liquid1 but be totally immersed in it3 this arrangement is of great importance in regard to the success of the experiment3 a small piece of tin foil must be made to float on the surface of the water at a considerable distance from the spinal marrow3 if you then touch the muscles with one of your hands moistened a little with water1 and with the other apply a silver arc to the tin foil1 a contraction will immediately take place4 ,while struck with the constancy of this phnomenon1 ,i could not help reasoning in the following manner3 ,muscular motion is produced though the frog is in contact with no metallic body3 every thing metallic is separated from the frog2 and even if it possessed contrary kinds of electricity1 they are in a state of equilibrium4 ,what then is the external agent which produces contractions in the frog8 ,though the metals1 while they acquire an equilibrium1 come into contact1 which is followed by contractions1 there certainly can be no fear of external electricity from them4 ,this is sufficiently proved by the metals themselves being brought into equilibrium before the contractions take place4 ,if you touch the muscles with one hand moistened with water1 and with the other immerse into water a piece of gold coin1 a small part of which is covered with tin foil1 contractions will immediately ensue4 ,yet both the metals1 before the contraction1 were brought to a state of equilibrium by being in contact3 they can therefore have no share in the contractions1 which must arise from innate electricity4 ,if salt water1 milk1 serum1 or the crassamentum of the blood1 be substituted for common water1 there will still be contractions2 and the case will be the same if a bit of gold1 silver1 or brass1 or even iron1 covered with tin foil be employed4 ,here then we have tin brought into a state of equilibrium with various metals before the contractions take place1 without these contractions being impeded4 ,nor is it of any consequence that the metals be touched with the hand4 ,for1 if the tin foil be applied to the tip of the tongue1 or to the lips1 and if a piece of silver wire be made to touch the tin foil on the one side1 and the spinal marrow covered by no metal on the other1 contractions will be produced as often as an arc is made to the muscles by means of the moistened hand4 ,,xvi4 ,the object of our researches hitherto has been muscular motion2 we shall now direct them to the phnomena of the senses4 ,let an insulated person be electrified by means of a common electrical machine1 and let him apply a silver arc to the tip of his tongue covered with tin foil4 ,the armature and the arc will both become electrified by this new accession of electric matter4 ,we cannot therefore suppose one armature to be positively and the other negatively so2 and for this reason no transmission of electricity1 and no sensation of taste1 can be expected4 ,as the tongue1 however1 experiences a sensation of acidity1 it must have been excited not by the armatures or by the arc1 but by the innate electricity of the muscles and nerves4 ,but the necessity of an internal arc1 which appears in the above phnomena1 is an argument in favour of innate electricity4 ,in order1 however1 to excite the taste by animal electricity1 the application of different metals to the tongue is not sufficient3 the arc must be conveyed to the muscles of the tongue1 or to others at a distance from it4 ,when ,i first made this experiment1 it gave me no small pleasure to find that it was confirmed and enriched with new observations by the celebrated ,volta#e4 ,,xvii4 ,that the phnomena already mentioned arise from an interior arc1 will be proved1 in my opinion1 by the following experiment3 ,if an insulated metallic arc1 or a piece of charcoal1 be applied to the tip of the tongue with the moistened hand1 no taste will be produced2 but if the same hand be applied to the same metallic arc or charcoal1 a taste will be experienced4 ,in both cases of this experiment dissimilar armatures were brought into contact1 and reduced to that state of equilibrium to which they tended4 ,why then should the result of the experiment be so different8 ,when the metals or charcoal touch the moistened hand1 a speedy and uninterrupted communication is formed even between the remote muscles and the nerves of the tongue1 which when intercepted by the non-conducting body prevents all sensation of taste4 ,it may therefore be established as a principle1 that to excite a sensation of taste1 it is necessary besides the application of external armatures to have an internal arc1 which may bring the internal electricity to a state of equilibrium4 ,this observation is confirmed by ,carradori1 who1 while endeavouring to excite a sensation of taste in two persons at the same time1 found that it was necessary to establish an arc between them1 either by making them join hands1 or by moistening the plane on which they stood#f4 ,,xviii4 ,i shall conclude this dissertation with an account of some later experiments on this subject4 ,volta1 in a letter which ,i received from him1 requested ,i would try to produce contractions without any metallic application1 and recommended charcoal1 which in his first experiments he had found to be the best armature for animal electricity4 ,i therefore took the earliest opportunity of attempting to produce contractions in the beforementioned manner without the aid of metals4 ,i was encouraged in this design by ,aloysius ,laghi1 professor of chemistry2 who having analysed our fossil coal in consequence of a public decree for that purpose1 was desirous that chemical processes might be made subservient to my researches4 ,it was well known1 that every kind of vegetable charcoal formed the best armature1 so that when this coal was used there was no need for metallic armatures4 ,hence1 in that ,galvanic experiment called the animal alarum1 a charcoal plane substituted for one of silver produced the same effect3 charcoal arcs also were used instead of metallic4 ,the coal employed in this manner was vegetable coal3 but the ,english fossil coal1 and that dug up in our territories1 did not produce the same effect4 ,i employed the different principles extracted from our fossil coal1 namely1 calcareous earth saturated with the acetous acid1 siliceous earth semi-vitrified by fixed alkali1 and argillaceous earth4 ,all these1 however1 formed bad armatures for animal electricity2 and the case was the same with the ashes of our fossil coal1 and of the ,english coal4 ,,xix4 ,none of these phnomena1 however1 afforded any grounds for objecting against the theory of electricity in general2 as that bituminous substance which is always found combined with fossil coal1 deprives it of the power of being a conductor of animal electricity4 ,this conjecture was confirmed by experience2 for1 having employed our own fossil coal and the ,english in the state of coke1 they formed excellent armatures1 as by the action of the fire they had been freed from those idio-electric principles which opposed the development of animal electricity1 ,a phnomenon in the mean time occurred1 which tended to throw great light on the nature of this electricity4 ,having placed the spinal marrow upon a piece of coke1 and formed an arc from the muscles to the coke1 contractions always took place in certain parts1 while in others there was no appearance of them4 ,the reason of this seemed to be1 that the action of the fire had made some parts of the same coal conductors1 and left others idio-electric1 in consequence of the large quantity of the bituminous principle which they contained4 ,but though torrified fossil coal acquired a conducting property1 vegetable charcoal was still found to be much fitter for conveying animal electricity4 ,hence ,i conceived a hope1 that ,i should be able to excite contractions1 in the manner before described1 without any metallic arc1 and by the application of charcoal alone4 ,for these new experiments1 ,i employed the largest frogs1 and ,i selected on purpose such pieces of charcoal as seemed the least fitted for being conductors of animal electricity4 ,i placed the prepared muscles of a frog on the charcoal1 and suspended the unarmed spinal marrow1 by a silk thread1 in such a manner that the marrow could be made to touch the charcoal at pleasure4 ,when large frogs were employed1 contractions always took place2 and ,galvani found the case to be same in his experiments4 ,here then we have contractions produced without the intervention of any metallic substances3 why then ascribe to the different power of metals1 effects which can be produced by bodies which certainly have nothing of the metallic quality8 ,if the spinal marrow or muscles be made to communicate separately with the charcoal1 there will be no contraction2 and it appears that to produce contractions1 the arc and the armature must consist of homogeneous charcoal4 ,having given an account of my experiments1 it remains that ,i should collect in a few words the inferences which may be deduced from them4 ,,xx4 ,in the first place1 it is certain that to produce contractions it is not necessary to employ two different kinds of metal1 and that one is sufficient4 ,in vigorous animals this result may be obtained by silver1 and particularly by gold4 #b;d4 ,if any suspicion of heterogeneity should arise1 in regard to the solid metals1 this difficulty may be easily obviated by employing a fluid metal1 that is to say1 mercury purified by chemical means4 #c;d4 ,contractions are excited when one of the armatures and the arc consist of mercury1 by making the mercury to run down on the muscles placed below it4 ,there is no reason here to suspect that the stimulus produced by the impulse of the mercury has any share in the phnomenon1 as it is sufficiently proved by experiments that this is not the case4 #dth4 ,that when there is no reason to suppose a want of equilibrium in the electricity of the armatures and of the arc1 animal electricity is excited1 and produces contractions4 #eth4 ,that when the armatures and arc are formed of charcoal1 the same results will be obtained2 which evidently proves that the animal electricity is not produced by the metals4 #c ,the title of the work from which this and the following dissertation are translated is1 ,joannis ,aldini de ,animali ,electricitate ,dissertationes du4 ,bononi #agid4 #d ,there seems here to be some mistake1 as the author says1 towards the end of this ,dissertation1 that he produced contractions in a frog by employing coals1 both as an arc and as armature4 ,t4 #e ,the celebrated ,volta1 in a letter which ,i received from him1 announcing that he had observed the same phnomena as those described in my ,dissertation1 published the preceding year1 xxii4 p4 #ai4 added the following remarks3 8,the best and easiest method of performing this experiment1 is to immerse in a large earthen or glass vessel1 filled with water1 a silver dish1 in such a manner that a part of it remains above the surface of the water2 to apply to the tip of the tongue a small bit of tin foil1 so that part of it shall hang out of the mouth2 to bring this tin foil into contact with the silver vessel1 either immediately or by means of a third piece of metal2 lastly1 to immerse the hand in the same water gradually1 if you are desirous of perceiving gradually on the tongue the acid taste2 or suddenly1 and at once1 if you are desirous of perceiving it at once and in the highest degree4 ,a silver spoon half immersed in the water1 or instead of the dish1 if not too small1 will produce nearly the same effect as ,i have already mentioned4 ,the case is not the same with a slender silver rod or wire1 which if gradually immersed will scarcely produce any taste at all4 ,if the vessel which contains the water be itself of silver1 a dish or spoon will then be unnecessary4 ,this vessel forms the best armature for the water2 and to perceive the taste very strongly1 it will be sufficient to immerse the hand in the water1 or to bring the tin foil which hangs from the mouth into contact with the vessel4 #f ,as convulsions are excited in two frogs1 when one end of an arc is made to touch the uncovered crural nerves of the one1 while the other end of the arc is applied to the crural nerves of the other1 covered by an armature2 ,i have observed that the sensation of two tastes1 one acid and the other alkaline1 can be excited at the same time in the tongues of two persons1 one of which is armed with tin foil1 and the other with silver1 if a communication be formed between the two armatures4 ,it is necessary1 however1 that a communication also should exist between the two persons4 ,if the floor on which they stand be wet1 and their shoes moist1 this will be sufficient4 ,sig4 ,dottore ,giovachino ,carradori ,lettera quinta sull ,ellettricit ,animale1 diretta al ,chiarissimo ,sig4 ,cav4 ,felice ,fontana4 ,,second ,,dissertation ,,on ,,animal ,,electricity3 ,,read ,,in ,,the ,,institute ,,of ,,bologna1 ,,in ,,the ,,year #agid1 ,by ,j4 ,,aldini4 ,i4 ,the philosophers of the present period are so sanguine in their expectations1 that when a new theory is proposed1 unless it be presented to them perfect and fully proved1 they either attack it in part1 or entirely reject it4 ,such has been the case with animal electricity1 discovered by ,galvani4 ,it is urged against it by its opponents1 that it is subject to variations2 and because they do not find it obedient to all those laws established by the laborious researches of a ,franklin1 a ,beccaria and an pinus1 they assert either that it has no foundation1 or that it is contrary to nature4 ,it has therefore been conceived that an accurate comparison of animal and common electricity1 in order to ascertain whether there be any