,,the ,,method ,,by ,,which ,,the ,,causes ,,of ,,the ,,present ,,and ,,past ,,conditions ,,of ,,organic ,,nature ,,are ,,to ,,be ,,discovered4--,,the ,,origination ,,of ,,living ,,beings ,lecture ,,iii4 7of ,,vi471 ,lectures ,to ,working ,men1 at the ,museum of ,practical ,geology1 #ahfc1 ,on ,darwin's work3 ,origin of ,species4 ,by ,thomas ,h4 ,huxley ,in the two preceding lectures ,i have endeavoured to indicate to you the extent of the subject-matter of the inquiry upon which we are engaged2 and now1 having thus acquired some conception of the ,past and ,present phenomena of ,organic ,nature1 ,i must now turn to that which constitutes the great problem which we have set before ourselves2--,i mean1 the question of what knowledge we have of the causes of these phenomena of organic nature1 and how such knowledge is obtainable4 ,here1 on the threshold of the inquiry1 an objection meets us4 ,there are in the world a number of extremely worthy1 well-meaning persons1 whose judgments and opinions are entitled to the utmost respect on account of their sincerity1 who are of opinion that ,vital ,phenomena1 and especially all questions relating to the origin of vital phenomena1 are questions quite apart from the ordinary run of inquiry1 and are1 by their very nature1 placed out of our reach4 ,they say that all these phenomena originated miraculously1 or in some way totally different from the ordinary course of nature1 and that therefore they conceive it to be futile1 not to say presumptuous1 to attempt to inquire into them4 ,to such sincere and earnest persons1 ,i would only say1 that a question of this kind is not to be shelved upon theoretical or speculative grounds4 ,you may remember the story of the ,sophist who demonstrated to ,diogenes in the most complete and satisfactory manner that he could not walk2 that1 in fact1 all motion was an impossibility2 and that ,diogenes refuted him by simply getting up and walking round his tub4 ,so1 in the same way1 the man of science replies to objections of this kind1 by simply getting up and walking onward1 and showing what science has done and is doing--by pointing to that immense mass of facts which have been ascertained and systematized under the forms of the great doctrines of ,morphology1 of ,development1 of ,distribution1 and the like4 ,he sees an enormous mass of facts and laws relating to organic beings1 which stand on the same good sound foundation as every other natural law2 and therefore1 with this mass of facts and laws before us1 therefore1 seeing that1 as far as organic matters have hitherto been accessible and studied1 they have shown themselves capable of yielding to scientific investigation1 we may accept this as proof that order and law reign there as well as in the rest of nature2 and the man of science says nothing to objectors of this sort1 but supposes that we can and shall walk to a knowledge of the origin of organic nature1 in the same way that we have walked to a knowledge of the laws and principles of the inorganic world4 ,but there are objectors who say the same from ignorance and ill-will4 ,to such ,i would reply that the objection comes ill from them1 and that the real presumption1 ,i may almost say the real blasphemy1 in this matter1 is in the attempt to limit that inquiry into the causes of phenomena which is the source of all human blessings1 and from which has sprung all human prosperity and progress2 for1 after all1 we can accomplish comparatively little2 the limited range of our own faculties bounds us on every side1--the field of our powers of observation is small enough1 and he who endeavours to narrow the sphere of our inquiries is only pursuing a course that is likely to produce the greatest harm to his fellow-men4 ,but now1 assuming1 as we all do1 ,i hope1 that these phenomena are properly accessible to inquiry1 and setting out upon our search into the causes of the phenomena of organic nature1 or1 at any rate1 setting out to discover how much we at present know upon these abstruse matters1 the question arises as to what is to be our course of proceeding1 and what method we must lay down for our guidance4 ,i reply to that question1 that our method must be exactly the same as that which is pursued in any other scientific inquiry1 the method of scientific investigation being the same for all orders of facts and phenomena whatsoever4 ,i must dwell a little on this point1 for ,i wish you to leave this room with a very clear conviction that scientific investigation is not1 as many people seem to suppose1 some kind of modern black art4 ,i say that you might easily gather this impression from the manner in which many persons speak of scientific inquiry1 or talk about inductive and deductive philosophy1 or the principles of the ,baconian philosophy4 ,i do protest that1 of the vast number of cants in this world1 there are none1 to my mind1 so contemptible as the pseudoscientific cant which is talked about the ,baconian philosophy4 ,to hear people talk about the great ,chancellor--and a very great man he certainly was1--you would think that it was he who had invented science1 and that there was no such thing as sound reasoning before the time of ,queen ,elizabeth4 ,of course you say1 that cannot possibly be true2 you perceive1 on a moment's reflection1 that such an idea is absurdly wrong1 and yet1 so firmly rooted is this sort of impression1--,i cannot call it an idea1 or conception1--the thing is too absurd to be entertained1--but so completely does it exist at the bottom of most men's minds1 that this has been a matter of observation with me for many years past4 ,there are many men who1 though knowing absolutely nothing of the subject with which they may be dealing1 wish1 nevertheless1 to damage the author of some view with which they think fit to disagree4 ,what they do1 then1 is not to go and learn something about the subject1 which one would naturally think the best way of fairly dealing with it2 but they abuse the originator of the view they question1 in a general manner1 and wind up by saying that1 ,after all1 you know1 the principles and method of this author are totally opposed to the canons of the ,baconian philosophy4 ,then everybody applauds1 as a matter of course1 and agrees that it must be so4 ,but if you were to stop them all in the middle of their applause1 you would probably find that neither the speaker nor his applauders could tell you how or in what way it was so2 neither the one nor the other having the slightest idea of what they mean when they speak of the ,baconian philosophy4 ,you will understand1 ,i hope1 that ,i have not the slightest desire to join in the outcry against either the morals1 the intellect1 or the great genius of ,lord ,chancellor ,bacon4 ,he was undoubtedly a very great man1 let people say what they will of him2 but notwithstanding all that he did for philosophy1 it would be entirely wrong to suppose that the methods of modern scientific inquiry originated with him1 or with his age2 they originated with the first man1 whoever he was2 and indeed existed long before him1 for many of the essential processes of reasoning are exerted by the higher order of brutes as completely and effectively as by ourselves4 ,we see in many of the brute creation the exercise of one1 at least1 of the same powers of reasoning as that which we ourselves employ4 ,the method of scientific investigation is nothing but the expression of the necessary mode of working of the human mind4 ,it is simply the mode at which all phenomena are reasoned about1 rendered precise and exact4 ,there is no more difference1 but there is just the same kind of difference1 between the mental operations of a man of science and those of an ordinary person1 as there is between the operations and methods of a baker or of a butcher weighing out his goods in common scales1 and the operations of a chemist in performing a difficult and complex analysis by means of his balance and finely-graduated weights4 ,it is not that the action of the scales in the one case1 and the balance in the other1 differ in the principles of their construction or manner of working2 but the beam of one is set on an infinitely finer axis than the other1 and of course turns by the addition of a much smaller weight4 ,you will understand this better1 perhaps1 if ,i give you some familiar example4 ,you have all heard it repeated1 ,i dare say1 that men of science work by means of ,induction and ,deduction1 and that by the help of these operations1 they1 in a sort of sense1 wring from ,nature certain other things1 which are called ,natural ,laws1 and ,causes1 and that out of these1 by some cunning skill of their own1 they build up ,hypotheses and ,theories4 ,and it is imagined by many1 that the operations of the common mind can be by no means compared with these processes1 and that they have to be acquired by a sort of special apprenticeship to the craft4 ,to hear all these large words1 you would think that the mind of a man of science must be constituted differently from that of his fellow men2 but if you will not be frightened by terms1 you will discover that you are quite wrong1 and that all these terrible apparatus are being used by yourselves every day and every hour of your lives4 ,there is a well-known incident in one of ,moliere's plays1 where the author makes the hero express unbounded delight on being told that he had been talking prose during the whole of his life4 ,in the same way1 ,i trust1 that you will take comfort1 and be delighted with yourselves1 on the discovery that you have been acting on the principles of inductive and deductive philosophy during the same period4 ,probably there is not one here who has not in the course of the day had occasion to set in motion a complex train of reasoning1 of the very same kind1 though differing of course in degree1 as that which a scientific man goes through in tracing the causes of natural phenomena4 ,a very trivial circumstance will serve to exemplify this4 ,suppose you go into a fruiterer's shop1 wanting an apple1--you take up one1 and1 on biting it1 you find it is sour2 you look at it1 and see that it is hard and green4 ,you take up another one1 and that too is hard1 green1 and sour4 ,the shopman offers you a third2 but1 before biting it1 you examine it1 and find that it is hard and green1 and you immediately say that you will not have it1 as it must be sour1 like those that you have already tried4 ,nothing can be more simple than that1 you think2 but if you will take the trouble to analyze and trace out into its logical elements what has been done by the mind1 you will be greatly surprised4 ,in the first place1 you have performed the operation of ,induction4 ,you found that1 in two experiences1 hardness and greenness in apples go together with sourness4 ,it was so in the first case1 and it was confirmed by the second4 ,true1 it is a very small basis1 but still it is enough to make an induction from2 you generalize the facts1 and you expect to find sourness in apples where you get hardness and greenness4 ,you found upon that a general law1 that all hard and green apples are sour2 and that1 so far as it goes1 is a perfect induction4 ,well1 having got your natural law in this way1 when you are offered another apple which you find is hard and green1 you say1 ,all hard and green apples are sour2 this apple is hard and green1 therefore this apple is sour4 ,that train of reasoning is what logicians call a syllogism1 and has all its various parts and terms1--its major premiss1 its minor premiss1 and its conclusion4 ,and1 by the help of further reasoning1 which1 if drawn out1 would have to be exhibited in two or three other syllogisms1 