difference between them1 might be the best means of obviating such objections4 ,for this purpose ,i made various experiments in animal electricity under the air pump1 employing proper conductors1 and ,i compared its phnomena with those exhibited by the ,leyden flask4 ,in a word1 while ,i endeavoured to pursue my researches agreeably to the general theory of common electricity1 my principal object was to prove the constancy of animal electricity1 by discovering1 if possible1 an agreement in the physical laws of both4 ,,ii4 ,as it had been proved by a great many experiments1 that common electricity could be obtained from non-conducting bodies in the most perfect vacuum possible to be formed by means of an air pump1 experiments were undertaken in order to ascertain whether the same phnomenon was common also to animal electricity1 and with this view attempts were made to excite the latter in vacuo#g4 ,muscati indeed had deprived animals of life in vacuo1 and afterwards found them susceptible of ,galvanism in the open air2 but he made no attempt to determine whether the animal electricity could be manifested in vacuo4 ,i employed for my experiments a glass vessel2 ,plate ,,iv4 fig4 #f41 furnished with a metallic rod1 which could be1 raised up or pushed down at pleasure4 ,to the extremity of the rod1 within the receiver1 was affixed at right angles a metallic wire1 from one end of which an armed frog was suspended by the muscles1 and from the other a small metallic chain a little longer than the frog1 a plate of silver being placed below both the frog and the chain4 ,when as perfect a vacuum as possible had been obtained1 the metallic rod was pushed down1 so that the small chain and the spinal marrow of the suspended frog were made to touch the silver plate1 and by these means the latter formed an arc in the exhausted receiver4 ,in this experiment1 the power of ,galvanism was found to be the same as in the open air1 so that as often as the rod was pushed down contractions were excited in the frog4 ,by this method it was easy to ascertain what repeated contact could produce by forming new arcs3 for though the small chain and the extremity of the spinal marrow touched the silver plate2 yet1 when removed from that position ever so little1 by moving the rod new contractions took place1 which could not have been expected unless new contact on moving the rod had produced as it were new arcs4 ,this kind of apparatus seemed the most convenient for performing in vacuo all those experiments which ,galvani had performed in the open air4 ,,iii4 ,but it was as yet difficult to determine1 whether the contractions which took place were stronger in rarefied than in common air2 for the difference between the electricity was so small1 that it was impossible to say which was the more powerful4 ,i therefore resolved to clear up this point by other experiments4 ,for this purpose1 having cut in two a prepared frog1 ,i placed in vacuo one part of it1 by means of the above apparatus1 and after a short period drew it out1 and compared it with the half which had not been subjected to the action of a vacuum4 ,on applying an arc1 the one exhibited strong and the other faint contractions2 from which it appeared that the vacuum had occasioned some loss of the animal electricity2 as the muscular and nervous parts subjected to experiment belonged to the same frog1 this evidently showed that the whole difference arose from the action of the vacuum4 ,,iv4 ,it is well known that a vacuum absorbs common electricity2 and therefore it need not excite any wonder that in the present experiment it should have dispersed some of the animal electricity4 ,as this loss took place by insensible degrees1 strong contractions were not to be expected2 and the case is nearly the same in a ,leyden flask loaded with aqueous vapours1 which produces no remarkable explosion4 ,but though convinced of the truth of this circumstance1 ,i resolved to confirm it by a new experiment4 ,i therefore charged two ,leyden flasks armed in the same manner1 applying them at the same time to the same conductor1 and by the same number of turns of the machine4 ,one of these flasks was introduced into the glass receiver of the air-pump1 and the other was exposed to the atmosphere4 ,at the end of five minutes after the air had been exhausted as much as possible1 the flask in the receiver was taken out1 and1 being discharged by a metallic arc1 emitted a weak spark1 while the other flask exhibited strong signs of electricity4 ,i again charged two flasks by the same turns of the machine till the electrometer indicated in both the same degree of electricity1 and kept one of them for half an hour beneath the receiver4 ,when the latter was taken out1 it afforded a weak and almost exhausted spark2 while the other1 which had remained in the open air1 emitted a strong one4 ,had the first flask remained longer under the receiver1 it would no doubt have entirely lost its electricity2 while the other without the machine retained that with which it was charged4 ,v4 ,in this experiment every possible care was taken to observe the variations produced by the vacuum4 ,the receiver which covered the ,leyden flask was of a large size1 and the flask1 being placed in the middle of it1 was at a considerable distance from its sides3 the receiver was well fitted to the plate of the machine1 and not by means of moist leather1 as is usual1 so that all communication with the external air was prevented2 and therefore there is no reason to suppose that any aqueous vapour introduced into the machine1 when the pressure of the air was withdrawn1 could perform the office of an arc4 ,that the electricity might not immediately bring itself to a state of equilibrium1 the conductor of each flask terminated in a ball3 had not this been the case1 the whole electricity would soon have been dispersed2 for1 when the conductors terminate in a point1 if the chamber be darkened1 coruscations of light will every where be seen on the glass receiver1 and afford a most agreeable spectacle4 ,a conductor terminating in a ball seemed therefore to be most convenient for my purpose1 that1 by rendering it more difficult for the electricity to bring itself to an equilibrium1 ,i might be able to produce a greater imitation of the intimate manner in which animal electricity adheres to the animals4 ,but though in the above experiments ,i ascribe some part of the phnomena to the animal electricity being weakened in vacuo1 ,i am of opinion that more is to be ascribed to the violent perturbation of the principles which the vacuum must have excited in the muscular and nervous parts4 ,,vi4 ,as it was now established1 that animal electricity could be excited in vacuo1 ,i endeavoured to ascertain whether that excited without the vacuum1 and conveyed to the receiver1 could be made to pass through a very small space in vacuo4 ,for this purpose ,i placed the metallic rod at a small distance from a silver plate resting on the bottom of the air pump3 the limbs of a chicken or lamb1 prepared in the usual manner1 were then deposited near it2 and the muscles1 by means of a metallic chain1 were made to communicate with the plate of the machine1 while an armed nerve was made to communicate by means of an insulated arc with the metallic rod4 ,the air being exhausted1 the rod was pushed down1 and gradually brought as near as possible to the plate without coming into actual contact with it4 ,in this state no contractions were produced2 but they immediately took place when the rod was brought into contact with the plate4 ,it appears therefore that animal electricity is considerably impeded in its progress by a vacuum2 and that1 like artificial electricity1 it does not readily suffer itself to be dissipated1 unless transmitted through good conducting bodies4 ,for1 when a small quantity of the electric fluid is accumulated in the ,leyden flask1 either none of it proceeds from the metallic wire to a less perfect conductor1 or1 if any is transmitted1 it must be with difficulty1 and with great violence4 ,common electricity1 indeed1 is seen to pass quietly through metals or water separately2 but a strong electric spark1 in proceeding from one metallic conductor to another1 if it pass through water interposed between them1 does so with such violence1 that the glass vessel which contains the water is in danger of being broken to pieces4 ,that electricity1 therefore1 may be conveyed from a conducting body1 to one less endowed with that property1 it must be in such abundance as to be able to overcome the resistance of the body through which it has to pass3 hence1 it need excite no surprise1 that the small quantity of electricity which produces contractions should not be able to pass over a very small space in vacuo4 ,here then we have a proof that animal electricity is not only subject to the laws of non-conducting bodies1 but that it is affected different ways by the smallest obstacles of conducting bodies1 and by different kinds of them4 ,it is indeed so evident that a vacuum from its nature is unfit for conveying electricity1 that1 even if one be produced1 not by the usual method1 which is always attended with some defects1 but in the most accurate manner possible1 it is totally improper for being a conductor of the electric fluid4 ,this is sufficiently proved by the following experiment of ,walsh3 ,if two barometers be joined1 and the upper part or bend be carefully deprived of air1 when one of these barometers is electrified1 the electric fluid will not be communicated to the other1 in consequence of the resistance opposed by the intervening vacuum4 ,adams1 however1 exhibited by means of a single barometer the same phnomenon as ,walsh did with a double one#h2 for1 having extracted the air entirely from the upper part of the barometer1 no electric light was observed2 but on introducing a very small quantity of air the whole barometer became luminous4 ,these observations are sufficient to show that animal electricity1 in regard to the property of not being able to pass through a small space in vacuo1 is subservient to the general laws of common electricity4 ,but let us proceed to other phnomena respecting animal electricity excited in vacuo4 ,,vii4 ,if a prepared frog1 furnished with two armatures1 be placed in a horizontal position on a non-conducting body1 under a glass receiver1 7,plate ,,iv4 fig4 #aa47 and if an arc be formed by pushing down a rod1 so as to join both the armatures without touching the frog1 contractions will immediately take place2 but if the smallest non-conducting body intervene1 none will be produced4 ,i found it no very difficult matter to exhibit in vacuo1 by an apparatus somewhat similar1 what may be called an animal alarum4 ,a horizontal arm fixed to a vertical moveable rod 7,plate ,,iv4 fig4 #e47 was adapted to the inside of a glass receiver1 in such a manner that1 when the receiver was exhausted1 any body resting on the horizontal arm could be made to fall down4 ,the leg of a prepared frog was then fixed to the vertical rod2 while the other rested on the horizontal arm1 and the spinal marrow1 with an armature of tin foil1 touched a silver plate in the bottom of the receiver4 ,the horizontal arm being turned round a little1 by means of the vertical rod1 the leg of the frog resting on the arm fell down on the plate below3 an arc being thus formed1 contractions immediately took place1 and were incessantly repeated1 until all the animal electricity was restored to an equilibrium4 ,,viii4 ,these experiments were made on dead frogs2 but ,i shall here show that living ones also may be made to exhibit signs of electricity under the same circumstances4 ,a piece of tin foil was applied to the back of a frog tied to a silver plate by means of silk strings1 7,plate ,,iv4 fig4 #d47 and two metallic chains were suspended in such a manner1 that by pushing down the rod the extremity of the one chain could be made to touch the silver plate1 and the extremity of the other the tin armature3 when an arc was by these means formed1 contractions instantly took place4 ,the frog began to breathe with difficulty1 to be agitated with convulsive movements1 and to be seized with an universal tremor1 so that its last moment seemed to be approaching2 but on air being admitted into the receiver1 it recovered and appeared as lively and active as before4 ,on examining more closely the changes which had taken place in the animal while in this state1 which was certainly contrary to nature1 ,i found the muscles red with a superabundance of blood3 but when dissected in the usual manner1 they exhibited strong signs of animal electricity2 for1 on applying an arc to the nerves or muscles1 without any armature1 violent contractions were produced1 and continued for a long time1 provided care was taken that there should be no deficiency of animal moisture4 ,that such a quantity of electricity should be excited1 will not seem astonishing to those who have seen more violent electric commotions excited in the animal machine by the action of a needle4 ,this indeed has been placed beyond all doubt by an observation of ,gardini1 who says 8that having made some experiments with a large torpedo1 he remarked that stronger convulsions were produced when the animal was subjected to great pain by any means1 such as pricking it with a needle#i40 ,the phnomena exhibited by a vacuum or rarefied air1 were exhibited also by condensed air1 so that very powerful contractions were produced by one homogeneous arc4 ,for1 if the same apparatus described in ,plate ,,iv4 fig4 #d4 be adapted to a condensing machine1 a dead frog introduced into it will readily be contracted4 ,live frogs also1 after being kept for half an hour or a whole hour in air twice as dense as that of the atmosphere1 exhibited strong signs of electricity without any armature1 and merely by the application of a silver arc to the nerves and muscles4 ,,ix4 ,having made these experiments in vacuo and condensed air1 it was of some importance to try also what effect would be produced on animal electricity by the action of the ariform fluids4 ,the apparatus employed for this purpose was as follows3 ,i provided a glass vessel 7,plate ,,iv4 fig4 #c471 terminating at the upper extremity in a neck1 to which could be closely fitted1 when necessary1 a metallic cover1 having a perforation in the centre to receive a moveable rod1 which was connected with a transverse metal conductor supporting a frog prepared in the usual manner4 ,having filled the vessel with water1 or mercury1 which was still better1 ,i placed it on the shelf of a pneumatic tub1 and introduced into it1 according to ,priestley's method1 any particular gas4 ,some water or mercury was put into the dish to which it was afterwards removed2 and the metal cover1 having a frog suspended from it1 being then fitted to the neck of the vessel1 the frog by means of this apparatus could be immersed at pleasure in carbonic acid gas1 hydrogen1 or any other kind of gas2 so that the constancy of animal electricity might be tried in either4 ,it is evident that1 by letting down the spinal marrow of the frog1 and the end of the conductor to the surface of the water or mercury1 by means of the rod1 an arc will be formed1 and that muscular contractions must then be produced4 ,the same experiment may be performed by means of a bottle 7,plate ,,iv4 fig4 #f47 furnished with a cover like the former4 ,after being filled with water or mercury1 it is inverted on the shelf of the pneumatic tub1 and the gas is then introduced in the usual manner2 but care must be taken not to displace the whole of the water or mercury1 as a portion must be left to cover the bottom when the jar is turned up4 ,this experiment ,i tried only with oxygen gas1 reserving the other kinds of air till a more convenient opportunity4 ,x4 ,to give more weight to these experiments in vacuo1 ,i endeavoured to prevent all those errors which arose1 or might be suspected to arise1 from the introduction of air2 for ,i supposed that some opponent of the theory of animal electricity1 while endeavouring to find out objections against it1 since there was no foundation for asserting that the vacuum afforded any electricity to the animals1 might pretend that1 the plate of the pneumatic machine being metal1 according to custom1 some electricity from the atmosphere might be attracted by it1 and be thus conveyed even through a vacuum to the animals4 ,on this account it was necessary that a vacuum should be formed1 without placing the receiver on a metallic plate2 without the contact of any conducting bodies1 and in such a manner as to show that the electricity excited was that really existing in the animals4 ,i therefore employed a glass receiver 7,plate ,,iv4 fig4 #i47 cut into two parts above its middle1 between which was placed a horizontal partition1 in order that the upper part might be filled with oil1 or some non-conducting body4 ,the partition was perforated with a large aperture1 the superior edges of which projected a little upwards2 and the lower1 projecting downwards1 were furnished with small circular grooves1 so that the hole could be shut by a piece of bladder tied over it with thread4 ,a sharp-pointed rod was placed over the hole1 so that1 being let down by a non-conducting handle1 it could be made to pierce the bladder4 ,this1 however1 was to be done only when the lower part of the receiver was exhausted of air2 for the oil1 when the air is withdrawn1 speedily falls down3 by these means a vacuum is formed in the upper part1 and1 in consequence of the interposed stratum of the oil1 remains insulated1 as it can receive no electricity from the metallic plate of the machine1 nor from other conducting bodies4 ,but it will be in vain to attempt to form a vacuum in this manner1 unless the parts of the cut glass be so fitted as to prevent entirely the admission of external air4 ,a very simple and ingenious apparatus1 for the same purpose1 was invented by ,f4 ,borelli3 in order to stop the efflux of the oil at pleasure1 he adapted to the hole a glass cone1 by which means he was enabled to produce an insulated vacuum of greater or less capacity in the upper part of the receiver4 ,here then ,i had a vacuum every where surrounded with non-conducting bodies1 so that1 if animal electricity were excited in it1 there could be no reason for ascribing it to electricity borrowed from the atmosphere4 ,,xi4 ,i adapted to a glass rod1 in a longitudinal direction1 a metallic plate1 7,plate ,,iv4 fig4 #g47 which at the upper extremity was bent into a right angle1 and supported the spinal marrow of a frog1 so that it might be considered as a lengthened conductor of the nerves4 ,this plate was inserted into a glass receiver1 so as to move in it with ease2 and by means of a screw could be fixed at any altitude whatever4 ,an accurate representation of this apparatus1 with the glass rod annexed1 is seen in ,plate ,,iv4 fig4 #h4 ,iron hooks fixed to the feet of the suspended frog acted the part of a conductor to the muscles2 and the upper part of the receiver being exhausted of air1 as above described1 a stratum of oil was still left to separate the frog from the partition4 ,to guard against all danger from the action of any internal metallic body1 a strong magnet was applied to the iron conductor of the muscles1 which1 immediately obeying the power of attraction1 fell upon the conductor of the nerves2 and thus a circuit of animal electricity from the muscles to the nerves being speedily effected#aj1 contractions were immediately produced4 ,when ,i communicated this experiment to the ,institute1 ,i was extremely desirous that the apparatus ,i had here invented for the purposes of animal electricity might be of some advantage to the science of philosophy in general1 of which ,i was always fond1 and which formed the chief object of my study4 ,but it is necessary that ,i should mention to what ,i more particularly allude4 ,,xii4 ,such bodies as had hitherto been put into the air pump were gradually subjected to the action of a vacuum4 ,hence it appeared that the apparatus above described might be attended with a considerable degree of utility2 as in future1 any body whatever1 whether solid or fluid1 might be subjected to this action at once4 ,for1 the lower part of the receiver being deprived of its internal air1 if the bladder be burst by means of the glass rod1 the fluid will run down and occupy the space emptied of air1 leaving a vacuum in the upper part4 ,when the fluid has thus fallen to the lower part of the receiver1 solid bodies even1 if any were immersed in it while in the upper part of the receiver1 will also experience the action of the vacuum4 ,but liquid bodies are of such a nature1 that they have united with them certain ariform fluids1 which1 when the pressure of the air is removed1 readily expand4 ,a fluid1 therefore1 when it has fallen to the lower part of the receiver1 being agitated and thrown into a state of perturbation by the motion1 its most subtle principles will be extricated1 and fill the capacity of the bell4 ,the vacuum will then be disturbed by the evaporation1 which1 acting on the mercury in the barometer connected with the air pump1 will cause it to fall4 ,but every one acquainted with the principles of philosophy must know1 that the depression of the mercury in the barometer will be greater1 according as a greater quantity of ariform fluids has been disengaged in the receiver2 and if the degree of pressure in the barometer varies according to the variety of ariform principles1 it may be readily seen1 that this method may be employed to determine the quantity of them1 or their elasticity1 since they are cut off from all communication with the surrounding atmosphere1 though it still exercises its pressure upon them4 ,,xiii4 ,the vacuum here obtained in the upper part of the bell1 seems to be far superior to that produced in the lower part1 according to the usual method4 ,for it has long been a complaint among philosophers1 that by working the air pump the air is only rarefied1 till it no longer possesses elasticity capable of raising the valve1 so that it is impossible to produce a complete vacuum by this method4 ,if we can credit the followers of ,euler1 that subtle fluid1 which they call ether1 and which permeates every thing1 still remains2 for1 adopting the opinion of the antient ,peripatetics1 they consider a vacuum as beneath the dignity of nature4 ,but1 setting aside this question1 ,i shall only observe1 that if a vacuum be formed in the upper part of the receiver1 by the method above described1 it does not appear that it can be disturbed by any thing from without1 and the gravity of the falling fluid will not suffer itself to be overcome by the subtle ether1 if any really exists4 ,should it be apprehended that the air contained in the oil may be disengaged1 and disturb the vacuum1 you may substitute in its stead mercury or water1 which can be deprived of air either by boiling or by long exposure to the action of a vacuum4 ,but before any thing certain on this subject can be said1 new and repeated experiments will be necessary4 ,as every objection that could be made in regard to a vacuum seems now to be obviated1 since a space perfectly free from common air can be produced1 and cut off from all communication with the atmosphere1 or with conducting bodies1 ,i shall return to animal electricity1 from which ,i was led by a desire of contributing towards the improvement of natural philosophy in general4 ,,xiv4 ,those who attempt to determine the velocity of the nervous fluid in a given time1 undertake a matter of great difficulty1 respecting which nothing certain can be known4 ,haller rejected the suppositions of those who1 comparing the tenuity of the nervous tubes of the heart with the large branch of the aorta1 were of opinion1 that the velocity of the nervous fluid must be two thousand eight hundred and eighty times greater than that of the blood4 ,this celebrated physician1 distrusting hypothesis1 had recourse to experiment1 and found that the velocity of the nervous fluid would be no less than nine thousand feet in the first minute4 ,but in this determination of the velocity of the nervous fluid there seems to be some difficulty1 which perhaps ought to be ascribed rather to the period when that celebrated man lived1 than to his want of sagacity or accuracy4 ,had ,haller possessed the means of conveying the nervous fluid with his own hands to different parts at pleasure1 he would no doubt have given us some more certain ideas respecting its rapid motion4 ,i resolved1 therefore1 not to neglect those advantages with which the modern philosophy has been enriched1 and to employ very long metallic arcs1 by which ,i could direct the animal electricity as ,i pleased4 ,a staircase which reached from the top to the bottom of the house1 with many windings1 presented me with an iron plate1 exceedingly convenient for the transmission of animal electricity4 ,a metal wire1 brought down from the top of the staircase1 was connected with the iron plate1 and by these means ,i obtained an arc1 the length of which was above one hundred and fifty feet4 ,when this arrangement was made1 the two extremities of this very long arc were applied to the armed nerves and muscles of a frog2 and the animal electricity being thus excited1 instantly proceeded with so much velocity from the one extremity of the arc to the other1 that no difference could be perceived between the time when the frog touched the arc1 and that when it began to be agitated4 ,but to show that this result was not owing entirely to the metallic conductor1 ,i employed long ropes dipped in salt water1 and always with the same effect4 ,this circumstance seems to prove1 in a striking manner1 a great similarity between the nervous fluid and common electricity1 and to overturn the opinion of ,haller1 who1 according to his calculations1 makes the nervous fluid require a second for passing over the space of #aej feet4 ,,xv4 ,according to ,beccaria1 a celebrated observer of the propagation of the electric fluid1 there are two ways of its being transmitted2 one when it flows through conducting bodies only1 and the other when1 being collected in non-conducting bodies1 it proceeds from the coating electric by excess to that which is in the contrary state4 ,in the one case1 ,beccaria establishes a certain time for its passage2 in the other he allows none4 ,this celebrated man observed1 that the electric matter was conveyed from the conductor of a machine1 along a metallic wire #ejj feet in length1 in the course of a second2 in its passage along a hempen rope of the same length1 it employed seven seconds2 but when the rope was moistened with water1 it required only two or nearly three vibrations of a pendulum4 ,when he discharged a ,leyden flask by the longest conductor1 he was never able to observe the least interval of time4 ,the same thing was remarked by ,jallabert1 ,sigaud de la ,fond1 and other philosophers1 who performed their experiments1 not in an apartment but in the open air2 and conveyed the electric fluid in this manner for a considerable distance along the banks of large rivers4 ,monnier extended two iron wires#aa in an open field1 parallel to each other1 for the distance of #eajg feet2 and a man placed between them held in his hands the extremity of the conductors1 keeping them at a little distance from his body4 8,but the man1 who was in the middle of the arc10 