you arrive at your final determination1 ,i will not have that apple4 ,so that1 you see1 you have1 in the first place1 established a law by ,induction1 and upon that you have founded a ,deduction1 and reasoned out the special conclusion of the particular case4 ,well now1 suppose1 having got your law1 that at some time afterwards1 you are discussing the qualities of apples with a friend3 you will say to him1 ,it is a very curious thing1--but ,i find that all hard and green apples are sour6 ,your friend says to you1 ,but how do you know that8 ,you at once reply1 ,oh1 because ,i have tried it over and over again1 and have always found them to be so4 ,well1 if we were talking science instead of common sense1 we should call that an ,experimental ,verification4 ,and1 if still opposed1 you go further1 and say1 ,i have heard from the people in ,somersetshire and ,devonshire1 where a large number of apples are grown1 that they have observed the same thing4 ,it is also found to be the case in ,normandy1 and in ,north ,america4 ,in short1 ,i find it to be the universal experience of mankind wherever attention has been directed to the subject4 ,whereupon1 your friend1 unless he is a very unreasonable man1 agrees with you1 and is convinced that you are quite right in the conclusion you have drawn4 ,he believes1 although perhaps he does not know he believes it1 that the more extensive ,verifications are1--that the more frequently experiments have been made1 and results of the same kind arrived at1--that the more varied the conditions under which the same results have been attained1 the more certain is the ultimate conclusion1 and he disputes the question no further4 ,he sees that the experiment has been tried under all sorts of conditions1 as to time1 place1 and people1 with the same result2 and he says with you1 therefore1 that the law you have laid down must be a good one1 and he must believe it4 ,in science we do the same thing2--the philosopher exercises precisely the same faculties1 though in a much more delicate manner4 ,in scientific inquiry it becomes a matter of duty to expose a supposed law to every possible kind of verification1 and to take care1 moreover1 that this is done intentionally1 and not left to a mere accident1 as in the case of the apples4 ,and in science1 as in common life1 our confidence in a law is in exact proportion to the absence of variation in the result of our experimental verifications4 ,for instance1 if you let go your grasp of an article you may have in your hand1 it will immediately fall to the ground4 ,that is a very common verification of one of the best established laws of nature--that of gravitation4 ,the method by which men of science establish the existence of that law is exactly the same as that by which we have established the trivial proposition about the sourness of hard and green apples4 ,but we believe it in such an extensive1 thorough1 and unhesitating manner because the universal experience of mankind verifies it1 and we can verify it ourselves at any time2 and that is the strongest possible foundation on which any natural law can rest4 ,so much by way of proof that the method of establishing laws in science is exactly the same as that pursued in common life4 ,let us now turn to another matter 7though really it is but another phase of the same question71 and that is1 the method by which1 from the relations of certain phenomena1 we prove that some stand in the position of causes towards the others4 ,i want to put the case clearly before you1 and ,i will therefore show you what ,i mean by another familiar example4 ,i will suppose that one of you1 on coming down in the morning to the parlour of your house1 finds that a tea-pot and some spoons which had been left in the room on the previous evening are gone1--the window is open1 and you observe the mark of a dirty hand on the window-frame1 and perhaps1 in addition to that1 you notice the impress of a hob-nailed shoe on the gravel outside4 ,all these phenomena have struck your attention instantly1 and before two minutes have passed you say1 ,oh1 somebody has broken open the window1 entered the room1 and run off with the spoons and the tea-pot6 ,that speech is out of your mouth in a moment4 ,and you will probably add1 ,i know there has2 ,i am quite sure of it6 ,you mean to say exactly what you know2 but in reality what you have said has been the expression of what is1 in all essential particulars1 an ,hypothesis4 ,you do not 'know' it at all2 it is nothing but an hypothesis rapidly framed in your own mind6 ,and it is an hypothesis founded on a long train of inductions and deductions4 ,what are those inductions and deductions1 and how have you got at this hypothesis8 ,you have observed1 in the first place1 that the window is open2 but by a train of reasoning involving many ,inductions and ,deductions1 you have probably arrived long before at the ,general ,law--and a very good one it is--that windows do not open of themselves2 and you therefore conclude that something has opened the window4 ,a second general law that you have arrived at in the same way is1 that tea-pots and spoons do not go out of a window spontaneously1 and you are satisfied that1 as they are not now where you left them1 they have been removed4 ,in the third place1 you look at the marks on the window-sill1 and the shoemarks outside1 and you say that in all previous experience the former kind of mark has never been produced by anything else but the hand of a human being2 and the same experience shows that no other animal but man at present wears shoes with hob-nails on them such as would produce the marks in the gravel4 ,i do not know1 even if we could discover any of those missing links that are talked about1 that they would help us to any other conclusion6 ,at any rate the law which states our present experience