says the author1 8while he saw the spark issue from the jar1 received the shock3 he could have distinguished the smallest interval of time between the explosion and the shock2 and if it had amounted to the fourth part of a second1 it could have easily been remarked40 ,,xvi4 ,while reflecting on these facts1 ,i formed a conjecture from the great celerity with which animal electricity is conveyed1 respecting the manner in which it is evolved4 ,if the animal electricity were conveyed from a muscle to a nerve1 or vice versa1 in the same manner as the common electric fluid is conveyed from the machine by the chain1 it would have been observed to employ some time1 however small1 in its passage4 ,as ,i at first ascribed this to the shortness of the conductor ,i had used1 ,i extended it to more than #bej ,parisian feet1 and applied the nerves and muscles of a frog to this new conductor in the manner above described1 without observing the least obstacle to the passage of the electric fluid4 ,as this arc formed a half of that employed by ,beccaria1 the space of half a second would have been required1 if we consider in this passage only one kind of electricity4 ,but the half second required according to the observations of ,beccaria was not observed3 it therefore appears1 that this propagation of animal electricity ought not to be referred to the first-mentioned case1 but to that where equilibrium is restored between the negative and positive state4 ,,xvii4 ,this rapid conveyance of animal electricity1 however1 is entirely stopped1 if the metallic arc be intercepted1 not only by non-conducting but by certain conducting bodies4 ,here then we have again occasion for the action of two contrary kinds of electricity4 ,for the electric matter1 whether positive or negative1 when conveyed from the machine to the chain1 pervades all bodies in the same manner1 provided they be conductors4 ,thus the metallic conductor of the machine1 the insulated person1 and all other bodies that may be connected with it1 become electric in the same manner4 ,but the same electric matter collected in non-conducting bodies requires1 before it can be discharged1 certain conditions in the conducting bodies by which it is discharged4 ,when the metallic arc is interrupted by a little water1 the ,leyden flask1 if it contain a moderate quantity of electricity1 cannot be discharged2 for the two contrary kinds of electricity to be discharged require that every part of the arc should be equally endowed with the property necessary for conducting the electric fluid4 ,but in the case of only one kind of electricity1 it would pass with great readiness either through water or metal4 ,let us now apply these phnomena of general electricity to the theory of animal electricity4 ,in the experiment mentioned in the sixth section1 if only one kind of electricity proceeded from the nerves or the muscles1 it would be immediately conveyed from the nerve to the metal1 then to the vacuum back to the metal1 and thence to the muscle1 as being the place from which it issued4 ,besides1 the electricity propagated in this manner would have produced contractions1 which however were not observed4 ,the progress of the animal electricity1 therefore1 experienced considerable obstacles1 not only from non-conducting but also from conducting bodies2 which affords a strong proof that electricity exists and is collected in the muscular fibre1 in the same manner as in non-conducting bodies4 ,but the remarkable quickness of the progress of animal electricity leads me to the ,leyden flask2 and therefore ,i shall here say a few words respecting the analogy between the phnomena it exhibits1 and those of animal electricity2 and give an account of the reasons which first induced me to enter on this comparison4 ,,xviii4 ,when public meetings were held at the house of ,galvani1 for the purpose of discussing the theory of animal electricity1 great doubts were entertained respecting two contrary kinds of electricity acting in animals4 ,the reasoning on this subject1 which displays acuteness and ingenuity1 was as follows3 ,if two kinds of electricity1 one positive and the other negative1 prevailed in the nerves and muscles of animals1 on applying the muscles of one frog to the armed nerve of another1 we should observe contractions2 which however is not found to be the case4 ,the proposed doubt1 however1 gave me considerable uneasiness1 as the dispute on that subject seemed to lay a foundation for many objections against the theory of animal electricity4 ,but the novelty of this event will excite no astonishment in those who consider the subject with attention3 nay1 it would rather seem astonishing if the matter were otherwise4 ,the phnomena in the above experiment are perfectly agreeable to the laws of general electricity1 and to the theory of the new animal ,leyden flask4 ,for1 if we suppose the muscles of the frog furnished with nerves to represent so many ,leyden flasks1 no contractions ought to be expected from them1 in circumstances under which ,leyden flasks themselves would produce no explosion4 ,this we always observe in two electric jars1 neither of which is discharged when the arc is established between the exterior coating of the one and the interior coating of the other4 ,if the muscles1 therefore1 in the above experiment1 represent ,leyden flasks1 in cases in which no explosion could take place in the latter no contractions can be observed in the former4 ,,xix4 ,for the sake of illustrating the proposed analogy1 it will be proper that ,i should here explain the conditions under which contractions are produced by the application of two frogs to each other1 and compare them with the phnomena of the ,leyden flasks4 ,i shall therefore show1 in a few words1 the different methods in which several frogs are made to contract at the same time1 and in which ,leyden jars are discharged4 ,place on a glass plate two frogs1 one of which has its spinal marrow armed1 and let a communication be established between its muscles and the spinal marrow of another frog1 by means of a small metallic chain4 ,if the arc be formed from the armed spinal marrow of the one frog to the muscles of the other1 contractions will be produced in both4 ,let us now apply to ,leyden flasks the arrangement followed with the frogs4 ,if two electric ,leyden jars stand on a glass plate1 when an arc is applied1 some electricity will be elicited2 but an absolute explosion will never be produced4 ,if one extremity of a metallic wire1 however1 be brought in contact with the inside of one of the ,leyden jars1 and the other with the exterior coating of the other1 on applying an arc to the other two coatings1 which have no communication with the metallic wire that has been added1 an explosion will take place1 and both the jars will be discharged4 ,but the above contractions may be produced in a manner still simpler4 ,if the spinal marrow of one frog be united to the muscles of another1 as soon as an arc is formed from the spinal marrow of the armed frog to the remote muscles of the other1 strong contractions will be produced in both4 ,the analogy between animal and artificial electricity1 which is the object of our research1 will always be apparent in this experiment4 ,two charged ,leyden flasks1 suspended in such a manner from the conductor of the machine that the exterior coating of the one is connected with the interior coating of the other1 form a very happy representation of the frogs2 for1 the same arc being applied1 and in the same manner1 both to the frogs and the ,leyden flasks1 when an explosion is produced by the latter contractions will take place in the former4 ,,xx4 ,hitherto the contractions have been produced by establishing the arc from the nerve of one frog to the muscles of another3 but contractions will take place in both1 if the arc be conveyed from the armed spinal marrow of the one to the armed spinal marrow of the other1 provided care be taken that corresponding muscles communicate alternately with the conducting body4 ,but it is much more difficult to reconcile this phnomenon than the former to the general laws of electricity4 ,this difficulty1 however1 may be obviated1 if we suppose that the one frog1 in consequence of its natural moisture1 forms an arc to the other4 ,this indeed was first confirmed by the experiments of ,galvani2 for1 having divided a frog lengthwise1 both parts were connected merely by their moisture#ab4 ,yet1 when the arc touched one of the separated parts1 the other was immediately contracted4 ,as this explanation is so obvious1 nothing further needs be said on the subject4 ,but ,i was unwilling to leave in a state of uncertainty the analogy between the phnomena of animal electricity and those of the ,leyden flask1 the wonderful agreement of which had so much excited my astonishment3 and indeed ,i had no cause to repent of my perseverance2 for1 though it did not enable me to attain to what ,i proposed1 it conducted me to some general phnomena of electricity1 which no one perhaps had before made an object of research4 ,i discovered that one ,leyden flask may be applied as an arc to another4 ,i provided two insulated ,leyden jars of the same capacity1 one of them charged and the other uncharged1 and established a communication between the exterior coating of both1 by means of a conducting body2 and having then formed an arc from the interior coating of the one to that of the other1 there was an immediate transmission of the electricity with an explosion2 and at the same time the flask which at first was uncharged became charged4 ,if ,i formed an arc with my arms and hands1 ,i experienced a considerable shock during the passage of the electric fluid4 ,when ,i observed this effect1 ,i conceived it was not contrary to the principles of philosophy to suppose that the one frog1 in respect to the other1 represented a ,leyden flask1 and at the same time acted the part of an arc4 ,,xxi4 ,some1 perhaps1 will object to this analogy1 that in the above experiments the flask destitute of electricity forms the arc2 while1 on the contrary1 both flasks ought to be charged to represent properly the muscles and nerves of frogs1 which both possess electricity4 ,but the very same phnomenon is observed in two charged flasks1 provided one of them is charged with more electricity than the other4 ,hence1 in support of our analogy1 we need only assume1 that the quantity of electricity in the one frog is a little different from that of the other2 a supposition which1 in forming an hypothesis1 the severest philosopher may allow4 ,i shall say nothing of the great variety and connection of the elements of which animal bodies are composed1 and which on this account require a difference in the quantity of the animal electricity4 ,it appears by some late experiments of ,valli#ac1 that animal electricity is discharged in the same manner as that which is collected in non-conducting bodies4 ,it is likewise proved1 that the same arc and the same armatures1 according to the various consensus and connection of the nerves1 and according to the different positions in which they are applied1 elicit a larger or smaller quantity of electricity1 and sometimes none at all4 ,those indeed who consider these observations will hardly think it possible1 when animal ,leyden flasks consist of so many different parts1 that there should not be some difference in the electricity collected4 ,but there is no need of employing conjecture in regard to a point1 which is confirmed not only in regard to animals1 but in all conducting bodies1 by the ingenious observations of ,coulomb#ad2 for it is fully established that the electric matter is communicated and accumulated different ways on the surface of conducting bodies4 ,but if this phnomenon takes place in conducting bodies the parts of which are homogeneous1 there is no reason to deny that it may appear in animals in which provident nature has so intermixed conducting with non-conducting parts1 in order that the action of animal electricity might not be short and transient1 but constant and durable4 ,,xxii4 ,but if the diversity in the structure of animal bodies require that the force and power of the animal electricity1 collected in the corresponding muscles1 should be different1 a singular agreement will appear between the phnomena of the ,leyden flask and those of animal electricity4 ,if an insulated person touch two flasks containing equal quantities of electricity1 however great1 he will experience no shock2 but if one of the flasks contain a greater charge than the other1 he will receive a shock according to the ratio of the difference of the electricity of the flasks4 ,though the frogs therefore represent two ,leyden flasks1 one of them may act the part of an arc1 and produce an equilibrium1 provided it be allowed that there is a difference between the quantities of the electricities collected4 ,i have here endeavoured to establish the proposed analogy1 not because ,i suppose the muscles to be so many ,leyden flasks1 such as they are exhibited to us by the ingenuity of philosophers1 but in order to show that many phnomena are common to both2 nor have ,i applied animal electricity to explain all the phnomena of muscular motion1 with a view of obtaining applause from those who are zealous advocates for this theory4 ,i must also observe1 that if in the prosecution of this object ,i have met with any anomalies1 ,i do not on that account despise the agreement of the laws of philosophy which have been established by so much labour4 ,several of the phnomena observed by ,galvani and others have served me as a foundation for the proposed analogy1 and induced me to extend1 if possible1 its boundaries4 ,but going back to the origin of animal electricity1 since it belongs to the subject1 ,i shall here take a general view of the whole1 and express the substance of it in a few corollaries4 ,,xxiii4 ,the corollaries ,i propose will follow the order of time in which they arose1 and therefore will express the gradual improvement of animal electricity4 #a4 ,animal electricity passes freely through bodies which possess nearly the same degree of conducting power1 but it does not pass through non-conducting bodies4 #b4 ,it is affected by the obstacles which occur1 not only in non-conducting but in conducting bodies1 as well as by their varieties2 and if these obstacles be numerous1 its passage is stopped3 but if it be possible to overcome them1 the impediment causes it to make a more powerful effort to attain to a state of equilibrium4 ,hence1 unlike armatures and arcs are of great effect in exciting a moderate degree of electricity1 when the same electricity resists the power of a homogeneous metal4 #c4 ,animal electricity obeys the law of equilibrium2 for1 when the muscles have been brought to a state of equilibrium with the corresponding nerves1 no contractions are produced by the application of an arc2 but if that which produces the equilibrium be removed1 the contractions immediately take place4 #d4 ,poisons1 mephitic air1 ariform fluids1 and condensed air1 do not prevent animal electricity from being excited4 #e4 ,the influence of a vacuum on animal electricity is various4 ,in dead animals1 if kept a long time in vacuo1 the animal electricity is weakened3 in living animals it is considerably increased4 #f4 ,though a vacuum does not prevent the electricity from being excited1 it will not serve as a conductor of it when it has been excited3 if an arc from the nerves to the muscles be intercepted by the smallest vacuum1 no contractions take place4 #g4 ,as metallic armatures are of great effect in attracting and collecting artificial electricity1 the case is the same with animal electricity2 but care must be taken not to ascribe to them that electricity which the muscles naturally possess4 #h4 ,though unlike armatures have a great effect in calling forth animal electricity1 we have reason to conclude from several experiments1 that they do not contain two kinds of electricity capable of producing muscular motion4 #i4 ,as natural electricity issues with great force from sharp-pointed bodies1 and proceeds to them more readily than to others1 the case is the same in regard to animal electricity1 as it issues more readily from the pointed parts of the metallic arming applied to the nerves and muscles4 #aj4 ,the nervo-electric fluid is propagated with that rapidity which is required in restoring to an equilibrium two opposite kinds of electricity4 #aa4 ,the same conditions which cause two flasks to be discharged when an arc is established from the exterior coating of the one to the interior coating of the other1 excite contractions in two frogs1 when an arc is formed from the nerve of one to the muscles of the other4 #ab4 ,the arc applied as above mentioned to the interior coating of two phials1 and to the nerves of two frogs1 seems to give more force to the proposed analogy2 for the electric explosions have a great similarity to the muscular motions excited in the frogs4 ,i might have enlarged the number of these corollaries1 had not the well-known fate of various opinions1 now consigned to oblivion1 rendered me more timid in hazarding conjectures4 ,i1 however1 did not allow myself to think that ,i ought so far to give way to my timidity as to check the spirit of inquiry1 or to abandon the hope of one day attaining to the truth4 ,but it would be unreasonable to expect in animal electricity1 which is yet in its infancy1 that precision and those satisfactory results which can be the work only of time1 and of the continued labour of philosophers4 #g ,as this term is improperly used by philosophers1 ,i must here observe1 that ,i shall in future understand by it air highly rarefied by the usual means4 #h ,in the description of a new air-pump of his invention1 where he shows that electricity cannot pass through a vacuum1 he adds3 8,there can be little doubt1 from the above experiment1 of the non-conducting power of a perfect vacuum2 and this fact is still more strongly confirmed by the phnomena1 which appear upon the admission of a very minute particle of air into the inside of the gauge4 ,in this case1 the whole becomes immediately luminous upon the slightest application of electricity2 and a charge takes place1 which continues to grow more and more powerful1 in proportion as fresh air is admitted1 till the density of the conducting medium arrives at its maximum4 ,an ,essay on ,electricity1 explaining the ,theory and ,practice of that useful ,science4 ,third edit4 ,london1 #aghg4 #i ,josephi ,gardini de ,electrici ,ignis ,natura ,dissertatio1 ,regi ,scientiarum ,academi ,mantuan exhibita1 ,mantu #agib1 p4 #ajj4 #aj ,this may be accomplished in a much more simple manner1 without the aid of a magnet1 by connecting a wire with the lower part of the nerves1 and applying the wire to the muscles by turning the rod round4 #aa ,prcis historique et exprimental des ,phnomnes lectriques1 par ,m4 ,sigaud de la ,fond1 ,paris #agha1 sect4 i4 art4 #d4 #ab ,aloysii ,galvani de ,viribus ,electricitatis in ,motu musculari ,commentarius1 ,mutin iterum editus1 p4 #bi4 #ac ,m4 ,valli ,cinquime et ,huitime ,lettre sur l',electricit ,animale1 dans ,observations sur la ,physique1 par ,m4 l',abb ,rozier1 tom4 xlii4 ,paris1 #agib4 #ad ,recherches sur la ,distribution de ,fluide ,electrique entre plusieurs ,corps ,conducteurs1 et la ,dtermination de la ,densit ,electrique dans les diffrens ,parties de la ,surface de ces ,corps4 ,mem4 de l',acad4 ,royale des ,sciences1 ,an4 #aghh4 ,,conclusion4 ,i publish my experiments respecting muscular contractions produced by one metal with the greater confidence1 as they were repeated different ways by the celebrated ,humboldt1 who has adopted my opinion4 ,in his work on ,galvanism1 under the head which he entitles 8,answer to the ,objections made by ,volta to the ,experiments of ,aldini10 he says1 8,j4 ,aldini of ,bologna invented a very ingenious apparatus1 by means of which he was enabled to refute the supposition of ,professor ,volta4 ,for this purpose he had recourse to mercury3 every thing relating to his experiments is very well represented in the plate which accompanies his memoir4 ,volta1 in reply to these experiments1 observes1 that they can impose only on those who have not thoroughly examined them4 ,he denies the facts related by ,aldini1 and persists in his opinion that the phnomena of ,galvanism may all be referred to the laws of heterogeneity4 ,in regard to the experiments made with mercury1 he says that there is a great difference between the surface of this metal and the interior of its mass2 because the surface becomes oxidated by the contact of the atmospheric air2 that consequently1 in the experiment of ,aldini1 the conducting arc is not really but apparently homogeneous1 the organs being immersed to different depths in the metal3 besides1 that the mercury in these experiments produces a shock2 and that1 as this shock is not the same at both extremities of the arc1 the result is an unequal development of electricity4 ,volta1 therefore1 opposes to the phnomena described by ,aldini nothing but hypothesis4 ,we might reply in the same manner2 but as it is much better in philosophical disputes to have recourse to experiments1 ,i undertook some researches for the purpose of removing all doubt in regard to this subject4 8,i purified mercury by all the known means employed for that purpose4 ,i strained it several times through a piece of chamois leather2 ,i washed it with water and soap1 with vinegar and with alcohol4 ,it appeared to me that it contained neither lead nor tin2 and that it was free from oily particles and dust3 it was perfectly fluid1 and divided itself into small1 very round globules1 which did not adhere to each other1 and which left behind them no traces4 ,its surface was as brilliant as that of glass1 without any pellicle or spot2 and a small quantity of it being stirred in a mortar with water1 did not communicate to it any sensible colour4 ,it dissolved in nitric acid without sensible effervescence1 and without giving any precipitate4 ,a large quantity of mercury thus purified was poured into three porcelain vessels2 and as ,i was aware that1 if ,i performed several experiments with the same quantity of mercury1 it might be objected1 that the metal had contracted some impurity by the mere contact of the animal substances1 ,i made only one experiment with the mercury in each of the vessels4 8,i prepared several legs of frogs in such a manner that a portion of the crural nerve and a part of the muscle of the same length were left dependent4 ,i placed a glass tube in a horizontal direction above a vessel containing mercury2 made fast to it two silk threads1 and suspended from it the thigh of the leg in such a manner that the nerve and muscle could be made to descend at pleasure4 ,i brought the leg of the frog within two lines of the vessel1 and then lengthened the thread till the nerve touched the surface of the metal4 ,no contractions took place2 but as soon as the nerve also was brought into contact with the metal1 by lengthening the silk thread1 the whole limb experienced a convulsive shock4 ,i repeated this experiment with the same precaution1 employing the two other vessels1 and the same results were obtained4 8,the muscle and nerve touched the mercury only at the surface2 they were in no manner immersed in the metal2 and care had been taken to lower them so gently1 that it was impossible to suspect there could be any impulse1 as in the experiment where ,aldini had caused the mercury to flow down by employing a vessel shaped somewhat like a syphon40 ,,appendix4 ,no4 ,i4 ,an ,account of the ,experiments performed by ,j4 ,aldini on the ,body of a ,malefactor executed at ,newgate ,jan4 #agth #ahjc4 ,,introduction4 ,the unenlightened part of mankind are apt to entertain a prejudice against those1 however laudable their motives1 who attempt to perform experiments on dead subjects2 and the vulgar in general even attach a sort of odium to the common practice of anatomical dissection4 ,it is1 however1 an incontrovertible fact1 that such researches in modern times have proved a source of the most valuable information1 in regard to points highly interesting to the knowledge of the human frame1 and have contributed in an eminent degree to the improvement of physiology and anatomy4 ,enlightened legislators have been sensible of this truth2 and therefore it has been wisely ordained by the ,british laws1 which are founded on the basis of humanity and public benefit1 that the bodies of those who during life violated one of the most sacred rights of mankind1 should after execution be devoted to a purpose which might make some atonement for their crime1 by rendering their remains beneficial to that society which they offended4 ,in consequence of this regulation1 ,i lately had an opportunity of performing some new experiments1 the principal object of which was to ascertain what opinion ought to be formed of ,galvanism as a mean of excitement in cases of asphyxia and suspended animation4 ,the power which exists in the muscular fibre of animal bodies some time after all other signs of vitality have disappeared1 had before been examined according to the illustrious ,haller's doctrine of irritability2 but it appeared to me that muscular action might be excited in a much more efficacious manner by the power of the ,galvanic apparatus4 ,in performing these experiments1 ,i had another object in view4 ,being favoured with the assistance and support of gentlemen eminently well skilled in the art of dissection1 ,i proposed1 when the body should be opened1 to perform some new experiments which ,i never before attempted1 and to confirm others which ,i had made above a year ago on the bodies of two robbers decapitated at ,bologna4 ,to enlarge on the utility of such researches1 or to point out the advantages which may result from them1 is not my object at present4 ,i shall here only observe1 that as the bodies of valuable members of society are often found under similar circumstances1 and with the same symptoms as those observed on executed criminals2 by subjecting the latter to proper experiments1 some speedier and more efficacious means than any hitherto known1 of giving relief in such cases1 may1 perhaps1 be discovered4 ,in a commercial and maritime country like ,britain1 where so many persons1 in consequence of their occupations at sea1 on canals1 rivers1 and in mines1 are exposed to drowning1 suffocation1 and other accidents1 this object is of the utmost importance in a public view1 and is entitled to every encouragement4 ,forster1 on whose body these experiments were performed1 was twenty-six years of age1 seemed to have been of a strong1 vigorous constitution1 and was executed at ,newgate on the #agth of ,january #ahjc4 ,the body was exposed for a whole hour in a temperature two degrees below the freezing point of ,fahrenheit's thermometer2 at the end of which long interval it was conveyed to a house not far distant1 and1 in pursuance of the sentence1 was delivered to the ,college of ,surgeons4 ,mr4 ,keate1 master of that respectable society1 having been so kind as to place it under my direction1 ,i readily embraced that opportunity of subjecting it to the ,galvanic stimulus1 which had never before been tried on persons put to death in a similar manner3 and the result of my experiments ,i now take the liberty of submitting to the public4 ,before ,i conclude