is strong enough for my present purpose4--,you next reach the conclusion1 that as these kinds of marks have not been left by any other animals than men1 or are liable to be formed in any other way than by a man's hand and shoe1 the marks in question have been formed by a man in that way4 ,you have1 further1 a general law1 founded on observation and experience1 and that1 too1 is1 ,i am sorry to say1 a very universal and unimpeachable one1--that some men are thieves2 and you assume at once from all these premisses--and that is what constitutes your hypothesis--that the man who made the marks outside and on the window-sill1 opened the window1 got into the room1 and stole your tea-pot and spoons4 ,you have now arrived at a ',vera ,causa'2--you have assumed a ,cause which it is plain is competent to produce all the phenomena you have observed4 ,you can explain all these phenomena only by the hypothesis of a thief4 ,but that is a hypothetical conclusion1 of the justice of which you have no absolute proof at all2 it is only rendered highly probable by a series of inductive and deductive reasonings4 ,i suppose your first action1 assuming that you are a man of ordinary common sense1 and that you have established this hypothesis to your own satisfaction1 will very likely be to go off for the police1 and set them on the track of the burglar1 with the view to the recovery of your property4 ,but just as you are starting with this object1 some person comes in1 and on learning what you are about1 says1 ,my good friend1 you are going on a great deal too fast4 ,how do you know that the man who really made the marks took the spoons8 ,it might have been a monkey that took them1 and the man may have merely looked in afterwards4 ,you would probably reply1 ,well1 that is all very well1 but you see it is contrary to all experience of the way tea-pots and spoons are abstracted2 so that1 at any rate1 your hypothesis is less probable than mine4 ,while you are talking the thing over in this way1 another friend arrives1 one of that good kind of people that ,i was talking of a little while ago4 ,and he might say1 ,oh1 my dear sir1 you are certainly going on a great deal too fast4 ,you are most presumptuous4 ,you admit that all these occurrences took place when you were fast asleep1 at a time when you could not possibly have known anything about what was taking place4 ,how do you know that the laws of ,nature are not suspended during the night8 ,it may be that there has been some kind of supernatural interference in this case4 ,in point of fact1 he declares that your hypothesis is one of which you cannot at all demonstrate the truth1 and that you are by no means sure that the laws of ,nature are the same when you are asleep as when you are awake4 ,well1 now1 you cannot at the moment answer that kind of reasoning4 ,you feel that your worthy friend has you somewhat at a disadvantage4 ,you will feel perfectly convinced in your own mind1 however1 that you are quite right1 and you say to him1 ,my good friend1 ,i can only be guided by the natural probabilities of the case1 and if you will be kind enough to stand aside and permit me to pass1 ,i will go and fetch the police4 ,well1 we will suppose that your journey is successful1 and that by good luck you meet with a policeman2 that eventually the burglar is found with your property on his person1 and the marks correspond to his hand and to his boots4 ,probably any jury would consider those facts a very good experimental verification of your hypothesis1 touching the cause of the abnormal phenomena observed in your parlour1 and would act accordingly4 ,now1 in this suppositious case1 ,i have taken phenomena of a very common kind1 in order that you might see what are the different steps in an ordinary process of reasoning1 if you will only take the trouble to analyse it carefully4 ,all the operations ,i have described1 you will see1 are involved in the mind of any man of sense in leading him to a conclusion as to the course he should take in order to make good a robbery and punish the offender4 ,i say that you are led1 in that case1 to your conclusion by exactly the same train of reasoning as that which a man of science pursues when he is endeavouring to discover the origin and laws of the most occult phenomena4 ,the process is1 and always must be1 the same2 and precisely the same mode of reasoning was employed by ,newton and ,laplace in their endeavours to discover and define the causes of the movements of the heavenly bodies1 as you1 with your own common sense1 would employ to detect a burglar4 ,the only difference is1 that the nature of the inquiry being more abstruse1 every step has to be most carefully watched1 so that there may not be a single crack or flaw in your hypothesis4 ,a flaw or crack in many of the hypotheses of daily life may be of little or no moment as affecting the general correctness of the conclusions at which we may arrive2 but1 in a scientific inquiry1 a fallacy1 great or small1 is always of importance1 and is sure to be constantly productive of mischievous1 if not fatal results4 ,do not allow yourselves to be misled by the common notion that an hypothesis is untrustworthy simply because it is an hypothesis4 ,it is often urged1 in respect to some scientific conclusion1 that1 after all1 it is only an hypothesis4 ,but what more have we to guide us in nine-tenths of the most important affairs of daily life than hypotheses1 and often very ill-based ones8 ,so that in science1 where the evidence of an hypothesis is subjected to the most rigid examination1 we may rightly pursue the same course4 ,you may have hypotheses and hypotheses4 ,a man may say1 if he likes1 that the moon is made of green cheese3 that is an hypothesis4 ,but another man1 who has devoted a great deal of time and attention to the subject1 and availed himself