this short introduction1 ,i consider it as my duty to acknowledge my obligations to ,mr4 ,,carpue1 lecturer on anatomy1 and ,mr4 ,,hutchins1 a medical pupil1 for the assistance they afforded me in the dissection4 ,i was also much indebted to ,mr4 ,,cuthbertson1 an eminent mathematical instrument maker1 who directed and arranged the ,galvanic apparatus4 ,encouraged by the aid of these gentlemen1 and the polite attention of ,mr4 ,,keate1 ,i attempted a series of experiments1 of which the following is a brief account4 ,,experiment ,i4 ,one arc being applied to the mouth1 and another to the ear1 wetted with a solution of muriate of soda 7common salt71 ,galvanism was communicated by means of three troughs combined together1 each of which contained forty plates of zinc1 and as many of copper4 ,on the first application of the arcs the jaw began to quiver1 the adjoining muscles were horribly contorted1 and the left eye actually opened4 ,,experiment ,,ii4 ,on applying the arc to both ears1 a motion of the head was manifested1 and a convulsive action of all the muscles of the face3 the lips and eyelids were also evidently affected2 but the action seemed much increased by making one extremity of the arc to communicate with the nostrils1 the other continuing in one ear4 ,,experiment ,,iii4 ,the conductors being applied to the ear1 and to the rectum1 excited in the muscles contractions much stronger than in the preceding experiments4 ,the action even of those muscles furthest distant from the points of contact with the arc was so much increased as almost to give an appearance of re-animation4 ,,experiment ,,iv4 ,in this state1 wishing to try the power of ordinary stimulants1 ,i applied volatile alkali to the nostrils and to the mouth1 but without the least sensible action3 on applying ,galvanism great action was constantly produced4 ,i then administered the ,galvanic stimulus and volatile alkali together2 the convulsions appeared to be much increased by this combination1 and extended from the muscles of the head1 face1 and neck1 as far as the deltoid4 ,the effect in this case surpassed our most sanguine expectations1 and vitality might1 perhaps1 have been restored1 if many circumstances had not rendered it impossible4 ,,experiment ,v4 ,i next extended the arc from one ear to the biceps flexor cubiti1 the fibres of which had been laid bare by dissection4 ,this produced violent convulsions in all the muscles of the arm1 and especially in the biceps and the coraco brachialis even without the intervention of salt water4 ,,experiment ,,vi4 ,an incision having been made in the wrist1 among the small filaments of the nerves and cellular membrane1 on bringing the arc into contact with this part1 a very strong action of the muscles of the fore-arm and hand was immediately perceived4 ,in this1 as in the last experiment1 the animal moisture was sufficient to conduct the ,galvanic stimulus without the intervention of salt water4 ,,experiment ,,vii4 ,the short muscles of the thumb were dissected1 and submitted to the action of the ,galvanic apparatus1 which induced a forcible effort to clench the hand4 ,,experiment ,,viii4 ,the effects of ,galvanism in this experiment were compared with those of other stimulants4 ,for this purpose1 the point of the scalpel was applied to the fibres1 and even introduced into the substance of the biceps flexor cubiti without producing the slightest motion4 ,the same result was obtained from the use of caustic volatile alkali and concentrated sulphuric acid4 ,the latter even corroded the muscle1 without bringing it into action4 ,,experiment ,,ix4 ,having opened the thorax and the pericardium1 exposing the heart in situ1 ,i endeavoured to excite action in the ventricles1 but without success4 ,the arc was first applied upon the surface1 then in the substance of the fibres1 to the carne column1 to the septum ventriculorum1 and lastly1 in the course of the nerves by the coronary arteries1 even with salt water interposed1 but without the slightest visible action being induced4 ,,experiment ,x4 ,in this experiment the arc was conveyed to the right auricle1 and produced a considerable contraction1 without the intervention of salt water1 but especially in that part called the appendix auricularis3 in the left auricle scarcely any action was exhibited4 ,,experiment ,,xi4 ,conductors being applied from the spinal marrow to the fibres of the biceps flexor cubiti1 the gluteus maximus1 and the gastrocnemius1 separately1 no considerable action in the muscles of the arm and leg was produced4 ,,experiment ,,xii4 ,the sciatic nerve being exposed between the great trochanter of the femur and the tuberosity of the ischium1 and the arc being established from the spinal marrow to the nerve divested of its theca1 we observed1 to our astonishment1 that no contraction whatever ensued in the muscles1 although salt water was used at both extremities of the arc4 ,but the conductor being made to communicate with the fibres of the muscles and the cellular membrane1 as strong an action as before was manifested4 ,,experiment ,,xiii4 ,by making the arc to communicate with the sciatic nerve and the gastrocnemius muscle1 a very feeble action was produced in the latter4 ,,experiment ,,xiv4 ,conductors being applied from the sciatic to the peronal nerve1 scarcely any motion was excited in the muscles4 ,,experiment ,,xv4 ,the sciatic nerve being divided about the middle of the thigh1 on applying the conductors from the biceps flexor cruris to the gastrocnemius1 there ensued a powerful contraction of both4 ,i must here observe that the muscles continued excitable for seven hours and a half after the execution4 ,the troughs were frequently renewed1 yet towards the close they were very much exhausted4 ,no doubt1 with a stronger apparatus we might have observed muscular action much longer2 for1 after the experiments had been continued for three or four hours1 the power of a single trough was not sufficient to excite the action of the muscles3 the assistance of a more powerful apparatus was required4 ,this shows that such a long series of experiments could not have been performed by the simple application of metallic coatings4 ,i am of opinion that1 in general1 these coatings1 invented in the first instance by ,galvani1 are passive4 ,they serve merely to conduct the fluid pre-existent in the animal system2 whereas1 with the ,galvanic batteries of ,volta1 the muscles are excited to action by the influence of the apparatus itself4 99 99 99 99 99 ,from the above experiments there is reason to conclude3 ,i4 ,that ,galvanism exerts a considerable power over the nervous and muscular systems1 and operates universally on the whole of the animal conomy4 ,,ii4 ,that the power of ,galvanism1 as a stimulant1 is stronger than any mechanical action whatever4 ,,iii4 ,that the effects of ,galvanism on the human frame differ from those produced by electricity communicated with common electrical machines4 ,,iv4 ,that ,galvanism1 whether administered by means of troughs1 or piles1 differs in its effects from those produced by the simple metallic coatings employed by ,galvani4 ,v4 ,that when the surfaces of the nerves and muscles are armed with metallic coatings1 the influence of the ,galvanic batteries is conveyed to a greater number of points1 and acts with considerably more force in producing contractions of the muscular fibre4 ,,vi4 ,that the action of ,galvanism on the heart is different from that on other muscles4 ,for1 when the heart is no longer susceptible of ,galvanic influence1 the other muscles remain still excitable for a certain time4 ,it is also remarkable that the action produced by ,galvanism on the auricles is different from that produced on the ventricles of the heart1 as is demonstrated in ,experiment the tenth4 ,,vii4 ,that ,galvanism affords very powerful means of resuscitation in cases of suspended animation under common circumstances4 ,the remedies already adopted in asphyxia1 drowning1 c4 when combined with the influence of ,galvanism1 will produce much greater effect than either of them separately4 99 99 99 99 99 ,to conclude this subject1 it may be acceptable to the reader to have a short but accurate account of the appearances exhibited on the dissection of the body1 which was performed with the greatest care and precision by ,mr4 ,carpue4 8,the blood in the head was not extravasated1 but several vessels were prodigiously swelled1 and the lungs entirely deprived of air2 there was a great inflammation in the intestines1 and the bladder was fully distended with urine4 ,in general1 upon viewing the body1 it appeared that death had been immediately produced by a real suffocation40 ,it may be observed1 if credit can be given to some loose reports1 which hitherto it has not been in our power to substantiate1 that after this man had been for some time suspended1 means were employed with a view to put an end to his sufferings4 ,from the preceding narrative it will be easily perceived1 that our object in applying the treatment here described was not to produce re-animation1 but merely to obtain a practical knowledge how far ,galvanism might be employed as an auxiliary to other means in attempts to revive persons under similar circumstances4 ,in cases when suspended animation has been produced by natural causes1 it is found that the pulsations of the heart and arteries become totally imperceptible2 therefore1 when it is to be restored1 it is necessary to re-establish the circulation throughout the whole system4 ,but this cannot be done without re-establishing also the muscular powers which have been suspended1 and to these the application of ,galvanism gives new energy4 ,i am far from wishing to raise any objections against the administration of the other remedies which are already known1 and which have long been used4 ,i would only recommend ,galvanism as the most powerful mean hitherto discovered of assisting and increasing the efficacy of every other stimulant4 ,volatile alkali1 as already observed1 produced no effect whatever on the body when applied alone2 but1 being used conjointly with ,galvanism1 the power of the latter over the nervous and muscular system was greatly increased3 nay1 it is possible that volatile alkali1 owing to its active powers alone1 might convey the ,galvanic fluid to the brain with greater facility1 by which means its action would become much more powerful in cases of suspended animation4 ,the well known method of injecting atmospheric air ought not to be neglected2 but here1 likewise1 in order that the lungs may be prepared for its reception1 it would be proper previously to use ,galvanism1 to excite the muscular action1 and to assist the whole animal system to resume its vital functions4 ,under this view1 the experiments of which ,i have just given an account1 may be of great public utility4 ,it is with heartfelt gratitude that ,i recall to mind the politeness and lively interest shown by the members of the ,college of ,surgeons in the prosecution of these experiments4 ,mr4 ,keate1 the master1 in particular proposed to make comparative experiments on animals1 in order to give support to the deductions resulting from those on the human body4 ,mr4 ,blicke observed that on similar occasions it would be proper to immerse the body in a warm salt bath1 in order to ascertain how far it might promote the action of ,galvanism on the whole surface of the body4 ,dr4 ,pearson recommended oxygen gas to be substituted instead of the atmospheric air blown into the lungs4 ,it gives me great pleasure to have an opportunity of communicating these observations to the public1 in justice to the eminent characters who suggested them1 and as an inducement to physiologists not to overlook the minutest circumstance which may tend to improve experiments that promise so greatly to relieve the sufferings of mankind4 ,no4 ,,ii4 ,report presented to the ,class of the ,exact ,sciences of the ,academy of ,turin1 #aeth ,august #ahjb1 in regard to the ,galvanic ,experiments made by ,c4 ,,vassali-,,eandi1 ,,giulio1 and ,,rossi1 on the #ajth and #adth of the same ,month1 on the ,bodies of three ,men a short ,time after their ,decapitation4 ,by ,c4 ,,giulio4 ,the ,first ,consul1 in a letter to ,chaptal1 in which he announced to that minister the two prizes he had founded to encourage philosophers to make new researches in regard to ,galvanism1 says1 8,galvanism1 in my opinion1 will lead to great discoveries40 ,this observation was just and profound3 great discoveries have already been made2 ,galvani and ,volta have immortalized their names1 and several celebrated philosophers and physiologists have rendered themselves illustrious in this branch of science1 so abundant in astonishing phnomena3 yet it is only in its infancy1 and there can be no doubt that many important discoveries still remain to be made4 ,vassali1 ,rossi1 and myself1 have for several years been employed in researches on this subject4 ,while the first examined the ,galvanic fluid in every point of view1 for the purpose of illustrating its nature by means of a great number of ingenious experiments1 performed with that care and exactness for which he is distinguished1 ,rossi and ,i attempted to explain the action of the ,galvanic fluid on the different organs of the animal conomy4 ,sometimes ,i was obliged to interrupt my researches by unfortunate circumstances1 and at others by my administrative functions3 but ,i have now resumed them2 and though success has not yet crowned our efforts by any brilliant discovery1 we trust1 and with confidence1 that we shall be able to add some valuable facts to the history of the animal conomy2 to rectify others2 to confirm facts already received2 and to extend the domain of an inexhaustible agent fertile in wonders4 ,volta had announced that the involuntary organs1 such as the heart1 the stomach1 the intestines1 the bladder and vessels1 are insensible to the ,galvanic action#ae3 but we have fully refuted this great physiological error4 ,unfortunately1 however1 the ,latin memoir containing the decisive experiments which we made on cold-blooded and warm-blooded animals in #agib1 presented to the ,academy soon after1 and which1 according to ,sue1 in his ,history of ,galvanism#af1 8are curious1 and contain very interesting observations10 did not appear till #ahja1 when it was printed in the last volume of the ,transactions of the ,academy4 ,in that interval ,grapengiesser found1 as we had done1 that ,galvanism1 by means of zinc and silver#ag1 has an influence on the peristaltic motion4 ,humboldt ascertained the ,galvanic action on the hearts of frogs1 lizards1 toads1 and fishes4 ,smuch observed the excitability of the heart by the ,galvanic fluid2 and ,fowler changed the pulsations of the heart without the immediate application to it of armatures1 and only by adapting them in warm-blooded animals to the recurrent nerve by means of the sympathetic#ah4 ,it is chiefly in regard to the experiments of these learned ,germans that the historian of ,galvanism states#ai1 that the involuntary vermicular motion of the intestines1 according to the acknowledgment of all physiologists1 obeys metallic irritation2 whence it follows1 says he1 that the ,italian philosophers have advanced an error when they said that ,galvanism exercises no action but on the muscles1 which depend on the will4 ,as an accurate and impartial historian1 how can ,sue accuse the ,italian philosophers indiscriminately of such an error1 since he had our memoir before him when employed on the second volume of his ,history of ,galvanism1 and since he gave a short account of my experiments in his first volume8 ,nay1 ,i gave an account of my experiments in a small work published in ,italian in #agib4 ,but as ,italian works are not much read in ,france1 and were less so at that period1 ,i should not have reproached ,c4 ,sue with this act of injustice1 and his incorrectness in regard to the ,italian philosophers1 had not my ,latin memoir been known to him1 as it had appeared in the ,transactions of the ,academy4 ,though we made a great many experiments before we attempted to combat a philosopher so justly celebrated as ,volta1 and to establish the influence of ,galvanism on the involuntary organs2 and though ,grapengiesser1 ,humboldt1 ,smuch1 ,fowler1 c4 ascertained this influence in certain cold-blooded and even warm-blooded animals2 an object of so much importance to physiology required to be extended and confirmed1 especially in man1 by new experiments4 ,we have been the more sensible of the necessity of establishing this fact in an incontestable manner1 either in regard to the involuntary organs in general1 or more particularly the heart1 as the celebrated ,aldini1 professor at ,bologna1 in an ,italian work replete with new facts and valuable experiments made on the bodies of decapitated criminals1 has been obliged to acknowledge that he was not able to obtain any contraction in that organ by means of the electro-motor of ,volta1 which is so powerful4 ,we shall give an account1 in particular memoirs1 of the experiments we have already made1 and of those which we propose to perform4 ,in regard to the stomach1 the large and the small intestines1 and the bladder1 we shall say only1 in a general manner1 that by armature of the different nervous branches we obtained contractions analogous to those described in regard to animals4 ,the ,galvanic action on the heart and arteries is the object of the present paper1 as it is of the utmost importance to physiology1 and deserves1 under every point of view1 to excite our attention and occupy our reflections4 ,our experiments on the different parts of the head and trunk of the decapitated criminals were begun1 on the #ajth of ,august1 in a hall of the large hospital of ,st4 ,john1 and resumed and continued yesterday in the anatomical theatre of the university1 before a great number of spectators4 ,we tried the influence of ,galvanism on the heart in three different ways3 #ast1 ,in arming the spinal marrow by means of a cylinder of lead introduced into the canal of the cervical vertebr1 and then conveying one extremity of a silver arc over the surface of the heart1 and the other to the arming of the spinal marrow4 ,the heart of the first individual subjected to our experiments immediately exhibited very visible and very strong contractions4 ,these experiments were made without the intervention of any kind of pile1 and without any armature applied to the heart4 ,it is very remarkable1 that when the former is touched first1 and then the arming and spinal marrow1 the contractions of the heart which follow are more instantaneous1 and stronger1 than when the arming of the spinal marrow is first touched1 and then the heart4 ,in a memoir on ,galvanism1 read in the last public sitting of the academy1 ,i gave an account of a great number of experiments1 made especially on frogs1 which exhibited a similar phnomenon4 ,in these animals ,i observed1 a great number of times1 that when the arming of the crural nerves was touched first1 and then the muscles of the thigh1 there were no contractions1 or the contractions were exceedingly weak2 and1 on the other hand1 that when the muscles of the thighs were first touched1 and then the arming of the crural nerves1 as long as the least vitality remained in the organs1 the contractions of the muscles were constant and violent4 ,in the memoir already mentioned ,i have endeavoured to account for this phnomenon1 to which ,i shall recur1 when it has been ascertained by a sufficient number of trials1 that it is as general in men as ,i found it in frogs and other cold-blooded animals4 ,the second manner in which we tried the influence of ,galvanism on the heart was by arming the par vagum and the great sympathetic nerve4 ,the object of these experiments will be readily comprehended by anatomists acquainted with the details of neurology4 ,in these1 as well as in the first and other experiments where we armed the cardiac nerves themselves1 we obtained contractions in the heart4 ,in this1 as in the former case1 the contractions took place when the heart was first touched1 and then the arming of the nerves1 were much stronger than when the arming of the nerves was touched first1 and then the heart4 ,in this method we even observed that the ,galvanic experiments sometimes failed4 ,the third kind of experiments on the heart were performed by means of the pile4 ,the pile employed on the #ajth of ,august1 for the experiments on the first decapitated criminal1 was composed of fifty plates of silver and as many of zinc1 with pasteboard moistened by a strong solution of muriate of soda4 ,the silver was mixed with a tenth part of copper4 ,this is the proportion which we found most favourable to the intensity of the signs of ,galvanism3 ,metre4 ,the diameter of the silver plates was #jjcf ,their thickness #jjjae ,the dimensions of the pieces of pasteboard were the same4 ,metre4 ,the diameter of the zinc plates was #jjdb ,their thickness #jjjce ,the pile employed for the experiments on the #aeth of ,august was composed of fifty plates of pure silver1 and twice that number of plates of zinc and pieces of pasteboard2 the latter moistened in a solution of muriate of soda4 ,metre4 ,the diameter of the silver plates was #jjch ,their thickness #jjja ,the dimensions of the pieces of pasteboard were the same4 ,metre4 ,the diameter of the zinc plates was #jjd ,their thickness #jjja ,by making the negative extremity of the pile to communicate1 by means of respective conductors1 with the spinal marrow1 or merely with the muscles of the back or breast1 laid bare1 and the positive extremity immediately with the heart1 instantaneous and violent contractions were obtained2 and the contractions were produced also when the heart was made to communicate with the negative extremity of the pile1 and the spinal marrow with the positive extremity4 ,we shall observe1 in regard to contractions of the heart1 that of all its parts the apex is the most susceptible of motion1 and the most sensible to the ,galvanic influence3 we must observe also1 that the contractions produced by communication with the pile were not only strong1 but that they continued a long time even after the communication was destroyed4 ,a very remarkable circumstance is1 that the heart1 which of all the muscles retains longest1 in general1 its contractility in regard to mechanical stimulants1 is the first to become insensible to the ,galvanic influence4 ,the muscles of the arms1 and those of the back and breast1 continue to be excitable by ,galvanism for whole hours2 and the heart had lost its excitability about forty minutes after death4 ,the experiments made yesterday in the anatomical theatre exhibited nearly the same results in regard to the heart as those already mentioned4 ,the great arteries1 such as the aorta and some of its branches1 being injected with water raised nearly to the same temperament as that of the blood in the living individual1 and subjected to the ,galvanic action1 exhibited contractions4 ,but it is probable that they will appear stronger when trials of this kind shall be made on bodies endowed with a higher degree of vitality than those of yesterday1 and when the interval between the period of decapitation and that of the experiments shall be less4 ,with this view1 indeed1 we have provided a hall much nearer to the place of execution2 for the results which we obtained in the man decapitated on the #ajth of ,august1 in which case the experiments were begun five minutes after the decapitation1 were all comparatively more striking1 and stronger1 than those obtained in the experiments of yesterday1 which were begun more than twenty minutes after decapitation1 and which were performed1 as appears1 on bodies endowed with a much less degree of vitality4 ,in the experiments made on the arteries1 we armed the nervous plexuses1 which envelop the trunks of the cliac and mesenteric arteries1 several branches of which are even interwoven around the aorta3 a communication was established between the positive or negative extremity of the pile and the aortic artery itself4 ,it was by these means that we obtained visible contractions4 ,if the effects of ,galvanism on arterial contractions be constant1 as ,i suppose them to be1 all those discussions which have been agitated so long1 and with so much violence1 in regard to the irritability of the arteries1 which does not manifest itself by the action of different mechanical and chemical stimulants1 will at length be terminated in a positive and irrefragable manner2 all doubts will at length be removed2 and we shall be indebted to the ,galvanic fluid1 which is the most energetic of all agents applied to the animal fibre1 for having fixed the opinions of physiologists on a point of so much importance to the animal conomy4 ,whence comes it that ,aldini1 even with the help of the most powerful electro-motors1 was not able to obtain contractions in the heart of man1 which we so evidently obtained by the same means which always withstood his efforts8 ,how happens it that we obtained contractions by means much weaker8 ,the first experiments of ,aldini on the human heart were begun an hour and a half after death#bj4 ,the trunk had been exposed a long time to the open air1 the temperature of which was no more than #b4 ,it is probable that the cold1 and the long interval between the period of death and that of the experiment1 had already annihilated the irritability of the heart#ba4 ,in the fifty-third experiment1 the heart of another executed criminal constantly remained motionless and insensible to the ,galvanic current4 ,but in this experiment1 before trying the heart1 a considerable time was employed in making trials on the voluntary organs1 the sensibility of which to ,galvanism had already been acknowledged4 ,but the very reverse of this method ought to be followed2 for ,i will here repeat1 that excitability1 by means of the ,galvanic fluid1 is extinguished in the heart a long time before it becomes extinct in the voluntary muscles4 ,this is so certain1 that while no part of the heart1 tried externally and internally1 presented any sign of contractions1 the diaphragm1 and the muscles of the upper and lower extremities1 gave very strong ones4 ,in our experiments which were begun five minutes after death1 the heart ceased to be sensible to the ,galvanic agent about the fortieth minute2 and this was the case in the temperature of #be2 while the voluntary muscles retained their ,galvanic excitability for hours4 ,in other experiments made by ,aldini1 the contractility of the voluntary muscles existed three hours1 and even five hours1 after death4 ,in the oxen subjected to ,galvanic experiments by ,aldini1 the excitability of the heart must have been extinguished sooner1 since the action of the ,galvanic fluid of the pile produced no contractions1 though applied immediately after death4 ,if contractions were observed in the voluntary muscles under the same circumstances1 it was because these muscles1 which lose much sooner than the heart their excitability in regard to mechanical stimulants1 retain it much longer than that organ in regard to the ,galvanic agent4 ,what then is the cause of this diversity1 which seems contrary to every analogy1 and which1 however1 is proved by facts8 ,it is still involved in much obscurity3 but it is not yet time to tear the dark veil which conceals it2 we are not yet enlightened by a