of the most powerful telescopes and the results of the observations of others1 declares that in his opinion it is probably composed of materials very similar to those of which our own earth is made up3 and that is also only an hypothesis4 ,but ,i need not tell you that there is an enormous difference in the value of the two hypotheses4 ,that one which is based on sound scientific knowledge is sure to have a corresponding value2 and that which is a mere hasty random guess is likely to have but little value4 ,every great step in our progress in discovering causes has been made in exactly the same way as that which ,i have detailed to you4 ,a person observing the occurrence of certain facts and phenomena asks1 naturally enough1 what process1 what kind of operation known to occur in nature applied to the particular case1 will unravel and explain the mystery8 ,hence you have the scientific hypothesis2 and its value will be proportionate to the care and completeness with which its basis had been tested and verified4 ,it is in these matters as in the commonest affairs of practical life3 the guess of the fool will be folly1 while the guess of the wise man will contain wisdom4 ,in all cases1 you see that the value of the result depends on the patience and faithfulness with which the investigator applies to his hypothesis every possible kind of verification4 ,i dare say ,i may have to return to this point by-and-by2 but having dealt thus far with our logical methods1 ,i must now turn to something which1 perhaps1 you may consider more interesting1 or1 at any rate1 more tangible4 ,but in reality there are but few things that can be more important for you to understand than the mental processes and the means by which we obtain scientific conclusions and theories4 #a ,having granted that the inquiry is a proper one1 and having determined on the nature of the methods we are to pursue and which only can lead to success1 ,i must now turn to the consideration of our knowledge of the nature of the processes which have resulted in the present condition of organic nature4 ,here1 let me say at once1 lest some of you misunderstand me1 that ,i have extremely little to report4 ,the question of how the present condition of organic nature came about1 resolves itself into two questions4 ,the first is3 ,how has organic or living matter commenced its existence8 ,and the second is3 ,how has it been perpetuated8 ,on the second question ,i shall have more to say hereafter4 ,but on the first one1 what ,i now have to say will be for the most part of a negative character4 ,if you consider what kind of evidence we can have upon this matter1 it will resolve itself into two kinds4 ,we may have historical evidence and we may have experimental evidence4 ,it is1 for example1 conceivable1 that inasmuch as the hardened mud which forms a considerable portion of the thickness of the earth's crust contains faithful records of the past forms of life1 and inasmuch as these differ more and more as we go further down1--it is possible and conceivable that we might come to some particular bed or stratum which should contain the remains of those creatures with which organic life began upon the earth4 ,and if we did so1 and if such forms of organic life were preservable1 we should have what ,i would call historical evidence of the mode in which organic life began upon this planet4 ,many persons will tell you1 and indeed you will find it stated in many works on geology1 that this has been done1 and that we really possess such a record2 there are some who imagine that the earliest forms of life of which we have as yet discovered any record1 are in truth the forms in which animal life began upon the globe4 ,the grounds on which they base that supposition are these3--,that if you go through the enormous thickness of the earth's crust and get down to the older rocks1 the higher vertebrate animals--the quadrupeds1 birds1 and fishes--cease to be found2 beneath them you find only the invertebrate animals2 and in the deepest and lowest rocks those remains become scantier and scantier1 not in any very gradual progression1 however1 until1 at length1 in what are supposed to be the oldest rocks1 the animal remains which are found are almost always confined to four forms--',oldhamia'1 whose precise nature is not known1 whether plant or animal2 ',lingula'1 a kind of mollusc2 ',trilobites'1 a crustacean animal1 having the same essential plan of construction1 though differing in many details from a lobster or crab2 and ,hymenocaris1 which is also a crustacean4 ,so that you have all the ',fauna' reduced1 at this period1 to four forms3 one a kind of animal or plant that we know nothing about1 and three undoubted animals--two crustaceans and one mollusc4 ,i think1 considering the organization of these mollusca and crustacea1 and looking at their very complex nature1 that it does indeed require a very strong imagination to conceive that these were the first created of all living things4 ,and you must take into consideration the fact that we have not the slightest proof that these which we call the oldest beds are really so3 ,i repeat1 we have not the slightest proof of it4 ,when you find in some places that in an enormous thickness of rocks there are but very scanty traces of life1 or absolutely none at all2 and that in other parts of the world rocks of the very same formation are crowded with the records of living forms1 ,i think it is impossible to place any reliance on the supposition1 or to feel oneself justified in supposing that these are the forms in which life first commenced4 ,i have not time here to enter upon the technical grounds upon which ,i am led to this conclusion1--that could hardly be done properly in half a dozen lectures on that part alone2--,i must content myself with saying that ,i do not at all believe that these are the oldest forms of life4 ,i turn to the experimental side to see what evidence we have there4 ,to enable us to say that we know anything about the experimental origination of organization and life1 the investigator ought to be able to take inorganic matters1 such as carbonic acid1 ammonia1 water1 and salines1 in any sort of inorganic combination1 and be able to build them up into ,protein matter1 and that that ,protein matter ought to begin to live in an organic form4 ,that1 nobody has done as yet1 and ,i suspect it will be a long while before anybody does do it4 ,but the thing is by no means so impossible as it looks2 for the researches of modern chemistry have shown us--,i won't say the road towards it1 but1 if ,i may so say1 they have shown the finger-post pointing to the road that may lead to it4 ,it is not many years ago--and you must recollect that ,organic ,chemistry is a young science1 not above a couple of generations old1--you must not expect too much of it2 it is not many years ago since it was said to be perfectly impossible to fabricate any organic compound2 that is to say1 any non-mineral compound which is to be found in an organized being4 ,it remained so for a very long period2 but it is now a considerable number of years since a distinguished foreign chemist contrived to fabricate ,urea1 a substance of a very complex character1 which forms one of the waste products of animal structures4 ,and of late years a number of other compounds1 such as ,butyric ,acid1 and others1 have been added to the list4 ,i need not tell you that chemistry is an enormous distance from the goal ,i indicate2 all ,i wish to point out to you is1 that it is by no means safe to say that that goal may not be reached one day4 ,it may be that it is impossible for us to produce the conditions requisite to the origination of life2 but we must speak modestly about the matter1 and recollect that ,science has put her foot upon the bottom round of the ladder4 ,truly he would be a bold man who would venture to predict where she will be fifty years hence4 ,there is another inquiry which bears indirectly upon this question1 and upon which ,i must say a few words4 ,you are all of you aware of the phenomena of what is called spontaneous generation4 ,our forefathers1 down to the seventeenth century1 or thereabouts1 all imagined1 in perfectly good faith1 that certain vegetable and animal forms gave birth1 in the process of their decomposition1 to insect life4 ,thus1 if you put a piece of meat in the sun1 and allowed it to putrefy1 they conceived that the grubs which soon began to appear were the result of the action of a power of spontaneous generation which the meat contained4 ,and they could give you receipts for making various animal and vegetable preparations which would produce particular kinds of animals4 ,a very distinguished ,italian naturalist1 named ,redi1 took up the question1 at a time when everybody believed in it2 among others our own great ,harvey1 the discoverer of the circulation of the blood4 ,you will constantly find his name quoted1 however1 as an opponent of the doctrine of spontaneous generation2 but the fact is1 and you will see it if you will take the trouble to look into his works1 ,harvey believed it as profoundly as any man of his time2 but he happened to enunciate a very curious proposition--that every living thing came from an 'egg'2 he did not mean to use the word in the sense in which we now employ it1 he only meant to say that every living thing originated in a little rounded particle of organized substance2 and it is from this circumstance1 probably1 that the notion of ,harvey having opposed the doctrine originated4 ,then came ,redi1 and he proceeded to upset the doctrine in a very simple manner4 ,he merely covered the piece of meat with some very fine gauze1 and then he exposed it to the same conditions4 ,the result of this was that no grubs or insects were produced2 he proved that the grubs originated from the insects who came and deposited their eggs in the meat1 and that they were hatched by the heat of the sun4 ,by this kind of inquiry he thoroughly upset the doctrine of spontaneous generation1 for his time at least4 ,then came the discovery and application of the microscope to scientific inquiries1 which showed to naturalists that besides the organisms which they already knew as living beings and plants1 there were an immense number of minute things which could be obtained apparently almost at will from decaying vegetable and animal forms4 ,thus1 if you took some ordinary black pepper or some hay1 and steeped it in water1 you would find in the course of a few days that the water had become impregnated with an immense number of animalcules swimming about in all directions4 ,from facts of this kind naturalists were led to revive the theory of spontaneous generation4 ,they were headed here by an ,english naturalist1--,needham1--and afterwards in ,france by the learned ,buffon4 ,they said that these things were absolutely begotten in the water of the decaying substances out of which the infusion was made4 ,it did not matter whether you took animal or vegetable matter1 you had only to steep it in water and expose it1 and you would soon have plenty of animalcules4 ,they made an hypothesis about this which was a very fair one4 ,they said1 this matter of the animal world1 or of the higher plants1 appears to be dead1 but in reality it has a sort of dim life about it1 which1 if it is placed under fair conditions1 will cause it to break up into the forms of these little animalcules1 and they will go through their lives in the same way as the animal or plant of which they once formed a part4 ,the question now became very hotly debated4 ,spallanzani1 an ,italian naturalist1 took up opposite views to those of ,needham and ,buffon1 and by means