sufficient number of facts2 and the few scattered data which we have been able to collect1 cannot yet be connected in a manner capable of encouraging us to attempt to rend the veil at present4 ,we shall not here speak of the astonishment with which the spectators were struck when they saw the contractions of the frontal muscles1 those of the eye-lids1 the face1 the lower jaw1 and the tongue2 when they beheld the convulsions of the muscles of the arms1 the breast1 and of the back1 which raised the trunk some inches from the table2 the contractions of the pectoral muscles1 and the exterior and interior intercostal muscles1 which diminished the intervals between all the ribs1 and made them approach each other with violence1 raising the inferior ones towards the superior1 and the latter towards the first rib and the clavicle2 the contractions of the arms1 which1 when the uncovered biceps muscle was touched1 as well as its tendon1 were so speedy and violent1 that complete flexion of the fore-arm on the arm took place1 and that the hand raised weights of some pounds fifty minutes after decapitation4 ,similar experiments may be seen in the work of ,aldini3 our object in this report was merely to speak of the ,galvanic influence on the heart and arteries of man1 which had not yet been observed4 ,these new and important results1 which we obtained in regard to the heart and arteries of man1 will be confirmed by other trials4 ,we shall repeat our experiments as soon as an opportunity occurs1 and we shall take care to give you an early account of the most remarkable observations we shall make4 #ae ,mezzini1 ,volta1 ,valli1 ,klein1 ,pfaff1 ,berhends1 have denied that the heart could be moved by the ,galvanic fluid4 ,hist4 du ,galvanisme1 part i4 p4 #ade4 ,bichat could obtain no contractions either in the heart of man or that of the dog4 ,see ,rcherches ,physiologiques sur la ,vie et la ,mort4 #af ,towards the end of the ,first ,part4 #ag ,see ,histoire du ,galvanisme1 vol4 ii4 p4 #ha4 #ah ,ibid4 vol4 ii4 p4 #hd4 #ai ,vol4 ii4 p4 #hc4 #bj ,saggio di ,sperienze sul ,galvanismo di ,giovani ,aldini2 ,bolonia #ahjb1 p4 #ad1 esp4 #bh4 #ba ,if the celebrated ,bichat failed in his experiments on the human heart1 as well as ,aldini1 it was1 perhaps1 owing to the same causes4 ,the temperature was cold1 and the interval between the time of execution and that of the experiment too long4 8,i was authorized10 says ,bichat1 8in the winter of the year #g1 to make various trials on the bodies of unfortunate persons who had been guillotined4 ,i had them at my disposal from thirty to forty minutes after execution4 ,it was always impossible for me to produce the least motion by arming either the spinal marrow and the heart1 or the latter organ and the nerves which it receives from the ganglions by the sympathetic1 or from the brain by the par vagum40 ,no4 ,,iii4 ,account of an experiment made at ,calais1 on the transmission of ,galvanism through an arm of the sea4 ,by ,j4 ,,aldini4 ,the experiments made at the ,lake of ,geneva by ,mr4 de ,luc and his brother1 and those made in ,england on the banks of the ,thames1 by which it has been proved that common electricity is susceptible of transmission through a considerable space of water1 induced me to try some analogous experiments in regard to ,galvanism by endeavouring to make it traverse a certain extent of sea4 ,some philosophers1 to whom ,i communicated this project1 seemed to entertain doubts on the subject1 as they conceived that a considerable extent of sea water might perhaps destroy or impede the action of the ,galvanic fluid4 ,my late passage at ,calais afforded me an opportunity of removing all these doubts by an experiment which was attended with complete success4 ,m4 ,sept-,fontaines1 distinguished by his philosophical knowledge1 was desirous of assisting me in my proposed researches2 ,m4 ,cheely1 chemist of the military hospital1 prepared the necessary instruments2 and ,m4 ,debaudre1 the port engineer1 conducted the arrangement of the ,galvanic arcs4 ,on the #bgth of ,february1 the sky being serene1 and the sea calm1 every thing seemed to be favourable for the experiment4 ,a gentle south-west wind prevailed at the time2 the temperature of the water of the sea was #dgd of ,fahrenheit1 that of the atmosphere #did1 and the barometer stood at #cjcg inches4 ,fort ,rouge and the ,west ,mole afforded me two fixed points proper for my purpose4 ,a ,galvanic pile consisting of eighty plates of silver and zinc was constructed on the ,west ,mole on an insulated stool1 and the animals destined to be exposed to the ,galvanic action were placed at ,fort ,rouge4 ,the ,galvanic chain was composed of the arm of the sea which separates ,fort ,rouge from the ,western ,mole1 and of three wires disposed in the following manner4 ,the first wire proceeded from the base of the pile1 and1 being supported by an insulator1 fell vertically into the sea to the depth of about three fathoms4 ,the second wire1 insulated in the same manner1 proceeded from the summit of the pile1 and was conveyed in a horizontal direction at the height of from six to nine feet above the surface of the sea1 as far as the platform of ,fort ,rouge4 ,a third wire1 also insulated1 and placed at one corner of the platform1 descended perpendicularly into the sea in the same manner as the first4 ,when this arrangement was made1 if a person on the platform touched the extremities of the second and third wires1 and thus completed the ,galvanic circle1 he always experienced a shock2 and when animals recently killed were substituted in the room of the person1 they were thrown into strong convulsions4 ,we therefore concluded that the portion of sea water between the pile and the animal subjected to its action formed a part of the ,galvanic circle3 such was the consequence we thought ourselves authorised to deduce from this experiment4 ,the breadth of the water was about #bjj feet4 ,i must freely confess1 that in repeating these experiments1 we found1 that to receive the shock1 it was not absolutely necessary that the person should hold in his hands the two conductors1 and that it was sufficient to touch the wire alone which proceeded from the summit of the pile4 ,this apparent anomaly deranged at first the result of my researches2 and we suspected that the shocks before received had been transmitted without the intervention of the water of the sea4 ,it was therefore necessary that this doubt should be cleared up by new observations4 ,i tried separately1 on the platform1 the action of the two conducting wires1 and found that by touching the wire which fell into the sea no shock was produced4 ,i then took in my hand the other wire1 which proceeded from the summit of the pile2 and having thus brought its action into equilibrium1 ,i experienced a shock3 which shows that the ,galvanic fluid took its course from the bottom of the pile traversing the sea4 ,m4 ,sept-,fontaines proposed that we should lower to the level of the sea the wire which proceeded from the summit of the pile1 and which was extended to ,fort ,rouge4 ,the action of the ,galvanism was then checked1 but was immediately restored by placing the conductor in its former position4 ,thus1 notwithstanding the large extent of water by which the metallic conductors were separated2 and notwithstanding the agitation produced by the sea1 the ,galvanism found no obstacle to its propagation1 and pursued its usual direction4 ,hence it may be readily perceived1 that though the experiments here described are analogous to those formerly made with the ,leyden flask on lakes and rivers1 they are new of their kind1 and may contribute to establish the similarity between the properties of common electricity and of ,galvanism4 ,i will even venture to assert1 that these experiments1 if pursued and varied1 may lead to some interesting discoveries in natural philosophy4 ,after making these observations at ,fort ,rouge1 ,i repaired in company with ,m4 ,sept-,fontaines to the ,west ,mole1 to try the power of the pile unconnected with the sea4 ,having formed an arc1 we found that the action of the pile1 in this case1 was stronger2 which induced us to conclude1 that the ,galvanic power in traversing the sea had been in some measure weakened4 ,there is reason to suppose1 that by transmitting the ,galvanic influence gradually to greater distances through the sea1 the point of the minimum of its action1 that is1 a distance at which it will no longer be sensible1 may be discovered4 ,this distance remains to be determined1 and also the difference between the propagation of common electricity in fresh water1 and that of ,galvanism in salt water4 ,i observed that the sea shore1 still moist after the water retires in consequence of the reflux1 is endowed with the power of conveying ,galvanism to very great distances4 ,i made several experiments on this subject with ,m4 ,bastide1 physician of ,calais1 who acknowledged that he had received very strong shocks1 the effects of which were sensible the day following4 ,,the ,,end4 ,wilks and ,taylor1 ,printers1 ,chancery-lane4 ,illustration3 ,pl4 #a ,illustration3 ,pl4 #b4 ,illustration3 ,pl4 #c4 ,illustration3 ,pl4 #d4 ,,books ,,printed ,,for ,,and ,,sold ,,by ,,cuthell ,,and ,,martin1 ,,holborn4 ,,la ,,grange',s 7,professor in the ,central ,schools of ,paris1 c47 ,manual of a ,course of ,chemistry1 or a ,series of ,experiments and ,illustrations1 necessary to form a complete ,course of that ,science1 #b vols4 #hvo4 illustrated with #ag ,plates by ,lowry1 #ahs4 in boards4 ,brisson's 7,professor of ,chemistry in the ,central ,schools of ,paris7 ,physical ,principles of ,chemistry1 to which is added a short ,appendix by the ,translator1 illustrated with ,seven large ,engravings by ,lowry1 #a vol4 #hvo4 #ajs4 #f;d4 boards4 ,morgagni on ,diseases1 translated by ,alexander1 #c vols4 #dto4 boards1 #al4 #afs4 ,monro's 7,dr4 ,alex4 senior7 ,works1 with his ,life1 and ,portrait by ,basire1 #dto4 boards1 #al4 #as4 ,gellert's ,metallurgic ,chymistry1 being a ,system of ,mineralogy in general1 and of all the ,arts arising from this ,science1 to the great ,improvement of ,manufactures1 and the most capital ,branches of ,trade and ,commerce1 ,theoretical and ,practical4 ,translated from the ,german1 #hvo4 with #d ,plates1 boards1 #fs4 ,gillespie's ,observations on the ,diseases which prevailed on board a ,part of his ,majesty's ,squadron on the ,leeward ,island ,station1 between ,november #agid and ,april #agif1 #hvo4 boards1 #es4 ,fontana's ,treatise on the ,venom of the ,viper1 on the ,american ,poisons1 and on the ,cherry ,laurel1 and some other ,vegetable ,poisons1 to which are annexed ,observations on the primitive ,structure of the ,animal ,body1 different ,experiments on the ,reproduction of the ,nerves1 and a ,description of a new ,canal of the ,eye1 with ,ten descriptive ,plates4 ,translated by ,skinner1 #b vols4 #abs4 boards4 ,fourcroy's ,system of ,chemical ,knowledge1 with the ,synoptic ,tables of ,chemistry1 translating by ,nicholson1 #aa vols4 #hvo4--,the ,synoptic ,tables are already printed1 ,price #al4 #as4 boards4 ,haller's ,first ,lines of ,physiology1 a new ,edition1 to which is added1 a ,translation of the ,index composed for the ,edinburgh ,edition printed under the ,inspection of ,dr4 ,william ,cullen1 neatly printed in #hvo4 boards1 #ajs4 #f;d4 ,swediaur's ,practical ,observations on ,venereal ,complaints1 to which are added1 ,an ,account of a new ,venereal ,disease which has lately appeared in ,canada2 and ,a ,pharmacopia ,syphilitica1 #hvo4 boards1 #ds4 ,the same ,book on fine paper1 boards1 #es4 ,shaw's ,essays for the ,improvement of ,arts1 ,manufactures1 and ,commerce1 by ,means of ,chemistry1 #hvo4 boards1 #es4 ,buchan's ,domestic ,medicine4 ,a new ,edition is in the ,press1 and will shortly appear4 ,clark's ,treatise on the ,prevention of ,diseases incident to ,horses1 to which are subjoined ,observations on some of the ,surgical and ,medical ,branches of ,farriery1 a new ,edition1 in #a vol4 #hvo4 boards1 #hs4 ,cooper's ,complete ,distiller1 containing the ,method of performing the various ,processes of ,distillation1 with ,descriptions of the several ,instruments1 c4 with a ,plate1 boards1 #cs4 #f;d4 ,chemical ,vocabulary and ,tables of the ,old and ,new ,nomenclature1 by ,de ,morveau1 ,lavoisier1 ,berthollet1 and ,fourcroy1 boards1 #ds4 ,bergman's ,physical and ,chemical ,essays1 translated from the original ,latin1 with ,notes and ,illustrations by ,dr4 ,cullen1 of ,dublin1 #c vols4 #hvo4 with ,plates1 #ahs4 boards4 ,bell's 7,benjamin7 ,system of ,surgery1 a new ,edition1 #g vols4 #hvo4 with many ,plates1 #cl4 #cs4 boards4 ,bell's 7,benjamin7 ,treatise on the ,hydrocele1 on ,sarcocele1 on ,cancer1 and other ,diseases of the ,testes1 #hvo4 with four ,plates1 #ds4 boards4 ,withering's ,systematic ,arrangement of ,british ,plants1 with an easy ,introduction to the ,study of ,botany1 illustrated by ,copper-plates1 #d vols4 #hvo4 boards1 #bl4 #bs4 ,transcriber's ,note3 ,words and phrases in italics are surrounded by underscores1 like this4 ,dialect1 obsolete and alternative spellings were left unchanged4 #8,economy' is spelled without an twice in the ,contents2 elsewhere it appears as #8conomy4' ,footnotes were renumbered sequentially and moved to the end of the section in which related anchors occur4 ,obvious printing errors1 such as backwards1 upside down1 unprinted1 or partially printed letters1 were corrected4 ,final stops missing at the end of abbreviations and sentences were added4 ,the following items were changed3 ,added missing page number 7#c7 to first entry of ,table of ,contents4 ,added missing close quote to footnote #ba4 ,changed comma to stop #8444printed in #hvo4 boards1444'