of certain experiments he showed that it was quite possible to stop the process by boiling the water1 and closing the vessel in which it was contained4 ,oh6 said his opponents2 but what do you know you may be doing when you heat the air over the water in this way8 ,you may be destroying some property of the air requisite for the spontaneous generation of the animalcules4 ,however1 ,spallanzani's views were supposed to be upon the right side1 and those of the others fell into discredit2 although the fact was that ,spallanzani had not made good his views4 ,well1 then1 the subject continued to be revived from time to time1 and experiments were made by several persons2 but these experiments were not altogether satisfactory4 ,it was found that if you put an infusion in which animalcules would appear if it were exposed to the air into a vessel and boiled it1 and then sealed up the mouth of the vessel1 so that no air1 save such as had been heated to #bab degrees1 could reach its contents1 that then no animalcules would be found2 but if you took the same vessel and exposed the infusion to the air1 then you would get animalcules4 ,furthermore1 it was found that if you connected the mouth of the vessel with a red-hot tube in such a way that the air would have to pass through the tube before reaching the infusion1 that then you would get no animalcules4 ,yet another thing was noticed3 if you took two flasks containing the same kind of infusion1 and left one entirely exposed to the air1 and in the mouth of the other placed a ball of cotton wool1 so that the air would have to filter itself through it before reaching the infusion1 that then1 although you might have plenty of animalcules in the first flask1 you would certainly obtain none from the second4 ,these experiments1 you see1 all tended towards one conclusion--that the infusoria were developed from little minute spores or eggs which were constantly floating in the atmosphere1 which lose their power of germination if subjected to heat4 ,but one observer now made another experiment which seemed to go entirely the other way1 and puzzled him altogether4 ,he took some of this boiled infusion that ,i have been speaking of1 and by the use of a mercurial bath--a kind of trough used in laboratories--he deftly inverted a vessel containing the infusion into the mercury1 so that the latter reached a little beyond the level of the mouth of the 'inverted' vessel4 ,you see that he thus had a quantity of the infusion shut off from any possible communication with the outer air by being inverted upon a bed of mercury4 ,he then prepared some pure oxygen and nitrogen gases1 and passed them by means of a tube going from the outside of the vessel1 up through the mercury into the infusion2 so that he thus had it exposed to a perfectly pure atmosphere of the same constituents as the external air4 ,of course1 he expected he would get no infusorial animalcules at all in that infusion2 but1 to his great dismay and discomfiture1 he found he almost always did get them4 ,furthermore1 it has been found that experiments made in the manner described above answer well with most infusions2 but that if you fill the vessel with boiled milk1 and then stop the neck with cotton-wool1 you 'will' have infusoria4 ,so that you see there were two experiments that brought you to one kind of conclusion1 and three to another2 which was a most unsatisfactory state of things to arrive at in a scientific inquiry4 ,some few years after this1 the question began to be very hotly discussed in ,france4 ,there was ,m4 ,pouchet1 a professor at ,rouen1 a very learned man1 but certainly not a very rigid experimentalist4 ,he published a number of experiments of his own1 some of which were very ingenious1 to show that if you went to work in a proper way1 there was a truth in the doctrine of spontaneous generation4 ,well1 it was one of the most fortunate things in the world that ,m4 ,pouchet took up this question1 because it induced a distinguished ,french chemist1 ,m4 ,pasteur1 to take up the question on the other side2 and he has certainly worked it out in the most perfect manner4 ,i am glad to say1 too1 that he has published his researches in time to enable me to give you an account of them4 ,he verified all the experiments which ,i have just mentioned to you--and then finding those extraordinary anomalies1 as in the case of the mercury bath and the milk1 he set himself to work to discover their nature4 ,in the case of milk he found it to be a question of temperature4 ,milk in a fresh state is slightly alkaline2 and it is a very curious circumstance1 but this very slight degree of alkalinity seems to have the effect of preserving the organisms which fall into it from the air from being destroyed at a temperature of #bab degrees1 which is the boiling point4 ,but if you raise the temperature #aj degrees when you boil it1 the milk behaves like everything else2 and if the air with which it comes in contact1 after being boiled at this temperature1 is passed through a red-hot tube1 you will not get a trace of organisms4 ,he then turned his attention to the mercury bath1 and found on examination that the surface of the mercury was almost always covered with a very fine dust4 ,he found that even the mercury itself was positively full of organic matters2 that from being constantly exposed to the air1 it had collected an immense number of these infusorial organisms from the air4 ,well1 under these circumstances he felt that the case was quite clear1 and that the mercury was not what it had appeared to ,m4 ,schwann to be1--a bar to the admission of these organisms2 but that1 in reality1 it acted as a reservoir from which the infusion was immediately supplied with the large quantity that had so puzzled him4 ,but not content with explaining the experiments of others1 ,m4 ,pasteur went to work to satisfy himself completely4 ,he said to himself3 ,if my view is right1 and if1 in point of fact1 all these appearances of spontaneous generation are altogether due to the falling of minute germs suspended in the atmosphere1--why1 ,i ought not only to be able to show the germs1 but ,i ought to be able to catch and sow them1 and produce the resulting organisms4 ,he1 accordingly1 constructed a very ingenious apparatus to enable him to accomplish this trapping of this germ dust in the air4 ,he fixed in the window of his room a glass tube1 in the centre of which he had placed a ball of gun-cotton1 which1 as you all know1 is ordinary cotton-wool1 which1 from having been steeped in strong acid1 is converted into a substance of great explosive power4 ,it is also soluble in alcohol and ether4 ,one end of the glass tube was1 of course1 open to the external air2 and at the other end of it he placed an aspirator1 a contrivance for causing a current of the external air to pass through the tube4 ,he kept this apparatus going for four-and-twenty hours1 and then removed the 'dusted' gun-cotton1 and dissolved it in alcohol and ether4 ,he then allowed this to stand for a few hours1 and the result was1 that a very fine dust was gradually deposited at the bottom of it4 ,that dust1 on being transferred to the stage of a microscope1 was found to contain an enormous number of starch grains4 ,you know that the materials of our food and the greater portion of plants are composed of starch1 and we are constantly making use of it in a variety of ways1 so that there is always a quantity of it suspended in the air4 ,it is these starch grains which form many of those bright specks that we see dancing in a ray of light sometimes4 ,but besides these1 ,m4 ,pasteur found also an immense number of other organic substances such as spores of fungi1 which had been floating about in the air and had got caged in this way4 ,he went farther1 and said to himself1 ,if these really are the things that give rise to the appearance of spontaneous generation1 ,i ought to be able to take a ball of this 'dusted' gun-cotton and put it into one of my vessels1 containing that boiled infusion which has been kept away from the air1 and in which no infusoria are at present developed1 and then1 if ,i am right1 the introduction of this gun-cotton will give rise to organisms4 ,accordingly1 he took one of these vessels of infusion1 which had been kept eighteen months1 without the least appearance of life1 and by a most ingenious contrivance1 he managed to break it open and introduce such a ball of gun-cotton1 without allowing the infusion or the cotton ball to come into contact with any air but that which had been subjected to a red heat1 and in twenty-four hours he had the satisfaction of finding all the indications of what had been hitherto called spontaneous generation4 ,he had succeeded in catching the germs and developing organisms in the way he had anticipated4 ,it now struck him that the truth of his conclusions might be demonstrated without all the apparatus he had employed4 ,to do this1 he took some decaying animal or vegetable substance1 such as urine1 which is an extremely decomposable substance1 or the juice of yeast1 or perhaps some other artificial preparation1 and filled a vessel having a long tubular neck with it4 ,he then boiled the liquid and bent that long neck into an ,s shape or zig-zag1 leaving it open at the end4 ,the infusion then gave no trace of any appearance of spontaneous generation1 however long it might be left1 as all the germs in the air were deposited in the beginning of the bent neck4 ,he then cut the tube close to the vessel1 and allowed the ordinary air to have free and direct access2 and the result of that was the appearance of organisms in it1 as soon as the infusion had been allowed to stand long enough to allow of the growth of those it received from the air1 which was about forty-eight hours4 ,the result of ,m4 ,pasteur's experiments proved1 therefore1 in the most conclusive manner1 that all the appearances of spontaneous generation arose from nothing more than the deposition of the germs of organisms which were constantly floating in the air4 ,to this conclusion1 however1 the objection was made1 that if that were the cause1 then the air would contain such an enormous number of these germs1 that it would be a continual fog4 ,but ,m4 ,pasteur replied that they are not there in anything like the number we might suppose1 and that an exaggerated view has been held on that subject2 he showed that the chances of animal or vegetable life appearing in infusions1 depend entirely on the conditions under which they are exposed4 ,if they are exposed to the ordinary atmosphere around us1 why1 of course1 you may have organisms appearing early4 ,but1 on the other hand1 if they are exposed to air from a great height1 or from some very quiet cellar1 you will often not find a single trace of life4 ,so that ,m4 ,pasteur arrived at last at the clear and definite result1 that all these appearances are like the case of the worms in the piece of meat1 which was refuted by ,redi1 simply germs carried by the air and deposited in the liquids in which they afterwards appear4 ,for my own part1 ,i conceive that1 with the particulars of ,m4 ,pasteur's experiments before us1 we cannot fail to arrive at his conclusions2 and that the doctrine of spontaneous generation has received a final 'coup de grace'4 ,you1 of course1 understand that all this in no way interferes with the 'possibility' of the fabrication of organic matters by the direct method to which ,i have referred1 remote as that possibility may be4 ,footnote #a3 ,those who wish to study fully the doctrines of which ,i have endeavoured to give some rough and ready illustrations1 must read ,mr4 ,john ,stuart ,mill's ',system of ,logic'4